-
Subject Areas on Research
-
A mathematical modelling approach to assessing the reliability of biomarkers of glutathione metabolism.
-
A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee.
-
Acetaminophen and hepatic dysfunction in infectious mononucleosis.
-
Acetaminophen and liver disease.
-
Acetaminophen and ondansetron: The central serotonergic connection.
-
Acetaminophen normalizes glucose homeostasis in mouse models for diabetes.
-
Acetaminophen toxicity in cultured trout liver cells. I. Morphological alterations and effects on cytochrome P450 1A1.
-
Acetaminophen toxicity in cultured trout liver cells. II. Maintenance of cytochrome P450 1A1.
-
Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma.
-
Administration of Oral Acetaminophen to Reduce Costs for the Hysterectomy Patient at a Community Hospital.
-
Alternating ibuprofen and acetaminophen in the treatment of febrile children: a pilot study [ISRCTN30487061].
-
Analgesia After Cesarean Delivery in the United States 2008-2018: A Retrospective Cohort Study.
-
Analgesia in the surgical intensive care unit.
-
Analgesic drug use and risk of ovarian cancer.
-
Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium.
-
Assessment and management of donor pain following marrow harvest for allogeneic bone marrow transplantation.
-
Association Between Early Postoperative Acetaminophen Exposure and Acute Kidney Injury in Pediatric Patients Undergoing Cardiac Surgery.
-
Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses.
-
Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.
-
Chronic salicylism resulting in noncardiogenic pulmonary edema requiring hemodialysis.
-
Co-medications that modulate liver injury and repair influence clinical outcome of acetaminophen-associated liver injury.
-
Comedications alter drug-induced liver injury reporting frequency: Data mining in the WHO VigiBase™.
-
Comparative analysis of length of stay, hospitalization costs, opioid use, and discharge status among spine surgery patients with postoperative pain management including intravenous versus oral acetaminophen.
-
Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation.
-
Death of a living liver donor from illicit drugs.
-
Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J.
-
Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.
-
Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction.
-
Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis.
-
Effect of pain management on immunization efficacy in mice.
-
Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice.
-
Effects of Acetaminophen, NSAIDs, Gabapentinoids, and Their Combinations on Postoperative Pulmonary Complications After Total Hip or Knee Arthroplasty.
-
Effects of acetaminophen and nonsteroidal anti-inflammatory drugs on progesterone production by porcine granulosa cells in vitro.
-
Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes.
-
Elevated ghrelin alters the behavioral effects of perinatal acetaminophen exposure in rats.
-
Elevated metabolites of acetaminophen in cord blood of children with obesity.
-
Equal antipyretic effectiveness of oral and rectal acetaminophen: a randomized controlled trial [ISRCTN11886401].
-
Erythromycin vs metoclopramide for facilitating gastric emptying and tolerance to intragastric nutrition in critically ill patients.
-
Evaluating the Implementation of a Preemptive, Multimodal Analgesia Protocol in a Plastic Surgery Office.
-
Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury.
-
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting.
-
Gastric motility function in critically ill patients tolerant vs intolerant to gastric nutrition.
-
Glutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation?
-
Hepatic failure after rectal acetaminophen.
-
Impact of a multimodal analgesic protocol modification on opioid consumption after cesarean delivery: a retrospective cohort study.
-
In vitro effects of acetaminophen and its analogues on human platelet aggregation and thromboxane B2 synthesis.
-
Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity.
-
Inhibition of p53 Sulfoconjugation Prevents Oxidative Hepatotoxicity and Acute Liver Failure.
-
Intravenous Acetaminophen Does Not Decrease Persistent Surgical Pain After Cardiac Surgery.
-
Intravenous acetaminophen analgesia after cardiac surgery: A randomized, blinded, controlled superiority trial.
-
Intravenous acetaminophen: Can the benefit outweigh the cost in selected patients?
-
Kinetic study of paracetamol on prolidase activity in erythrocytes by capillary electrophoresis with Ru(bpy)(3) (2+) electrochemiluminescence detection.
-
Lack of effect of cimetidine on acetaminophen disposition in humans.
-
Letter to the Editor on "Randomized Prospective Trial Comparing the Use of Intravenous Versus Oral Acetaminophen in Total Joint Arthroplasty".
-
Liuweiwuling tablets protect against acetaminophen hepatotoxicity: What is the protective mechanism?
-
Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice.
-
Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase.
-
Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity.
-
Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity.
-
Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice.
-
Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses.
-
Multimodal Pain Management for Major Joint Replacement Surgery.
-
Nitric oxide and acetaminophen-mediated oxidative injury: modulation of interleukin-1-induced nitric oxide synthesis in cultured rat hepatocytes.
-
Nitric oxide decreases oxidant-mediated hepatocyte injury.
-
No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies.
-
Non-parenchymal cell responses in paracetamol (acetaminophen)-induced liver injury.
-
Nonsteroidal anti-inflammatory drugs and acetaminophen in the treatment of an acute muscle injury.
-
Oral Multimodal Analgesia for Total Joint Arthroplasty.
-
Osteopontin expression during early cerebral ischemia-reperfusion in rats: enhanced expression in the right cortex is suppressed by acetaminophen.
-
Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential.
-
Painful acute radiation thyroiditis induced by 131I treatment of Graves' disease.
-
Parental Approach to the Prevention and Management of Fever and Pain Following Childhood Immunizations: A Survey Study.
-
Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity.
-
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
-
Patient preference in a crossover clinical trial of patients with osteoarthritis of the knee or hip: face validity of self-report questionnaire ratings.
-
Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology.
-
Preemptive Oral Acetaminophen for Women Undergoing Total Laparoscopic Hysterectomy.
-
Randomized Population Pharmacokinetic Analysis and Safety of Intravenous Acetaminophen for Acute Postoperative Pain in Neonates and Infants.
-
Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response.
-
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury.
-
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
-
Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice.
-
Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.
-
Safety in Acute Pain Medicine-Pharmacologic Considerations and the Impact of Systems-Based Gaps.
-
Sickle cell vaso-occlusive pain crisis in adults: alternative strategies for management in the emergency department.
-
Skeletal muscle PGF(2)(alpha) and PGE(2) in response to eccentric resistance exercise: influence of ibuprofen acetaminophen.
-
Study of the ability of phenacetin, acetaminophen, and aspirin to induce cytotoxicity, mutation, and morphological transformation in C3H/10T1/2 clone 8 mouse embryo cells.
-
Supratherapeutic dosing of acetaminophen among hospitalized patients.
-
Systematic review: prognostic tests of paracetamol-induced acute liver failure.
-
The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model
-
The effect of antipyretics on immune response and fever following receipt of inactivated influenza vaccine in young children.
-
The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation.
-
The release of DNA into the plasma of mice following hepatic cell death by apoptosis and necrosis.
-
The role of intravenous acetaminophen in multimodal pain protocols for perioperative orthopedic patients.
-
The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism.
-
The role of skeletal muscle in liver glutathione metabolism during acetaminophen overdose.
-
The safety of pediatric use of paracetamol (acetaminophen): a narrative review of direct and indirect evidence.
-
The use of ibuprofen to treat fever in COVID-19: A possible indirect association with worse outcome?
-
The β-adrenoceptor agonist isoproterenol rescues acetaminophen-injured livers through increasing progenitor numbers by Wnt in mice.
-
Therapeutic doses of acetaminophen with co-administration of cysteine and mannitol during early development result in long term behavioral changes in laboratory rats.
-
Underutilization of Acetaminophen in Older Adult Trauma Patients.
-
Use of common analgesic medications and ovarian cancer survival: results from a pooled analysis in the Ovarian Cancer Association Consortium.
-
Utilization of a Preemptive, Multimodal Analgesic Regimen in Adult Ambulatory Septoplasty Patients: A Quality Improvement Project.
-
Warfarin and acetaminophen interaction: a summary of the evidence and biologic plausibility.
-
Keywords of People
-
Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
-
Moorman, Patricia Gripka,
Professor Emeritus in Family Medicine and Community Health,
Duke Cancer Institute
-
Shinohara, Mari L.,
Associate Professor of Immunology,
Cell Biology