Cellular Signalling

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  Publication Venue For

  • The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages..  20:1459-1470. 2008
  • Endogenous RGS proteins attenuate Galpha(i)-mediated lysophosphatidic acid signaling pathways in ovarian cancer cells..  20:381-389. 2008
  • Interaction between TCL1 and Epac1 in the activation of Akt kinases in plasma membranes and nuclei of 8-CPT-2-O-Me-cAMP-stimulated macrophages..  20:130-138. 2008
  • GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin..  19:1733-1744. 2007
  • Abi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosis..  19:1602-1609. 2007
  • Dual kinase-mediated regulation of PITK by CaMKII and GSK3..  19:593-599. 2007
  • Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms..  19:251-260. 2007
  • PITK, a PP1 targeting subunit that modulates the phosphorylation of the transcriptional regulator hnRNP K..  18:1769-1778. 2006
  • ZIP kinase, a key regulator of myosin protein phosphatase 1..  17:1313-1322. 2005
  • PKA-mediated phosphorylation of the beta1-adrenergic receptor promotes Gs/Gi switching..  16:1397-1403. 2004
  • Differences between AGAP1, ASAP1 and Arf GAP1 in substrate recognition: interaction with the N-terminus of Arf1..  16:1033-1044. 2004
  • The GIT/PIX complex: an oligomeric assembly of GIT family ARF GTPase-activating proteins and PIX family Rac1/Cdc42 guanine nucleotide exchange factors..  16:1001-1011. 2004
  • A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates alpha2M*-induced signalling..  16:929-938. 2004
  • Activin induces hepatocyte cell growth arrest through induction of the cyclin-dependent kinase inhibitor p15INK4B and Sp1..  16:693-701. 2004
  • Potentiation of signal transduction mitogenesis and cellular proliferation upon binding of receptor-recognized forms of alpha2-macroglobulin to 1-LN prostate cancer cells..  16:487-496. 2004
  • Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts..  16:313-321. 2004
  • Induction of mitogenic signalling in the 1LN prostate cell line on exposure to submicromolar concentrations of cadmium+..  15:1059-1070. 2003
  • Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms..  14:327-340. 2002
  • Induction of cyclooxygenase-2 synthesis by ligation of the macrophage alpha(2)-macroglobulin signalling receptor..  13:801-808. 2001
  • Beta-Arrestins: new roles in regulating heptahelical receptors' functions..  13:683-689. 2001
  • Beta-Arrestins: new roles in regulating heptahelical receptors' functions..  13:683-689. 2001
  • Potentiation of calcium levels by extracellular arachidonic acid in nuclei isolated from macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin..  12:99-104. 2000
  • Ligation of the alpha2M signalling receptor elevates the levels of p21Ras-GTP in macrophages..  10:441-445. 1998
  • The role of prenylation in G-protein assembly and function..  8:433-437. 1996
  • Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C..  7:171-184. 1995
  • Overexpression of pp60c-src is associated with altered regulation of adenylyl cyclase..  4:531-541. 1992
  • Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein..  3:547-557. 1991
  • Regulation of protein kinases by pseudosubstrate prototopes..  1:303-311. 1989