Sequestosome-1 Protein
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Subject Areas on Research
- ATM functions at the peroxisome to induce pexophagy in response to ROS.
- Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity.
- BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.
- Caffeine prevents restenosis and inhibits vascular smooth muscle cell proliferation through the induction of autophagy.
- Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease.
- Dysregulation of mitochondrial bioenergetics and quality control by HIV-1 Tat in cardiomyocytes.
- E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I.
- Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.
- Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation.
- Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy.
- RNA-Seq and ChIP-Seq reveal SQSTM1/p62 as a key mediator of JunB suppression of NF-κB-dependent inflammation.
- Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB.
- Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo.