Free Radical Biology and Medicine
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Publication Venue For
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Erratum to "Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite" [Free Radic. Biol. Med. 126 (2018) 379-392]..
129:611.
2018
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Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite..
126:379-392.
2018
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Redox and the circadian clock in plant immunity: A balancing act..
119:56-61.
2018
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Retraction notice to NAD(P)H:QUINONE OXIOREDUCTASE 1 PROTECTS LUNGS FROM OXIDANT-INDUCED EMPHYSEMA IN MICE [FRB 52/3 (2012) 705 - 715]..
113:580.
2017
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Methane ameliorates spinal cord ischemia-reperfusion injury in rats: Antioxidant, anti-inflammatory and anti-apoptotic activity mediated by Nrf2 activation.
103:69-86.
2017
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TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity..
102:260-273.
2017
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Extracellular superoxide dismutase is present in secretory vesicles of human neutrophils and released upon stimulation..
97:478-488.
2016
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A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis..
96:13-21.
2016
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Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling.
91:68-80.
2016
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Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling..
91:68-80.
2016
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Methane attenuates myocardial ischemia injury in rats through anti-oxidative, anti-apoptotic and anti-inflammatory actions.
90:1-11.
2016
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Anticancer therapeutic potential of Mn porphyrin/ascorbate system..
89:1231-1247.
2015
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Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease..
87:98-112.
2015
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A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics..
86:308-321.
2015
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Inorganic nitrite attenuates NADPH oxidase-derived superoxide generation in activated macrophages via a nitric oxide-dependent mechanism..
83:159-166.
2015
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Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells..
83:89-100.
2015
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Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis..
78:179-189.
2015
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A Comprehensive Study of the Catalase Activity of Different Classes of Experimental Therapeutics Commonly Used as Redox Modulators.
76:S85-S86.
2014
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Mitigation of Radiation-Mediated Suppression of Hippocampal Neurogenesis.
76:S97-S97.
2014
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Mn Porphyrin-Based SOD Mimic, MnTnHex-2-PyP5+ and Non-SOD Mimic, MnTBAP3- suppresed Rat Spinal Cord Ischemia/reperfusion Injury via NF-κB Pathways.
76:S95-S95.
2014
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Rational Design of New Cationic Mn Porphyrins and Evaluation of Their Therapeutic Potential.
76:S94-S94.
2014
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The Role of Ascorbate in Therapeutic Actions of Cationic Mn Porphyrin-Based SOD Mimics.
76:S94-S95.
2014
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Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury..
74:210-221.
2014
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Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment..
72:55-65.
2014
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Glutathionylated 4-hydroxy-2-(E)-alkenal enantiomers in rat organs and their contributions toward the disposal of 4-hydroxy-2-(E)-nonenal in rat liver..
70:78-85.
2014
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Redox properties of human hemoglobin in complex with fractionated dimeric and polymeric human haptoglobin..
69:265-277.
2014
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Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death..
68:302-314.
2014
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Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons..
68:220-233.
2014
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Mechanistic Considerations of the Therapeutic Effects of Mn Porphyrins, Commonly Regarded as SOD Mimics, in Anticancer Therapy: Lessons from Brain and Lymphoma Studies.
65:S120-S121.
2013
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Nox1 Endocytosis and Activation Are Regulated by Intracellular Hydrophobic Motifs.
65:S83-S83.
2013
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Pharmacokinetics, Brain Hippocampus and Cortex, and Mitochondrial Accumulation of a New Generation of Lipophilic Redox-Active Therapeutic, Mn(III) Meso Tetrakis(N-n-butoxyethylpyridinium-2-yl)porphyrin, MnTnBuOE-2-PyP5+, in Comparison with its Ethyl and N-hexyl Analogs, MnTE-2-PyP5+ and MnTnHex-2-PyP5+.
65:S132-S132.
2013
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Oxidative damage to macromolecules in human Parkinson disease and the rotenone model..
62:111-120.
2013
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The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies..
60:157-167.
2013
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4-Hydroxy-2(E)-nonenal (HNE) catabolism and formation of HNE adducts are modulated by β oxidation of fatty acids in the isolated rat heart..
58:35-44.
2013
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Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+..
58:73-80.
2013
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Redox regulation of mitochondrial biogenesis..
53:2043-2053.
2012
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Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice..
53:1584-1594.
2012
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Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions..
53:1317-1326.
2012
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Is the flavohemoglobin a nitric oxide dioxygenase?.
53:1209-1210.
2012
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Response to "is flavohemoglobin a nitric oxide dioxygenase?".
53:1211-1212.
2012
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Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina..
53:64-71.
2012
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A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity..
52:1828-1834.
2012
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Off-target thiol alkylation by the NADPH oxidase inhibitor 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine (VAS2870)..
52:1897-1902.
2012
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Protection from nitrosative stress: a central role for microbial flavohemoglobin..
52:1620-1633.
2012
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The role of death effector domain-containing proteins in acute oxidative cell injury in hepatocytes..
52:1911-1917.
2012
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Manganese porphyrin, MnTE-2-PyP5+, Acts as a pro-oxidant to potentiate glucocorticoid-induced apoptosis in lymphoma cells..
52:1272-1284.
2012
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Dietary regulation of catabolic disposal of 4-hydroxynonenal analogs in rat liver..
52:1043-1053.
2012
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Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis..
52:462-472.
2012
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Mitochondrial Acetylomic Analysis in a Mouse Model of Alcohol-Induced Liver Injury Utilizing SIRT3 Knockout Mice.
51:S19-S20.
2011
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Erratum: Inhibition of nitric oxide synthase by cobalamins and cobinamides (Free Radical Biology & Medicine (2009) 46 (1626-1632)).
51:1471.
2011
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Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics..
51:1035-1053.
2011
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Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death..
50:624-632.
2011
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Plasma nitrite flux predicts exercise performance in peripheral arterial disease after 3months of exercise training..
49:1138-1144.
2010
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Transport rather than diffusion-dependent route for nitric oxide gas activity in alveolar epithelium..
49:294-300.
2010
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Corrigendum to "Radio-protective effects of manganese-containing superoxide dismutase mimics on ataxia telangiectasia cells" [Free Radic. Biol. Med. 47/3 (2009) 250-260] (DOI:10.1016/j.freeradbiomed.2009.04.018).
47:1234.
2009
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Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor..
47:992-1004.
2009
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Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells..
47:250-260.
2009
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Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins..
47:72-78.
2009
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Detection of protein S-nitrosylation with the biotin-switch technique..
46:119-126.
2009
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Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways..
46:212-219.
2009
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Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy..
46:192-201.
2009
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Oxidative stress in diseases of the human cornea..
45:1047-1055.
2008
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Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 mice..
45:943-949.
2008
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Carbon monoxide, reactive oxygen signaling, and oxidative stress.
45:562-569.
2008
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Carbon monoxide, reactive oxygen signaling, and oxidative stress..
45:562-569.
2008
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Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier..
45:201-210.
2008
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Redox-based regulation of signal transduction: principles, pitfalls, and promises..
45:1-17.
2008
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The chemical biology of nitric oxide: implications in cellular signaling..
45:18-31.
2008
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Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection..
44:982-989.
2008
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Keap1 modification and nuclear accumulation in response to S-nitrosocysteine..
44:692-698.
2008
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Identification of JWA as a novel functional gene responsive to environmental oxidative stress induced by benzo[a]pyrene and hydrogen peroxide..
42:1704-1714.
2007
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Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion..
42:1571-1578.
2007
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Regulation of MUC5AC expression by NAD(P)H:quinone oxidoreductase 1..
42:1398-1408.
2007
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Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria..
42:1193-1200.
2007
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Metabolic capacity regulates iron homeostasis in endothelial cells..
41:1662-1669.
2006
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Modification of cysteine 111 in human Cu,Zn-superoxide dismutase..
41:1837-1846.
