Molecular Cell

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  Publication Venue For

  • The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy..  73:429-445.e7. 2019
  • LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling..  72:601. 2018
  • LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling..  72:71-83.e7. 2018
  • Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease..  72:152-161.e7. 2018
  • SRCP1 Conveys Resistance to Polyglutamine Aggregation..  71:216-228.e7. 2018
  • MLKL Requires the Inositol Phosphate Code to Execute Necroptosis..  70:936-948.e7. 2018
  • p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis..  70:984. 2018
  • S-Nitrosylation of β-Arrestins Biases Receptor Signaling and Confers Ligand Independence..  70:473-487.e6. 2018
  • p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis..  70:663-678.e6. 2018
  • A Multiplex Enzymatic Machinery for Cellular Protein S-nitrosylation..  69:451-464.e6. 2018
  • Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast..  67:539-549.e4. 2017
  • Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy..  66:684-697.e9. 2017
  • A Flick of the Tail Keeps the Circadian Clock in Line..  66:437-438. 2017
  • Expanding the CRISPR Toolbox: Targeting RNA with Cas13b..  65:582-584. 2017
  • Isoform Switch of TET1 Regulates DNA Demethylation and Mouse Development..  64:1062-1073. 2016
  • The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis..  61:187-198. 2016
  • Mre11-Sae2 and RPA Collaborate to Prevent Palindromic Gene Amplification..  60:500-508. 2015
  • Perspectives on Unidirectional versus Divergent Transcription..  60:348-349. 2015
  • A Period2 Phosphoswitch Regulates and Temperature Compensates Circadian Period..  60:77-88. 2015
  • SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression.  59:917-930. 2015
  • PKCs Sweeten Cell Metabolism by Phosphorylation of Glut1..  58:711-712. 2015
  • Caspase-3 promotes genetic instability and carcinogenesis..  58:284-296. 2015
  • Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth..  57:537-551. 2015
  • Human promoters are intrinsically directional..  57:674-684. 2015
  • Caspase-3 Promotes Genetic Instability and Carcinogenesis.  58:284-296. 2015
  • RIP3 induces apoptosis independent of pronecrotic kinase activity..  56:481-495. 2014
  • Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases..  54:5-16. 2014
  • Staying alive: cell death in antiviral immunity..  54:273-280. 2014
  • Salicylic acid activates DNA damage responses to potentiate plant immunity.  52:602-610. 2013
  • Distinct properties of cell-type-specific and shared transcription factor binding sites..  52:25-36. 2013
  • A P(E)RM(I)T for BMP signaling..  51:1-2. 2013
  • SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase..  50:686-698. 2013
  • Errata to Cyclin-dependent kinases are regulators and effectors of oscillations driven by a transcription factor network [Molecular Cell, 45 (2012) 669-679].  49:1177-1179. 2013
  • The tangled circuitry of metabolism and apoptosis..  49:399-410. 2013
  • Distinct properties of cell-type-specific and shared transcription factor binding sites.  52:25-36. 2013
  • Errata to Cyclin-dependent kinases are regulators and effectors of oscillations driven by a transcription factor network [Molecular Cell, 45 (2012) 669-679].  49:1177-1179. 2013
  • PGC-1 coactivators regulate MITF and the tanning response..  49:145-157. 2013
  • Proteasomes Activate Aggresome Disassembly and Clearance by Producing Unanchored Ubiquitin Chains.  51:819-828. 2013
  • Salicylic Acid Activates DNA Damage Responses to Potentiate Plant Immunity 2013
  • Molecular basis for a protein-mediated DNA-bridging mechanism that functions in condensation of the E. coli chromosome..  48:560-571. 2012
  • A direct HDAC4-MAP kinase crosstalk activates muscle atrophy program..  47:122-132. 2012
  • Cyclin-dependent kinases are regulators and effectors of oscillations driven by a transcription factor network..  45:669-679. 2012
  • SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome..  44:177-190. 2011
  • mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR..  44:290-303. 2011
  • A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2..  43:834-842. 2011
  • Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability.  43:327-339. 2011
  • Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability..  43:327-339. 2011
  • Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP..  43:599-612. 2011
  • Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop..  43:57-71. 2011
  • PKM2 and the tricky balance of growth and energy in cancer..  42:713-714. 2011
  • Seeking Resolution: Budding Yeast Enzymes Finally Make the Cut.  40:858-859. 2010
  • Structure of the endonuclease domain of MutL: unlicensed to cut..  39:145-151. 2010
  • Molecular structures of crossover and noncrossover intermediates during gap repair in yeast: implications for recombination..  38:211-222. 2010
  • Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement..  38:305-315. 2010
  • Unconventional ubiquitin recognition by the ubiquitin-binding motif within the Y family DNA polymerases iota and Rev1..  37:408-417. 2010
  • A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral MicroRNAs..  37:135-142. 2010
  • A genomic strategy to elucidate modules of oncogenic pathway signaling networks..  34:104-114. 2009
