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Subject Areas on Research
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7-Nitrobenz-2-oxa-1,3-diazole (NBD)--phallacidin: synthesis of a fluorescent actin probe.
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8(S)-hydroxyeicosatetraenoic acid is the lipoxygenase metabolite of arachidonic acid that regulates epithelial cell migration in the rat cornea.
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A Mec17-Myosin II Effector Axis Coordinates Microtubule Acetylation and Actin Dynamics to Control Primary Cilium Biogenesis.
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A PAK-like protein kinase is required for maturation of young hyphae and septation in the filamentous ascomycete Ashbya gossypii.
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A Ras1-Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans.
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A biomimetic Schlemm's canal inner wall: A model to study outflow physiology, glaucoma pathology and high-throughput drug screening.
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A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.
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A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics.
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A maturational model for the study of airway smooth muscle adaptation to mechanical oscillation.
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A model for slow axonal transport and its application to neurofilamentous neuropathies.
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A morphogenesis checkpoint monitors the actin cytoskeleton in yeast.
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A new dominant selectable marker for use in Cryptococcus neoformans.
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A new front in cell invasion: The invadopodial membrane.
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A new function for adducin. Calcium/calmodulin-regulated capping of the barbed ends of actin filaments.
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A new method for selection of angular aqueous plexus cells from porcine eyes: a model for Schlemm's canal endothelium.
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A new structural state of myosin.
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A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus.
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A thin-layer model for viscoelastic, stress-relaxation testing of cells using atomic force microscopy: do cell properties reflect metastatic potential?
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A tissue-engineered human trabecular meshwork hydrogel for advanced glaucoma disease modeling.
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A two-tiered mechanism by which Cdc42 controls the localization and activation of an Arp2/3-activating motor complex in yeast.
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ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis.
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ADF/cofilin promotes invadopodial membrane recycling during cell invasion in vivo.
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Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila.
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Abl kinases regulate actin comet tail elongation via an N-WASP-dependent pathway.
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Abl tyrosine kinases modulate cadherin-dependent adhesion upstream and downstream of Rho family GTPases.
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Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.
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Actin Out: Regulation of the Synaptic Cytoskeleton.
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Actin and myosin function in acanthamoeba.
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Actin cytoskeletal disruption following cryopreservation alters the biodistribution of human mesenchymal stromal cells in vivo.
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Actin cytoskeletal network in aging and cancer.
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Actin depolymerization and inhibition of capping induced by pentoxifylline in human lymphocytes and neutrophils.
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Actin dynamics: the arp2/3 complex branches out.
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Actin is required for IFT regulation in Chlamydomonas reinhardtii.
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Actin regulation and surface catalysis.
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Actin-associated neurabin-protein phosphatase-1 complex regulates hippocampal plasticity.
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Actin-dependent myoid elongation in teleost rod inner/outer segments occurs in the absence of net actin polymerization.
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Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation.
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Action potential-coupled Rho GTPase signaling drives presynaptic plasticity.
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Activation of the yeast Arp2/3 complex by Bee1p, a WASP-family protein.
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Active cellular materials.
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Acute local subcutaneous VEGF165 injection for augmentation of skin flap viability: efficacy and mechanism.
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Adaptive F-Actin Polymerization and Localized ATP Production Drive Basement Membrane Invasion in the Absence of MMPs.
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Adducin is an in vivo substrate for protein kinase C: phosphorylation in the MARCKS-related domain inhibits activity in promoting spectrin-actin complexes and occurs in many cells, including dendritic spines of neurons.
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Adducin preferentially recruits spectrin to the fast growing ends of actin filaments in a complex requiring the MARCKS-related domain and a newly defined oligomerization domain.
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Adducin: Ca++-dependent association with sites of cell-cell contact.
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Adducin: a physical model with implications for function in assembly of spectrin-actin complexes.
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Adducin: structure, function and regulation.
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Age-related alterations in actin cytoskeleton and receptor expression in human leukocytes.
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Agonist-stimulated beta-adrenergic receptor internalization requires dynamic cytoskeletal actin turnover.
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Alpha-2 adrenergic receptors stimulate actin organization in developing fetal rat cardiac myocytes.
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Alpha-adducin dissociates from F-actin and spectrin during platelet activation.
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Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy.
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Altered distribution of mitochondria and actin fibers in 3T3 cells cultured on microcarriers.
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Altered genetic response to beta-adrenergic receptor activation in late passage C6 glioma cells.
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Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect.
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Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption.
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Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos.
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Anti-tumor necrosis factor-alpha therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis.
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Apoptosis in atretic ovarian follicles is associated with selective decreases in messenger ribonucleic acid transcripts for gonadotropin receptors and cytochrome P450 aromatase.
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Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain.
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BCL2 interaction with actin in vitro may inhibit cell motility by enhancing actin polymerization.
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Bacterial actin homolog ParM: arguments for an apolar, antiparallel double helix.
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Balancing different types of actin polymerization at distinct sites: roles for Abelson kinase and Enabled.
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Beta-catenin and transforming growth factor beta have distinct roles regulating fibroblast cell motility and the induction of collagen lattice contraction.
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Beyond symmetry-breaking: competition and negative feedback in GTPase regulation.
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Bi-modal regulation of a formin by srGAP2.
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Binding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK.
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Binding of deoxyribonuclease I to actin: a new way to visualize microfilament bundles in nonmuscle cells.
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Biochemical comparison of fast- and slow-contracting squid muscle.
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Biomechanical effects of flow and coculture on human aortic and cord blood-derived endothelial cells.
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Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations.
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Bombesin inhibits alveolarization and promotes pulmonary fibrosis in newborn mice.
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Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization.
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Brain adducin: a protein kinase C substrate that may mediate site-directed assembly at the spectrin-actin junction.
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Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin.
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Brain spectrin. Isolation of subunits and formation of hybrids with erythrocyte spectrin subunits.
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CD34 and α smooth muscle actin distinguish verrucous hyperplasia from verrucous carcinoma.
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CLN5 and CLN8 protein association with ceramide synthase: biochemical and proteomic approaches.
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CNS myelin wrapping is driven by actin disassembly.
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Calcium-dependent regulator protein: localization in mitotic apparatus of eukaryotic cells.
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Carbon monoxide promotes hypoxic pulmonary vascular remodeling.
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Cell Polarity in Yeast.
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Cell biology. Propelling progeny.
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Cell mechanics: dissecting the physical responses of cells to force.
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Cell-cycle checkpoints that ensure coordination between nuclear and cytoplasmic events in Saccharomyces cerevisiae.
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Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes.
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Cellular basis for bimatoprost effects on human conventional outflow.
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Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype.
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Cerebrovascular smooth muscle actin is increased in nondemented subjects with frequent senile plaques at autopsy: implications for the pathogenesis of Alzheimer disease.
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Changes in actin state and chemotactic peptide receptor expression in granulocytes during cytokine administration after autologous bone marrow transplantation.
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Changes in microfilament organization and surface topogrophy upon transformation of chick embryo fibroblasts with Rous sarcoma virus.
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Cigarette smoke-related hydroquinone induces filamentous actin reorganization and heat shock protein 27 phosphorylation through p38 and extracellular signal-regulated kinase 1/2 in retinal pigment epithelium: implications for age-related macular degeneration.
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Clathrin is important for normal actin dynamics and progression of Sla2p-containing patches during endocytosis in yeast.
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Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration.
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Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization.
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Cleavage-furrow formation without F-actin in Chlamydomonas
.
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Clinical studies of hemodialysis access through formaldehyde-fixed arterial allografts.
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Cloned endothelium derived from autoimmune vascular disease retain structural and functional characteristics of normal endothelial cells.
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Co-operativity in protein-protein association. The structure and stability of the actin filament.
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Combined Atomic Force Microscope and Volumetric Light Sheet System for Correlative Force and Fluorescence Mechanobiology Studies.
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Conserved elements of the RAM signaling pathway establish cell polarity in the basidiomycete Cryptococcus neoformans in a divergent fashion from other fungi.
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Contractile proteins in Drosophila development.
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Control of a biomolecular motor-powered nanodevice with an engineered chemical switch.
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Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension.
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Cooperative effect of tumor necrosis factor and gamma-interferon on chemotactic peptide receptor expression and stimulus-induced actin polymerization in HL-60 cells.
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Coordinating cytoskeletal tracks to polarize cellular movements.
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Cordon-bleu is an actin nucleation factor and controls neuronal morphology.
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Cross-talk between TGF-beta1 and IL-6 in human trabecular meshwork cells.
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Cryptococcus neoformans differential gene expression detected in vitro and in vivo with green fluorescent protein.
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Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamics.
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Cyclic mechanical stress and trabecular meshwork cell contractility.
