Zinc Finger Protein Gli2
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Subject Areas on Research
- A role for sonic hedgehog signaling in the pathogenesis of human tracheoesophageal fistula.
- Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis.
- Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.
- Evidence for the involvement of the Gli gene family in embryonic mouse lung development.
- Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
- Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis.
- Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors.
- Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease.
- Hedgehog pathway and pediatric nonalcoholic fatty liver disease.
- Hedgehog signaling in human medullary thyroid carcinoma: a novel signaling pathway.
- Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation.
- Increased production of sonic hedgehog by ballooned hepatocytes.
- Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
- Mutations of the Sonic Hedgehog Pathway Underlie Hypothalamic Hamartoma with Gelastic Epilepsy.
- PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms.
- Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes.
- Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage.
- Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1.
- Targeting stem cell behavior in desmoid tumors (aggressive fibromatosis) by inhibiting hedgehog signaling.
- Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling.
- Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes.