Dishevelled Proteins
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Subject Areas on Research
- Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations.
- Blocking Dishevelled signaling in the noncanonical Wnt pathway in sea urchins disrupts endoderm formation and spiculogenesis, but not secondary mesoderm formation.
- Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2.
- Cytosolic TMEM88 promotes invasion and metastasis in lung cancer cells by binding DVLS.
- Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4.
- Dishevelled-3 activates p65 to upregulate p120-catenin transcription via a p38-dependent pathway in non-small cell lung cancer.
- Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.
- Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.
- IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.
- Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled.
- LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development.
- Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy.
- Signaling by wingless in Drosophila.
- Site-specific casein kinase 1epsilon-dependent phosphorylation of Dishevelled modulates beta-catenin signaling.
- The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal.
- The dishevelled protein is modified by wingless signaling in Drosophila.
- beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins.
- dishevelled and armadillo act in the wingless signalling pathway in Drosophila.
- β-Arrestin and dishevelled coordinate biased signaling.