NLR Family, Pyrin Domain-Containing 3 Protein
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Subject Areas on Research
- A licence to kill during inflammation.
- A noncanonical function of cGAMP in inflammasome priming and activation.
- A possible mechanism underlying mood disorders associated with LUTS: Chronic bladder outlet obstruction causes NLRP3-dependent inflammation in the hippocampus and depressive behavior in rats.
- A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy.
- Activation of the NLRP3 inflammasome by intracellular poly I:C.
- Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation.
- An NLRP3 Mutation Causes Arthropathy and Osteoporosis in Humanized Mice.
- An interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damage.
- Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome.
- Association of CARD8 Activating Polymorphism With Bone Erosion in Cholesteatoma Patients.
- Bladder decompensation and reduction in nerve density in a rat model of chronic bladder outlet obstruction are attenuated with the NLRP3 inhibitor glyburide.
- Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β.
- Caspase-1-induced pyroptotic cell death.
- Caspase-11 interaction with NLRP3 potentiates the noncanonical activation of the NLRP3 inflammasome.
- Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2.
- Cyclophosphamide-induced cystitis results in NLRP3-mediated inflammation in the hippocampus and symptoms of depression in rats.
- Damage-Associated Molecular Patterns Induce Inflammatory Injury During Machine Preservation of the Liver: Potential Targets to Enhance a Promising Technology.
- Diabetic bladder dysfunction progresses from an overactive to an underactive phenotype in a type-1 diabetic mouse model (Akita female mouse) and is dependent on NLRP3.
- Down with doublespeak: NAIP/NLRC4 inflammasomes get specific.
- Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells.
- Endothelial PINK1 mediates the protective effects of NLRP3 deficiency during lethal oxidant injury.
- Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P.
- Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1β activation.
- Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.
- Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation.
- IKKα negatively regulates ASC-dependent inflammasome activation.
- Immune activation by histones: plusses and minuses in inflammation.
- Induction of Neuroinflammation and Neurotoxicity by Synthetic Hemozoin.
- Inflammasome activation in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE).
- Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation.
- Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.
- Just say NO to NLRP3.
- MCC950, a selective NLPR3 inflammasome inhibitor, improves neurologic function and survival after cardiac arrest and resuscitation.
- Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation.
- Mechanisms of NOD-like receptor-associated inflammasome activation.
- Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation.
- Mitochondrial Oxidative Phosphorylation Complex Regulates NLRP3 Inflammasome Activation and Predicts Patient Survival in Nasopharyngeal Carcinoma.
- Mitochondrial ROS and NLRP3 inflammasome in acute ozone-induced murine model of airway inflammation and bronchial hyperresponsiveness.
- Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection.
- NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation.
- NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis.
- NLRP3/IL-1β mediates denervation during bladder outlet obstruction in rats.
- Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5.
- Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production.
- Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation.
- Roles of mitochondrial ROS and NLRP3 inflammasome in multiple ozone-induced lung inflammation and emphysema.
- Specialized proresolution mediators in the bladder: annexin-A1 normalizes inflammation and bladder dysfunction during bladder outlet obstruction.
- Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion.
- The AIM2 inflammasome is activated in astrocytes during the late phase of EAE.
- The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy.
- The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.
- The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy.
- The NLRP3 Inflammasome Mediates Inflammation Produced by Bladder Outlet Obstruction.
- The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection.
- The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer.
- The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.
- The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.
- The RIP1-RIP3 complex initiates mitochondrial fission to fuel NLRP3.
- The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells).
- The role of interferon-β in the treatment of multiple sclerosis and experimental autoimmune encephalomyelitis - in the perspective of inflammasomes.
- UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis.
- Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation.
- Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo.
- [NLRP3 inflammasome and multiple sclerosis/EAE].