Liver X Receptors
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Subject Areas on Research
- A Brief Discussion on Lipid Activated Nuclear Receptors and their Potential Role in Regulating Microglia in Age-Related Macular Degeneration (AMD).
- Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice.
- Anthrabenzoxocinones from Streptomyces sp. as liver X receptor ligands and antibacterial agents.
- Cholesterol and breast cancer pathophysiology.
- DIO2 modifies inflammatory responses in chondrocytes.
- Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources.
- Guttiferone I, a new prenylated benzophenone from Garcinia humilis as a liver X receptor ligand.
- Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.
- Identification of a novel set of genes regulated by a unique liver X receptor-alpha -mediated transcription mechanism.
- LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression.
- LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target.
- Liver X receptor is a regulator of orphan nuclear receptor NOR-1 gene transcription in adipocytes.
- Liver X receptors alpha and beta regulate renin expression in vivo.
- Mesenchymal stem cells differentiate into renin-producing juxtaglomerular (JG)-like cells under the control of liver X receptor-alpha.
- Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors.
- Nuclear hormone receptor LXRα inhibits adipocyte differentiation of mesenchymal stem cells with Wnt/beta-catenin signaling.
- Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expression.
- Regulation of ALK-1 signaling by the nuclear receptor LXRbeta.
- Steroidal and triterpenoidal fungal metabolites as ligands of liver X receptors.
- The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X Receptor.
- The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors.