Acidosis

• 

  Subject Areas on Research

  • Acid-base analysis of individuals following two weight loss diets. 
  • Acidic stress promotes a glioma stem cell phenotype. 
  • Acidosis activation of the proton-sensing GPR4 receptor stimulates vascular endothelial cell inflammatory responses revealed by transcriptome analysis. 
  • Acidosis associated with dietotherapy of maple syrup urine disease. 
  • Age-specific associations of reduced estimated glomerular filtration rate with concurrent chronic kidney disease complications. 
  • Antibody to E- and L-selectin does not prevent lung injury or mortality in septic baboons. 
  • Application of high resolution fast atom bombardment and constant B/E ratio linked scanning to the identification and analysis of acylcarnitines in metabolic disease. 
  • Blood lactate: biochemistry, laboratory methods, and clinical interpretation. 
  • Characterization of new diagnostic acylcarnitines in patients with beta-ketothiolase deficiency and glutaric aciduria type I using mass spectrometry. 
  • Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic. 
  • Controlled Multifactorial Coagulopathy: Effects of Dilution, Hypothermia, and Acidosis on Thrombin Generation In Vitro. 
  • Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium. 
  • Dietary acid load: a novel nutritional target in chronic kidney disease? 
  • Disorders of acid-base relationships in the cerebrospinal fluid: a review. 
  • Distinguishing Arterial Ischemic Stroke From Hypoxic-Ischemic Encephalopathy in the Neonate at Birth. 
  • Does the use of diagnostic technology reduce fetal mortality? 
  • Effect of acidosis on glutamine transport by isolated rat renal brush-border and basolateral-membrane vesicles. 
  • Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial. 
  • Effects of Acute, Profound Hypoxia on Healthy Humans: Implications for Safety of Tests Evaluating Pulse Oximetry or Tissue Oximetry Performance. 
  • Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease. 
  • Ethylmalonic aciduria: an organic acidemia with CNS involvement and vasculopathy. 
  • Evaluating a critically ill patient with metabolic acidosis: the ifosfamide paradigm. 
  • Extrarenal Signs of Proximal Renal Tubular Acidosis Persist in Nonacidemic Nbce1b/c-Null Mice. 
  • Glutamine transport into isolated renal membrane vesicles from normal and acidotic rats. 
  • Higher net acid excretion is associated with a lower risk of kidney disease progression in patients with diabetes. 
  • Hypoxic cell death is reduced by pH buffering in a model of engineered heart tissue. 
  • Importance of Metabolic Acidosis as a Health Risk in Chronic Kidney Disease. 
  • Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia. 
  • Influence of acidosis, hypoxemia, and hypotension on neurodevelopmental outcome in very low birth weight infants. 
  • Inhibition of the transcriptional activator protein nuclear factor kappaB prevents hemodynamic instability associated with the whole-body inflammatory response syndrome. 
  • Insulin therapy for ketolactic acidosis complicating malignancy. 
  • Intraretinal pH in diabetic cats. 
  • Ischemic stroke: "acidotoxicity" is a perpetrator. 
  • Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes. 
  • Not so good to the last drop. Ethylene glycol poisoning in a coffee-consuming camper. 
  • Recovery of endothelial function in severe falciparum malaria: relationship with improvement in plasma L-arginine and blood lactate concentrations. 
  • Regulation of cerebral blood flow by arterial PCO2 independent of metabolic acidosis at 5050 m. 
  • Relationship between phosphaluria and acute hypercapnia in the rat. 
  • Role of Acid-Base Homeostasis in Diabetic Kidney Disease. 
  • Serum electrolyte patterns in end-stage renal disease. 
  • Severe multisystem pathology, metabolic acidosis, mitochondrial dysfunction, and early death associated with an X-linked AIFM1 variant. 
  • Severity and Duration of Metabolic Acidosis After Deep Hypothermic Circulatory Arrest for Thoracic Aortic Surgery. 
  • Sodium bicarbonate use and the risk of hypernatremia in thoracic aortic surgical patients with metabolic acidosis following deep hypothermic circulatory arrest. 
  • Targeting Tumor Acidosis and Regulatory T Cells Unmasks Anti-Metastatic Potential of Local Tumor Ablation in Triple-Negative Breast Cancer. 
  • The Treatment of Metabolic Acidosis: An Interactive Case-Based Learning Activity. 
  • The effect of systemic acidosis on perfusion of replanted extremities. 
  • The effect of temperature and pH on the activity of factor VIIa: implications for the efficacy of high-dose factor VIIa in hypothermic and acidotic patients. 
  • The genomic analysis of lactic acidosis and acidosis response in human cancers. 
  • The impact of tumor physiology on camptothecin-based drug development. 
  • The relationship between the tumor physiologic microenvironment and angiogenesis. 
  • The renal excretion of hydrogen ion in renal tubular acidosis. I. quantitative assessment of the response to ammonium chloride as an acid load. 
  • Thresholds of fibrillating leakage currents along intracardiac catheters: an experimental study. 
  • Topiramate-induced confusion following a single ingestion of 400 mg. 
  • Trans-cerebral HCO3- and PCO2 exchange during acute respiratory acidosis and exercise-induced metabolic acidosis in humans. 
  • Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. 
  • pKa does not predict pH potentiation of sodium channel blockade by lidocaine and W6211 in guinea pig ventricular myocardium. 
• 

  Keywords of People

  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Yancy Jr., William Samuel, Professor of Medicine, Medicine, General Internal Medicine