Sci Transl Med
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Publication Venue For
- Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial.. 15:eade9078. 2023
- Rescue of glutaric aciduria type I in mice by liver-directed therapies.. 15:eadf4086. 2023
- Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later.. 15:eadd6383. 2023
- Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models.. 15:eabn5649. 2023
- CD200+ cytotoxic T lymphocytes in the tumor microenvironment are crucial for efficacious anti-PD-1/PD-L1 therapy.. 15:eabn5029. 2023
- Persistent post-COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium.. 14:eadd0484. 2022
- Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation.. 14:eabg8577. 2022
- Tumor-intrinsic NLRP3-HSP70-TLR4 axis drives premetastatic niche development and hyperprogression during anti-PD-1 immunotherapy.. 14:eabq7019. 2022
- Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment.. 14:eabo3445. 2022
- TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure.. 14:eabm3565. 2022
- Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection.. 14:eabo5598. 2022
- MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT.. 14:eabj2829. 2022
- Acute inflammatory response via neutrophil activation protects against the development of chronic pain.. 14:eabj9954. 2022
- A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk.. 14:eabj9625. 2022
- Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells.. 14:eabc7480. 2022
- Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b.. 14:eabh3831. 2022
- Translating science to medicine: The case for physician-scientists.. 14:eabg7852. 2022
- A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.. 14:eabj7125. 2022
- A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus.. 14:eabl7430. 2022
- A small molecule targeting ALOX12-ACC1 ameliorates nonalcoholic steatohepatitis in mice and macaques.. 13:eabg8116. 2021
- Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis.. 13:eabg8117. 2021
- Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses.. 13:eabi7428. 2021
- Pregnancy influences immune responses to SARS-CoV-2.. 13:eabm2070. 2021
- The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia.. 13. 2021
- Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury.. 13. 2021
- Ultrasensitive point-of-care immunoassay for secreted glycoprotein detects Ebola infection earlier than PCR.. 13. 2021
- Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.. 13. 2021
- Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1.. 12. 2020
- Antibody binding to native cytomegalovirus glycoprotein B predicts efficacy of the gB/MF59 vaccine in humans.. 12. 2020
- Prospects for a safe COVID-19 vaccine.. 12. 2020
- Achieving healthy human longevity: A global grand challenge.. 12. 2020
- Global approaches to genomic medicine implementation.. 12. 2020
- An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs.. 12. 2020
- Anti-PD-1 treatment impairs opioid antinociception in rodents and nonhuman primates.. 12. 2020
- APOE genotype regulates pathology and disease progression in synucleinopathy.. 12. 2020
- Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer.. 11. 2019
- Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.. 11. 2019
- Prospective clinical testing and experimental validation of the Pediatric Sepsis Biomarker Risk Model.. 11. 2019
- Multiple roles for HIV broadly neutralizing antibodies.. 11. 2019
- Immune correlates of the Thai RV144 HIV vaccine regimen in South Africa.. 11. 2019
- MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21.. 11. 2019
- A multimodality test to guide the management of patients with a pancreatic cyst.. 11. 2019
- Translational impact of NIH-funded nonhuman primate research in transplantation.. 11. 2019
- Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease.. 11. 2019
- Bioengineered human acellular vessels recellularize and evolve into living blood vessels after human implantation.. 11. 2019
- Loss of HDAC3 results in nonreceptive endometrium and female infertility.. 11. 2019
- Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.. 10. 2018
- Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7.. 10. 2018
- Health and societal implications of medical and technological advances.. 10. 2018
- In utero priming of highly functional effector T cell responses to human malaria.. 10. 2018
- Finding useful biomarkers for Parkinson's disease.. 10. 2018
- LRRK2 activation in idiopathic Parkinson's disease.. 10. 2018
- Neutrophils cause obstruction of eyelid sebaceous glands in inflammatory eye disease in mice.. 10. 2018
- Transcriptional signature primes human oral mucosa for rapid wound healing.. 10. 2018
- Transgelin-2 as a therapeutic target for asthmatic pulmonary resistance.. 10. 2018
- Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice.. 10. 2018
- Rescue of Pompe disease in mice by AAV-mediated liver delivery of secretable acid α-glucosidase.. 9. 2017
- Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia.. 9. 2017
- Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs.. 9. 2017
- When they go low, we go high.. 9. 2017
