Proc Natl Acad Sci U S A

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  Publication Venue For

  • Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models. 2020
  • Centromere scission drives chromosome shuffling and reproductive isolation. 2020
  • Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics..  117:4109-4116. 2020
  • Widespread organ tolerance to Xist loss and X reactivation except under chronic stress in the gut..  117:4262-4272. 2020
  • Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion..  117:3535-3542. 2020
  • A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes..  117:563-572. 2020
  • Translational implications of the anatomical nonequivalence of functionally equivalent cholinergic circuit motifs. 2019
  • Photoreceptor disc membranes are formed through an Arp2/3-dependent lamellipodium-like mechanism. 2019
  • Increased stiffness and flow resistance of the inner wall of Schlemm's canal in glaucomatous human eyes. 2019
  • Ca2+/CaM interaction with voltage-gated Na+ channels. 2019
  • Contribution of proteasome-catalyzed peptide cis-splicing to viral targeting by CD8+ T cells in HIV-1 infection..  116:24748-24759. 2019
  • Deletions associated with stabilization of the Top1 cleavage complex in yeast are products of the nonhomologous end-joining pathway..  116:22683-22691. 2019
  • Creating a neuroprosthesis for active tactile exploration of textures..  116:21821-21827. 2019
  • Genetic variation of DNA methyltransferase-3A contributes to protection against persistent MRSA bacteremia in patients..  116:20087-20096. 2019
  • Molecular control limiting sensitivity of sweet taste neurons in Drosophila..  116:20158-20168. 2019
  • Neurodevelopmental mutation of giant ankyrin-G disrupts a core mechanism for axon initial segment assembly..  116:19717-19726. 2019
  • Neutrophils promote tumor resistance to radiation therapy..  116:18584-18589. 2019
  • Epithelial delamination is protective during pharmaceutical-induced enteropathy..  116:16961-16970. 2019
  • Functional selection of protease inhibitory antibodies..  116:16314-16319. 2019
  • Three-dimensional structure of the basketweave Z-band in midshipman fish sonic muscle..  116:15534-15539. 2019
  • βII-spectrin promotes mouse brain connectivity through stabilizing axonal plasma membranes and enabling axonal organelle transport..  116:15686-15695. 2019
  • ANK2 autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity..  116:15262-15271. 2019
  • The combination of TPL2 knockdown and TNFα causes synthetic lethality via caspase-8 activation in human carcinoma cell lines..  116:14039-14048. 2019
  • PRCD is essential for high-fidelity photoreceptor disc formation..  116:13087-13096. 2019
  • Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk..  116:11370-11379. 2019
  • Predicting clinical outcome of therapy-resistant prostate cancer..  116:11090-11092. 2019
  • Genetic variation across the human olfactory receptor repertoire alters odor perception..  116:9475-9480. 2019
  • Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy..  116:6308-6312. 2019
  • Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development..  116:5570-5575. 2019
  • Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice..  116:3703-3711. 2019
  • TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension..  116:1992-1997. 2019
  • ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia..  116:1603-1612. 2019
  • In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model..  116:1714-1722. 2019
  • Toward understanding cancer stem cell heterogeneity in the tumor microenvironment..  116:148-157. 2019
  • Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4..  115:12265-12270. 2018
  • Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory..  115:E11111-E11119. 2018
  • Pervasive tertiary structure in the dengue virus RNA genome..  115:11513-11518. 2018
  • A potential solution for eliminating hypoxia as a cause for radioresistance..  115:10548-10550. 2018
  • ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins..  115:E9717-E9726. 2018
  • N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle..  115:8829-8834. 2018
  • Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish..  115:8805-8810. 2018
  • Acetyl-l-carnitine deficiency in patients with major depressive disorder..  115:8627-8632. 2018
  • Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy..  115:7869-7878. 2018
  • GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae..  115:E7109-E7118. 2018
  • The mutagen and carcinogen cadmium is a high-affinity inhibitor of the zinc-dependent MutLα endonuclease..  115:7314-7319. 2018
  • Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13..  115:6810-6815. 2018
  • CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy..  115:6261-6266. 2018
  • HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions..  115:6267-6272. 2018
  • CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch..  115:5986-5991. 2018
  • Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins..  115:5956-5961. 2018
  • Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock..  115:5980-5985. 2018
  • Spatial mutation patterns as markers of early colorectal tumor cell mobility..  115:5774-5779. 2018
  • Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy..  115:E4661-E4669. 2018
  • Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer..  115:E4473-E4482. 2018
  • Tunable cytotoxic aptamer-drug conjugates for the treatment of prostate cancer..  115:4761-4766. 2018
  • Earth BioGenome Project: Sequencing life for the future of life..  115:4325-4333. 2018
  • Molecular mechanism of activation of human musk receptors OR5AN1 and OR1A1 by (R)-muscone and diverse other musk-smelling compounds..  115:E3950-E3958. 2018
  • Reply to Gilchrist et al.: Possible roles for VAC14 in multiple infectious diseases..  115:E3604-E3605. 2018
  • S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy..  115:E3388-E3397. 2018
  • Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling..  115:3834-3839. 2018
  • PDGFRα + pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo..  115:E3173-E3181. 2018
  • Modulation of intestinal sulfur assimilation metabolism regulates iron homeostasis..  115:3000-3005. 2018
  • RNAi is a critical determinant of centromere evolution in closely related fungi..  115:3108-3113. 2018
  • Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema..  115:2788-2793. 2018
  • Mitotic waves in the early embryogenesis of Drosophila: Bistability traded for speed..  115:E2165-E2174. 2018
  • TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain..  115:E1657-E1666. 2018
  • Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP..  115:1298-1303. 2018
  • Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy..  115:561-566. 2018
  • Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody..  115:168-173. 2018
  • STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo..  114:E10928-E10936. 2017
  • Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency..  114:12743-12748. 2017
  • NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor..  114:E8458-E8467. 2017
  • Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer..  114:10455-10460. 2017
  • Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers..  114:10202-10207. 2017
  • Clipping of arginine-methylated histone tails by JMJD5 and JMJD7..  114:E7717-E7726. 2017
  • Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol..  114:E7746-E7755. 2017
  • Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood..  114:E7054-E7062. 2017
  • Proteolytic cleavage and PKA phosphorylation of α1C subunit are not required for adrenergic regulation of CaV1.2 in the heart..  114:9194-9199. 2017
  • Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies..  114:8614-8619. 2017
  • DNA-PK facilitates piggyBac transposition by promoting paired-end complex formation..  114:7408-7413. 2017
  • Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage..  114:E5530-E5538. 2017
  • Cortical neurons multiplex reward-related signals along with sensory and motor information..  114:E4841-E4850. 2017
  • Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion..  114:E4812-E4821. 2017
  • Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I..  114:6010-6015. 2017
  • Inducible Fgf13 ablation enhances caveolae-mediated cardioprotection during cardiac pressure overload..  114:E4010-E4019. 2017
  • Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair..  114:4930-4935. 2017
  • Trio-based exome sequencing arrests de novo mutations in early-onset high myopia..  114:4219-4224. 2017
  • Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection..  114:2711-2716. 2017
  • Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis..  114:2562-2567. 2017
  • Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems..  114:E1698-E1706. 2017
  • Deconstructing mammalian thermoregulation..  114:1765-1767. 2017
  • Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library..  114:1708-1713. 2017
  • Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness..  114:E590-E599. 2017
  • Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties..  113:E8178-E8186. 2016
  • Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae..  113:E8114-E8121. 2016
  • KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference..  113:14372-14377. 2016
  • β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility..  113:14426-14431. 2016
  • Genomic sequencing-based mutational enrichment analysis identifies motility genes in a genetically intractable gut microbe..  113:14127-14132. 2016
  • HIV-1 leader RNA dimeric interface revealed by NMR..  113:13263-13265. 2016
  • IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy..  113:E7572-E7579. 2016
  • Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis..  113:E7126-E7135. 2016
  • Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain..  113:12544-12549. 2016
  • Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels..  113:E6686-E6695. 2016
  • Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer..  113:E6457-E6466. 2016
  • DNA and RNA topoisomerase activities of Top3β are promoted by mediator protein Tudor domain-containing protein 3..  113:E5544-E5551. 2016
  • SHAPE reveals transcript-wide interactions, complex structural domains, and protein interactions across the Xist lncRNA in living cells..  113:10322-10327. 2016
  • Structures of the activator of K. pneumonia biofilm formation, MrkH, indicates PilZ domains involved in c-di-GMP and DNA binding..  113:10067-10072. 2016
  • Glimpse of natural selection of long-lived T-cell clones in healthy life..  113:9858-9863. 2016
  • Scavenging nucleic acid debris to combat autoimmunity and infectious disease..  113:9728-9733. 2016
  • ORChestrating the human DNA replication program..  113:9136-9138. 2016
  • Psychological resilience and the gene regulatory impact of posttraumatic stress in Nepali child soldiers..  113:8156-8161. 2016
  • Structure of human Niemann-Pick C1 protein..  113:8212-8217. 2016
  • Sympatric speciation of spiny mice, Acomys, unfolded transcriptomically at Evolution Canyon, Israel..  113:8254-8259. 2016
  • Transcriptome, genetic editing, and microRNA divergence substantiate sympatric speciation of blind mole rat, Spalax..  113:7584-7589. 2016
  • Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques..  113:E3413-E3422. 2016
  • USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds..  113:E2945-E2954. 2016
  • Polarized localization of voltage-gated Na+ channels is regulated by concerted FGF13 and FGF14 action..  113:E2665-E2674. 2016
  • Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ..  113:4988-4993. 2016
  • Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization..  113:4446-4451. 2016
  • Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function..  113:4320-4325. 2016
  • Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay.  113:4482-4487. 2016
  • Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay..  113:4482-4487. 2016
  • Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity..  113:3861-3866. 2016
  • Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice..  113:3428-3435. 2016
  • Focal expression of mutant huntingtin in the songbird basal ganglia disrupts cortico-basal ganglia networks and vocal sequences..  113:E1720-E1727. 2016
  • CXCL13 is a plasma biomarker of germinal center activity..  113:2702-2707. 2016
  • Metabolic stress is a barrier to Epstein-Barr virus-mediated B-cell immortalization..  113:E782-E790. 2016
  • APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases..  113:830-837. 2016
  • Dopamine: Context and counterfactuals..  113:22-23. 2016
  • Neural mechanisms of social decision-making in the primate amygdala..  112:16012-16017. 2015
  • Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators..  112:E7249-E7256. 2015
  • Inositol phosphate kinase 2 is required for imaginal disc development in Drosophila..  112:15660-15665. 2015
  • Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer..  112:E6945-E6954. 2015
  • Responsiveness of G protein-coupled odorant receptors is partially attributed to the activation mechanism..  112:14966-14971. 2015
  • Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission..  112:13645-13650. 2015
  • Myocardial NF-κB activation is essential for zebrafish heart regeneration..  112:13255-13260. 2015
  • Human pluripotent stem cell-derived neural constructs for predicting neural toxicity..  112:12516-12521. 2015
  • SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia..  112:12528-12533. 2015
  • Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis..  112:11714-11719. 2015
  • MutL traps MutS at a DNA mismatch..  112:10914-10919. 2015
  • STIM1 enhances SR Ca2+ content through binding phospholamban in rat ventricular myocytes..  112:E4792-E4801. 2015
  • Quantification of biological aging in young adults..  112:E4104-E4110. 2015
  • Suppression of conformational heterogeneity at a protein-protein interface..  112:9028-9033. 2015
  • N-linked glycosylation of protease-activated receptor-1 at extracellular loop 2 regulates G-protein signaling bias..  112:E3600-E3608. 2015
  • Reply to Turin et al.: Vibrational theory of olfaction is implausible..  112:E3155. 2015
  • Regulation of age-related macular degeneration-like pathology by complement factor H..  112:E3040-E3049. 2015
  • Hemoglobin βCys93 is essential for cardiovascular function and integrated response to hypoxia..  112:6425-6430. 2015
  • Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis..  112:6347-6352. 2015
  • Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease..  112:E2517-E2526. 2015
  • FtsZ filament capping by MciZ, a developmental regulator of bacterial division..  112:E2130-E2138. 2015
  • Telomere dysfunction causes alveolar stem cell failure..  112:5099-5104. 2015
  • Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation..  112:4678-4683. 2015
  • Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue..  112:4363-4368. 2015
  • T-cell receptor α enhancer is inactivated in αβ T lymphocytes..  112:E1744-E1753. 2015
  • L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro..  112:E1461-E1470. 2015
  • CD47 regulates the phagocytic clearance and replication of the Plasmodium yoelii malaria parasite..  112:3062-3067. 2015
  • Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection..  112:E992-E999. 2015
  • Epigenetic control of intestinal barrier function and inflammation in zebrafish..  112:2770-2775. 2015
  • Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion..  112:2888-2893. 2015
  • Mutant IDH is sufficient to initiate enchondromatosis in mice..  112:2829-2834. 2015
  • Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress..  112:2557-2562. 2015
  • Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABAA receptors..  112:1214-1219. 2015
  • Giant ankyrin-G: a critical innovation in vertebrate evolution of fast and integrated neuronal signaling..  112:957-964. 2015
  • Plasmon-assisted photothermal catalytic reactor for hydrogen generation 2015
  • Expression and prognostic impact of lncRNAs in acute myeloid leukemia..  111:18679-18684. 2014
  • Identification of S-nitroso-CoA reductases that regulate protein S-nitrosylation..  111:18572-18577. 2014
  • Functionally compromised CHD7 alleles in patients with isolated GnRH deficiency..  111:17953-17958. 2014
  • Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage..  111:E5114-E5122. 2014
  • G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy..  111:15756-15761. 2014
  • CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors..  111:E4468-E4477. 2014
  • Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma..  111:13876-13881. 2014
  • Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels..  111:E4006-E4014. 2014
  • IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells..  111:E3641-E3649. 2014
  • Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease..  111:E3366. 2014
  • A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion..  111:11163-11168. 2014
  • Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains..  111:10275-10280. 2014
  • MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation..  111:E2807-E2816. 2014
  • Invisible RNA state dynamically couples distant motifs..  111:9485-9490. 2014
  • Abrogation of α-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats..  111:9289-9294. 2014