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Cytochalasins induce actin polymerization in human leukocytes.
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Cytoplasmic dynein is required to oppose the force that moves nuclei towards the hyphal tip in the filamentous ascomycete Ashbya gossypii.
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Cytoskeletal actin gates a Cl- channel in neocortical astrocytes.
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Cytoskeletal actin gene families of Xenopus borealis and Xenopus laevis.
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Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cells.
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Cytoskeleton. Evolution in bacteria.
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Dendritic spine geometry can localize GTPase signaling in neurons.
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Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility.
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Developmental mechanism of the periodic membrane skeleton in axons.
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Developmental regulation of calmodulin, actin, and tubulin RNAs during rat testis differentiation.
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Developmental renin expression in mice with a defective renin-angiotensin system.
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Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI.
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Diatom gliding is the result of an actin-myosin motility system.
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Differential Roles of Phospholipase D Proteins in FcεRI-Mediated Signaling and Mast Cell Function.
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Differential effects of cytochalasin B on platelet release, aggregation and contractility: evidence against a contractile mechanism for the release of platelet granular contents.
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Differential gene expression in pubococcygeus muscle from patients with pelvic organ prolapse.
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Differential staining of actin in metaphase spindles with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin and fluorescent DNase: is actin involved in chromosomal movement?
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Differential susceptibility of yeast S and M phase CDK complexes to inhibitory tyrosine phosphorylation.
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Differential uptake of DNA–poly (ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces
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Differentiation- and stress-dependent nuclear cytoplasmic redistribution of myopodin, a novel actin-bundling protein.
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Diffusion of low density lipoprotein-receptor complex on human fibroblasts.
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Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization.
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Directed cell migration on fibronectin gradients: effect of gradient slope.
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Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities.
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Dominant selection system for use in Cryptococcus neoformans.
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Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms.
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Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.
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Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin
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Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis.
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Drosophila spectrin: the membrane skeleton during embryogenesis.
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Drosophilia spectrin. I. Characterization of the purified protein.
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Dual labeling of the fibronectin matrix and actin cytoskeleton with green fluorescent protein variants.
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Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.
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Dynamics of neutrophil membrane compliance and microstructure probed with a micropipet-based piconewton force transducer.
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EF1A1-actin interactions alter mRNA stability to determine differential osteopontin expression in HepG2 and Hep3B cells.
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EJ-Ras inhibits phospholipase C gamma 1 but not actin polymerization induced by platelet-derived growth factor-BB via phosphatidylinositol 3-kinase.
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Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis.
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Effect of interleukin-1β on the expression of actin isoforms in cultured mouse astroglia.
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Effect of streptavidin affinity mutants on the integrin-independent adhesion of biotinylated endothelial cells.
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Effects of cardiotonic steroids on trabecular meshwork cells: search for mediator of ouabain-enhanced outflow facility.
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Effects of chemical inhibition of N-WASP, a critical regulator of actin polymerization on aqueous humor outflow through the conventional pathway.
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Effects of cholesterol-lowering statins on the aqueous humor outflow pathway.
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Effects of growth hormone and IGF-I on cardiac hypertrophy and gene expression in mice.
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Effects of inhibition of mitochondrial protein synthesis in skeletal muscle.
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Effects of novel ethacrynic acid derivatives on human trabecular meshwork cell shape, actin cytoskeletal organization, and transcellular fluid flow.
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Effects of pentoxifylline administration on blood viscosity and leukocyte cytoskeletal function in patients with intermittent claudication.
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Effects of pharmacologic inhibition of protein geranylgeranyltransferase type I on aqueous humor outflow through the trabecular meshwork.
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Effects of taxol and Colcemid on myofibrillogenesis.
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Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin.
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Emergent properties during dorsal closure in Drosophila morphogenesis.
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Ena/VASP proteins regulate activated T-cell trafficking by promoting diapedesis during transendothelial migration.
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Endothelial cell-conditioned medium downregulates smooth muscle contractile protein expression.
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Endothelin-1 induces an increase in total protein synthesis and expression of the smooth muscle alpha-actin gene in vascular smooth muscle cells.
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Enhancing Schwann cell migration using concentration gradients of laminin-derived peptides.
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Erythrocyte membrane tropomyosin. Purification and properties.
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Evidence That an Unconventional Actin Can Provide Essential F-Actin Function and That a Surveillance System Monitors F-Actin Integrity in Chlamydomonas.
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Evidence that myosin does not contribute to force production in chromosome movement.
