Plos Pathog

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  Publication Venue For

  • Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge..  16:e1008764. 2020
  • Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5..  16:e1008327. 2020
  • Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens..  16:e1008665. 2020
  • Optimal priming of poxvirus vector (NYVAC)-based HIV vaccine regimens for T cell responses requires three DNA injections. Results of the randomized multicentre EV03/ANRS VAC20 Phase I/II Trial..  16:e1008522. 2020
  • Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium..  16:e1008553. 2020
  • Battling brain-eating amoeba: Enigmas surrounding immunity to Naegleria fowleri..  16:e1008406. 2020
  • Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type..  16:e1008531. 2020
  • Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition..  16:e1008377. 2020
  • Maternal gatekeepers: How maternal antibody Fc characteristics influence passive transfer and infant protection..  16:e1008303. 2020
  • Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies..  16:e1008083. 2020
  • Intrahost cytomegalovirus population genetics following antibody pretreatment in a monkey model of congenital transmission..  16:e1007968. 2020
  • ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type..  15:e1008121. 2019
  • Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans..  15:e1008165. 2019
  • Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies..  15:e1008200. 2019
  • Novel and emerging sources of Clostridioides difficile infection..  15:e1008125. 2019
  • The pandemic Escherichia coli sequence type 131 strain is acquired even in the absence of antibiotic exposure..  15:e1008162. 2019
  • Influenza viruses that require 10 genomic segments as antiviral therapeutics..  15:e1008098. 2019
  • Correction: Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype..  15:e1008070. 2019
  • Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance..  15:e1008077. 2019
  • Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies..  15:e1008026. 2019
  • Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage..  15:e1008005. 2019
  • Helicobacter pylori and colorectal cancer-A bacterium going abroad?.  15:e1007861. 2019
  • Primary infection with dengue or Zika virus does not affect the severity of heterologous secondary infection in macaques..  15:e1007766. 2019
  • Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription..  15:e1007988. 2019
  • Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype..  15:e1007945. 2019
  • Born to sweet delight: Using natural models of malaria protection to understand and neutralize P. falciparum pathogenesis..  15:e1007770. 2019
  • Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies..  15:e1007646. 2019
  • Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization..  15:e1007381. 2019
  • The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein..  15:e1007163. 2019
  • Barrett's esophagus and esophageal cancer: Links to microbes and the microbiome..  14:e1007384. 2018
  • Innate antimicrobial immunity in the skin: A protective barrier against bacteria, viruses, and fungi..  14:e1007353. 2018
  • HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies..  14:e1007431. 2018
  • NLRC3 negatively regulates CD4+ T cells and impacts protective immunity during Mycobacterium tuberculosis infection..  14:e1007266. 2018
  • Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?.  14:e1007161. 2018
  • Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV..  14:e1007159. 2018
  • Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition..  14:e1007126. 2018
  • Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation..  14:e1007024. 2018
  • Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection..  14:e1007057. 2018
  • Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins..  14:e1006986. 2018
  • Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators..  14:e1006982. 2018
  • Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques..  14:e1007104. 2018
  • Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma..  14:e1006944. 2018
  • Pearls collections: What we can learn about infectious disease and cancer..  14:e1006915. 2018
  • Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections..  14:e1006860. 2018
  • Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication..  14:e1006919. 2018
  • Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques..  14:e1006913. 2018
  • A single gp120 residue can affect HIV-1 tropism in macaques..  13:e1006572. 2017
  • Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization..  13:e1006641. 2017
  • Genetic and epigenetic engines of diversity in pathogenic microbes..  13:e1006468. 2017
  • Yes, research matters..  13:e1006420. 2017
  • Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission..  13:e1006535. 2017
  • Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection..  13:e1006510. 2017
  • Revisiting the concept of a cytopathic viral infection..  13:e1006409. 2017
  • Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques..  13:e1006378. 2017
  • RNA modifications go viral..  13:e1006188. 2017
  • Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial..  13:e1006182. 2017
  • The effective rate of influenza reassortment is limited during human infection..  13:e1006203. 2017
  • Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting..  13:e1006148. 2017
  • The Impact of the Gut Microbiota on Humoral Immunity to Pathogens and Vaccination in Early Infancy..  12:e1005997. 2016
  • The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation..  12:e1006035. 2016
  • The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence..  12:e1006001. 2016
  • Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs..  12:e1005949. 2016