2006
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Total nitrogen oxide following exercise testing reflects endothelial function and discriminates health status..
41:740-747.
2006
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Reduction of manganese porphyrins by flavoenzymes and submitochondrial particles: a catalytic cycle for the reduction of peroxynitrite..
41:503-512.
2006
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Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition..
40:1332-1339.
2006
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Glutathione regulates susceptibility to oxidant-induced mitochondrial DNA damage in human lymphocytes..
40:1220-1226.
2006
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Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme..
40:1419-1429.
2006
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Differential regulation of c-jun and CREB by acrolein and 4-hydroxynonenal..
40:21-34.
2006
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Regional and whole-body markers of nitric oxide production following hyperemic stimuli..
38:1164-1169.
2005
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Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice..
38:729-736.
2005
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Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading..
38:719-728.
2005
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Carbon monoxide actuates O(2)-limited heme degradation in the rat brain..
37:1802-1812.
2004
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Complementation of SOD-deficient Escherichia coli by manganese porphyrin mimics of superoxide dismutase activity..
37:401-410.
2004
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S-Nitrosohemoglobin: an allosteric mediator of NO group function in mammalian vasculature..
37:442-453.
2004
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Tetrahydrobiopterin rapidly reduces the SOD mimic Mn(III) ortho-tetrakis(N-ethylpyridinium-2-yl)porphyrin..
37:367-374.
2004
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Proteomic identification of specific oxidized proteins in ApoE-knockout mice: relevance to Alzheimer's disease..
36:1155-1162.
2004
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The iron cycle and oxidative stress in the lung..
36:850-857.
2004
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Cupric-amyloid beta peptide complex stimulates oxidation of ascorbate and generation of hydroxyl radical..
36:340-347.
2004
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Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factors..
35:1158-1167.
2003
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Peroxynitrite flux-mediated LDL oxidation is inhibited by manganese porphyrins in the presence of uric acid..
35:1293-1300.
2003
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Vanadium-induced STAT-1 activation in lung myofibroblasts requires H2O2 and P38 MAP kinase..
35:845-855.
2003
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Redox regulation of neuronal migration in a Down Syndrome model..
35:566-575.
2003
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Urinary F2-isoprostanes in young healthy children at risk for type 1 diabetes mellitus.
35:551-557.
2003
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Hemodynamic effects of metalloporphyrin catalytic antioxidants: structure-activity relationships and species specificity..
33:1657-1669.
2002
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A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke..
33:1141-1152.
2002
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Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia..
33:947-961.
2002
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A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury..
33:857-863.
2002
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Apolipoprotein E isoform mediated regulation of nitric oxide release..
32:1071-1075.
2002
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The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression..
32:1116-1122.
2002
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Rapid mtDNA deletion by oxidants in rat liver mitochondria after hemin exposure..
32:246-256.
2002
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AEOL 10150, a metalloporphyrin catalytic antioxidant, reduces injury from focal ischemia in the rat and mouse.
33:S126-S127.
2002
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Development of potent Mn(III) N-alkylpyridylporphyrin-based catalytic antioxidants for treating ischemic/raumatic injuries of central nervous system..
33:S125-S126.
2002
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Development of potent Mn(III) N-alkylpyridylporphyrin-based catalytic antioxidants for treating ischemic/traumatic injuries of central nervous system..
33:S236-S237.
2002
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Effects of metalloporphyrin catalytic antioxidant AEOL 10113 on radiation-induced lung injury.
33:S239-S239.
2002
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Altered expression of extracellular superoxide dismutase in mouse lung after bleomycin treatment..
31:1198-1207.
2001
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Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine..
31:175-180.
2001
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Activation of NO electrodes.
31:S76-S76.
2001
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Biliverdin is preorganized for dimeric metal complex formation, therefore for its antioxidant role in vitro.
31:S20-S20.
2001
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Changes in protein expression after a superoxide dismutase mimetic in stroke..
31:S132-S132.
2001
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Effects of metalloporphyrin catalytic antioxidants on rodent focal ischemic brain damage.
