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Subject Areas on Research
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A colony color method identifies the vulnerability of mitochondria to oxidative damage.
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A simplified prognostic index for chronic lymphocytic leukemia treated with ibrutinib: Results from a multicenter retrospective cohort study.
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A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes.
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Acceptability of pre-exposure prophylaxis among men who have sex with men and transgender women in Northern Thailand.
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Accuracy of Self-Report and Pill-Count Measures of Adherence in the FEM-PrEP Clinical Trial: Implications for Future HIV-Prevention Trials.
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Activity of Galidesivir in a Hamster Model of SARS-CoV-2.
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Activity of psoralen-functionalized nanoscintillators against cancer cells upon X-ray excitation.
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Acute renal failure after initiation of tenofovir disoproxil fumarate.
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Add-on adefovir is superior to a switch to entecavir as rescue therapy for Lamivudine-resistant chronic hepatitis B.
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Adefovir dipivoxil in chronic hepatitis B: history and current uses.
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Adenine and adenosine are toxic to human lymphoblast mutants defective in purine salvage enzymes.
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Adverse event burden in older patients with CLL receiving bendamustine plus rituximab or ibrutinib regimens: Alliance A041202.
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An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral.
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Analysis of the mouse transcriptome for genes involved in the function of the nervous system.
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Antiretroviral medications: adverse effects on the kidney.
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Antiretroviral preexposure prophylaxis for HIV prevention.
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Atomic structures of excited state A-T Hoogsteen base pairs in duplex DNA by combining NMR relaxation dispersion, mutagenesis, and chemical shift calculations.
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Base modifications in plasmid DNA caused by potassium permanganate.
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Base stacking and molecular polarizability: effect of a methyl group in the 5-position of pyrimidines.
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C-C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products.
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CLL-517 Hypertension as an Adverse Event of Ibrutinib: Does Age Matter?
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Changes in glomerular kidney function among HIV-1-uninfected men and women receiving emtricitabine-tenofovir disoproxil fumarate preexposure prophylaxis: a randomized clinical trial.
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Changes in proteinuria and albuminuria with initiation of antiretroviral therapy: data from a randomized trial comparing tenofovir disoproxil fumarate/emtricitabine versus abacavir/lamivudine.
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Characterization of low-grade arthralgia, myalgia, and musculoskeletal pain with ibrutinib therapy: pooled analysis of clinical trials in patients with chronic lymphocytic leukemia and mantle cell lymphoma.
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Chronic Kidney Disease and Antiretroviral Therapy in HIV-Positive Individuals: Recent Developments.
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Comparative efficacy of nucleoside/nucleotide reverse transcriptase inhibitors in combination with efavirenz: results of a systematic overview.
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Complete Response of a Young Woman With MYD88WT Bing-Neel Syndrome on Ibrutinib Monotherapy Following a Single Cycle of B Hyper-CVAD/IT MTX.
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Concerning the mechanism of FSH action: rapid stimulation of testicular synthesis of nuclear RNA.
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Coordinate regulation of the proximal and distal steps of the pathway of purine synthesis de nono in WI-L2 human lymphoblasts.
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Copper ion-mediated modification of bases in DNA in vitro by benzoyl peroxide.
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Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG).
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Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
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Cytotoxic and metabolic effects of adenosine and adenine on human lymphoblasts.
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Design of tenofovir-UC781 combination microbicide vaginal gels.
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Determinants of Photolyase's DNA Repair Mechanism in Mesophiles and Extremophiles.
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Differential specificities and simultaneous occupancy of human MutSalpha nucleotide binding sites.
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Distinct MutS DNA-binding modes that are differentially modulated by ATP binding and hydrolysis.
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Drivers of treatment patterns in patients with chronic lymphocytic leukemia stopping ibrutinib or idelalisib therapies.
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Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD.
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EcoRI methylase. Physical and catalytic properties of the homogeneous enzyme.
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Economic evaluation of ART in resource-limited countries.
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Effects of high levels of DNA adenine methylation on methyl-directed mismatch repair in Escherichia coli.
