Acetyl Coenzyme A

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  Subject Areas on Research

  • A gene controlling variation in Arabidopsis glucosinolate composition is part of the methionine chain elongation pathway. 
  • Acetate metabolism and aging: An emerging connection. 
  • Biochemistry. A glucose-to-gene link. 
  • Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during Exercise. 
  • Chlorpyrifos exposure during neurulation: cholinergic synaptic dysfunction and cellular alterations in brain regions at adolescence and adulthood. 
  • Comprehensive metabolic modeling of multiple 13C-isotopomer data sets to study metabolism in perfused working hearts. 
  • Distribution of reaction intermediates on chicken liver fatty acid synthase. 
  • Elementary steps in the reaction mechanism of chicken liver fatty acid synthase. Acylation of specific binding sites. 
  • Elementary steps in the reaction mechanism of chicken liver fatty acid synthase: acetylation-deacetylation. 
  • Glucose metabolism as a target of histone deacetylase inhibitors. 
  • Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma. 
  • Influence of threonine metabolism on S-adenosylmethionine and histone methylation. 
  • Isolation and characterization of mitochondrial acyl-CoA: glycine N-acyltransferases from kidney. 
  • Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation. 
  • Multiple mass isotopomer tracing of acetyl-CoA metabolism in Langendorff-perfused rat hearts: channeling of acetyl-CoA from pyruvate dehydrogenase to carnitine acetyltransferase. 
  • Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. 
  • Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. 
  • Obesity and lipid stress inhibit carnitine acetyltransferase activity. 
  • Wnt Protein Signaling Reduces Nuclear Acetyl-CoA Levels to Suppress Gene Expression during Osteoblast Differentiation. 
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  Keywords of People

  • McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship