APOBEC-3G Deaminase
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Subject Areas on Research
- A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor.
- Foamy virus Bet proteins function as novel inhibitors of the APOBEC3 family of innate antiretroviral defense factors.
- Functional domain organization of human APOBEC3G.
- Further investigation of simian immunodeficiency virus Vif function in human cells.
- HIV-1 Vif: counteracting innate antiretroviral defenses.
- Inhibition of a yeast LTR retrotransposon by human APOBEC3 cytidine deaminases.
- Inhibition of alpharetrovirus replication by a range of human APOBEC3 proteins.
- Selective inhibition of Alu retrotransposition by APOBEC3G.
- Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation.
- Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators.
- Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor.
- The betaretrovirus Mason-Pfizer monkey virus selectively excludes simian APOBEC3G from virion particles.
- The intrinsic antiretroviral factor APOBEC3B contains two enzymatically active cytidine deaminase domains.