Biochemical Pharmacology

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  Publication Venue For

  • Inhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A 2A receptor mediated PI3K-Akt pathway.  130:83-92. 2017
  • Gene targeting in ischemic heart disease and failure: Translational and clinical studies.  85:1-11. 2013
  • Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance.  83:1084-1103. 2012
  • Attentional improvement in rats with the nicotinic agonist AZ12564698 (AZD3480).  82:1040-1041. 2011
  • Using zebrafish to fill the gap between in vitro and rodent models for nicotinic drug development.  82:1038-1039. 2011
  • A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells.  80:1754-1761. 2010
  • Regulator of G-protein signaling (RGS) proteins in cancer biology..  78:1289-1297. 2009
  • Acetaminophen normalizes glucose homeostasis in mouse models for diabetes..  75:1402-1410. 2008
  • Multiple brain pathways and receptors underlying tobacco addiction..  74:1263-1270. 2007
  • Nicotinic interactions with antipsychotic drugs, models of schizophrenia and impacts on cognitive function..  74:1182-1191. 2007
  • Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure..  71:497-520. 2006
  • Hypoxia impedes the formation of chromium DNA-adducts in a cell-free system..  70:1814-1822. 2005
  • Neuronal nitric oxide modulates morphine antinociceptive tolerance by enhancing constitutive activity of the mu-opioid receptor..  69:679-688. 2005
  • Inhibition of osteoclast differentiation and bone resorption by a novel lysophosphatidylcholine derivative, SCOH.  67:1239-1248. 2004
  • Pancreatic stellate cell migration: role of the phosphatidylinositol 3-kinase (PI3-kinase) pathway.  67:1215-1225. 2004
  • The development of morphine antinociceptive tolerance in nitric oxide synthase-deficient mice..  67:735-741. 2004
  • Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins..  67:77-85. 2004
  • Impact of a novel cardioprotective agent on the ischaemia-reperfusion-induced Akt kinase activation.  66:2263-2272. 2003
  • Sarin (nerve agent GB)-induced differential expression of mRNA coding for the acetylcholinesterase gene in the rat central nervous system..  65:2041-2047. 2003
  • Concentration dependent mitochondrial effect of amiodarone.  65:1115-1128. 2003
  • Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production.  64:1713-1724. 2002
  • Increased rate of glutathione synthesis from cystine in drug-resistant MCF-7 cells.  63:843-851. 2002
  • Protein levels of neurofilament subunits in the hen central nervous system following prevention and potentiation of diisopropyl phosphorofluoridate (DFP)-induced delayed neurotoxicity(1)..  63:11-19. 2002
  • Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease.  63:225-236. 2002
  • Domains of the parathyroid hormone (PTH) receptor required for regulation by G protein-coupled receptor kinases (GRKs)..  62:1047-1058. 2001
  • Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates..  60:83-90. 2000
  • Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8-tetrachlorodibenzo-p-dioxin..  59:997-1005. 2000
  • Influence of backbone chemistry on immune activation by synthetic oligonucleotides..  58:1981-1988. 1999
  • Enhanced mRNA expression of neurofilament subunits in the brain and spinal cord of diisopropyl phosphorofluoridate-treated hens..  57:1245-1251. 1999
  • Regulation of ryanodine receptors by reactive nitrogen species..  57:1079-1084. 1999
  • Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3..  56:1005-1012. 1998
  • Modes of interactions between signaling pathways..  55:1347-1352. 1998
  • Ras, superoxide and signal transduction..  55:1339-1346. 1998
  • Effect of receptor number on desensitization of the mouse thromboxane receptor..  55:1271-1281. 1998
  • Altered cyclic AMP-dependent human chorionic gonadotropin production in cultured human placental trophoblasts exposed to ethanol..  55:45-51. 1998
  • Human ovarian cancer of the surface epithelium..  54:541-544. 1997
