Chemistry & Biology

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  Publication Venue For

  • Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70..  21:1648-1659. 2014
  • Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection..  21:977-987. 2014
  • Probing the coagulation pathway with aptamers identifies combinations that synergistically inhibit blood clot formation..  21:935-944. 2014
  • Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells..  20:1187-1197. 2013
  • TR-FRET-based duplex immunoassay reveals an inverse correlation of soluble and aggregated mutant huntingtin in huntington's disease..  19:264-275. 2012
  • Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design..  18:38-47. 2011
  • Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90..  17:686-694. 2010
  • Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase..  16:181-192. 2009