Signaling Lymphocytic Activation Molecule Family
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Subject Areas on Research
- 2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis.
- Cutting edge: trimolecular interaction of TCR with MHC class II and bacterial superantigen shows a similar affinity to MHC:peptide ligands.
- Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection.