Oncogene

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  Publication Venue For

  • The emerging roles of Gα12/13 proteins on the hallmarks of cancer in solid tumors..  41:147-158. 2022
  • TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function.  36:4336-4348. 2017
  • Cell cycle-coupled expansion of AR activity promotes cancer progression.  36:1655-1668. 2017
  • Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin..  36:1698-1706. 2017
  • The human oncoprotein and chromatin architectural factor DEK counteracts DNA replication stress..  34:4270-4277. 2015
  • Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death..  34:3264-3272. 2015
  • Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling.  33:3970-3979. 2014
  • Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death 2014
  • Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms..  32:1316-1329. 2013
  • Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes.  32:5388-5396. 2013
  • Lack of p53 induction in fish cells by model chemotherapeutics (Oncogene (2006) 25, (2004-2010) DOI: 10.1038/onc.2009.8).  28:1400. 2009
  • Interferon regulatory factor-1-induced apoptosis mediated by a ligand-independent fas-associated death domain pathway in breast cancer cells..  26:6420-6430. 2007
  • Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases..  26:4084-4094. 2007
  • RalA regulates vascular endothelial growth factor-C (VEGF-C) synthesis in prostate cancer cells during androgen ablation..  26:1731-1738. 2007
  • A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation..  26:1188-1200. 2007
  • Genetic induction of tumorigenesis in swine..  26:1038-1045. 2007
  • Flying at the head of the pack: Wnt biology in Drosophila..  25:7442-7449. 2006
  • Apoptotic DNA fragmentation factor maintains chromosome stability in a P53-independent manner..  25:5370-5376. 2006
  • A novel T-77C polymorphism in DNA repair gene XRCC1 contributes to diminished promoter activity and increased risk of non-small cell lung cancer..  25:3613-3620. 2006
  • Lack of p53 induction in fish cells by model chemotherapeutics..  25:2004-2010. 2006
  • Merlin facilitates ubiquitination and degradation of transactivation-responsive RNA-binding protein..  25:1143-1152. 2006
  • IGF2 is critical for tumorigenesis by synovial sarcoma oncoprotein SYT-SSX1..  25:1042-1052. 2006
  • Role of elongin-binding domain of von Hippel Lindau gene product on HuR-mediated VPF/VEGF mRNA stability in renal cell carcinoma..  24:7850-7858. 2005
  • Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation..  24:6249-6255. 2005
  • Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma..  24:6441-6449. 2005
  • Upregulation of VEGF-C by androgen depletion: the involvement of IGF-IR-FOXO pathway..  24:5510-5520. 2005
  • Erratum: The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-κB and c-Myc in pancreatic cancer cells (Oncogene (2004) 23 (8571-8580) DOI: 10.1038/sj.onc.1207902).  24:4320. 2005
  • Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome..  24:3847-3852. 2005
  • Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer..  24:2705-2714. 2005
  • Definition and characterization of a region of 1p36.3 consistently deleted in neuroblastoma..  24:2684-2694. 2005
  • Plasminogen activator inhibitor-1 (PAI-1) modifies the formation of aggressive fibromatosis (desmoid tumor)..  24:1615-1624. 2005
  • Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes..  23:9120-9128. 2004
  • The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells..  23:8571-8580. 2004
  • Protein patterns and proteins that identify subtypes of glioblastoma multiforme..  23:6806-6814. 2004
  • The Ras-related protein AGS1/RASD1 suppresses cell growth..  23:5858-5863. 2004
  • Disruption of the Rad9/Rad1/Hus1 (9-1-1) complex leads to checkpoint signaling and replication defects..  23:5586-5593. 2004
  • Multiple cell-type-specific elements regulate Myc protein stability..  23:3863-3871. 2004
  • Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity..  23:3851-3862. 2004
  • The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase..  23:3749-3756. 2004
  • Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis..  23:3550-3560. 2004
  • Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation..  23:3122-3127. 2004
  • Enhanced malignant tumorigenesis in Cdk4 transgenic mice..  23:1863-1873. 2004
  • Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors..  23:654-664. 2004
  • Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients..  23:605-611. 2004
  • PI3K/Akt and apoptosis: size matters..  22:8983-8998. 2003
  • A decade of caspases..  22:8543-8567. 2003
  • Association of a functional tandem repeats in the downstream of human telomerase gene and lung cancer..  22:7123-7129. 2003
  • Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor)..  22:6873-6882. 2003
  • Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells..  22:4509-4516. 2003
  • Beta-catenin expression in Dupuytren's disease: potential role for cell-matrix interactions in modulating beta-catenin levels in vivo and in vitro..  22:3680-3684. 2003
  • Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors..  22:2812-2822. 2003
  • Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin..  22:1955-1964. 2003
  • A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis..  22:1771-1782. 2003
  • Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis..  22:1365-1370. 2003
  • Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis..  22:319-329. 2003
  • Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cells..  21:8749-8758. 2002
  • The biology of chronic myelogenous leukemia:mouse models and cell adhesion..  21:8612-8628. 2002
  • Mutational analysis defines a minimum level of telomerase activity required for tumourigenic growth of human cells..  21:7121-7125. 2002
  • Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines..  21:6549-6556. 2002
  • The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis..  21:6510-6519. 2002
  • The DNA repair protein, O(6)-methylguanine-DNA methyltransferase is a proteolytic target for the E6 human papillomavirus oncoprotein..  21:5940-5945. 2002
  • Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1.  21:5609-5618. 2002
  • SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing disc..  21:4812-4821. 2002
  • Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA..  21:878-889. 2002
  • Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas..  21:921-928. 2002
  • Over-expression of insulin-like growth factor binding protein-related protein-1(IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumor growth by a delay in G1 and cyclin A associated apoptosis.  21:140-147. 2002
  • A novel human cancer culture model for the study of prostate cancer..  20:8036-8041. 2001
  • Transcription of the RelB gene is regulated by NF-kappaB..  20:7722-7733. 2001
  • Expanding the role of NHERF, a PDZ-domain containing protein adapter, to growth regulation..  20:6309-6314. 2001
  • Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells..  20:5789-5798. 2001
  • Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells..  20:3665-3673. 2001
  • Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells..  20:3751-3756. 2001
  • Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer..  20:3348-3353. 2001
  • New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades..  20:1532-1539. 2001
  • RB regulates transcription of the p21/WAF1/CIP1 gene..  20:962-971. 2001
  • Cyclooxygenase-two (COX-2) modulates proliferation in aggressive fibromatosis (desmoid tumor)..  20:451-460. 2001
  • A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer..  19:5747-5754. 2000
  • Bcl-2 accelerates multistep prostate carcinogenesis in vivo..  19:5251-5258. 2000
  • The human myoepithelial cell displays a multifaceted anti-angiogenic phenotype..  19:3449-3459. 2000
  • The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo..  19:2404-2412. 2000
  • Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability..  19:2249-2256. 2000
  • Ionizing radiation activates the ATM kinase throughout the cell cycle..  19:1386-1391. 2000
  • Inhibition of growth of human malignant glioblastoma in nude mice by antagonists of bombesin/gastrin-releasing peptide..  18:7168-7173. 1999
  • Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor)..  18:6615-6620. 1999
  • Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites..  18:6252-6261. 1999
  • Isolation and initial characterization of the BRCA2 promoter..  18:6000-6012. 1999
  • Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA..  18:4554-4563. 1999
  • Calcitonin driven v-Ha-ras induces multilineage pulmonary epithelial hyperplasias and neoplasms..  18:4336-4347. 1999
  • Telomerase activity in ductal carcinoma in situ and invasive breast cancer..  18:3407-3414. 1999
  • Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation..  18:2872-2882. 1999
  • Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia..  18:79-85. 1999
  • Molecular and immunological analysis of genetic prostate specific antigen (PSA) vaccine..  17:3125-3135. 1998
  • Genomic structure of the gene for the SH2 and pleckstrin homology domain-containing protein GRB10 and evaluation of its role in Hirschsprung disease..  17:3065-3070. 1998
  • Evidence for a role of Met-HGF/SF during Ras-mediated tumorigenesis/metastasis..  17:2019-2025. 1998
  • RET cooperates with RB/p53 inactivation in a somatic multi-step model for murine thyroid cancer..  17:1625-1628. 1998
  • Decreased fibronectin expression in Met/HGF-mediated tumorigenesis..  17:1179-1183. 1998
  • Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53..  17:1089-1096. 1998
  • Co-amplification of a novel cyclophilin-like gene (PPIE) with L-myc in small cell lung cancer cell lines..  17:1019-1026. 1998
  • Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression..  16:3087-3095. 1998
  • Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice..  16:2333-2343. 1998
  • Type I interferon induction of the Cdk-inhibitor p21WAF1 is accompanied by ordered G1 arrest, differentiation and apoptosis of the Daudi B-cell line..  16:1885-1890. 1998
  • Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein..  16:1299-1308. 1998
  • Increased transversions in a novel mutator colon cancer cell line..  16:1125-1130. 1998
  • Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase..  16:1217-1222. 1998
  • Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis..  16:957-966. 1998
  • Expression of v-Ha-ras driven by the calcitonin/calcitonin gene-related peptide promoter: a novel transgenic murine model for medullary thyroid carcinoma..  16:167-177. 1998
  • Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer..  15:3059-3065. 1997
  • Influence of ATM function on telomere metabolism..  15:2659-2665. 1997
  • The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells..  15:2333-2342. 1997
  • Rapamycin and p53 act on different pathways to induce G1 arrest in mammalian cells..  15:1635-1642. 1997
  • A region of interstitial 17q25 allelic loss in ovarian tumors coincides with a defined region of loss in breast tumors..  14:1991-1994. 1997
  • A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-beta1..  14:1679-1685. 1997
  • Abrogation of p53 function by HPV16 E6 gene delays apoptosis and enhances mutagenesis but does not alter radiosensitivity in TK6 human lymphoblast cells..  14:1661-1667. 1997
  • BRCA1 expression is not directly responsive to estrogen..  14:115-121. 1997
  • The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway..  13:2589-2594. 1996
  • Chromosome end-to-end associations and telomerase activity during cancer progression in human cells after treatment with alpha-particles simulating radon progeny..  13:1423-1430. 1996
  • Dominance of wild-type p53-mediated transcriptional activation in breast epithelial cells..  13:1315-1322. 1996
  • HER-2/c-erbB2 is phosphorylated by calmodulin-dependent protein kinase II on a single site in the cytoplasmic tail at threonine-1172..  12:2725-2730. 1996
  • Molecular biology of normal development, malignancy and its suppression..  12:2247-2250. 1996
  • Deletions and rearrangements inactivate the p16INK4 gene in human glioma cells..  12:2029-2034. 1996
  • M6P/IGF2 receptor: a candidate breast tumor suppressor gene..  12:2003-2009. 1996
  • Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability..  12:1425-1432. 1996
  • Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines..  11:1885-1892. 1995
  • Mechanism of inactivation of CDKN2 and MTS2 in non-small cell lung cancer and association with advanced stage..  11:1843-1851. 1995
  • Mutagenic analysis of functional domains of the mos proto-oncogene and identification of the sites important for MAPK activation and DNA binding..  11:1447-1457. 1995
  • Abrogation of p53 function by transfection of HPV16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation..  10:2403-2408. 1995
  • Mechanism of inactivation of CDKN2 and MTS2 in non-small cell lung cancer and association with advanced stage.  11:1843-1851. 1995
  • Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors..  9:1321-1326. 1994
  • Activation of fibroblast growth factor (FGF) receptors by recombinant human FGF-5..  8:1311-1316. 1993
  • Analysis of the neurofibromatosis type 1 (NF1) GAP-related domain by site-directed mutagenesis..  8:761-769. 1993
  • Cloning and structural analysis of the human c-kit gene..  7:1259-1266. 1992
  • Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines..  7:127-133. 1992
  • The 5' non-coding region of the BCR/ABL oncogene augments its ability to stimulate the growth of immature lymphoid cells..  6:1299-1306. 1991
  • Preneoplastic lesions induced by myc and src oncogenes in a heterotopic rat colon..  6:303-309. 1991
  • Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3..  6:3-9. 1991
  • Baculovirus expression of functional P210 BCR-ABL oncogene product..  4:759-766. 1989
  • P150c-abl is detected in mouse male germ cells by an in vitro kinase assay and is associated with stage-specific phosphoproteins in haploid cells..  4:685-690. 1989
  • Erratum: Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome (Oncogene (2005) 24 (3847-3852) DOI:10.1038/sj.onc.1208518).  26:6684. 2007
  • Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25..  10:2243-2246. 1995