J Am Chem Soc

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  Publication Venue For

  • Characterization of a Radical SAM Oxygenase for the Ether Crosslinking in Darobactin Biosynthesis..  144:18876-18886. 2022
  • Mechanism of Reduction of an Aminyl Radical Intermediate in the Radical SAM GTP 3',8-Cyclase MoaA..  143:13835-13844. 2021
  • Environmental Effects on Guanine-Thymine Mispair Tautomerization Explored with Quantum Mechanical/Molecular Mechanical Free Energy Simulations..  142:11183-11191. 2020
  • Mechanism of Rate Acceleration of Radical C-C Bond Formation Reaction by a Radical SAM GTP 3',8-Cyclase..  142:9314-9326. 2020
  • Exposing Hidden High-Affinity RNA Conformational States..  142:907-921. 2020
  • NMR Chemical Exchange Measurements Reveal That N6-Methyladenosine Slows RNA Annealing..  141:19988-19993. 2019
  • The Elusive 5'-Deoxyadenosyl Radical: Captured and Characterized by Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopies..  141:12139-12146. 2019
  • Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis..  140:8634-8638. 2018
  • Direct NMR Evidence that Transient Tautomeric and Anionic States in dG·dT Form Watson-Crick-like Base Pairs..  139:4326-4329. 2017
  • Smelling Sulfur: Copper and Silver Regulate the Response of Human Odorant Receptor OR2T11 to Low-Molecular-Weight Thiols..  138:13281-13288. 2016
  • Modulating RNA Alignment Using Directional Dynamic Kinks: Application in Determining an Atomic-Resolution Ensemble for a Hairpin using NMR Residual Dipolar Couplings..  137:12954-12965. 2015
  • Chemoenzymatic Assembly of Bacterial Glycoconjugates for Site-Specific Orthogonal Labeling..  137:12446-12449. 2015
  • Conserved Residues Control Activation of Mammalian G Protein-Coupled Odorant Receptors..  137:8611-8616. 2015
  • Optical Control of CRISPR/Cas9 Gene Editing..  137:5642-5645. 2015
  • Noncanonical secondary structure stabilizes mitochondrial tRNA(Ser(UCN)) by reducing the entropic cost of tertiary folding..  137:3592-3599. 2015
  • C-Terminal glycine-gated radical initiation by GTP 3',8-cyclase in the molybdenum cofactor biosynthesis..  137:3352-3359. 2015
  • A chemically competent thiosulfuranyl radical on the Escherichia coli class III ribonucleotide reductase..  136:9001-9013. 2014
  • Ligand concentration regulates the pathways of coupled protein folding and binding..  136:822-825. 2014
  • Correction to "Enthalpic Signature of Methonium Desolvation Revealed in a Synthetic Host-Guest System Based on Cucurbit[7]uril"..  135:17650. 2013
  • Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases..  135:15536-15548. 2013
  • Chemical synthesis of highly congested gp120 V1V2 N-glycopeptide antigens for potential HIV-1-directed vaccines..  135:13113-13120. 2013
  • Storage of hydrogen spin polarization in long-lived 13C2 singlet order and implications for hyperpolarized magnetic resonance imaging..  135:9632-9635. 2013
  • Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer..  135:8585-8593. 2013
  • Characterizing the protonation state of cytosine in transient G·C Hoogsteen base pairs in duplex DNA..  135:6766-6769. 2013
  • Identification of a cyclic nucleotide as a cryptic intermediate in molybdenum cofactor biosynthesis..  135:7019-7032. 2013
  • A general method for constructing atomic-resolution RNA ensembles using NMR residual dipolar couplings: the basis for interhelical motions revealed..  135:5457-5466. 2013
  • Rapid protein global fold determination using ultrasparse sampling, high-dynamic range artifact suppression, and time-shared NOESY..  134:18619-18630. 2012
  • Development of a Grp94 inhibitor..  134:9796-9804. 2012
  • Probing transient Hoogsteen hydrogen bonds in canonical duplex DNA using NMR relaxation dispersion and single-atom substitution..  134:3667-3670. 2012
  • Equilibration of tyrosyl radicals (Y356•, Y731•, Y730•) in the radical propagation pathway of the Escherichia coli class Ia ribonucleotide reductase..  133:18420-18432. 2011
  • Sequence-specific B-DNA flexibility modulates Z-DNA formation..  133:2016-2018. 2011
  • A hot oxidant, 3-NO2Y122 radical, unmasks conformational gating in ribonucleotide reductase..  132:15368-15379. 2010
  • Site-specific incorporation of 3-nitrotyrosine as a probe of pKa perturbation of redox-active tyrosines in ribonucleotide reductase..  132:8385-8397. 2010
  • Using isotopic tools to dissect and quantitate parallel metabolic pathways..  132:6309-6311. 2010
  • Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors..  132:3164-3176. 2010
  • Extending the range of microsecond-to-millisecond chemical exchange detected in labeled and unlabeled nucleic acids by selective carbon R(1rho) NMR spectroscopy..  131:3818-3819. 2009
  • Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle..  130:15361-15373. 2008
  • Aqueous noncovalent functionalization and controlled near-surface carbon doping of multiwalled boron nitride nanotubes..  130:8144-8145. 2008
  • Dynamics of large elongated RNA by NMR carbon relaxation..  129:16072-16082. 2007
  • Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin..  129:15147-15155. 2007
  • Essential role of an active-site guanine in glmS ribozyme catalysis..  129:14858-14859. 2007