  • From promiscuity to precision: protein phosphatases get a makeover..  33:537-545. 2009
  • A Cut Above the Other Caspases.  35:733-734. 2009
  • Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26..  32:180-189. 2008
  • S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking..  31:395-405. 2008
  • Not-so-pseudo a substrate: Acm1-mediated inhibition of the APC..  30:543-544. 2008
  • Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα.  29:112-121. 2008
  • A Hierarchical Network of Transcription Factors Governs Androgen Receptor-Dependent Prostate Cancer Growth.  27:380-392. 2007
  • HDAC6 modulates cell motility by altering the acetylation level of cortactin..  27:197-213. 2007
  • Structure of the human MutSalpha DNA lesion recognition complex..  26:579-592. 2007
  • Regulation of HIF-1alpha stability through S-nitrosylation..  26:63-74. 2007
  • Structural Mechanism of Organic Hydroperoxide Induction of the Transcription Regulator OhrR.  28:652-664. 2007
  • Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs..  24:797-803. 2006
  • New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors..  24:643-652. 2006
  • Large conformational changes in a kinesin motor catalyzed by interaction with microtubules..  23:913-923. 2006
  • Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms..  23:37-48. 2006
  • The Kelch Proteins Gpb1 and Gpb2 Inhibit Ras Activity via Association with the Yeast RasGAP Neurofibromin Homologs Ira1 and Ira2.  22:819-830. 2006
  • A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada..  20:117-129. 2005
  • Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family..  20:131-141. 2005
  • Spatial and Temporal Recruitment of Androgen Receptor and Its Coactivators Involves Chromosomal Looping and Polymerase Tracking.  19:631-642. 2005
  • Cyclophilin B escorts the hepatitis C virus RNA polymerase: a viral achilles heel?.  19:145-146. 2005
  • Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells..  19:197-207. 2005
  • HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor..  18:601-607. 2005
  • Structural basis for an unexpected mode of SERM-mediated ER antagonism..  18:413-424. 2005
  • HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression..  17:793-803. 2005
  • Transcription and processing of human microRNA precursors..  16:861-865. 2004
  • Leveling the playing field..  15:491-492. 2004
  • The compact chromatin structure of a Ty repeated sequence suppresses recombination hotspot activity in Saccharomyces cerevisiae..  15:221-231. 2004
  • A defined human system that supports bidirectional mismatch-provoked excision..  15:31-41. 2004
  • Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay..  13:91-100. 2004
  • Myosins motor Miranda..  12:1346-1347. 2003
  • Posttranscriptional generation of macromolecular complexes..  12:1347-1349. 2003
  • Mechanism of 5'-directed excision in human mismatch repair..  12:1077-1086. 2003
  • Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation..  12:1287-1300. 2003
  • PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation..  12:1225-1237. 2003
  • Skp2 regulates Myc protein stability and activity..  11:1177-1188. 2003
  • Erratum: RNAi-mediated PTB depletion leads to enhanced exon definition (Molecular Cell (October 2002) 10 (943-949).  10:1535. 2002
  • The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p..  10:1429-1439. 2002
  • RNAi-mediated PTB depletion leads to enhanced exon definition..  10:943-949. 2002
  • The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits..  10:163-173. 2002
  • The Gα Protein Gpa2 Controls Yeast Differentiation by Interacting with Kelch Repeat Proteins that Mimic Gβ Subunits.  10:163-173. 2002
  • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells..  9:1327-1333. 2002
  • Eukaryotic mRNPs may represent posttranscriptional operons..  9:1161-1167. 2002
  • Replication, recombination, and repair: going for the gold..  9:471-480. 2002
  • Hfq: a bacterial Sm-like protein that mediates RNA-RNA interaction..  9:23-30. 2002
  • Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication.  9:481-491. 2002
  • Unexpected effects of FERM domain mutations on catalytic activity of Jak3: structural implication for Janus kinases..  8:959-969. 2001
  • Two closely related human nuclear export factors utilize entirely distinct export pathways..  8:397-406. 2001
  • Myc requires distinct E2F activities to induce S phase and apoptosis..  8:105-113. 2001
  • Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene..  7:823-832. 2001
  • Bacteriophage T4 proteins replicate plasmids with a preformed R loop at the T4 ori(uvsY) replication origin in vitro..  7:31-41. 2001
  • Tuberin-dependent membrane localization of polycystin-1: A functional link between polycystic kidney disease and the TSC2 tumor suppressor gene.  7:823-832. 2001
  • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues..  6:1389-1399. 2000
  • In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability..  6:683-692. 2000
  • DNA polymerase ζ introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae.  6:1491-1499. 2000
  • Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men.  3:1-10. 1999
  • SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.  4:175-186. 1999
  • Bacteriophage T4 initiates bidirectional DNA replication through a two-step process..  2:693-701. 1998
  • p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities..  2:305-316. 1998