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Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk.
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Expression of RNAs for calmodulin, actins, and tubulins in rat testis cells.
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Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow.
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Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes.
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Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: paracrine regulation by carcinoma cell-derived members of the transforming growth factor beta family.
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F-actin aggregates in transformed cells.
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F-actin homeostasis through transcriptional regulation and proteasome-mediated proteolysis.
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Feedback control of Swe1p degradation in the yeast morphogenesis checkpoint.
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Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer.
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Filamentous fungal-specific septin AspE is phosphorylated in vivo and interacts with actin, tubulin and other septins in the human pathogen Aspergillus fumigatus.
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Fine-needle aspiration of neural lesions.
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Flow and high affinity binding affect the elastic modulus of the nucleus, cell body and the stress fibers of endothelial cells.
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Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin.
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Fluorescence studies on modes of cytochalasin B and phallotoxin action on cytoplasmic streaming in Chara.
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Focal adhesion integrity is downregulated by the alternatively spliced domain of human tenascin.
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Force fluctuations in three-dimensional suspended fibroblasts.
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Forces drive basement membrane invasion in Caenorhabditis elegans
.
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Formation of myocardial zonal lesions.
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Formin' actin filament bundles.
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Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse.
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Fueling Cell Invasion through Extracellular Matrix.
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Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli.
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Functions of the myosin ATP and actin binding sites are required for C. elegans thick filament assembly.
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Gene expression in the rectus abdominus muscle of patients with and without pelvic organ prolapse.
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Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent.
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Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration.
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Glutamate receptor activation regulates mRNA at both transcriptional and posttranscriptional levels.
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Grab your partner with both hands: cytoskeletal remodeling by Arp2/3 signaling.
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Granulocyte deformability and F-actin content: relationship to diabetes mellitus and retinopathy.
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Growth factor induced activation of Rho and Rac GTPases and actin cytoskeletal reorganization in human lens epithelial cells.
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HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy.
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HDAC6 modulates cell motility by altering the acetylation level of cortactin.
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Hedgehog controls hepatic stellate cell fate by regulating metabolism.
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Hedgehog pathway and pediatric nonalcoholic fatty liver disease.
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Hic-5 Regulates Actin Cytoskeletal Reorganization and Expression of Fibrogenic Markers and Myocilin in Trabecular Meshwork Cells.
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High-affinity augmentation of endothelial cell attachment: long-term effects on focal contact and actin filament formation.
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High-content imaging-based screening of microenvironment-induced changes to stem cells.
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Histochemical analyses of altered fetal lung development following single vs multiple courses of antenatal steroids.
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Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis.
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How vinculin regulates force transmission.
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Human skeletal muscle fibre contractile properties and proteomic profile: adaptations to 3 weeks of unilateral lower limb suspension and active recovery.
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Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein.
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Identification of the spectrin subunit and domains required for formation of spectrin/adducin/actin complexes.
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Identification of virulence mutants of the fungal pathogen Cryptococcus neoformans using signature-tagged mutagenesis.
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Impaired cytoskeletal organization and membrane integrity in lens fibers of a Rho GTPase functional knockout transgenic mouse.
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Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47).
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In vitro modeling of nonhypoxic cold ischemia-reperfusion simulating lung transplantation.
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In vitro proteolysis of brain spectrin by calpain I inhibits association of spectrin with ankyrin-independent membrane binding site(s).
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In vitro reconstitution of cortical actin assembly sites in budding yeast.
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In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast.
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In vivo staining of cytoskeletal actin by autointernalization of nontoxic concentrations of nitrobenzoxadiazole-phallacidin.
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Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6.
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Increased calmodulin affects cell morphology and mRNA levels of cytoskeletal protein genes.
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Induction of angiogenic immediate early genes by activation of FP prostanoid receptors in cultured human ciliary smooth muscle cells.
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Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton.
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Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells.
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Influence of food deprivation on intestinal cholecystokinin and somatostatin.
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Inhibition of poxvirus growth by Terameprocol, a methylated derivative of nordihydroguaiaretic acid.
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Interactions between cellular actin and human respiratory syncytial virus (HRSV).
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Interactions between dystrophin and the sarcolemma membrane.
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Interactions between sustained contractile activity and beta-adrenergic receptors in regulation of gene expression in skeletal muscles.
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Interferon suppresses pinocytosis but stimulates phagocytosis in mouse peritoneal macrophages: related changes in cytoskeletal organization.