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Effects of sofosbuvir-based hepatitis C treatment on the pharmacokinetics of tenofovir in HIV/HCV-coinfected individuals receiving tenofovir disoproxil fumarate.
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Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection.
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Efficacy of bendamustine and rituximab in unfit patients with previously untreated chronic lymphocytic leukemia. Indirect comparison with ibrutinib in a real-world setting. A GIMEMA-ERIC and US study.
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Efficient sporulation of yeast in media buffered near pH6.
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Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs.
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Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction.
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Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine.
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Extended storage of AS-1 and AS-3 leukoreduced red blood cells for 15 days after deglycerolization and resuspension in AS-3 using an automated closed system.
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Extent of equilibrium perturbation of the DNA helix upon enzymatic methylation of adenine residues.
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FEM-PrEP: adherence patterns and factors associated with adherence to a daily oral study product for pre-exposure prophylaxis.
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Fanconi syndrome accompanied by renal function decline with tenofovir disoproxil fumarate: a prospective, case-control study of predictors and resolution in HIV-infected patients.
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Final analysis of a phase 1/2b study of ibrutinib combined with carfilzomib/dexamethasone in patients with relapsed/refractory multiple myeloma.
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Flipping of the ribosomal A-site adenines provides a basis for tRNA selection.
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Gout and the regulation of purine biosynthesis.
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HIV preexposure prophylaxis in the United States: impact on lifetime infection risk, clinical outcomes, and cost-effectiveness.
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Hepatitis B virus viral load and treatment decision.
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Hypoxanthine uptake in isolated rat renal cortical tubule fragments.
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Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL.
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Ibrutinib in combination with rituximab in relapsed or refractory mantle cell lymphoma: a single-centre, open-label, phase 2 trial.
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Ibrutinib plus fludarabine, cyclophosphamide, and rituximab as initial treatment for younger patients with chronic lymphocytic leukaemia: a single-arm, multicentre, phase 2 trial.
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Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia.
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Ibrutinib-associated invasive fungal diseases in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: An observational study.
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Ibrutinib: a new targeted therapy for hematologic cancers.
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In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction.
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Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy.
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Insight into the CSA tensors of nucleobase carbons in RNA polynucleotides from solution measurements of residual CSA: towards new long-range orientational constraints.
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Insights into Watson-Crick/Hoogsteen breathing dynamics and damage repair from the solution structure and dynamic ensemble of DNA duplexes containing m1A.
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Kidney disease in patients with HIV infection and AIDS.
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Kinetic studies of hydrogen bonding. 1-Cyclohexyluracil and 9-ethyladenine.
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Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial.
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Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited settings.
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Management of patients coinfected with HCV and HIV: a close look at the role for direct-acting antivirals.
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Measurable residual disease does not preclude prolonged progression-free survival in CLL treated with ibrutinib.
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Methyl-directed DNA mismatch repair in Escherichia coli.
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Mitigation of autophagy ameliorates hepatocellular damage following ischemia-reperfusion injury in murine steatotic liver.
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Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration.
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Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.
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Molecular and genetic biomarkers implemented from next-generation sequencing provide treatment insights in clinical practice for Waldenström macroglobulinemia.
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Multicompartmental pharmacokinetic model of tenofovir delivery by a vaginal gel.
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Newer treatments for HIV in children.
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Optimal sequencing of ibrutinib, idelalisib, and venetoclax in chronic lymphocytic leukemia: results from a multicenter study of 683 patients.
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Outcomes of front-line ibrutinib treated CLL patients excluded from landmark clinical trial.
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Perception of HIV risk and adherence to a daily, investigational pill for HIV prevention in FEM-PrEP.
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Phase 1 trial of ibrutinib and carfilzomib combination therapy for relapsed or relapsed and refractory multiple myeloma.
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Phase 1 trial of rituximab, lenalidomide, and ibrutinib in previously untreated follicular lymphoma: Alliance A051103.
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Phase 2 study of the safety and efficacy of umbralisib in patients with CLL who are intolerant to BTK or PI3Kδ inhibitor therapy.
