Current Appointments & Affiliations
Assistant Professor of Biostatistics & Bioinformatics
·
2020 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Recent Publications
Single-cell and spatial detection of senescent cells using DeepScence.
Journal Article Cell Genom · December 10, 2025 Accurately identifying senescent cells is essential for studying their spatial and molecular features. We developed DeepScence, a method based on deep neural networks, to identify senescent cells in single-cell and spatial transcriptomics data. DeepScence ... Full text Link to item CiteIdentifying cell-type-specific spatially variable genes with ctSVG.
Journal Article Genome Biol · December 8, 2025 UNLABELLED: Spatially variable genes (SVGs) reveal the molecular and functional heterogeneity of cells across different spatial regions of a tissue. Sample-wide SVGs identified by existing methods largely overlap with cell-type marker genes derived from si ... Full text Open Access Link to item CiteVispro improves imaging analysis for Visium spatial transcriptomics.
Journal Article Genome Biol · June 18, 2025 Spatial transcriptomics enables spatially resolved gene expression analysis, but accompanying histology images are often degraded by fiducial markers and background regions, hindering interpretation. To address this, we introduce Vispro, an end-to-end auto ... Full text Link to item CiteRecent Grants
computational methods for spatial transcriptomics
ResearchPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2024 - 2029Perinatal Per- and Polyfluoroalkyl Substances (PFAS) exposure and Immunotoxicity
ResearchInvestigator · Awarded by National Institute of Environmental Health Sciences · 2023 - 2028NSF Engineering Research Center for Precision Microbiome Engineering (PreMiEr)
ResearchInvestigator · Awarded by National Science Foundation · 2022 - 2027View All Grants
Education, Training & Certifications
Johns Hopkins Unversity, Bloomberg School of Public Health ·
2020
Ph.D.