Adenine
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Subject Areas on Research
- 8-Hydroxyadenine as the intermediate in the oxidation of adenine to 2, 8-dihydroxyadenine by xanthine oxidase.
- A colony color method identifies the vulnerability of mitochondria to oxidative damage.
- A strong effect of AT mutational bias on amino acid usage in Buchnera is mitigated at high-expression genes.
- Accuracy of Self-Report and Pill-Count Measures of Adherence in the FEM-PrEP Clinical Trial: Implications for Future HIV-Prevention Trials.
- Activity of psoralen-functionalized nanoscintillators against cancer cells upon X-ray excitation.
- Acute renal failure after initiation of tenofovir disoproxil fumarate.
- Adenine and adenosine are toxic to human lymphoblast mutants defective in purine salvage enzymes.
- Adenine auxotrophic mutants of Aspergillus oryzae: development of a novel transformation system with triple auxotrophic hosts.
- Analysis of the mouse transcriptome for genes involved in the function of the nervous system.
- Antiretroviral medications: adverse effects on the kidney.
- Antiretroviral preexposure prophylaxis for HIV prevention.
- Atomic structures of excited state A-T Hoogsteen base pairs in duplex DNA by combining NMR relaxation dispersion, mutagenesis, and chemical shift calculations.
- Base stacking and molecular polarizability: effect of a methyl group in the 5-position of pyrimidines.
- C-C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products.
- Changes in glomerular kidney function among HIV-1-uninfected men and women receiving emtricitabine-tenofovir disoproxil fumarate preexposure prophylaxis: a randomized clinical trial.
- Changes in proteinuria and albuminuria with initiation of antiretroviral therapy: data from a randomized trial comparing tenofovir disoproxil fumarate/emtricitabine versus abacavir/lamivudine.
- Chronic Kidney Disease and Antiretroviral Therapy in HIV-Positive Individuals: Recent Developments.
- Comparative efficacy of nucleoside/nucleotide reverse transcriptase inhibitors in combination with efavirenz: results of a systematic overview.
- Concerning the mechanism of FSH action: rapid stimulation of testicular synthesis of nuclear RNA.
- Coordinate regulation of the proximal and distal steps of the pathway of purine synthesis de nono in WI-L2 human lymphoblasts.
- Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG).
- Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
- Cytotoxic and metabolic effects of adenosine and adenine on human lymphoblasts.
- Design of tenofovir-UC781 combination microbicide vaginal gels.
- Determinants of Photolyase's DNA Repair Mechanism in Mesophiles and Extremophiles.
- Development of a novel quadruple auxotrophic host transformation system by argB gene disruption using adeA gene and exploiting adenine auxotrophy in Aspergillus oryzae.
- Differential specificities and simultaneous occupancy of human MutSalpha nucleotide binding sites.
- Distinct MutS DNA-binding modes that are differentially modulated by ATP binding and hydrolysis.
- Dynamical treatment of charge transfer through duplex nucleic acids containing modified adenines.
- Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD.
- EcoRI methylase. Physical and catalytic properties of the homogeneous enzyme.
- Effects of high levels of DNA adenine methylation on methyl-directed mismatch repair in Escherichia coli.
- Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection.
- Efficient sporulation of yeast in media buffered near pH6.
- Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs.
- Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction.
- Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine.
- Extended storage of AS-1 and AS-3 leukoreduced red blood cells for 15 days after deglycerolization and resuspension in AS-3 using an automated closed system.
- Extent of equilibrium perturbation of the DNA helix upon enzymatic methylation of adenine residues.
- FEM-PrEP: adherence patterns and factors associated with adherence to a daily oral study product for pre-exposure prophylaxis.
- Fanconi syndrome accompanied by renal function decline with tenofovir disoproxil fumarate: a prospective, case-control study of predictors and resolution in HIV-infected patients.
- Flipping of the ribosomal A-site adenines provides a basis for tRNA selection.
- Gout and the regulation of purine biosynthesis.
- Hepatitis B virus viral load and treatment decision.
- Hypoxanthine uptake in isolated rat renal cortical tubule fragments.
- In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction.
- Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy.
- Insight into the CSA tensors of nucleobase carbons in RNA polynucleotides from solution measurements of residual CSA: towards new long-range orientational constraints.
- Insights into Watson-Crick/Hoogsteen breathing dynamics and damage repair from the solution structure and dynamic ensemble of DNA duplexes containing m1A.
- Kidney disease in patients with HIV infection and AIDS.
- Kinetic studies of hydrogen bonding. 1-Cyclohexyluracil and 9-ethyladenine.
- Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited settings.
- Management of patients coinfected with HCV and HIV: a close look at the role for direct-acting antivirals.
- Methyl-directed DNA mismatch repair in Escherichia coli.
- Mitigation of autophagy ameliorates hepatocellular damage following ischemia-reperfusion injury in murine steatotic liver.
- Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration.
- Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.
- Multicompartmental pharmacokinetic model of tenofovir delivery by a vaginal gel.
- Newer treatments for HIV in children.
- Perception of HIV risk and adherence to a daily, investigational pill for HIV prevention in FEM-PrEP.
- Pharmacokinetics of antiretroviral regimens containing tenofovir disoproxil fumarate and atazanavir-ritonavir in adolescents and young adults with human immunodeficiency virus infection.
- Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS.
- Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria.
- Potential kidney toxicity from the antiviral drug tenofovir: new indications, new formulations, and a new prodrug.
- Preexposure prophylaxis for HIV infection among African women.
- Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal.
- Purine reutilization and synthesis de novo in APRT deficient long-term lymphocyte lines.
- Purine reutilization and synthesis de novo in long-term human lymphocyte cell lines deficient in adenine phosphoribosyltransferase activity.
- Purine toxicity in human lymphoblasts.
- Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn I endonuclease.
- Removal of N-6-methyladenine by the nucleotide excision repair pathway triggers the repair of mismatches in yeast gap-repair intermediates.
- Robust IR-based detection of stable and fractionally populated G-C+ and A-T Hoogsteen base pairs in duplex DNA.
- Role of transmethylation reactions in cellular motility and phagocytosis.
- Salmonella typhimurium SA host specificity system is based on deoxyribonucleic acid-adenine methylation.
- Short communication: Inadequate vitamin D exacerbates parathyroid hormone elevations in tenofovir users.
- Simplified maintenance therapy with abacavir/lamivudine/zidovudine plus tenofovir after sustained HIV load suppression: four years of follow-up.
- Site-specific methylases induce the SOS DNA repair response in Escherichia coli.
- Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190.
- Structured treatment interruptions with tenofovir monotherapy for simian immunodeficiency virus-infected newborn macaques.
- Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.
- Tenofovir alafenamide for HIV infection: is less more?
- The C-terminal domain of the adenine-DNA glycosylase MutY confers specificity for 8-oxoguanine.adenine mispairs and may have evolved from MutT, an 8-oxo-dGTPase.
- The conserved dinucleotide AG of the 3' splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors.
- The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.
- The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years.
- The science of being a study participant: FEM-PrEP participants' explanations for overreporting adherence to the study pills and for the whereabouts of unused pills.
- Transmethylation reactions are required for initial morphologic and biochemical responses of human monocytes to chemoattractants.
- Unraveling the structural complexity in a single-stranded RNA tail: implications for efficient ligand binding in the prequeuosine riboswitch.
- Urine processing impacts uric acid level in HIV-infected adults: implications for diagnosing tenofovir-associated proximal tubulopathy.
- Vaginal deployment and tenofovir delivery by microbicide gels.
- Will a new tenofovir prodrug for the treatment of HIV reduce the risk of nephrotoxicity?