Autophagy-Related Proteins

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  Subject Areas on Research

  • A family of ubiquitin-like proteins binds the ATPase domain of Hsp70-like Stch. 
  • BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters. 
  • E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I. 
  • Editorial: TRPV1: how thymocytes sense stress and respond with autophagy. 
  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. 
  • HDAC4 promotes Pax7-dependent satellite cell activation and muscle regeneration. 
  • Increases in miR-124-3p in Microglial Exosomes Confer Neuroprotective Effects by Targeting FIP200-Mediated Neuronal Autophagy Following Traumatic Brain Injury. 
  • Lack of association between UBQLN1 and Alzheimer disease. 
  • Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction. 
  • Metabolic-stress-induced rearrangement of the 14-3-3ζ interactome promotes autophagy via a ULK1- and AMPK-regulated 14-3-3ζ interaction with phosphorylated Atg9. 
  • Noncanonical autophagy in dermal dendritic cells mediates immunosuppressive effects of UV exposure. 
  • Nonselective autophagy reduces mitochondrial content during starvation in Caenorhabditis elegans. 
  • Partners in anti-crime: how interferon-inducible GTPases and autophagy proteins team up in cell-intrinsic host defense. 
  • Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size. 
  • Potentially Functional Variants of ATG16L2 Predict Radiation Pneumonitis and Outcomes in Patients with Non-Small Cell Lung Cancer after Definitive Radiotherapy. 
  • Role of autophagy genetic variants for the risk of Candida infections. 
  • Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB. 
  • The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance. 
  • The carboxyl-terminal amino acids render pro-human LC3B migration similar to lipidated LC3B in SDS-PAGE. 
  • The ubiquilin 1 gene and Alzheimer's disease. 
  • Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians. 
  • Transiently expressed ATG16L1 inhibits autophagosome biogenesis and aberrantly targets RAB11-positive recycling endosomes. 
  • WIPI1 is a conserved mediator of right ventricular failure.