Acyl Coenzyme A
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Subject Areas on Research
- A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation.
- A Prob(e)able Route to Lysine Acylation.
- Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver.
- Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase.
- Association of Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Autoantibodies With DRB1*07:01 and Severe Myositis in Juvenile Myositis Patients.
- Biomedical applications of high-performance liquid chromatography-mass spectrometry with continuous-flow fast atom bombardment.
- Brain Arachidonic Acid Incorporation and Turnover are not Altered in the Flinders Sensitive Line Rat Model of Human Depression.
- Catabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet.
- Catabolism of 4-hydroxyacids and 4-hydroxynonenal via 4-hydroxy-4-phosphoacyl-CoAs.
- Characterization of the reaction mechanism for the XL-I form of bovine liver xenobiotic/medium-chain fatty acid:CoA ligase.
- Chronic ethanol treatment induces H2O2 production selectively in pericentral regions of the liver lobule.
- Combined high-performance liquid chromatographic-continuous-flow fast atom bombardment mass spectrometric analysis of acylcoenzyme A compounds.
- Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism.
- Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion.
- Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus).
- Elementary steps in the reaction mechanism of chicken liver fatty acid synthase: beta-ketoacyl reductase and enoyl reductase.
- Enzymology of long-chain base synthesis by liver: characterization of serine palmitoyltransferase in rat liver microsomes.
- Expression of recombinant human methylmalonyl-CoA mutase: in primary mut fibroblasts and Saccharomyces cerevisiae.
- Fluorescent properties of pyrene bound at specific acylation sites of chicken liver fatty acid synthase.
- Formation of a free acyl adenylate during the activation of 2-propylpentanoic acid. Valproyl-AMP: a novel cellular metabolite of valproic acid.
- Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance.
- High-Resolution Metabolomics with Acyl-CoA Profiling Reveals Widespread Remodeling in Response to Diet.
- Identification of S-nitroso-CoA reductases that regulate protein S-nitrosylation.
- Identification of csypyrone B1 as the novel product of Aspergillus oryzae type III polyketide synthase CsyB.
- Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle.
- Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism.
- L-carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia.
- Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
- Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.
- Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis.
- Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy.
- Non-enzymatically derived minor lipids found in Escherichia coli lipid extracts.
- Novel approach in LC-MS/MS using MRM to generate a full profile of acyl-CoAs: discovery of acyl-dephospho-CoAs.
- Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine.
- Reactive Acyl-CoA Species Modify Proteins and Induce Carbon Stress.
- Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner.
- Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression.
- Stereochemistry of the reactions catalyzed by chicken liver fatty acid synthase.
- Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors.
- Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model.