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Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-β1 in airway fibroblasts in asthma.
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Intraoperative floppy iris syndrome: report of a case and histopathologic analysis.
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Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles.
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Invading, Leading and Navigating Cells in Caenorhabditis elegans
: Insights into Cell Movement in Vivo
.
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Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene Expression.
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Involvement of a Rac1-Dependent Macropinocytosis Pathway in Plasmid DNA Delivery by Electrotransfection.
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Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis.
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Involvement of gamma and beta actin isoforms in mouse neuroblastoma differentiation.
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Isoforms of alpha-actinin from cardiac, smooth, and skeletal muscle form polar arrays of actin filaments.
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Isolation and characterization of stem cells from the human parathyroid gland.
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JNK signaling coordinates integrin and actin functions during Drosophila embryogenesis.
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Kinase MPK17 and the Peroxisome Division Factor PMD1 Influence Salt-induced Peroxisome Proliferation.
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Kinesin motors as molecular machines.
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L1-dependent neuritogenesis involves ankyrinB that mediates L1-CAM coupling with retrograde actin flow.
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Lack of correlation between induction of chemotactic peptide receptors and stimulus-induced actin polymerization in HL-60 cells treated with dibutyryl cyclic adenosine monophosphate or retinoic acid.
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Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.
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Length oscillation induces force potentiation in infant guinea pig airway smooth muscle.
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Leveraging single protein polymers to measure flexural rigidity.
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Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions.
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Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis.
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Localized glucose import, glycolytic processing, and mitochondria generate a focused ATP burst to power basement-membrane invasion.
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Long-term primary culture of epithelial cells from rainbow trout Oncorhynchus mykiss) liver.
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Longitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphometry in comparison to serum markers.
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Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall.
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Lovastatin-induced cytoskeletal reorganization in lens epithelial cells: role of Rho GTPases.
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Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells.
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MIG-10 (Lamellipodin) stabilizes invading cell adhesion to basement membrane and is a negative transcriptional target of EGL-43 in C. elegans.
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MIG-10 (lamellipodin) has netrin-independent functions and is a FOS-1A transcriptional target during anchor cell invasion in C. elegans.
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MRP4-mediated regulation of intracellular cAMP and cGMP levels in trabecular meshwork cells and homeostasis of intraocular pressure.
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MYH9 E1841K Mutation Augments Proteinuria and Podocyte Injury and Migration.
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Mantle zone lymphoma in a gastric glomus tumor.
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Maspin expression in epithelial ovarian cancer and associations with poor prognosis: a Gynecologic Oncology Group study.
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Mast cell desensitization inhibits calcium flux and aberrantly remodels actin.
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Maximal polar growth potential depends on the polarisome component AgSpa2 in the filamentous fungus Ashbya gossypii.
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Maximal stimulation of meiotic recombination by a yeast transcription factor requires the transcription activation domain and a DNA-binding domain.
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Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells.
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Mechanistic insights into actin-driven polarity site movement in yeast.
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Mesenchymal stem cells differentiate into renin-producing juxtaglomerular (JG)-like cells under the control of liver X receptor-alpha.
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MicroRNA-146a-5p Attenuates Fibrosis-related Molecules in Irradiated and TGF-beta1-Treated Human Hepatic Stellate Cells by Regulating PTPRA-SRC Signaling.
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Microcytic anemia in mk/mk mice is not corrected by retroviral-mediated gene transfer of wild-type p45 NF-E2.
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Microrheology probes length scale dependent rheology.
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Microtubule disruption leads to cellular contraction in human trabecular meshwork cells.
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Mitral valvular interstitial cell responses to substrate stiffness depend on age and anatomic region.
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Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632.
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Modulation of microfilament protein composition by transfected cytoskeletal actin genes.
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Modulation of smooth muscle contractility by CHASM, a novel member of the smoothelin family of proteins.
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Modulation of spectrin-actin assembly by erythrocyte adducin.
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Molecular and phenotypic characterization of a new mouse insertional mutation that causes a defect in the distal vertebrae of the spine.
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Molecular genetic dissection of myosin heavy chain function.
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Molecular mobility on the cell surface.
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Monocyte chemoattractant activity of Ser195-->Ala active site mutant recombinant alpha-thrombin.
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Morphogenesis in the yeast cell cycle: regulation by Cdc28 and cyclins.
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Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition.
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Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy.
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Myocardial injury-induced fibroblast proliferation facilitates retroviral-mediated gene transfer to the rat heart in vivo.
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Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy.
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Myoid differentiation and prognosis in adult pleomorphic sarcomas of the extremity: an analysis of 92 cases.
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Myolipoma of the eyelid.
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Myosin S2 origins track evolution of strong binding on actin by azimuthal rolling of motor domain.
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NLR-1/CASPR Anchors F-Actin to Promote Gap Junction Formation.
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Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10).
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Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation.
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Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton.
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Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.
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Neutrophil elastase induces mucus cell metaplasia in mouse lung.
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Nonequilibrium dynamics of probe filaments in actin-myosin networks.
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Nonequilibrium mechanics of active cytoskeletal networks.
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Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema.
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Novel mitochondrial derived Nuclear Excisosome degrades nuclei during differentiation of prosimian Galago (bush baby) monkey lenses.
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Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork.
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Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains.
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Opposing roles for actin in Cdc42p polarization.
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Overexpression of hMTH in peripheral lymphocytes and risk of prostate cancer: a case-control analysis.
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PRDX6 attenuates oxidative stress- and TGFbeta-induced abnormalities of human trabecular meshwork cells.
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Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis.
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Pancreatic secretory trypsin inhibitor I reduces the severity of chronic pancreatitis in mice overexpressing interleukin-1β in the pancreas.
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Parallel Actin-Independent Recycling Pathways Polarize Cdc42 in Budding Yeast.
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Pentoxifylline modulates deformability, F-actin content, and superoxide anion production of polymorphonuclear leukocytes from diabetic cats.
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Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation.
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Peritubular myoid cells are not the migrating population required for testis cord formation in the XY gonad.
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Phorbol myristate acetate stimulates microtubule and 10-nm filament extension and lysosome redistribution in mouse macrophages.
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Phosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expression.
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Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion.
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Photoreceptor Discs: Built Like Ectosomes.
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Plasma gelsolin and circulating actin correlate with hemodialysis mortality.
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Polymerization of actin. IV. Role of Ca++ and H+ in the assembly of actin and in membrane fusion in the acrosomal reaction of echinoderm sperm.
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Pretranslational regulation of myoglobin gene expression.
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Progesterone receptor activity in leiomyomatosis peritonealis disseminata.
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Prolonged beta-catenin stabilization and tcf-dependent transcriptional activation in hyperplastic cutaneous wounds.
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Protein kinase C beta II specifically binds to and is activated by F-actin.
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Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis.
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Proteins closely related to spectrin and ankyrin are general components of cell membranes.
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Proteomic identification and functional characterization of MYH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity.
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Quantitative analysis of macrophages and perisinusoidal cells in primary biliary cirrhosis.
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Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44.
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Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival.
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Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis.
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Rapid de-localization of actin leading edge components with BDM treatment.
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Rapid deformation of "passive" polymorphonuclear leukocytes: the effects of pentoxifylline.
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Rapid local compression in active gels is caused by nonlinear network response.
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Rapid up-regulation of peptide elongation factor EF-1alpha protein levels is an immediate early event during oxidative stress-induced apoptosis.
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Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans.
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Real-time imaging of morphogenetic movements in Drosophila using Gal4-UAS-driven expression of GFP fused to the actin-binding domain of moesin.
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Red blood cell and fibroblast membranes in Duchenne and myotonic muscular dystrophy.
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Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis.
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Reduced synthesis of pp60src and expression of the transformation-related phenotype in interferon-treated Rous sarcoma virus-transformed rat cells.
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Regulation of G protein-coupled receptor kinase 5 (GRK5) by actin.
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Regulation of cell-cell adhesion by Abi/Diaphanous complexes.
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Regulation of intestinal cholecystokinin and somatostatin mRNA by bombesin in rats.
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Regulation of macrophage motility by Irgm1.
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Regulation of microfilaments and microtubules by calcium and cyclic AMP.
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Regulation of spine structural plasticity by Arc/Arg3.1.
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Regulation of the association of adducin with actin filaments by Rho-associated kinase (Rho-kinase) and myosin phosphatase.
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Regulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders.
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Relationship between 3T3 cell spreading and the strength of adhesion on glass and silane surfaces.
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Resistance to hydrogen peroxide associated with altered catalase mRNA stability in MCF7 breast cancer cells.
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Response of blood leukocytes to thrombin receptor peptides.
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Retinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions.
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Reverse actin sliding triggers strong myosin binding that moves tropomyosin.
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Rho GDP dissociation inhibitor-mediated disruption of Rho GTPase activity impairs lens fiber cell migration, elongation and survival.
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Rho kinase promotes alloimmune responses by regulating the proliferation and structure of T cells.
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RhoB-dependent modulation of postendocytic traffic in polarized Madin-Darby canine kidney cells.
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Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines.
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Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling.
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Role of Scd5, a protein phosphatase-1 targeting protein, in phosphoregulation of Sla1 during endocytosis.
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Role of isoprenylcysteine carboxylmethyltransferase-catalyzed methylation in Rho function and migration.
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Role of lysophospholipid growth factors in the modulation of aqueous humor outflow facility.
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Role of platelet activating factor in the inflammatory and secretory effects of Clostridium difficile toxin A.
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Rvs161p and sphingolipids are required for actin repolarization following salt stress.
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STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib.
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STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo.
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Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro.
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Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
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Scd5p and clathrin function are important for cortical actin organization, endocytosis, and localization of sla2p in yeast.
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Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy.
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Self-organized stress patterns drive state transitions in actin cortices.
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Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p.
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Septin-dependent assembly of a cell cycle-regulatory module in Saccharomyces cerevisiae.
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Sequence divergence of coiled coils--structural rods, myosin filament packing, and the extraordinary conservation of cohesins.
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Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
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Simulated actin reorganization mediated by motor proteins.
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Simultaneous amplification of four DNA repair genes and beta-actin in human lymphocytes by multiplex reverse transcriptase-PCR.
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Singularity in polarization: rewiring yeast cells to make two buds.
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Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet.
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Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis.
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Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes.
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Sphingosine-1-phosphate enhancement of cortical actomyosin organization in cultured human Schlemm's canal endothelial cell monolayers.
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Stepping between membrane microdomains.
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Stimulation of cytoplasmic actin gene transcription and translation in cultured Drosophila cells by ecdysterone.
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Structural changes in isometrically contracting insect flight muscle trapped following a mechanical perturbation.
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Structure and filament dynamics of the pSK41 actin-like ParM protein: implications for plasmid DNA segregation.
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Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes.
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Study of Cryptococcus neoformans actin gene regulation with a beta-galactosidase-actin fusion.
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Study of gastric fluid induced cytokine and chemokine expression in airway smooth muscle cells and airway remodeling.
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Subacute limb ischemia induces skeletal muscle injury in genetically susceptible mice independent of vascular density.
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Superoxide-mediated actin response in post-hypoxic endothelial cells.
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Superresolution microscopy reveals actomyosin dynamics in medioapical arrays.
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Supramolecular and Liquid Crystalline Contributions to the Assembly of Myofibril.
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Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy.
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Survival of retinal pigment epithelium after exposure to prolonged oxidative injury: a detailed gene expression and cellular analysis.
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Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice.
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Symmetry breaking and the establishment of cell polarity in budding yeast.
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Synaptic Actin Dysregulation, a Convergent Mechanism of Mental Disorders?
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T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis.
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Targeted HAS2 Expression Lessens Airway Responsiveness in Chronic Murine Allergic Airway Disease.
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Targeted secretion: Myosin V delivers vesicles through formin condensates.
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Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology.
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Temporal regulation of morphogenetic events in Saccharomyces cerevisiae.
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Temporal spatial expression and function of non-muscle myosin II isoforms IIA and IIB in scar remodeling.
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Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens.
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The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia.
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The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia.
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The Arp2/3 complex has essential roles in vesicle trafficking and transcytosis in the mammalian small intestine.
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The Cell Death Pathway Regulates Synapse Elimination through Cleavage of Gelsolin in Caenorhabditis elegans Neurons.
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The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction.
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The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.
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The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri.
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The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesis.
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The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials.
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The Pseudomonas syringae Type III Effector HopG1 Induces Actin Remodeling to Promote Symptom Development and Susceptibility during Infection.
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The actin gene from Cryptococcus neoformans: structure and phylogenetic analysis.
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The actin membrane skeleton in Drosophila development.
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The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation.
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The conundrum of cryptogenic cirrhosis: Adverse outcomes without treatment options.
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The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure.
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The discovery of the prokaryotic cytoskeleton: 25th anniversary.
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The effect of halothane on cultured fibroblasts and neuroblastoma cells.
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The effect of irrigation solution at different temperatures on articular cartilage metabolism.
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The effects of heparin cofactor II-derived chemotaxins on neutrophil actin conformation and cyclic AMP levels.
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The identification of a second actin-binding region in spinophilin/neurabin II.
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The junctional complex of the membrane skeleton.
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The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo.
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The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits.
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The requirement of reversible cysteine sulfenic acid formation for T cell activation and function.
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The role of F-actin and myosin in epithelial cell rheology.
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The role of Smad3 in mediating mouse hepatic stellate cell activation.
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The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle.
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The role of calcium-independent phospholipase A2γ in modulation of aqueous humor drainage and Ca2+ sensitization of trabecular meshwork contraction.
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The role of protein kinase C in modulation of aqueous humor outflow facility.
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The role of the cytoskeleton in aging.
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The role of the lens actin cytoskeleton in fiber cell elongation and differentiation.
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The spectrin-actin junction of erythrocyte membrane skeletons.
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The tail domain of the Aspergillus fumigatus class V myosin MyoE orchestrates septal localization and hyphal growth.
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The transcription factor HLH-2/E/Daughterless regulates anchor cell invasion across basement membrane in C. elegans.
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The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42.
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Therapeutic targets in focal and segmental glomerulosclerosis.
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Tissue interactions pattern the mesenchyme of the embryonic mouse lung.
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Toxin injury-dependent switched expression between EF-1 alpha and its sister, S1, in rat skeletal muscle.
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Tracking shallow chemical gradients by actin-driven wandering of the polarization site.
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Transcription inhibits the replication of autonomously replicating plasmids in human cells.
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Transdifferentiation of human endothelial progenitors into smooth muscle cells.
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Transgelin-2: Biochemical and Clinical Implications in Cancer and Asthma.
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Triple negative breast cancer: outcome correlation with immunohistochemical detection of basal markers.
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Tropomyosin: a new component of the erythrocyte membrane skeleton.
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Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis via Matrix Metallopeptidase 13-Mediated Matrix Degradation.
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Two CDC42 paralogues modulate Cryptococcus neoformans thermotolerance and morphogenesis under host physiological conditions.
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Two Rac paralogs regulate polarized growth in the human fungal pathogen Cryptococcus neoformans.
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UNC-6 (netrin) orients the invasive membrane of the anchor cell in C. elegans.
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UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity
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Ultrastructural abnormalities in CA1 hippocampus caused by deletion of the actin regulator WAVE-1.
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Ultrastructural changes associated with dexamethasone-induced ocular hypertension in mice.
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Unified biophysical mechanism for cell-shape oscillations and cell ingression.
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Universally Conserved Relationships between Nuclear Shape and Cytoplasmic Mechanical Properties in Human Stem Cells.
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Unphosphorylated gelsolin is localized in regions of cell-substratum contact or attachment in Rous sarcoma virus-transformed rat cells.
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Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast.
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Variable presentation of nemaline myopathy: novel mutation of alpha actin gene.
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Vascular smooth muscle actin is reduced in Alzheimer disease brain: a quantitative analysis.
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Viral sequences enable efficient and tissue-specific expression of transgenes in Xenopus.
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Wound healing: The power of the purse string.
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X-ray diffraction evidence for myosin-troponin connections and tropomyosin movement during stretch activation of insect flight muscle.
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YAP/TAZ Mediate TGFβ2-Induced Schlemm's Canal Cell Dysfunction.
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alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells.
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beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation.
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c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF.
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crinkled reveals a new role for Wingless signaling in Drosophila denticle formation.
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sCD44 overexpression increases intraocular pressure and aqueous outflow resistance.
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zipper Nonmuscle myosin-II functions downstream of PS2 integrin in Drosophila myogenesis and is necessary for myofibril formation.
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β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability.
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Keywords of People
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Bennett, Vann,
George Barth Geller Distinguished Professor of Molecular Biology,
Duke Cancer Institute
-
Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
-
Choi, Steven Sok,
Associate Professor of Medicine,
Medicine, Gastroenterology
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Erickson, Harold Paul,
Professor Emeritus of Cell Biology,
Cell Biology
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Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
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Soderling, Scott Haydn,
George Barth Geller Distinguished Professor of Molecular Biology,
Cell Biology
-
Stinnett, Sandra Sue,
Associate Professor of Biostatistics & Bioinformatics,
Biostatistics & Bioinformatics
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Sunday, Mary Elizabeth Anne,
Professor of Pathology,
Cell Biology
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Taylor, Gregory Alan,
Professor in Medicine,
Immunology