Transcription Factor HES-1
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Subject Areas on Research
- Dependence of corneal stem/progenitor cells on ocular surface innervation.
- HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development.
- HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly.
- Identification and targeting of a HES1-YAP1-CDKN1C functional interaction in fusion-negative rhabdomyosarcoma.
- Negative regulation of CD4 gene expression by a HES-1-c-Myb complex.
- Notch signaling maintains Leydig progenitor cells in the mouse testis.
- Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study.
- RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.