Patched Receptors
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Subject Areas on Research
- A new Cre driver mouse line, Tcf21/Pod1-Cre, targets metanephric mesenchyme.
- Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2.
- Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway.
- Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis.
- Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors.
- Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation.
- Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis.
- Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma.
- Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.
- Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
- Gorlin syndrome and desmoplastic medulloblastoma: Report of 3 cases with unfavorable clinical course and novel mutations.
- Hedgehog signaling maintains resident hepatic progenitors throughout life.
- Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease.
- Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation.
- Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma.
- Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus.
- Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.
- Patched-one or smoothened gene mutations are infrequent in chondrosarcoma.
- Retrospective family study of childhood medulloblastoma.
- Role for hedgehog pathway in regulating growth and function of invariant NKT cells.
- Sonic hedgehog is required for cardiac outflow tract and neural crest cell development.
- Tissue interactions pattern the mesenchyme of the embryonic mouse lung.
- Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors.