Myeloid-Derived Suppressor Cells
-
Subject Areas on Research
- A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy.
- AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells.
- Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells.
- Granulocytic MDSC with Deficient CCR5 Alleviates Lipogenesis and Inflammation in Nonalcoholic Fatty Liver Disease.
- Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy.
- Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells.
- Letter by Moris et al Regarding Article, "Cardioprotective Role of Myeloid-Derived Suppressor Cells in Heart Failure".
- Murine CMV induces type 1 IFN that impairs differentiation of MDSCs critical for transplantation tolerance.
- No Evidence That Genetic Variation in the Myeloid-Derived Suppressor Cell Pathway Influences Ovarian Cancer Survival.
- Randomized phase II study of the Bruton tyrosine kinase inhibitor acalabrutinib, alone or with pembrolizumab in patients with advanced pancreatic cancer.
- Receptor tyrosine kinase MerTK suppresses an allogenic type I IFN response to promote transplant tolerance.
- Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation.
- The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling.
- Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells.
- Tumor interferon signaling and suppressive myeloid cells are associated with CAR T-cell failure in large B-cell lymphoma.