  • Redemption of autoreactive B cells..  111:9022-9023. 2014
  • A "microRNA-like" small RNA expressed by Dengue virus?.  111:E2359. 2014
  • Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis..  111:E2384-E2393. 2014
  • Childhood bullying involvement predicts low-grade systemic inflammation into adulthood..  111:7570-7575. 2014
  • Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death..  111:7391-7396. 2014
  • The evolution of self-control..  111:E2140-E2148. 2014
  • GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling..  111:E2008-E2017. 2014
  • Defining functional DNA elements in the human genome..  111:6131-6138. 2014
  • Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS..  111:6046-6051. 2014
  • Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo..  111:5508-5513. 2014
  • Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors..  111:5242-5247. 2014
  • T cells down-regulate macrophage TNF production by IRAK1-mediated IL-10 expression and control innate hyperinflammation..  111:5295-5300. 2014
  • Improving the lens design and performance of a contemporary electromagnetic shock wave lithotripter..  111:E1167-E1175. 2014
  • Activating mutations in STIM1 and ORAI1 cause overlapping syndromes of tubular myopathy and congenital miosis..  111:4197-4202. 2014
  • Pregnancy without progesterone in horses defines a second endogenous biopotent progesterone receptor agonist, 5α-dihydroprogesterone..  111:3365-3370. 2014
  • Functional and genetic studies of isolated cells from parathyroid tumors reveal the complex pathogenesis of parathyroid neoplasia..  111:3092-3097. 2014
  • Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function..  111:E776-E783. 2014
  • Genetic predisposition of behavioral response..  111:1672-1673. 2014
  • Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival..  111:E582-E591. 2014
  • Structure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimer..  111:1391-1396. 2014
  • TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading..  111:1316-1321. 2014
  • Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling..  111:990-995. 2014
  • PIP5K1α inhibition as a therapeutic strategy for prostate cancer 2014
  • PIP5K1α inhibition as a therapeutic strategy for prostate cancer.  111:12578-12579. 2014
  • Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins..  110:20248-20253. 2013
  • Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells..  110:20111-20116. 2013
  • Genome rearrangements caused by interstitial telomeric sequences in yeast..  110:19866-19871. 2013
  • Gene product 0.4 increases bacteriophage T7 competitiveness by inhibiting host cell division..  110:19549-19554. 2013
  • Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2..  110:E4628-E4637. 2013
  • Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain..  110:E4279-E4288. 2013
  • Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors..  110:18214-18219. 2013
  • Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk..  110:18220-18225. 2013
  • Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology..  110:E4069-E4078. 2013
  • Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice..  110:17362-17367. 2013
  • Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair..  110:16874-16879. 2013
  • Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation..  110:E3820-E3829. 2013
  • GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding..  110:16211-16216. 2013
  • Whole genome sequencing in patients with retinitis pigmentosa reveals pathogenic DNA structural changes and NEK2 as a new disease gene..  110:16139-16144. 2013
  • Postreward delays and systematic biases in measures of animal temporal discounting..  110:15491-15496. 2013
  • Expanding the primate body schema in sensorimotor cortex by virtual touches of an avatar..  110:15121-15126. 2013
  • Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans..  110:14468-14473. 2013
  • UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling..  110:E3225-E3234. 2013
  • Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia..  110:13552-13557. 2013
  • Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration..  110:13416-13421. 2013
  • Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival..  110:12432-12437. 2013
  • Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation..  110:12277-12282. 2013
  • Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model..  110:12006-12011. 2013
  • Oxytocin blunts social vigilance in the rhesus macaque..  110:11630-11635. 2013
  • S-nitrosylation therapy to improve oxygen delivery of banked blood..  110:11529-11534. 2013
  • Liposome division by a simple bacterial division machinery..  110:11000-11004. 2013
  • SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid..  110:10586-10591. 2013
  • Neuroethology of primate social behavior..  110 Suppl 2:10387-10394. 2013
  • Targeting of the MNK-eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function..  110:E2298-E2307. 2013
  • Proteasome overload is a common stress factor in multiple forms of inherited retinal degeneration..  110:9986-9991. 2013
  • Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected]..  110:9356-9361. 2013
  • Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG..  110:9019-9024. 2013
  • Control of electrolyte balance through ubiquitination..  110:7535-7536. 2013
  • Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis..  110:7790-7795. 2013
  • Bimodal quantitative relationships between histone modifications for X-linked and autosomal loci..  110:6949-6954. 2013
  • Phenotypic properties of transmitted founder HIV-1..  110:6626-6633. 2013
  • Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains..  110:6470-6475. 2013
  • Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain..  110:5921-5926. 2013
  • TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal..  110:6021-6026. 2013
  • TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses..  110:6157-6162. 2013
  • Role for cytoplasmic nucleotide hydrolysis in hepatic function and protein synthesis..  110:5040-5045. 2013
  • Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter..  110:4315-4320. 2013
  • Animals in a bacterial world, a new imperative for the life sciences..  110:3229-3236. 2013
  • DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge..  110:2975-2980. 2013
  • Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control..  110:2792-2797. 2013
  • Biomimetic, synthetic HDL nanostructures for lymphoma..  110:2511-2516. 2013
  • Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells..  110:2300-2305. 2013
  • Genetic heterogeneity of diffuse large B-cell lymphoma..  110:1398-1403. 2013
  • Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia..  110:240-245. 2013
  • Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody..  110:264-269. 2013
  • Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma..  110:270-275. 2013
  • Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets.  E4762-4769. 2013
  • Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells.  20111-20116. 2013
  • Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action..  109:20732-20737. 2012
  • Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub..  109:E3493-E3502. 2012
  • Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains..  109:19769-19774. 2012
  • Aberrant S-nitrosylation mediates calcium-triggered ventricular arrhythmia in the intact heart..  109:18186-18191. 2012
  • Locomotor head movements and semicircular canal morphology in primates..  109:17914-17919. 2012
  • Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways..  109:17603-17608. 2012
  • Modified SH2 domain to phototrap and identify phosphotyrosine proteins from subcellular sites within cells..  109:E2929-E2938. 2012
  • Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates..  109:16504-16509. 2012
  • Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction..  109:16354-16359. 2012
  • Persistent cannabis users show neuropsychological decline from childhood to midlife..  109:E2657-E2664. 2012
  • Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death..  109:E2343-E2352. 2012
  • Tumor suppressor TSC1 is critical for T-cell anergy..  109:14152-14157. 2012
  • Functional epialleles at an endogenous human centromere..  109:13704-13709. 2012
  • Autophagic activity dictates the cellular response to oncogenic RAS..  109:13325-13330. 2012
  • Nucleic acid scavengers inhibit thrombosis without increasing bleeding..  109:12938-12943. 2012
  • β-Arrestin2 mediates the initiation and progression of myeloid leukemia..  109:12532-12537. 2012
  • Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma..  109:11818-11823. 2012
  • CD45-deficient severe combined immunodeficiency caused by uniparental disomy..  109:10456-10461. 2012
  • NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis..  109:10480-10485. 2012
  • Reciprocal uniparental disomy in yeast..  109:9947-9952. 2012
  • Distinct CD4+ helper T cells involved in primary and secondary responses to infection..  109:9511-9516. 2012
  • Brain anomalies in children exposed prenatally to a common organophosphate pesticide..  109:7871-7876. 2012
  • The protein expression landscape of the Arabidopsis root..  109:6811-6818. 2012
  • Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma..  109:4910-4915. 2012
  • Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners..  109:4834-4839. 2012
  • Rapid self-healing hydrogels..  109:4383-4388. 2012
  • Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular function..  109:4314-4319. 2012
  • Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans..  109:3985-3990. 2012
  • Calcium-based plasticity model explains sensitivity of synaptic changes to spike pattern, rate, and dendritic location..  109:3991-3996. 2012
  • Crucial role of copper in detection of metal-coordinating odorants..  109:3492-3497. 2012
  • Leukocyte composition of human breast cancer..  109:2796-2801. 2012
  • MicroRNA expression by an oncogenic retrovirus..  109:2695-2696. 2012
  • The channel kinase, TRPM7, is required for early embryonic development..  109:E225-E233. 2012
  • Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches..  109:1263-1268. 2012
  • Inhaled oxytocin amplifies both vicarious reinforcement and self reinforcement in rhesus macaques (Macaca mulatta)..  109:959-964. 2012
  • Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression.  1643-1648. 2012
  • Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling.  E3395-E3404. 2012
  • Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition..  108:E1475-E1483. 2011
  • Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase..  108:21046-21051. 2011
  • Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways..  108:21188-21193. 2011
  • Antigen-specific induced Foxp3+ regulatory T cells are generated following CD40/CD154 blockade..  108:20701-20706. 2011
  • IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis..  108:20736-20741. 2011
  • β-Arrestin and dishevelled coordinate biased signaling..  108:19839-19840. 2011
  • Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy..  108:18488-18493. 2011
  • Epigenome characterization at single base-pair resolution..  108:18318-18323. 2011
  • Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation..  108:18348-18353. 2011
  • Polymorphisms in fibronectin binding protein A of Staphylococcus aureus are associated with infection of cardiovascular devices..  108:18372-18377. 2011
  • Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis..  108:17644-17648. 2011
  • Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1)..  108:17462-17467. 2011
  • Retraction for Garman et al: A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities..  108:17569. 2011
  • Implications for proteasome nuclear localization revealed by the structure of the nuclear proteasome tether protein Cut8..  108:16950-16955. 2011
  • Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors..  108:16651-16656. 2011
  • Longitudinal evidence that fatherhood decreases testosterone in human males..  108:16194-16199. 2011
  • Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4..  108:16098-16103. 2011
  • Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus..  108:14590-14595. 2011
  • Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production..  108:14608-14613. 2011
  • Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin..  108:14216-14221. 2011
  • Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity..  108:E523. 2011
  • Nucleic acid-binding polymers as anti-inflammatory agents..  108:14055-14060. 2011
  • Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC..  108:E440-E449. 2011
  • G protein G(alpha)o is essential for vomeronasal function and aggressive behavior in mice..  108:12898-12903. 2011
  • High-resolution, noninvasive longitudinal live imaging of immune responses..  108:12863-12868. 2011
  • Relation of addiction genes to hypothalamic gene changes subserving genesis and gratification of a classic instinct, sodium appetite..  108:12509-12514. 2011
  • Activation-induced cytidine deaminase mediates central tolerance in B cells..  108:11560-11565. 2011
  • Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration..  108:E279-E287. 2011
  • Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli..  108:11387-11392. 2011
  • Resting-state activity in development and maintenance of normal brain function..  108:11638-11643. 2011
  • Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures..  108:11440-11445. 2011
  • Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis..  108:10284-10289. 2011
  • Loss of Bardet-Biedl syndrome protein-8 (BBS8) perturbs olfactory function, protein localization, and axon targeting..  108:10320-10325. 2011
  • Decellularized tissue-engineered blood vessel as an arterial conduit..  108:9214-9219. 2011
  • Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance..  108:9190-9195. 2011
  • TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity..  108:8485-8490. 2011
  • Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates..  108:7131-7136. 2011
  • Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process..  108:6591-6596. 2011
  • Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration..  108:6241-6245. 2011
  • Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner..  108:5795-5800. 2011
  • Distinct neural signatures of threat learning in adolescents and adults..  108:4500-4505. 2011
  • Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway..  108:3141-3146. 2011
  • Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome..  108:3270-3275. 2011
  • Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-beta signaling..  108:3395-3400. 2011
  • Outcrossing, mitotic recombination, and life-history trade-offs shape genome evolution in Saccharomyces cerevisiae..  108:1987-1992. 2011
  • Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation..  108:2088-2093. 2011
  • Role for topoisomerase 1 in transcription-associated mutagenesis in yeast..  108:698-703. 2011
  • Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin..  108:149-154. 2011
  • Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning..  108:167-172. 2011
  • X-ray diffraction evidence for myosin-troponin connections and tropomyosin movement during stretch activation of insect flight muscle..  108:120-125. 2011
  • Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal.  7962-7967. 2011
  • Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction..  107:21110-21115. 2010
  • Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding..  107:20974-20979. 2010
  • NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment..  107:20477-20482. 2010
  • Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline..  107:20518-20522. 2010
  • Political economy of marine reserves: understanding the role of opportunity costs..  107:18300-18305. 2010
  • Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis..  107:17345-17350. 2010
  • In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation..  107:16432-16437. 2010
  • PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair..  107:16066-16071. 2010
  • Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)..  107:15299-15304. 2010
  • Plasticity of lipid-protein interactions in the function and topogenesis of the membrane protein lactose permease from Escherichia coli..  107:15057-15062. 2010
  • Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo..  107:14351-14356. 2010
  • Dissecting cell adhesion cross-talk with micropatterns..  107:13199-13200. 2010
  • PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance..  107:13384-13389. 2010
  • Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus)..  107:11889-11894. 2010
  • Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition..  107:11763-11768. 2010
  • Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms..  107:11465-11470. 2010
  • Hsp 70/Hsp 90 organizing protein as a nitrosylation target in cystic fibrosis therapy..  107:11393-11398. 2010
  • Systemically dispersed innate IL-13-expressing cells in type 2 immunity..  107:11489-11494. 2010
  • Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome..  107:10602-10607. 2010
  • Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates..  107:10655-10660. 2010
  • Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction..  107:10178-10183. 2010
  • Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway..  107:9424-9429. 2010
  • Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine..  107:9323-9328. 2010
  • Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1- and Th2-polarizing adjuvants..  107:8334-8339. 2010
  • Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases..  107:7521-7526. 2010
  • From the Cover: mitotic gene conversion events induced in G1-synchronized yeast cells by gamma rays are similar to spontaneous conversion events..  107:7383-7388. 2010
  • Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration..  107:7401-7406. 2010
  • Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)..  107:7395-7400. 2010
  • A pathway-based classification of human breast cancer..  107:6994-6999. 2010
  • Drosophila topo IIIalpha is required for the maintenance of mitochondrial genome and male germ-line stem cells..  107:6228-6233. 2010
  • Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution..  107:5972-5977. 2010
  • In vivo vomeronasal stimulation reveals sensory encoding of conspecific and allospecific cues by the mouse accessory olfactory bulb..  107:5172-5177. 2010
  • Kinetics of brain nicotine accumulation in dependent and nondependent smokers assessed with PET and cigarettes containing 11C-nicotine..  107:5190-5195. 2010
  • Leptin therapy in insulin-deficient type I diabetes..  107:4813-4819. 2010
  • Leveraging leptin for type I diabetes?.  107:4793-4794. 2010
  • Pain perception is altered by a nucleotide polymorphism in SCN9A..  107:5148-5153. 2010
  • Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity..  107:4908-4913. 2010
  • Toward discovery science of human brain function..  107:4734-4739. 2010
  • ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS..  107:4153-4158. 2010
  • Molecular MRI for sensitive and specific detection of lung metastases..  107:3693-3697. 2010
  • Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells..  107:2556-2561. 2010
  • Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7..  107:628-632. 2010
  • Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance..  107:181-186. 2010
  • Sinorhizobium meliloti phospholipase C required for lipid remodeling during phosphorus limitation..  107:302-307. 2010
  • Basal epithelial stem cells are efficient targets for prostate cancer initiation.  107:2610-2615. 2010
  • Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium.  17298-17303. 2010
  • Quantifying cellular traction forces in three dimensions..  106:22108-22113. 2009
  • The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency..  106:22323-22328. 2009
  • Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates..  106:21247-21251. 2009
  • Role of HIV membrane in neutralization by two broadly neutralizing antibodies..  106:20234-20239. 2009
  • Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus..  106:19934-19939. 2009
  • A protein microarray-based analysis of S-nitrosylation..  106:18948-18953. 2009
  • p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo..  106:19035-19039. 2009
  • Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease..  106:18831-18836. 2009
  • Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity..  106:17469-17474. 2009
  • AnkyrinG is required to maintain axo-dendritic polarity in vivo..  106:17564-17569. 2009
  • ABCs of erythroid mitochondrial iron uptake..  106:16012-16013. 2009
  • DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge..  106:15831-15836. 2009
  • Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice..  106:15956-15960. 2009
  • Spontaneous cortical activity in awake monkeys composed of neuronal avalanches..  106:15921-15926. 2009
  • In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics..  106:15231-15236. 2009
  • Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice..  106:15472-15477. 2009
  • TLR4-mediated expulsion of bacteria from infected bladder epithelial cells..  106:14966-14971. 2009
  • Conformational selection or induced fit: a flux description of reaction mechanism..  106:13737-13741. 2009
  • Epistasis between RET and BBS mutations modulates enteric innervation and causes syndromic Hirschsprung disease..  106:13921-13926. 2009
  • Basal cells as stem cells of the mouse trachea and human airway epithelium..  106:12771-12775. 2009
  • Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists..  106:12178-12183. 2009
  • NPAS3 is a trachealess homolog critical for lung development and homeostasis..  106:11691-11696. 2009
  • Cellular immune response to cryptic epitopes during therapeutic gene transfer..  106:10770-10774. 2009
  • SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice..  106:10207-10212. 2009
  • Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands..  106:9649-9654. 2009
  • Mirroring of attention by neurons in macaque parietal cortex..  106:9489-9494. 2009
  • Modeling the physics of FtsZ assembly and force generation..  106:9238-9243. 2009
  • Stem cells are dispensable for lung homeostasis but restore airways after injury..  106:9286-9291. 2009
  • A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma..  106:9099-9104. 2009
  • A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair..  106:8495-8500. 2009
  • Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma..  106:8683-8688. 2009
  • The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42..  106:8221-8226. 2009
  • "To learn, you must pay attention." Molecular insights into teachers' wisdom..  106:7267-7268. 2009
  • Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication..  106:7577-7582. 2009
  • Phycomyces MADB interacts with MADA to form the primary photoreceptor complex for fungal phototropism..  106:7095-7100. 2009
  • Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2..  106:6650-6655. 2009
  • Endogenous S-nitrosothiols protect against myocardial injury..  106:6297-6302. 2009
  • Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component..  106:6099-6104. 2009
  • Electrophysiological correlates of default-mode processing in macaque posterior cingulate cortex..  106:5948-5953. 2009
  • Glucocorticoid regulation of preproglucagon transcription and RNA stability during stress..  106:5913-5918. 2009
  • Single-round selection yields a unique retroviral envelope utilizing GPR172A as its host receptor..  106:5848-5853. 2009
  • The mismatch repair system promotes DNA polymerase zeta-dependent translesion synthesis in yeast..  106:5749-5754. 2009
  • Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer..  106:5312-5317. 2009
  • MetJ repressor interactions with DNA probed by in-cell NMR..  106:5065-5069. 2009
  • Computational structure-based redesign of enzyme activity..  106:3764-3769. 2009
  • Dynamic duo takes down fungal villains..  106:2971-2972. 2009
  • MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction..  106:3507-3512. 2009
  • Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease..  106:2818-2823. 2009
  • Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate..  106:2041-2046. 2009
  • Nicotine activates TRPM5-dependent and independent taste pathways..  106:1596-1601. 2009
  • Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4..  106:1626-1631. 2009
  • Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism..  106:719-724. 2009
  • Trimorphic stepping stones pave the way to fungal virulence..  106:351-352. 2009
  • Functional comparison of RGS9 splice isoforms in a living cell..  105:20988-20993. 2008
  • In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells..  105:20641-20646. 2008
  • A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities..  105:19432-19437. 2008
  • Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo..  105:19126-19131. 2008
  • The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo..  105:19544-19549. 2008
  • Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair..  105:16906-16911. 2008
  • Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development..  105:16626-16630. 2008
  • Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer..  105:14814-14819. 2008
  • Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation..  105:14555-14560. 2008
  • ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms..  105:14527-14532. 2008
  • Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics..  105:13656-13661. 2008
  • Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways..  105:13520-13525. 2008
  • Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo..  105:13063-13068. 2008
  • Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses..  105:13015-13020. 2008
  • High-resolution magnetic resonance histology of the embryonic and neonatal mouse: a 4D atlas and morphologic database..  105:12331-12336. 2008
  • Potential landscape and flux framework of nonequilibrium networks: robustness, dissipation, and coherence of biochemical oscillations..  105:12271-12276. 2008
  • TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells..  105:12611-12616. 2008
  • A role for a lithium-inhibited Golgi nucleotidase in skeletal development and sulfation..  105:11605-11612. 2008
  • Double-strand breaks associated with repetitive DNA can reshape the genome..  105:11845-11850. 2008
  • Synergistic control of T cell development and tumor suppression by diacylglycerol kinase alpha and zeta..  105:11909-11914. 2008
  • A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys..  105:10489-10494. 2008
  • Reverse actin sliding triggers strong myosin binding that moves tropomyosin..  105:10372-10377. 2008
  • Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptors..  105:9988-9993. 2008
  • Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole..  105:9379-9384. 2008
  • Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression..  105:8718-8723. 2008
  • Dimeric subunit stoichiometry of the human voltage-dependent proton channel Hv1..  105:7692-7695. 2008
  • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection..  105:7552-7557. 2008
  • Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells..  105:7235-7239. 2008
  • Four-dimensional analysis of vascularization during primary development of an organ, the gonad..  105:7212-7217. 2008
  • Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae..  105:7194-7199. 2008
  • Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression..  105:6912-6917. 2008
  • Regression supports two mechanisms of fork processing in phage T4..  105:6852-6857. 2008
  • Acetylcholinesterase inhibition and Gulf War illnesses: conclusions are not supported by independent reviews of the same evidence..  105:E20. 2008
  • Lithium may slow progression of amyotrophic lateral sclerosis, but further study is needed..  105:E17. 2008
  • A mitotic recombination system for mouse chromosome 17..  105:4237-4241. 2008
  • Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons..  105:4441-4446. 2008
  • Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter..  105:4405-4410. 2008
  • Electroactive controlled release thin films..  105:2280-2285. 2008
  • A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus..  105:1698-1703. 2008
  • Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence..  105:1215-1220. 2008
  • Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency..  105:1333-1338. 2008
  • Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice..  104:20878-20883. 2007
  • Mutations of HNF-1beta inhibit epithelial morphogenesis through dysregulation of SOCS-3..  104:20386-20391. 2007
  • Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1..  104:19867-19872. 2007
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