Interferon-Induced Helicase, IFIH1

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  Subject Areas on Research

  • Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy. 
  • Engineered Oncolytic Poliovirus PVSRIPO Subverts MDA5-Dependent Innate Immune Responses in Cancer Cells. 
  • Hepatitis C Virus Infection Is Inhibited by a Noncanonical Antiviral Signaling Pathway Targeted by NS3-NS4A. 
  • The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection. 
  • The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections. 
  • Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling.