Subject Areas on Research
- Activating mutations in STIM1 and ORAI1 cause overlapping syndromes of tubular myopathy and congenital miosis.
- Inside-out Ca(2+) signalling prompted by STIM1 conformational switch.
- Orai proteins interact with TRPC channels and confer responsiveness to store depletion.
- STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.
- The role of store-operated calcium influx in skeletal muscle signaling.