  • Calcineurin Targets Involved in Stress Survival and Fungal Virulence..  12:e1005873. 2016
  • Impact of Microbiota on Resistance to Ocular Pseudomonas aeruginosa-Induced Keratitis..  12:e1005855. 2016
  • Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C..  12:e1005864. 2016
  • Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses..  12:e1005817. 2016
  • Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection..  12:e1005805. 2016
  • Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization..  12:e1005742. 2016
  • The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease..  12:e1005680. 2016
  • Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection..  12:e1005520. 2016
  • The March towards a Vaccine for Congenital CMV: Rationale and Models..  12:e1005355. 2016
  • Impact of Bacterial and Human Genetic Variation on Staphylococcus aureus Infections..  12:e1005330. 2016
  • An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses..  11:e1005082. 2015
  • Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques..  11:e1005042. 2015
  • Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIVmac251 Rectal Challenge..  11:e1005101. 2015
  • Extracellular Virions: The Advance Guard of Poxvirus Infections..  11:e1004904. 2015
  • EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival..  11:e1004979. 2015
  • Successes and Challenges on the Road to Cure Hepatitis C..  11:e1004854. 2015
  • The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T Cells..  11:e1004928. 2015
  • Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site..  11:e1004932. 2015
  • Impaired systemic tetrahydrobiopterin bioavailability and increased dihydrobiopterin in adult falciparum malaria: association with disease severity, impaired microvascular function and increased endothelial activation..  11:e1004667. 2015
  • Impaired systemic tetrahydrobiopterin bioavailability and increased oxidized biopterins in pediatric falciparum malaria: association with disease severity..  11:e1004655. 2015
  • To be or not IIb: a multi-step process for Epstein-Barr virus latency establishment and consequences for B cell tumorigenesis..  11:e1004656. 2015
  • XRN1 stalling in the 5' UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability..  11:e1004708. 2015
  • Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses..  11:e1004658. 2015
  • Implication of gut microbiota in nonalcoholic fatty liver disease..  11:e1004559. 2015
  • On the Discovery of TOR As the Target of Rapamycin..  11:e1005245. 2015
  • Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal..  10:e1004285. 2014
  • G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA..  10:e1004242. 2014
  • Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis..  10:e1004149. 2014
  • HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development..  10:e1004073. 2014
  • T cell inactivation by poxviral B22 family proteins increases viral virulence..  10:e1004123. 2014
  • TCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeys..  10:e1004069. 2014
  • Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques..  10:e1003958. 2014
  • Clustering of pattern recognition receptors for fungal detection..  10:e1003873. 2014
  • Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response..  10:e1003981. 2014
  • The Chlamydia trachomatis type III secretion chaperone Slc1 engages multiple early effectors, including TepP, a tyrosine-phosphorylated protein required for the recruitment of CrkI-II to nascent inclusions and innate immune signaling..  10:e1003954. 2014
  • Are we there yet? Recent progress in the molecular diagnosis and novel antifungal targeting of Aspergillus fumigatus and invasive aspergillosis..  9:e1003642. 2013
  • Unisexual reproduction drives evolution of eukaryotic microbial pathogens..  9:e1003674. 2013
  • Self and non-self discrimination of intracellular membranes by the innate immune system..  9:e1003538. 2013
  • Quantitative models of the dose-response and time course of inhalational anthrax in humans..  9:e1003555. 2013
  • LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells..  9:e1003357. 2013
  • Generators of phenotypic diversity in the evolution of pathogenic microorganisms..  9:e1003181. 2013
  • Brain inositol is a novel stimulator for promoting Cryptococcus penetration of the blood-brain barrier..  9:e1003247. 2013
  • Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides..  9:e1003625. 2013
  • Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis..  9:e1003358. 2013
  • Hemoglobinopathies: slicing the Gordian knot of Plasmodium falciparum malaria pathogenesis..  9:e1003327. 2013
  • How do viruses avoid inhibition by endogenous cellular microRNAs?.  9:e1003694. 2013
  • IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins..  9:e1003414. 2013
  • Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus..  9:e1003564. 2013
  • Understanding human variation in infectious disease susceptibility through clinical and cellular GWAS..  9:e1003424. 2013
  • Population genetic analyses reveal the African origin and strain variation of Cryptococcus neoformans var. grubii..  8:e1002495. 2012
  • Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape..  8:e1002721. 2012
  • Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing..  8:e1002880. 2012
  • Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata..  8:e1002718. 2012
  • How to make it in the urinary tract: a tutorial by Escherichia coli..  8:e1002907. 2012
  • Macrophage activation associated with chronic murine cytomegalovirus infection results in more severe experimental choroidal neovascularization..  8:e1002671. 2012
  • Malassezia fungi are specialized to live on skin and associated with dandruff, eczema, and other skin diseases..  8:e1002701. 2012
  • Molecular determinants and dynamics of hepatitis C virus secretion..  8:e1002466. 2012
  • Parallels in intercellular communication in oomycete and fungal pathogens of plants and humans..  8:e1003028. 2012
  • Structural mechanism of trimeric HIV-1 envelope glycoprotein activation..  8:e1002797. 2012
  • The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18..  8:e1002992. 2012
  • The viral and cellular microRNA targetome in lymphoblastoid cell lines..  8:e1002484. 2012
  • Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7..  8:e1002686. 2012
  • Zebrafish: a see-through host and a fluorescent toolbox to probe host-pathogen interaction..  8:e1002349. 2012
  • Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner..  7:e1002364. 2011
  • Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis..  7:e1002311. 2011
  • A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients..  7:e1002205. 2011
  • Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies..  7:e1002200. 2011
  • Exhausted CD8 T cells downregulate the IL-18 receptor and become unresponsive to inflammatory cytokines and bacterial co-infections..  7:e1002273. 2011
  • Exploiting and subverting Tor signaling in the pathogenesis of fungi, parasites, and viruses..  7:e1002269. 2011
  • Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections..  7:e1002209. 2011
  • Structure of herpes simplex virus glycoprotein D bound to the human receptor nectin-1..  7:e1002277. 2011
  • Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion..  7:e1002170. 2011
  • Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes..  7:e1002141. 2011
  • Unique evolution of the UPR pathway with a novel bZIP transcription factor, Hxl1, for controlling pathogenicity of Cryptococcus neoformans..  7:e1002177. 2011
  • Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections..  7:e1001346. 2011
  • Sporangiospore size dimorphism is linked to virulence of Mucor circinelloides..  7:e1002086. 2011
  • Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection..  7:e1001273. 2011
  • A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus..  7:e1001294. 2011
  • Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure..  6:e1001249. 2010
  • Escherichia coli global gene expression in urine from women with urinary tract infection..  6:e1001187. 2010
  • Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses..  6:e1001088. 2010
  • PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90..  6:e1001069. 2010
  • Cryptococcal cell morphology affects host cell interactions and pathogenicity..  6:e1000953. 2010
  • High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men..  6:e1000890. 2010
  • Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection..  6:e1000893. 2010
  • Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States..  6:e1000850. 2010
  • Increased asymmetric dimethylarginine in severe falciparum malaria: association with impaired nitric oxide bioavailability and fatal outcome..  6:e1000868. 2010
  • A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection..  6:e1000817. 2010
  • MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference..  6:e1000820. 2010
  • Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells..  6:e1000798. 2010
  • Five questions about viruses and microRNAs..  6:e1000787. 2010
  • Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule..  6:e1000776. 2010
  • Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection..  6. 2010
  • Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States..  6. 2010
  • High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men..  6:e1000890. 2010
  • Inhibition of adaptive immune responses leads to a fatal clinical outcome in SIV-infected pigtailed macaques but not vervet African green monkeys..  5:e1000691. 2009
  • RNA interference and single particle tracking analysis of hepatitis C virus endocytosis..  5:e1000702. 2009
  • The Chlamydia type III secretion system C-ring engages a chaperone-effector protein complex..  5:e1000579. 2009
  • Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin..  5:e1000532. 2009
  • HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC..  5:e1000414. 2009
  • Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses..  5:e1000333. 2009
  • A critical role for CD8 T cells in a nonhuman primate model of tuberculosis..  5:e1000392. 2009
  • The protein kinase Tor1 regulates adhesin gene expression in Candida albicans..  5:e1000294. 2009
  • Diploids in the Cryptococcus neoformans serotype A population homozygous for the alpha mating type originate via unisexual mating..  5:e1000283. 2009
  • Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection..  4:e1000236. 2008
  • A two-phase innate host response to alphavirus infection identified by mRNP-tagging in vivo..  3:e199. 2007
  • Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa..  3:e114. 2007
  • A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells..  3:e60. 2007
  • A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells..  3:e60. 2007
  • A genomic approach to identify regulatory nodes in the transcriptional network of systemic acquired resistance in plants..  2. 2006
  • Retroviral DNA integration: viral and cellular determinants of target-site selection..  2:e60. 2006
  • Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed..  2:e23. 2006
  • Commensal-Induced Regulatory T Cells Mediate Protection against Pathogen-Stimulated NF-κB Activation.  4:e1000112-e1000112.
  • Correction: Thy1+Nk Cells from Vaccinia Virus-Primed Mice Confer Protection against Vaccinia Virus Challenge in the Absence of Adaptive Lymphocytes.  7.
  • Crystal Structure of Reovirus Attachment Protein σ1 in Complex with Sialylated Oligosaccharides.  7:e1002166-e1002166.
  • Type III Effector Activation via Nucleotide Binding, Phosphorylation, and Host Target Interaction.  3:e48-e48.