- Working memory: The real VIP.. 9. 2017
- The neural substrates of super memory.. 9. 2017
- Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.. 9. 2017
- Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.. 9. 2017
- Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.. 9. 2017
- Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2.. 9. 2017
- Suppressing oncogenic transcription with a little healthy competition.. 9. 2017
- Optimized temporal pattern of brain stimulation designed by computational evolution.. 9. 2017
- PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation.. 8:369ra175. 2016
- An EXITS strategy for decreasing cancer risk in women.. 8:368ec197. 2016
- Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition.. 8:366ra164. 2016
- Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone.. 8:340ra73. 2016
- Treating the enigmatic "exceptional responders" as patients with undiagnosed diseases.. 8:340ed8. 2016
- Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.. 8:336ra62. 2016
- Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology.. 8:324ps5. 2016
- A cybersecurity primer for translational research.. 8:322ps2. 2016
- CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.. 8:322ra10. 2016
- Host gene expression classifiers diagnose acute respiratory illness etiology.. 8:322ra11. 2016
- A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer.. 8:320ra4. 2016
- Pacemaker-induced transient asynchrony suppresses heart failure progression.. 7:319ra207. 2015
- Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker.. 7:316ra193. 2015
- Immune correlates of vaccine protection against HIV-1 acquisition.. 7:310rv7. 2015
- A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo.. 7:302ra136. 2015
- HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition.. 7:296ra112. 2015
- Global implementation of genomic medicine: We are not alone.. 7:290ps13. 2015
- Research in academic medical centers: two threats to sustainable support.. 7:289fs22. 2015
- The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors.. 7:287ra72. 2015
- Tumor cells, but not endothelial cells, mediate eradication of primary sarcomas by stereotactic body radiation therapy.. 7:278ra34. 2015
- Noninvasive brain-computer interface enables communication after brainstem stroke.. 6:257re7. 2014
- A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation.. 6:256ra136. 2014
- Reining in radiation injury: HIF2α in the gut.. 6:236fs20. 2014
- Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination.. 6:228ra39. 2014
- Detection of circulating tumor DNA in early- and late-stage human malignancies.. 6:224ra24. 2014
- Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR.. 5:212ra162. 2013
- A brain-machine interface enables bimanual arm movements in monkeys.. 5:210ra154. 2013
- A host-based RT-PCR gene expression signature to identify acute respiratory viral infection.. 5:203ra126. 2013
- Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.. 5:197ra101. 2013
- An integrated clinico-metabolomic model improves prediction of death in sepsis.. 5:195ra95. 2013
- CaMKII is essential for the proasthmatic effects of oxidation.. 5:195ra97. 2013
- Genomic medicine: a decade of successes, challenges, and opportunities.. 5:189sr4. 2013
- Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.. 5:181re1. 2013
- Methylation subtypes and large-scale epigenetic alterations in gastric cancer.. 4:156ra140. 2012
- Thoroughly modern risk prediction?. 4:131fs10. 2012
- Chimerism and tolerance without GVHD or engraftment syndrome in HLA-mismatched combined kidney and hematopoietic stem cell transplantation.. 4:124ra28. 2012
- Preclinical and clinical evaluation of intraductally administered agents in early breast cancer.. 3:106ra108. 2011
- The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins.. 3:106ra106. 2011
- Academic medical centers: ripe for rapid-learning personalized health care.. 3:101cm27. 2011
- Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.. 3:101ra93. 2011
- Biomedical innovation: a risky business at risk.. 3:96cm23. 2011
- Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality.. 3:94ra70. 2011
- Defending male fertility.. 3:92ps31. 2011
- Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development.. 3:92ra66. 2011
- Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys.. 3:81ra36. 2011
- Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss.. 3:80re2. 2011
- HIV-1 vaccines and adaptive trial designs.. 3:79ps13. 2011
- CD44-SLC1A2 gene fusions in gastric cancer.. 3:77ra30. 2011
- β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix.. 3:74ra23. 2011
- Pump-probe imaging differentiates melanoma from melanocytic nevi.. 3:71ra15. 2011
- Readily available tissue-engineered vascular grafts.. 3:68ra9. 2011
- Opening up to precompetitive collaboration.. 2:52cm26. 2010
- PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.. 2:52ra73. 2010
- Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability.. 2:49ra68. 2010
- Blood gene expression signatures predict invasive candidiasis.. 2:21ra17. 2010
- A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation.. 1:1ra1. 2009