Alarmins

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  Subject Areas on Research

  • After 62 years of regulating immunity, dexamethasone meets COVID-19. 
  • Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction. 
  • Damage- and pathogen-associated molecular patterns play differential roles in late mortality after critical illness. 
  • Damage-Associated Molecular Patterns Induce Inflammatory Injury During Machine Preservation of the Liver: Potential Targets to Enhance a Promising Technology. 
  • Divergent Roles of Epithelium-Derived Alarmins in Notch Signaling-Deficient Skin. 
  • Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness: A Systematic Review. 
  • Immunothrombotic Activity of Damage-Associated Molecular Patterns and Extracellular Vesicles in Secondary Organ Failure Induced by Trauma and Sterile Insults. 
  • Inflammation and thrombosis: roles of neutrophils, platelets and endothelial cells and their interactions in thrombus formation during sepsis. 
  • Neuroinflammation after surgery: from mechanisms to therapeutic targets. 
  • Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis. 
  • Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis. 
  • Targeting DAMPs with nucleic acid scavengers to treat lupus. 
  • The Alarmin Properties of DNA and DNA-associated Nuclear Proteins. 
  • The Cutaneous Wound Innate Immunological Microenvironment. 
  • Toll-like receptor activation as a biomarker in traumatically injured patients. 
  • Using oncolytic viruses to ignite the tumour immune microenvironment in bladder cancer.