  • Alteration in neurofilament axonal transport in the sciatic nerve of the diisopropyl phosphorofluoridate (DFP)-treated hen..  53:1799-1806. 1997
  • Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo. Inhibition of glyoxalase I and induction of apoptosis..  51:1365-1372. 1996
  • Effect of DNA conformation on cisplatin adduct formation..  51:717-721. 1996
  • Effects of 540C91 [(E)-3-[2-(4'-pyridyl)-vinyl]-1H-indole], an inhibitor of hepatic tryptophan dioxygenase, on brain quinolinic acid in mice..  51:159-163. 1996
  • Glutathione and glutathione S-transferase in benign and malignant prostate cell lines and prostate tissues..  51:87-90. 1996
  • Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine phase II [Ah] battery gene expression..  50:2057-2068. 1995
  • On the importance of the "antagonist assumption" to how receptors express themselves..  50:17-26. 1995
  • Relationship between cytochrome P450 2E1 and acetone catabolism in rats as studied with diallyl sulfide as an inhibitor..  48:2199-2205. 1994
  • A2a/D2 receptor interactions are not observed in COS-7 cells transiently transfected with dopamine D2 and adenosine A2a receptor cDNA..  48:2043-2047. 1994
  • Interaction of the regulatory domains of the murine Cyp1a1 gene with two DNA-binding proteins in addition to the Ah receptor and the Ah receptor nuclear translocator (ARNT)..  48:1767-1778. 1994
  • Correlation of total and interstrand DNA adducts in tumor and kidney with antitumor efficacies and differential nephrotoxicities of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin..  48:793-799. 1994
  • A_2a /D₂ receptor interactions are not observed in COS-7 cells transiently transfected with dopamine D₂ and adenosine A_2a receptor cDNA.  48:2043-2047. 1994
  • Effect of age and gender on the activity of human hepatic CYP3A..  44:275-283. 1992
  • Ca2+/calmodulin-dependent protein kinase II from hen brain. Purification and characterization..  43:1975-1988. 1992
  • Effects of buthionine sulfoximine and diethyl maleate on glutathione turnover in the channel catfish..  43:2209-2215. 1992
  • Ca²⁺ /calmodulin-dependent protein kinase II from hen brain. Purification and characterization.  43:1975-1988. 1992
  • Polyploidy induction as a consequence of topoisomerase inhibition. A flow cytometric assessment..  42:2199-2208. 1991
  • Persistent alterations of calmodulin kinase II activity in chickens after an oral dose of tri-o-cresyl phosphate..  42:171-180. 1991
  • Stimulation of secretion by the T84 colonic epithelial cell line with dietary flavonols..  41:1879-1886. 1991
  • Glutathione S-transferase-mediated chlorothalonil metabolism in liver and gill subcellular fractions of channel catfish..  42:139-145. 1991
  • Induction of cytochrome P450 isozymes by simultaneous inhalation exposure of hens to n-hexane and methyl iso-butyl ketone (MiBK)..  41:877-883. 1991
  • Elevation of rat pulmonary, hepatic and lung surfactant lipids by fly ash inhalation..  41:191-198. 1991
  • Effect of normal aging on the activity of human hepatic cytochrome P450IIE1..  40:1666-1669. 1990
  • Cofractionation of the 17-kD PK 14105 binding site protein with solubilized peripheral-type benzodiazepine binding sites..  40:983-989. 1990
  • Stimulation and inhibition of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced strand breaks and interstrand cross-linking in Col E1 plasmid deoxyribonucleic acid by polyamines and inorganic cations..  40:473-479. 1990
  • The new biology of drug receptors..  38:2941-2948. 1989
  • Microsomal and cytosolic epoxide hydrolase and glutathione S-transferase activities in the gill, liver, and kidney of the rainbow trout, Salmo gairdneri. Baseline levels and optimization of assay conditions..  38:881-887. 1989
  • Buthionine sulfoximine-mediated depletion of glutathione in intracranial human glioma-derived xenografts..  37:4313-4317. 1988
  • Effect of atrial natriuretic factor on brush border membrane transport of phosphate in phosphate-deprived rats..  37:4027-4029. 1988
  • The GABAA receptor-gated ion channel: biochemical and pharmacological studies of structure and function..  37:3369-3375. 1988
