Superoxide Dismutase-1
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Subject Areas on Research
- A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury.
- A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS.
- Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-Mediated Inhibition of Mitochondrial Respiration.
- Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model.
- Design of a Randomized, Placebo-Controlled, Phase 3 Trial of Tofersen Initiated in Clinically Presymptomatic SOD1 Variant Carriers: the ATLAS Study
- Fas(t) balls and Lou Gehrig disease. A clue to selective vulnerability of motor neurons?
- Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis.
- Genomics in the neonatal nursery: Focus on ROP.
- Hydrogen peroxide promotes aging-related platelet hyperactivation and thrombosis.
- Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis.
- Incorporating external information to improve sparse signal detection in rare-variant gene-set-based analyses.
- Intralingual Administration of AAVrh10-miRSOD1 Improves Respiratory But Not Swallowing Function in a Superoxide Dismutase-1 Mouse Model of Amyotrophic Lateral Sclerosis.
- Lack of the P2X7 receptor protects against AMD-like defects and microparticle accumulation in a chronic oxidative stress-induced mouse model of AMD.
- Modification of cysteine 111 in human Cu,Zn-superoxide dismutase.
- Murine muscle stem cell response to perturbations of the neuromuscular junction are attenuated with aging.
- Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
- PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice.
- Regulation of the brain's vascular responses to oxygen.
- Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination.
- Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56δ stabilizes its antiapoptotic activity.
- Superoxide-dependent iron uptake: a new role for anion exchange protein 2.
- The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies.
- Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates.
- Transcription factor-driven alternative localization of Cryptococcus neoformans superoxide dismutase.
- XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells.