RNA Splicing Factors
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Subject Areas on Research
- A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling.
- A negative coregulator for the human ER.
- A novel fibrotic disorder associated with increased dermal fibroblast proliferation and downregulation of genes of the microfibrillar network.
- Acute myeloid leukemia ontogeny is defined by distinct somatic mutations.
- Alternative Splicing of EZH2 pre-mRNA by SF3B3 Contributes to the Tumorigenic Potential of Renal Cancer.
- Deletion of Siah-interacting protein gene in Drosophila causes cardiomyopathy.
- Disrupted gonadogenesis and male-to-female sex reversal in Pod1 knockout mice.
- Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci.
- Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies.
- Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.
- Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients.
- Prognostic Roles of BRAF, KIT, NRAS, IGF2R and SF3B1 Mutations in Mucosal Melanomas.
- RBFOX2 is critical for maintaining alternative polyadenylation patterns and mitochondrial health in rat myoblasts.
- RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure.
- RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure.
- Real-world diagnostic testing patterns for assessment of ring sideroblasts and SF3B1 mutations in patients with newly diagnosed lower-risk myelodysplastic syndromes.
- Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types.
- WTAP Targets the METTL3 m6A-Methyltransferase Complex to Cytoplasmic Hepatitis C Virus RNA to Regulate Infection.