THP-1 Cells
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Subject Areas on Research
- A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase.
- An array of 60,000 antibodies for proteome-scale antibody generation and target discovery.
- Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells.
- Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer.
- Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives.
- Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules.
- Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease.
- Diacetyl exposure disrupts iron homeostasis in animals and cells.
- Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy.
- High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity.
- Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.
- IL-23 Enhances C-Fiber-Mediated and Blue Light-Induced Spontaneous Pain in Female Mice.
- IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses.
- Inflammasome signaling in human placental trophoblasts regulates immune defense against Listeria monocytogenes infection.
- Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis.
- Lipid A Has Significance for Optimal Growth of Coxiella burnetii in Macrophage-Like THP-1 Cells and to a Lesser Extent in Axenic Media and Non-phagocytic Cells.
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease.
- Reversal of Epigenetic Silencing Allows Robust HIV-1 Replication in the Absence of Integrase Function.
- Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity.
- The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy.
- The mRNA Cap 2'-O-Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes.