Homeobox Protein Nkx-2.5
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Subject Areas on Research
- A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5.
- Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.
- Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation.
- Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation.
- Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men.
- Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development.
- Nkx2-5 Second Heart Field Target Gene Ccdc117 Regulates DNA Metabolism and Proliferation.
- RNA-Mediated Reprogramming of Primary Adult Human Dermal Fibroblasts into c-kit(+) Cardiac Progenitor Cells.
- Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function.