Genes Dev

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  Publication Venue For

  • WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma..  37:86-102. 2023
  • Single-molecule identification of the target RNAs of different RNA binding proteins simultaneously in cells..  36:1002-1015. 2022
  • ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD..  36:618-633. 2022
  • Killing SCLC: insights into how to target a shapeshifting tumor..  36:241-258. 2022
  • ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes..  35:1461-1474. 2021
  • Cold-responsive adipocyte progenitors couple adrenergic signaling to immune cell activation to promote beige adipocyte accrual..  35:1333-1338. 2021
  • Disruption of origin chromatin structure by helicase activation in the absence of DNA replication..  35:1339-1355. 2021
  • ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer..  35:847-869. 2021
  • ZCCHC8, the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation..  33:1381-1396. 2019
  • Dissection of the molecular circuitry controlling virulence in Francisella tularensis..  31:1549-1560. 2017
  • Structures of partition protein ParA with nonspecific DNA and ParB effector reveal molecular insights into principles governing Walker-box DNA segregation..  31:481-492. 2017
  • Sorting out adipocyte precursors and their role in physiology and disease..  31:127-140. 2017
  • IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3..  30:1837-1851. 2016
  • DNA replication origins-where do we begin?.  30:1683-1697. 2016
  • O-GlcNAcylation of master growth repressor DELLA by SECRET AGENT modulates multiple signaling pathways in Arabidopsis..  30:164-176. 2016
  • Cellular projections from sensory hair cells form polarity-specific scaffolds during synaptogenesis..  29:1087-1094. 2015
  • Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis..  29:451-464. 2015
  • Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly..  29:212-224. 2015
  • The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair..  28:2726-2738. 2014
  • Chromosome rearrangements via template switching between diverged repeated sequences..  28:2394-2406. 2014
  • The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2..  28:1929-1939. 2014
  • Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration..  28:995-1004. 2014
  • RIP3: a molecular switch for necrosis and inflammation..  27:1640-1649. 2013
  • Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target..  27:197-210. 2013
  • Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling..  26:2271-2285. 2012
  • Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways..  26:2154-2168. 2012
  • Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression..  25:1384-1398. 2011
  • BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair..  25:350-362. 2011
  • Sex-induced silencing defends the genome of Cryptococcus neoformans via RNAi..  24:2566-2582. 2010
  • CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1..  24:2303-2316. 2010
  • Error-prone polyploid mitosis during normal Drosophila development..  24:2294-2302. 2010
  • 5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage..  24:2146-2156. 2010
  • The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery..  24:2013-2018. 2010
  • The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin..  24:1418-1433. 2010
  • Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer..  24:837-852. 2010
  • Conserved nucleosome positioning defines replication origins..  24:748-753. 2010
  • Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells..  24:659-669. 2010
  • miR-19 is a key oncogenic component of mir-17-92..  23:2839-2849. 2009
  • Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal..  23:2521-2536. 2009
  • Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A..  23:1665-1676. 2009
  • N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma..  23:157-170. 2009