Oncogene

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  Publication Venue For

  • Chronic hypoxia favours adoption to a castration-resistant cell state in prostate cancer..  42:1693-1703. 2023
  • A novel network pharmacology approach for leukaemia differentiation therapy using Mogrify®..  41:5160-5175. 2022
  • Correction: TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice..  41:4485. 2022
  • TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice..  41:3423-3432. 2022
  • Correction: Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells..  41:1225-1226. 2022
  • Targeting glutamine metabolism network for the treatment of therapy-resistant prostate cancer..  41:1140-1154. 2022
  • SFPQ promotes an oncogenic transcriptomic state in melanoma..  40:5192-5203. 2021
  • DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway..  40:2018-2034. 2021
  • Long-chain fatty acyl-CoA synthetase 1 promotes prostate cancer progression by elevation of lipogenesis and fatty acid beta-oxidation..  40:1806-1820. 2021
  • Plectin is a regulator of prostate cancer growth and metastasis..  40:663-676. 2021
  • EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer..  39:6757-6775. 2020
  • Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal..  39:5373-5389. 2020
  • Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis..  39:3276-3291. 2020
  • BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis..  38:7281-7293. 2019
  • PORCN inhibition synergizes with PI3K/mTOR inhibition in Wnt-addicted cancers..  38:6662-6677. 2019
  • Correction: Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner..  38:6566. 2019
  • Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate..  38:6507-6520. 2019
  • Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness..  38:5367-5380. 2019
  • Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner..  38:5321-5337. 2019
  • Increased type III TGF-β receptor shedding decreases tumorigenesis through induction of epithelial-to-mesenchymal transition..  38:3402-3414. 2019
  • Pentose conversions support the tumorigenesis of pancreatic cancer distant metastases..  37:5248-5256. 2018
  • xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression..  37:5007-5019. 2018
  • Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway..  37:3778-3789. 2018
  • miR-21 depletion in macrophages promotes tumoricidal polarization and enhances PD-1 immunotherapy..  37:3151-3165. 2018
  • Targeting UDP-α-D-glucose 6-dehydrogenase inhibits glioblastoma growth and migration..  37:2615-2629. 2018
  • A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer..  37:1911-1925. 2018
  • GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers..  37:1340-1353. 2018
  • Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis..  37:363-376. 2018
  • Inhibition of the androgen receptor induces a novel tumor promoter, ZBTB46, for prostate cancer metastasis..  36:6213-6224. 2017
  • Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasis..  36:5757-5767. 2017
  • Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling..  36:4379. 2017
  • Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling..  36:4235-4242. 2017
  • Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype..  36:4224-4232. 2017
  • Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms..  36:3934-3942. 2017
  • TET2 binds the androgen receptor and loss is associated with prostate cancer..  36:2172-2183. 2017
  • The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment..  35:6053-6064. 2016
  • Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways..  35:4302-4311. 2016
  • Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression..  35:4312-4320. 2016
  • N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN..  35:3335-3341. 2016
  • Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis..  35:2390-2397. 2016
  • Wnt addiction of genetically defined cancers reversed by PORCN inhibition..  35:2197-2207. 2016
  • Myogenic transcription factors regulate pro-metastatic miR-182..  35:1868-1875. 2016
  • Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism..  35:1373-1385. 2016
  • Fibulin-3 is a novel TGF-β pathway inhibitor in the breast cancer microenvironment..  34:5635-5647. 2015
  • Effects of physiological and synthetic IAP antagonism on c-IAP-dependent signaling..  34:5472-5481. 2015
  • Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer..  34:4821-4833. 2015
  • Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling..  34:4078-4088. 2015
  • LKB1 reduces ROS-mediated cell damage via activation of p38..  34:3848-3859. 2015
  • Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma..  34:3770-3779. 2015
  • Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism..  34:3296-3304. 2015
  • PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling..  34:2061-2071. 2015
  • The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense..  34:1799-1810. 2015
  • Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells..  34:546-557. 2015
  • Casein kinase 1 regulates Sprouty2 in FGF-ERK signaling..  34:474-484. 2015
  • Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch..  33:5251-5261. 2014
  • Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling..  33:3970-3979. 2014
  • High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7's induction of DNA damage response, an activity mediated by E7's inactivation of pocket proteins..  33:3383-3391. 2014
  • ELF3 is a repressor of androgen receptor action in prostate cancer cells..  33:862-871. 2014
  • Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes..  32:5388-5396. 2013
  • Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas..  32:3091-3100. 2013
  • TβRIII/β-arrestin2 regulates integrin α5β1 trafficking, function, and localization in epithelial cells..  32:1416-1427. 2013
  • REV3L 3'UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility..  32:242-250. 2013
  • EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase..  31:5132-5143. 2012
  • Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-induced inactivation..  31:2129-2139. 2012
  • Erythropoietin receptor contributes to melanoma cell survival in vivo..  31:1649-1660. 2012
  • β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression..  31:282-292. 2012
  • Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer..  31:213-225. 2012
  • Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells..  31:104-115. 2012
  • Inactivation of the von Hippel-Lindau tumor suppressor leads to selective expression of a human endogenous retrovirus in kidney cancer..  30:4697-4706. 2011
  • Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition..  30:3454-3467. 2011
  • IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation..  30:2558-2569. 2011
  • Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy..  30:2504-2513. 2011
  • Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis..  30:1855-1867. 2011
  • Akt1 deletion prevents lung tumorigenesis by mutant K-ras..  30:1812-1821. 2011
  • Negative regulation of the tumor suppressor p53 gene by microRNAs..  30:843-853. 2011
  • Epidermal growth factor receptor variant III mediates head and neck cancer cell invasion via STAT3 activation..  29:5135-5145. 2010
  • Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth..  29:4959-4970. 2010
  • Loss of type III transforming growth factor-beta receptor expression is due to methylation silencing of the transcription factor GATA3 in renal cell carcinoma..  29:2905-2915. 2010
  • A novel XPF -357A>C polymorphism predicts risk and recurrence of bladder cancer..  29:1920-1928. 2010
  • Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes..  29:1741-1752. 2010
  • Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity..  28:3837-3846. 2009
  • Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin..  28:3401-3411. 2009
  • A combinatorial mechanism for determining the specificity of E2F activation and repression..  28:2873-2881. 2009
  • Anchorage-independent cell growth signature identifies tumors with metastatic potential..  28:2796-2805. 2009
  • Hdm2 is regulated by K-Ras and mediates p53-independent functions in pancreatic cancer cells..  28:709-720. 2009
  • Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells..  28:209-218. 2009
  • Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling..  27:7235-7247. 2008
  • Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype..  27:6151-6163. 2008
  • TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation..  27:5348-5353. 2008
  • 1p36 is a preferential target of chromosome 1 deletions in astrocytic tumours and homozygously deleted in a subset of glioblastomas..  27:2097-2108. 2008
  • Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome..  27:1665-1676. 2008
  • U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia..  27:1536-1544. 2008