  • Inhibition of adenylosuccinate lyase by L-alanosyl-5-aminoimidazole-4-carboxylic acid ribonucleotide (alanosyl-AICOR)..  36:705-709. 1987
  • Relationship between binding affinity, retention and sensitivity of human rhabdomyosarcoma xenografts to Vinca alkaloids..  36:81-88. 1987
  • Chemical modification of alpha 2-adrenoceptors. Possible role for tyrosine in the ligand binding site..  35:4089-4094. 1986
  • Nucleic acid binding drugs--XIV. The crystal structure of 1-methyl amsacrine hydrochloride; relationships to DNA-binding ability and anti-tumour activity..  35:3915-3921. 1986
  • Depression of alcohol dehydrogenase activity in rat hepatocyte culture by dihydrotestosterone..  35:335-339. 1986
  • Interaction of 2,4-dichlorophenoxyacetate (2,4-D) and 2,4,5-trichlorophenoxyacetate (2,4,5-T) with the acyl-CoA: amino acid N-acyltransferase enzymes of bovine liver mitochondria..  35:289-295. 1986
  • Role of the pituitary and neonatal androgenic imprinting in the hormonal regulation of liver alcohol dehydrogenase activity.  35:1527-1532. 1986
  • Arylazide photoaffinity probe for alpha 2-adrenoceptors..  34:3667-3672. 1985
  • Effects of neonatal treatment with 6-aminonicotinamide on basal and isoproterenol-stimulated ornithine decarboxylase activity in cerebellum of the development rat..  34:3281-3284. 1985
  • Arachidonic acid metabolism in cultured aortic endothelial cells. Effect of cAMP and 3-isobutyl-1-methylxanthine..  34:119-123. 1985
  • Photoaffinity labeling of beta-adrenergic receptors in mammalian tissues..  33:3813-3822. 1984
  • Effects of pimozide and penfluridol on the binding and endocytosis of alpha 2-macroglobulin-CH3NH2 by mouse peritoneal macrophages..  33:3712-3714. 1984
  • Dopamine receptor of the porcine anterior pituitary gland. Solubilization and characterization..  33:1981-1988. 1984
  • Sex-related difference in the metabolism of isosorbide dinitrate following incubation in human blood..  32:3729-3734. 1983
  • Solubilization of rat liver alpha 1-adrenergic receptors. Agonist specific alteration in receptor binding affinity..  32:3171-3178. 1983
  • In vivo metabolism of reversibly inhibited alpha-thrombin..  32:739-741. 1983
  • Guanine nucleotides and alpha 1 adrenergic receptors in the heart..  32:69-71. 1983
  • Differential metabolism of O-ethyl O-4-nitrophenyl phenylphosphonothioate by rat and chicken hepatic microsomes..  31:1961-1967. 1982
  • Maternal methadone administration: deficit in development of alpha-noradrenergic responses in developing rat brain as assessed by norepinephrine stimulation of 33Pi incorporation into phospholipids in vivo..  31:1899-1902. 1982
  • Toxic effect of chlorisondamine in neonatal rat liver..  31:1798-1801. 1982
  • Effect of cyclooxygenase inhibitors and protease inhibitors on phorbol-induced stimulation of oxygen consumption and superoxide production by rat pulmonary macrophages..  31:775-780. 1982
  • pH dependence of [3H]norepinephrine uptake into catecholamine storage vesicles isolated from rat brain, heart and adrenal medulla..  30:2872-2873. 1981
  • Effects of dietary pectin and cellulose on hepatic and intestinal mixed-function oxidations and hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the rat..  30:2553-2558. 1981
  • Monoamine oxidase A and B activities in liver of riboflavin-deficient rats..  29:2693-2694. 1980
  • Maturation of sympathetic neurotransmission in the rat heart--III. Developmental changes in reserpine inhibition of norepinephrine uptake into isolated synaptic vesicles..  29:1595-1598. 1980
  • [3H]WB4101--caution about its role as an alpha-adrenergic subtype selective radioligand..  29:1537-1541. 1980
  • An assay for alpha-adrenergic receptor subtypes using [3H]dihydroergocryptine..  29:452-454. 1980
  • Subclassification of alpha-adrenergic receptors by direct binding studies..  28:1277-1282. 1979
  • Metabolism of amphetamine by rat brain tissue..  27:343-351. 1978
  • Role of acid phosphatase in delayed neurotoxicity induced by leptophos in hens..  27:2055-2058. 1978
  • Effect of maternal ethanol ingestion on neonatal rat brain and heart ornithine decarboxylase..  26:523-527. 1977
  • The question of cholinergic antagonism..  25:2761-2764. 1976
  • Catecholamine synthesis, storage and release in adrenal medulla and whole brain during acute and chronic methadone administration..  25:2523-2527. 1976
  • Effects of early postnatal guanethidine administration on adrenal medulla and brain of developing rats..  25:2387-2390. 1976
  • Effects of postnatal reserpine administration on sympatho-adrenal development in the rat..  25:1513-1519. 1976
  • p-Chlorophenylalanine-induced enhancement of the effects of morphine on the adrenal medulla..  25:1547-1548. 1976
  • Effects of chronic chlorisondamine administration on the sympatho-adrenal axis..  25:1311-1315. 1976
  • The role of neural input in the effects of morphine on the rat adrenal medulla..  25:1071-1074. 1976
  • Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists..  24:1651-1658. 1975
  • Inhibition of epinephrine and metaraminol uptake into adrenal medullary vesicles by aralkylamines and alkylamines.  24:1413-1419. 1975
  • Effects of morphine on the rat adrenal medulla..  24:671-679. 1975
  • Heterogeneity of adenylate cyclase-coupled beta-adrenergic receptors..  24:583-590. 1975
  • Adrenal medullary storage vesicles of the spontaneously hypertensive rat..  24:173-180. 1975
  • Maturation of the adrenal medulla. III. Practical and theoretical considerations of age-dependent alterations in kinetics of incorporation of catecholamines and non-catecholamines..  24:89-97. 1975
  • Commentary. Molecular pharmacology of beta-adrenergic receptors--a status report..  23:2069-2076. 1974
  • Drug-resistant effect of adenine nucleotides and magnesium on catecholamine efflux from isolated adrenal medullary storage vesicles..  23:2190-2192. 1974
  • Secretion and recovery of catecholamines by the adrenal medulla.  23:351-356. 1974
  • Toward isolation of a β adrenergic binding protein.  23:278-285. 1974
  • Binding of amines to purified bovine adrenal medullary storage vesicle membranes..  22:2492-2497. 1973
  • Maturation of the adrenal medulla. I. Uptake and storage of amines in isolated storage vesicles of the rat..  22:2023-2032. 1973
  • Maturation of the adrenal medulla. II. Content and properties of catecholamine storage vesicles of the rat..  22:2033-2044. 1973
  • Effects of reserpine on the content and properties of rat adrenal medullary storage vesicles..  22:549-560. 1973
  • All-or-none secretion of adrenal medullary storage vesicle contents in the rat..  22:205-219. 1973
  • Inhibition of liver alcohol dehydrogenase by primaquine and 8-amino-6-methoxyquinoline compounds.  21:17-25. 1972
  • Mechanism of methemoglobin formation by diphenylsulfones. Effect of 4-Amino-4′-hydroxyaminodiphenylsulfone and other p-substituted derivatives.  21:1265-1274. 1972
  • Structure-activity relationships of noreperidine congeners on cholinesterase systems in vitro and analgesia in vivo..  20:1167-1182. 1971
  • Urinary metabolities of harmine in the rat and their inhibition of monoamine oxidase..  19:125-131. 1970
  • The metabolism in vivo of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD) and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) in the chick by embryonic injection and dietary ingestion..  17:2143-2161. 1968
  • Comparative aspects of tyrosine hydroxylase and tryptophan hydroxylase inhibition: Arterenones and dihydroxyphenylacetamide (H 2254).  17:403-410. 1968
  • Difference in oral effectiveness of two tyrosine hydroxylase inhibitors.  16:401-403. 1967
  • The metabolism of 1-aminocyclopentane-1-carboxylic acid in normal and neoplastic tissues.  11:135-145. 1962
  • Nicotinic treatments not only for tobacco, but also other addictions 2015
  • Nicotinic α4β2 antagonist treatment attenuates impairments in radial-arm maze repeated acquisition caused by dizocilpine in rats 2013
  • Sazetidine-A, a nicotinic desensitizing agent, decreases nicotine self-administration in rats 2007