The Biochemical Journal

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  Publication Venue For

  • Engineering oxidative stability in human hemoglobin based on the Hb providence (βK82D) mutation and genetic cross-linking..  474:4171-4192. 2017
  • The C2 domain of Tollip, a Toll-like receptor signalling regulator, exhibits broad preference for phosphoinositides.  435:597-608. 2011
  • Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications..  431:113-122. 2010
  • Structure of a trimeric bacterial microcompartment shell protein, EtuB, associated with ethanol utilization in Clostridium kluyveri..  423:199-207. 2009
  • Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus..  419:555-564. 2009
  • Synergistic induction of nuclear factor-kappaB by transforming growth factor-beta and tumour necrosis factor-alpha is mediated by protein kinase A-dependent RelA acetylation..  417:583-591. 2009
  • Erratum: Expression and glycogenic effect of glycogen-targeting protein phosphatase 1 regulatory subunit GL in cultured human muscle (Biochemical Journal (2007) 405, (107-113)).  405:625. 2007
  • The high concentration of Arg213-->Gly extracellular superoxide dismutase (EC-SOD) in plasma is caused by a reduction of both heparin and collagen affinities..  385:427-432. 2005
  • The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity..  382:261-268. 2004
  • Characterization of the interaction between alpha2-macroglobulin and fibroblast growth factor-2: the role of hydrophobic interactions..  374:123-129. 2003
  • Structural and functional characterization of tissue factor pathway inhibitor following degradation by matrix metalloproteinase-8..  367:451-458. 2002
  • Phosphorylation of the myosin phosphatase target subunit by integrin-linked kinase..  366:211-216. 2002
  • Lysine(164)alpha of protein farnesyltransferase is important for both CaaX substrate binding and catalysis..  360:625-631. 2001
  • Characterization of the reaction mechanism for the XL-I form of bovine liver xenobiotic/medium-chain fatty acid:CoA ligase..  357:283-288. 2001
  • Response of neurons to an irreversible inhibition of endoplasmic reticulum Ca(2+)-ATPase: relationship between global protein synthesis and expression and translation of individual genes..  356:805-812. 2001
  • Interaction of plasminogen with dipeptidyl peptidase IV initiates a signal transduction mechanism which regulates expression of matrix metalloproteinase-9 by prostate cancer cells..  355:397-407. 2001
  • DNA repair protein O6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells..  351 Pt 2:393-402. 2000
  • Mutations of the serine phosphorylated in the protein phosphatase-1-binding motif in the skeletal muscle glycogen-targeting subunit..  346 Pt 1:77-82. 2000
  • The winged-helix/forkhead protein myocyte nuclear factor beta (MNF-beta) forms a co-repressor complex with mammalian sin3B..  345 Pt 2:335-343. 2000
  • Autocrine regulation of growth stimulation in human epithelial ovarian carcinoma by serine-proteinase-catalysed release of the urinary-type-plasminogen-activator N-terminal fragment..  341 ( Pt 3):765-769. 1999
  • Angiostatin inhibits endothelial and melanoma cellular invasion by blocking matrix-enhanced plasminogen activation..  340 ( Pt 1):77-84. 1999
  • AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target..  338 ( Pt 3):783-791. 1999
  • Interaction sites of the C-terminal region of the cGMP phosphodiesterase inhibitory subunit with the GDP-bound transducin alpha-subunit..  337 ( Pt 2):281-288. 1999
  • Regulation of membrane release in apoptosis..  334 ( Pt 2):479-485. 1998
  • Ambient but not incremental oxidant generation effects intercellular adhesion molecule 1 induction by tumour necrosis factor alpha in endothelium..  331 ( Pt 3):853-861. 1998
  • Temperature-sensitive mRNA degradation is an early event in hepatocyte de-differentiation..  328 ( Pt 3):937-944. 1997
  • Rac1 is required for cell proliferation and G2/M progression..  326 ( Pt 1):17-20. 1997
  • Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII)..  324 ( Pt 3):855-861. 1997
  • Assignment of a single disulphide bridge in human alpha2-antiplasmin: implications for the structural and functional properties..  323 ( Pt 3):847-852. 1997
  • Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins..  321 ( Pt 3):561-571. 1997
  • Influence of metal ions on substrate binding and catalytic activity of mammalian protein geranylgeranyltransferase type-I..  320 ( Pt 3):925-932. 1996
  • Regulation of reactive-oxygen-species generation in fibroblasts by Rac1..  318 ( Pt 2):379-382. 1996
  • Structural and functional analysis of the spontaneous re-formation of the thiol ester bond in human alpha 2-macroglobulin, rat alpha 1-inhibitor-3 and chemically modified derivatives..  318 ( Pt 2):539-545. 1996
  • Human extracellular superoxide dismutase is a tetramer composed of two disulphide-linked dimers: a simplified, high-yield purification of extracellular superoxide dismutase..  317 ( Pt 1):51-57. 1996
  • Chronic growth hormone treatment in normal rats reduces post-prandial skeletal muscle plasma membrane GLUT1 content, but not glucose transport or GLUT4 expression and localization..  315 ( Pt 3):959-963. 1996
  • ATP-regulated activity of the plasmin-streptokinase complex: a novel mechanism involving phosphorylation of streptokinase..  313 ( Pt 1):171-177. 1996
  • Zn2+ depletion blocks endosome fusion..  312 ( Pt 3):919-923. 1995
  • Primary structure and tissue-specific expression of blue crab (Callinectes sapidus) metallothionein isoforms..  311 ( Pt 2):617-622. 1995
  • Regulation of expression of transcobalamin II receptor in the rat..  310 ( Pt 3):923-929. 1995
  • Ligation of the alpha 2-macroglobulin signalling receptor on macrophages induces protein phosphorylation and an increase in cytosolic pH..  309 ( Pt 1):151-158. 1995
  • Amino acids important in enzyme activity and dimer stability forDrosophilaalcohol dehydrogenase.  308:419-423. 1995
  • Isolation and characterization of cDNA clones encoding pig gastric mucin..  308 ( Pt 1):89-96. 1995
  • Specific binding of urinary-type plasminogen activator (u-PA) to vitronectin and its role in mediating u-PA-dependent adhesion of U937 cells..  307 ( Pt 3):867-873. 1995
  • The primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin..  306 ( Pt 1):191-197. 1995
  • Adenovirus-mediated delivery into myocytes of muscle glycogen phosphorylase, the enzyme deficient in patients with glycogen-storage disease type V..  304 ( Pt 3):1009-1014. 1994
  • Determination of the mechanism of reaction for bile acid: CoA ligase..  304 ( Pt 3):945-949. 1994
  • Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells..  303 ( Pt 1):177-186. 1994
  • Isolation and characterization of fibronectin-alpha 1-microglobulin complex in rat plasma..  301 ( Pt 3):745-751. 1994
  • Ca(2+)-independent arachidonic acid release by vascular endothelium requires protein synthesis de novo..  300 ( Pt 2):449-455. 1994
  • Regulation of lipoprotein lipase activity and mRNA in the mammary gland of the lactating mouse..  298 ( Pt 2):321-327. 1994
  • Isolation of highly purified, functional endosomes from toad urinary bladder..  295 ( Pt 2):471-476. 1993
  • Isolation and characterization of renal cortical membranes using an aqueous two-phase partition technique..  292 ( Pt 3):743-748. 1993
  • Microinjection of Rap2B protein or RNA induces rearrangement of pigment granules in Xenopus oocytes..  292 ( Pt 1):231-236. 1993
  • An examination of the inhibitory mechanism of serpins by analysing the interaction of trypsin and chymotrypsin with alpha 2-antiplasmin..  291 ( Pt 3):933-938. 1993
  • Effect of temperature on bradykinin-induced arachidonate release and calcium mobilization in vascular endothelial cells..  291 ( Pt 3):803-809. 1993
  • Receptor-recognized alpha 2-macroglobulin-methylamine elevates intracellular calcium, inositol phosphates and cyclic AMP in murine peritoneal macrophages..  290 ( Pt 3):885-891. 1993
  • Identification of monomeric alpha-macroglobulin proteinase inhibitors in birds, reptiles, amphibians and mammals, and purification and characterization of a monomeric alpha-macroglobulin proteinase inhibitor from the American bullfrog Rana catesbeiana..  290 ( Pt 1):85-95. 1993
  • Structural comparison between the mitochondrial aralkyl-CoA and arylacetyl-CoA N-acyltransferases..  288 ( Pt 1):315-317. 1992
  • Lipoprotein (a) promotes plasmin inhibition by alpha 2-antiplasmin..  286 ( Pt 1):79-84. 1992
