NLR Family, Pyrin Domain-Containing 3 Protein
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Subject Areas on Research
- A noncanonical function of cGAMP in inflammasome priming and activation.
- Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation.
- An NLRP3 Mutation Causes Arthropathy and Osteoporosis in Humanized Mice.
- An interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damage.
- Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β.
- Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells.
- Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P.
- Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1β activation.
- Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.
- Hyaluronan activation of the Nlrp3 inflammasome contributes to the development of airway hyperresponsiveness.
- IKKα negatively regulates ASC-dependent inflammasome activation.
- Immune activation by histones: plusses and minuses in inflammation.
- Inflammasome activation in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE).
- Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation.
- Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.
- Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation.
- NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation.
- NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis.
- NLRP3/IL-1β mediates denervation during bladder outlet obstruction in rats.
- Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation.
- The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy.
- The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.
- The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy.
- The NLRP3 Inflammasome Mediates Inflammation Produced by Bladder Outlet Obstruction.
- The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer.
- The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.
- The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.
- The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells).
- The role of interferon-β in the treatment of multiple sclerosis and experimental autoimmune encephalomyelitis - in the perspective of inflammasomes.
- Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation.
- [NLRP3 inflammasome and multiple sclerosis/EAE].