31:S134-S134.
2001
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Hepatic mitochondrial DNA damage and oxidative stress by lipopolysaccharide (LPS).
31:S90-S90.
2001
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Iron uptake in bronchial epithelial cells requires O2-transport by anion exchange protein 2.
31:S18-S18.
2001
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Mitochondrial DNA deletion decreases cytochrome oxidase subunit IV.
31:S84-S84.
2001
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Nitric oxide and peroxynitrite inhibits NADPH oxidase in human vascular smooth muscle cells..
31:S71-S71.
2001
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Nitric oxide in the respiratory cycle in human health and disease.
31:S71-S71.
2001
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Species-specific hemodynamic effects of metalloporphyrin SOD mimetics.
31:S96-S96.
2001
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Superoxide dismutase (SOD) mimetics in radiation therapy.
31:S128-S128.
2001
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The nitric oxide synthase inhibitor NG-nitro-L-arginine decreases defibrillation induced free radical generation.
31:S71-S71.
2001
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Manganese-porphyrin reactions with lipids and lipoproteins..
28:1017-1029.
2000
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Oxidative stress and adenine nucleotide control of mitochondrial permeability transition..
28:251-260.
2000
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Metalloporphyrins are potent inhibitors of lipid peroxidation..
26:730-736.
1999
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Porphyrin-based SOD mimics. Electrospray mass spectroscopy of Mn(III) and Fe(III) isomeric tetrakis-(N-alkylpyridyl) porphyrins..
27:S18-S18.
1999
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Thermodynamic linkage relationships in S-nitrosohemoglobin: Oxygen binding and vasoactivity.
27:S81-S81.
1999
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Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro..
24:863-868.
1998
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Nitration of membrane proteins in lungs after normoxic ischemia-reperfusion..
25:S61-S61.
1998
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Nitrosylation of blood hemoglobin and renal nonheme proteins in autoimmune MRL-lpr/lpr mice..
24:191-196.
1998
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Production of hydroxyl radical in the hippocampus after CO hypoxia or hypoxic hypoxia in the rat..
22:725-732.
1997
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Location-dependent artifact for no measurement using multiwell plates..
20:361-363.
1996
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Purification and characterization of the Cu,Zn SOD from Escherichia coli..
21:117-121.
1996
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Hydroxyl radical production in the brain after CO hypoxia in rats..
18:603-609.
1995
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Antioxidant and cytotoxic tocopheryl quinones in normal and cancer cells.
18:963-976.
1995
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Letter to the editor.
8:488-489.
1990
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Hyperoxia during reperfusion is a factor in reperfusion injury..
6:61-62.
1989
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The action of hydrogen peroxide on paired pulse and long-term potentiation in the hippocampus..
7:3-8.
1989
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Circulating EGF-Like Ligands in Obesity Increase Neointimal Formation through Upregulation of NADPH Oxidase 1
2016
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Redox Regulated Mitophagy in the Lung during Murine Sepsis
2013
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Comprehensive Pharmacokinetic Studies and Biodistribution of Two Cationic Mn Porphyrin-Based Catalysts, MnTE-2-PyP5+ and MnTnHex-2-PyP5+: Plasma and Organ Oral Availability, Mitochondrial, Cytosolic, Whole Brain, Hippocampus and Cortex Distribution
2012
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Nox1 NADPH Oxidase is Necessary for Late, but not Early, Ischemic Preconditioning against Myocardial Infarction in Mice
2012
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Nox1 Phosphorylation in Cardiovascular Disease
2012
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Quantification of Tetrahydrobiopterin (BH4), Dihydrobiopterin (BH2) and Biopterin (BP) in Mouse Brain and Intestines After Ischemic Injury by Liquid Chromatography-Electrospray Tandem Mass Spectrometry (LC-ESI-MS/MS)
2012
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A Breakthrough in the Development of SOD Mimics/Cellular Redox Modulators: a Superior Mn porphyrin, MnTnBuOE-2-PyP5+ With Finely Tuned Properties
2011
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Dual Antioxidant Activity of Boronate-Based Prochelators: Scavenging Peroxynitrite and Metal Ion Chelation
2011
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Heme Oxygenase 1 Promotes Murine Stem Cell Differentiation into Beating Cardiomyocytes
2011
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Leptin is Key To Macrophage-Dependent Free Radical Formation in Ccl4-Induced Exacerbation of Steatohepatitis of Obesity
2011
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Lipophilic Mn Porphyrins in the Treatment of Brain Tumors
2011
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PGC-1α and the Mitochondrial Antioxidant Response during Sepsis
2011
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Deconstructing Mitochondria: Co-localization of HO-1 and LC3II Mitophagy Protein in Liver Mitochondria during Oxidative Stress and Sepsis
2010
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Increased Heme Degradation and Impaired Deformability of Red Blood Cells in Sickle Cell Disease and Anemia
2010
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Inhibition of EGFR Signaling Induces Metabolic Oxidative Stress in Human Head and Neck Cancer Cells
2010
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Structural Modification Diminishes Toxicity of Lipophilic Longer Mn(III) N-alkylpyridyl porphyrin-based Powerful SOD Mimics: Synthesis, Characterization and SOD-deficient E. coli and S. cerevisiae studies
2010
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The Beneficial Effects of One Year Pomegranate Juice Consumption on Traditional and Nontraditional Risk Factors for Cardiovascular Diseases
2010
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The in vitro Cytotoxic Effects of Mn(III) Alkylpyridylporphyrin/ascorbate system on Four Tumor Cell Lines
2009
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Oral Availability of Mnte-2-Pyp(5+), a Potent Antioxidant and Cellular Redox Modulator
2008
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Erythropoietin promotes cardiac mitochondrial biogenesis through Akt activation
2007
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Heme oxygenase-1 supports mitochondrial function and protects against doxorubicin toxicity via the Pi3K/Akt pathway
2007
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Nitric oxide and toll-like receptor 4 are required for cardiac mitochondrial biogenesis after endotoxemia
2007
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Skeletal muscle mitochondrial biogenesis induced by carbon monoxide
2007
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Carbon monoxide protects against mitochondrial damage in doxorubicin-induced myocardial dysfunction
2006
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Extracellular superoxide regulates hypoxia-induced Egr-1 and tissue factor expression and promotes hypoxic pulmonary vascular remodeling
2006
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Mitochondrial biogenesis in sepsis: a role for inducible nitric oxide synthase
2006
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NOX4 mediates thrombin signaling in endothelial cells
2006
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Oxidation and CBS in neural derived cells
2006
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New Mn(III) porphyrins with high superoxide disproportionating ability
2005
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Transient carbon monoxide exposure induces cardiac mitochondriobiogenic response.
2005
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Ec-SOD overexpression reduces blood-spinal cord barrier permeability and inflammatory cell infiltration, but does not improve outcome from spinal cord compression injury in the mouse
2004
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Improving bioavailibility of SOD mimics
2004
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MNTE-2-PYP5+ enhances tumor radiosensitivity by sensitizing tumor vasculature
2004
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Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused, apolipoprotein E-deficient mice
2004
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Mn(III) meso tetrakis(N,N '-diethylimidazolium-2-yl)porphyrin (AEOL-10150) offers protection in mouse model of spinal cord injury
2003
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Recent advances in the synthesis and characterization of MN water-soluble porphyrin-based catalytic antioxidants
2003
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The role of antioxidant-1 in extracellular superoxide dismutase function
2003
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Mn(III) meso-tetrakis(ortho N-ethyl-pyridyl)porphyrin, MnTE-2-PyP (AEOL-10113) offers protection in mouse spinal cord injury model
2002
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Cupric-amyloid b peptide complexes stimulate oxidation of ascorbate and generation of OH- radials
2001
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The chemistry of nitroxyl (HNO) and implications in various therapeutic applications.
2001
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Reactive oxygen species mediate neutrophil elastase - Induced MUC 5AC mRNA expression.
1998