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Phase II study of amonafide in advanced pancreatic adenocarcinoma.
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Phase III open-label randomized study of cytarabine in combination with amonafide L-malate or daunorubicin as induction therapy for patients with secondary acute myeloid leukemia.
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Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS.
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Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria.
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Potential kidney toxicity from the antiviral drug tenofovir: new indications, new formulations, and a new prodrug.
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Pre-exposure prophylaxis works--it's time to deliver.
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Preexposure prophylaxis for HIV infection among African women.
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Probing Watson-Crick and Hoogsteen base pairing in duplex DNA using dynamic nuclear polarization solid-state NMR spectroscopy.
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Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal.
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Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism.
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Purine reutilization and synthesis de novo in APRT deficient long-term lymphocyte lines.
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Purine reutilization and synthesis de novo in long-term human lymphocyte cell lines deficient in adenine phosphoribosyltransferase activity.
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Purine toxicity in human lymphoblasts.
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Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn I endonuclease.
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Rejuvenation solution as an adjunct cold storage solution maintains physiological haemoglobin oxygen affinity during early-storage period of red blood cells.
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Removal of N-6-methyladenine by the nucleotide excision repair pathway triggers the repair of mismatches in yeast gap-repair intermediates.
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Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib.
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Robust IR-based detection of stable and fractionally populated G-C+ and A-T Hoogsteen base pairs in duplex DNA.
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Role of transmethylation reactions in cellular motility and phagocytosis.
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Salmonella typhimurium SA host specificity system is based on deoxyribonucleic acid-adenine methylation.
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Short communication: Inadequate vitamin D exacerbates parathyroid hormone elevations in tenofovir users.
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Simplified maintenance therapy with abacavir/lamivudine/zidovudine plus tenofovir after sustained HIV load suppression: four years of follow-up.
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Site-specific methylases induce the SOS DNA repair response in Escherichia coli.
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Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
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Structured treatment interruptions with tenofovir monotherapy for simian immunodeficiency virus-infected newborn macaques.
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Targeting the B-cell receptor pathway: a review of current and future therapies for non-Hodgkin's lymphoma.
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Targeting the IL-2 inducible kinase in melanoma; a phase 2 study of ibrutinib in systemic treatment-refractory distant metastatic cutaneous melanoma: preclinical rationale, biology, and clinical activity (NCI9922).
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Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.
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Telbivudine protects renal function in patients with chronic hepatitis B infection in conjunction with adefovir-based combination therapy.
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Tenofovir alafenamide for HIV infection: is less more?
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Tenofovir has inferior efficacy in adefovir-experienced chronic hepatitis B patients compared to nucleos(t)ide-naïve patients.
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The C-terminal domain of the adenine-DNA glycosylase MutY confers specificity for 8-oxoguanine.adenine mispairs and may have evolved from MutT, an 8-oxo-dGTPase.
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The conserved dinucleotide AG of the 3' splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors.
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The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.
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The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years.
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The science of being a study participant: FEM-PrEP participants' explanations for overreporting adherence to the study pills and for the whereabouts of unused pills.
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Toxicities and outcomes of 616 ibrutinib-treated patients in the United States: a real-world analysis.
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Transmethylation reactions are required for initial morphologic and biochemical responses of human monocytes to chemoattractants.
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Ublituximab plus ibrutinib versus ibrutinib alone for patients with relapsed or refractory high-risk chronic lymphocytic leukaemia (GENUINE): a phase 3, multicentre, open-label, randomised trial.
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Unraveling the structural complexity in a single-stranded RNA tail: implications for efficient ligand binding in the prequeuosine riboswitch.
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Urine processing impacts uric acid level in HIV-infected adults: implications for diagnosing tenofovir-associated proximal tubulopathy.
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Urolithiasis under atazanavir boosted and tenofovir therapy: a case report.
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Vaginal deployment and tenofovir delivery by microbicide gels.
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Will a new tenofovir prodrug for the treatment of HIV reduce the risk of nephrotoxicity?
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m6A and YTHDF proteins contribute to the localization of select neuronal mRNAs.
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m6A-mediated translation regulation.