  • Renaturation and partial peptide sequencing of mitogen-activated protein kinase (MAP kinase) activator from rabbit skeletal muscle..  285 ( Pt 3):701-705. 1992
  • Purification and characterization of an alpha-macroglobulin proteinase inhibitor from the mollusc Octopus vulgaris..  285 ( Pt 2):521-527. 1992
  • Binding of human plasminogen to basement-membrane (type IV) collagen..  284 ( Pt 1):103-108. 1992
  • Effect of desialylation on the biological properties of human plasminogen..  284 ( Pt 1):81-86. 1992
  • Purification and analysis of proteinase-resistant mutants of recombinant platelet-derived growth factor-BB exhibiting improved biological activity..  281 ( Pt 1):57-65. 1992
  • Regulation of arachidonic acid release in vascular endothelium. Ca(2+)-dependent and -independent pathways..  280 ( Pt 2):281-287. 1991
  • Kinetic analysis of the effects of glycosaminoglycans and lipoproteins on urokinase-mediated plasminogen activation..  276 ( Pt 3):785-791. 1991
  • Trimethoprim resistance in Haemophilus influenzae is due to altered dihydrofolate reductase(s)..  274 ( Pt 3):657-662. 1991
  • Synthesis of intracellular histamine in platelets is associated with activation of protein kinase C, but not with mobilization of Ca2+..  273(Pt 2):405-408. 1991
  • SK&F 96365, a novel inhibitor of receptor-mediated calcium entry..  271:515-522. 1990
  • DNA fragmentation in permeabilized cells and nuclei. The role of (Ca2++ Mg2+)-dependent endodeoxyribonuclease.  261:17-21. 1989
  • Stimulation of phosphorylcholine turnover and diacylglycerol production in human polymorphonuclear leukocytes. Novel assay for phosphorylcholine..  260:909-913. 1989
  • Modulation of inositol phospholipid metabolism by polyamines..  256:125-130. 1988
  • Modification of the tandem reactive centres of human inter-alpha-trypsin inhibitor with butanedione and cis-dichlorodiammineplatinum(II)..  254:171-178. 1988
  • Determination of molecular mass of the aroid alternative oxidase by radiation-inactivation analysis..  252:73-77. 1988
  • Isolation, purification and characterization of an iron-binding protein from the horseshoe crab (Limulus polyphemus)..  252:151-157. 1988
  • GTP-mediated Ca2+ release in rough endoplasmic reticulum. Correlation with a GTP-sensitive increase in membrane permeability..  248:741-747. 1987
  • DNA fragmentation in permeabilized cells.  247:805-806. 1987
  • Purification of adenylosuccinate lyase from rat skeletal muscle by a novel affinity column. Stabilization of the enzyme, and effects of anions and fluoro analogues of the substrate..  246:263-269. 1987
  • Neomycin cannot be used as a selective inhibitor of inositol phospholipid hydrolysis in intact or semi-permeabilized human platelets. Aminoglycosides activate semi-permeabilized platelets.  243:815-819. 1987
  • Evidence that activation of acetyl-CoA carboxylase by insulin in adipocytes is mediated by a low-Mr effector and not by increased phosphorylation..  240:99-106. 1986
  • Further characterization of the platinum-reactive component of the alpha 2-macroglobulin-receptor recognition site..  238:217-225. 1986
  • Kinetics of substrate hydrolysis and inhibition by mipafox of paraoxon-preinhibited hen brain esterase activity..  236:503-507. 1986
  • Purification and characterization of human alpha 2-macroglobulin conformational variants by non-ideal high performance size-exclusion chromatography..  235:559-567. 1986
  • Both insulin and epidermal growth factor stimulate lipogenesis and acetyl-CoA carboxylase activity in isolated adipocytes. Importance of homogenization procedure in avoiding artefacts in acetyl-CoA carboxylase assay..  234:279-284. 1986
  • Translocation of phospholipid/Ca2+-dependent protein kinase in B-lymphocytes activated by phorbol ester or cross-linking of membrane immunoglobulin..  233:145-149. 1986
  • Covalent labelling of ligand binding sites of human placental S-adenosylhomocysteine hydrolase with 8-azido derivatives of adenosine and cyclic AMP..  232:643-650. 1985
  • Target size of neurotoxic esterase and acetylcholinesterase as determined by radiation inactivation..  231:789-792. 1985
  • S-Adenosylhomocysteine hydrolase from human placenta. Affinity purification and characterization..  230:43-52. 1985
  • Characterization of [3H]di-isopropyl phosphorofluoridate-binding proteins in hen brain. Rates of phosphorylation and sensitivity to neurotoxic and non-neurotoxic organophosphorus compounds..  228:537-544. 1985
  • Distinct sites on the G-actin molecule bind group-specific component and deoxyribonuclease I..  228:471-477. 1985
  • The role of calcium ions in the mechanism of action of alpha-adrenergic agonists in rat liver..  223:1-13. 1984
  • Glycogenolytic effects of the calcium ionophore A23187, but not of vasopressin or angiotensin, in foetal-rat hepatocytes..  220:441-445. 1984
  • The action of alpha-adrenergic agonists on plasma-membrane calcium fluxes in perfused rat liver..  220:43-50. 1984
  • The contribution of both extracellular and intracellular calcium to the action of alpha-adrenergic agonists in perfused rat liver..  220:35-42. 1984
  • An assessment of the calcium content of rat liver mitochondria in vivo..  218:415-420. 1984
  • Binding and uptake of [3H]adrenaline by perfused rat liver..  218:765-773. 1984
  • Evidence concerning the mechanism of insulin-receptor interaction and the structure of the insulin receptor from biological properties of covalently linked insulin dimers.  216:687-694. 1983
  • Noradrenaline treatment of rats stimulates H2O2 generation in liver mitochondria..  214:745-750. 1983
  • The effect of ionophore A23187 on calcium ion fluxes and alpha-adrenergic-agonist action in perfused rat liver..  214:405-412. 1983
  • Effect of acidosis on glutamine transport by isolated rat renal brush-border and basolateral-membrane vesicles..  212:713-720. 1983
  • Stimulation by alpha-adrenergic agonists of Ca2+ fluxes, mitochondrial oxidation and gluconeogenesis in perfused rat liver..  212:555-565. 1983
  • Clearance and binding of native and defucosylated lactoferrin..  212:249-257. 1983
  • Ligand binding, conformational change and plasma elimination of human, mouse and rat alpha-macroglobulin proteinase inhibitors..  209:99-105. 1983
  • Calcium ion fluxes induced by the action of alpha-adrenergic agonists in perfused rat liver..  208:619-630. 1982
  • Evidence for a direct effect of bacitracin on cell-mediated insulin degradation in isolated hepatocytes.  206:295-299. 1982
  • Purification and partial characterization of a thiol proteinase from the thermophilic fungus Humicola lanuginosa..  205:147-152. 1982
  • A procedure for the rapid preparation of mitochondria from rat liver..  204:731-735. 1982
  • Differential labelling of UDP-N-acetylglucosamine in Huntington's-chorea fibroblasts..  196:495-498. 1981
  • Identification of Limulus polyphemus haemocyanin messenger RNA..  196:653-656. 1981
  • Synthesis and secretion of alkaline phosphatasein vitrofrom first-trimester and term human placentas.  194:857-866. 1981
  • Glucagon stimulation of ruthenium red-insensitive calcium ion transport in developing rat liver..  194:541-549. 1981
  • Evidence for polymorphonuclear-leucocyte-derived proteinases in arthritic cartilage..  193:193-202. 1981
  • Huntington's-chorea fibroblasts. Cellular protein glycosylation..  190:711-719. 1980
  • Influence of starvation and clofibrate administration on oxidative phosphorylation by rat liver mitochondria..  190:191-198. 1980
  • Control of proteoglycan synthesis. Studies on the activation of synthesis observed during culture of articular cartilages..  188:119-130. 1980
  • Incorporation of methionine-derived methyl groups into sirohaem by Escherichia coli..  167:669-674. 1977
  • Cathepsin B1. A lysosomal enzyme that degrades native collagen..  137:387-398. 1974
  • Effect of steady illumination on the binding of carbon monoxide by carboxymethylated cytochrome c..  131:863-865. 1973
  • Isocoproporphyrin: nuclear-magnetic-resonance-and mass-spectral methods for the determination of porphyrin structure..  131:429-432. 1973
  • The induction of ornithine decarboxylase in cultured hepatoma cells..  130:78P-79P. 1972
  • The problem of hapten persistently bound to antibody.  116:151-153. 1970
  • Metabolism of nicotinamide and nicotinic acid in Corcyra cephalonica St..  74:355-359. 1960
  • Metabolism of nicotinamide and nicotinic acid in Neurospora crassa..  70:196-201. 1958
  • Effect of sulphanilamide on formation of sterols in Saccharomyces cerevisiae and Neurospora crassa..  69:53-56. 1958