ADAMTS5 Protein

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  Subject Areas on Research

  • ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression. 
  • Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican. 
  • Modulating hedgehog signaling can attenuate the severity of osteoarthritis. 
  • Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage.