Calcimycin

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  Subject Areas on Research

  • 8-ISO-PGF2alpha production by alveolar macrophages exposed to hyperoxia. 
  • Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms. 
  • Alpha-tocopheryl succinate protects hepatocytes from chemical-induced toxicity under physiological calcium conditions. 
  • Arachidonic acid metabolism in cultured aortic endothelial cells. Effect of cAMP and 3-isobutyl-1-methylxanthine. 
  • Chemoattractant-elicited alterations of cAMP levels in human polymorphonuclear leukocytes require a Ca2+-dependent mechanism which is independent of transmembrane activation of adenylate cyclase. 
  • Cortical reorganization following fertilization of sea urchin eggs: sensitivity to cytochalasin B. 
  • Coupling endoplasmic reticulum stress to cell death program in isolated human pancreatic islets: effects of gene transfer of Bcl-2. 
  • Deencryption of cellular tissue factor is independent of its cytoplasmic domain. 
  • Depletion of arterial L-arginine causes reversible tolerance to endothelium-dependent relaxation. 
  • Differential platelet-activating factor synthesis by monocytes and polymorphonuclear leukocytes from subjects with localized aggressive periodontitis. 
  • Divalent cation activation of galactosyltransferase in native mammary Golgi vesicles. 
  • Effect of vasoactive intestinal peptide (VIP) on cytokine production and expression of VIP receptors in thymocyte subsets. 
  • Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium. 
  • Evaluation of phospholipase C and D activity in stimulated human neutrophils using a phosphono analog of choline phosphoglyceride. 
  • Evidence against formation of A23187 dimers and oligomers in solution: photo-induced degradation of Ionophore A23187. 
  • Follicle-stimulating hormone activation of glycogen phosphorylase in the Sertoli cell-enriched rat testis. 
  • Glycogenolytic effects of the calcium ionophore A23187, but not of vasopressin or angiotensin, in foetal-rat hepatocytes. 
  • In vitro inhibition of murine IFN gamma production by phosphorothioate deoxyguanosine oligomers. 
  • Ion fluxes and differentiation in transformed cell lines. 
  • Ionophore 4-BrA23187 transports Zn2+ and Mn2+ with high selectivity over Ca2+. 
  • Mechanism and specificity of lanthanide series cation transport by ionophores A23187, 4-BrA23187, and ionomycin. 
  • Mechanism of bradykinin-stimulated prostacyclin synthesis in porcine aortic endothelial cells. 
  • Mechanisms of nonimmunological histamine and tryptase release from human cutaneous mast cells. 
  • Mechanisms of regulating the respiratory burst in leukocytes. 
  • Membrane protein mediation of thromboxane A2-induced platelet aggregation. 
  • Microvilli elongate in response to hydrogen peroxide and to perturbations of intracellular calcium. 
  • Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors. 
  • Pharmacologic activation of the human coronary microcirculation in vitro: endothelium-dependent dilation and differential responses to acetylcholine. 
  • Phenotypic dissections of the Blastocladiella emersonii zoospore's developmental choice. 
  • Platelet activation in patients with thrombotic thrombocytopenic purpura. 
  • Platelet-activating factor induces tyrosine phosphorylation in human neutrophils. 
  • Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506. 
  • Progesterone protects fetal chorion and maternal decidua cells from calcium-induced death. 
  • Regulation of platelet-activating factor synthesis in human neutrophils by MAP kinases. 
  • Requirement for metalloendoprotease in exocytosis: evidence in mast cells and adrenal chromaffin cells. 
  • Role of alpha 1 adrenoceptors in the turnover of phosphatidylinositol and of alpha 2 adrenoceptors in the regulation of cyclic AMP accumulation in hamster adipocytes. 
  • Short-term regulation of Na+/K+ adenosine triphosphatase by recombinant human serotonin 5-HT1A receptor expressed in HeLa cells. 
  • Superoxide production, risk factors, and endothelium-dependent relaxations in human internal mammary arteries. 
  • T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+. 
  • The NADPH oxidase of human polymorphonuclear leukocytes. Evidence for regulation by multiple signals. 
  • The role of calcium in the regulation of prostacyclin synthesis by porcine aortic endothelial cells. 
  • Thiopyrano[2,3,4-cd]indoles as 5-lipoxygenase inhibitors: synthesis, biological profile, and resolution of 2-[2-[1-(4-chlorobenzyl)-4-methyl-6-[(5-phenylpyridin-2-yl)methoxy]-4,5 -dihydro-1H-thiopyrano[2,3,4-cd]indol-2-yl]ethoxy]butanoic acid. 
  • Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase. 
  • Tissue factor de-encryption: ionophore treatment induces changes in tissue factor activity by phosphatidylserine-dependent and -independent mechanisms. 
  • Transport properties of the calcium ionophore ETH-129.