Chemistry & Biology

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  Publication Venue For

  • Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70.  21:1648-1659. 2014
  • Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70..  21:1648-1659. 2014
  • Emergent dynamics from quorum eavesdropping..  21:1601-1602. 2014
  • Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection..  21:977-987. 2014
  • Probing the coagulation pathway with aptamers identifies combinations that synergistically inhibit blood clot formation..  21:935-944. 2014
  • Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington’s Disease Models.  20:742-742. 2013
  • TR-FRET-based duplex immunoassay reveals an inverse correlation of soluble and aggregated mutant huntingtin in huntington's disease..  19:264-275. 2012
  • Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90..  17:686-694. 2010
  • Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models.  17:1189-1200. 2010
  • Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries..  15:969-978. 2008
  • Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer..  15:675-682. 2008
  • Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis..  14:291-302. 2007
  • Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44..  13:973-983. 2006
  • Peptide-PEG amphiphiles as cytophobic coatings for mammalian and bacterial cells..  13:695-700. 2006
  • Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications..  13:563-567. 2006
  • Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90..  11:787-797. 2004
  • A suppression strategy for antibiotic discovery.  11:1330-1332. 2004
  • Profiling natural product biosynthesis.  11:290-291. 2004
  • A new H/D exchange- and mass spectrometry-based method for thermodynamic analysis of protein-DNA interactions..  10:1205-1213. 2003
  • Functional Analysis of the Lipoglycodepsipeptide Antibiotic Ramoplanin.  9:897-906. 2002
  • Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: Attributes of catalytic efficiency, stereoselectivity and regulation with implications for function.  5:489-504. 1998
  • Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters?.  4:711-715. 1997
  • Copper-binding motifs in catalysis, transport, detoxification and signaling.  4:549-560. 1997
  • RNA surfaces as functional mimetics of proteins..  3:505-513. 1996
  • Biochemical mass spectrometry: Worth the weight?.  3:707-715. 1996
  • Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis.  3:817-825. 1996
  • Revising messages traveling along the cellular information superhighway..  2:249-253. 1995