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Subject Areas on Research
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5' UTR m(6)A Promotes Cap-Independent Translation.
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A KINETIC INVESTIGATION OF THE INTERACTION OF ADENOSINE-5'-TRIPHOSPHATE WITH DIVALENT METAL IONS.
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A conserved bulged adenosine in a peripheral duplex of the antigenomic HDV self-cleaving RNA reduceskinetic trapping of inactive conformations.
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A critical reappraisal of aspirin for secondary prevention in patients with ischemic heart disease.
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A mathematical model of glutathione metabolism.
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A potentially abundant junctional RNA motif stabilized by m6A and Mg2.
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A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions.
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A randomized controlled trial of allopurinol vs. placebo added on to antipsychotics in patients with schizophrenia or schizoaffective disorder.
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A randomized trial to compare the safety of rivaroxaban vs aspirin in addition to either clopidogrel or ticagrelor in acute coronary syndrome: The design of the GEMINI-ACS-1 phase II study.
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AZD6140.
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Acadesine inhibits neutrophil CD11b up-regulation in vitro and during in vivo cardiopulmonary bypass.
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Activity of Galidesivir in a Hamster Model of SARS-CoV-2.
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Acute termination of supraventricular tachycardia by adenosine during pregnancy.
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Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.
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Adenine and adenosine are toxic to human lymphoblast mutants defective in purine salvage enzymes.
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Adenosine A(3)-receptor stimulation attenuates postischemic dysfunction through K(ATP) channels.
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Adenosine as a non-opioid analgesic in the perioperative setting.
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Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction: results of a multicenter, randomized, placebo-controlled trial: the Acute Myocardial Infarction STudy of ADenosine (AMISTAD) trial.
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Adenosine for myocardial protection in acute myocardial infarction.
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Adenosine for temporary flow arrest during intracranial aneurysm surgery: a single-center retrospective review.
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Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials.
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Adenosine stress cardiac magnetic resonance imaging.
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Adenosine triphosphate activates ion permeabilities in biliary epithelial cells.
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Adenosine-induced flow arrest to facilitate intracranial aneurysm clip ligation does not worsen neurologic outcome.
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Adenosine-induced flow arrest to facilitate intracranial aneurysm clip ligation: dose-response data and safety profile.
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Adenosine-induced modulation of excitatory amino acid transport across isolated brain arterioles.
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Adenosine-induced transient asystole for intracranial aneurysm surgery: a retrospective review.
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Advances in antiplatelet therapy: agents in clinical development.
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Aedes albopictus cells resistant to adenosine because of a defect in nucleoside transport.
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Alkaline Phosphatase, Soluble Extracellular Adenine Nucleotides, and Adenosine Production after Infant Cardiopulmonary Bypass.
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Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection.
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An additional class of m6
A readers.
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An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral.
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Analysis of myocardial function in orthotopic cardiac allografts after prolonged storage in UW solution.
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Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches.
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Antiangiogenic agents protect liver sinusoidal lining cells from cold preservation injury in rat liver transplantation.
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Antiplatelet and anticoagulation agents in acute coronary syndromes: what is the current status and what does the future hold?
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Antiplatelet therapy beyond 2012: role of personalized medicine.
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Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis.
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Aspirin and clopidogrel resistance: consideration and management.
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Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor.
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Balancing the risk of spontaneous ischemic and major bleeding events in acute coronary syndromes.
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Baseline Q waves as a prognostic modulator in patients with ST-segment elevation: insights from the PLATO trial.
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Basis for resistance to 3-deazaaristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase, in human B-lymphoblasts.
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Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial.
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Bone targeting nanocarrier-assisted delivery of adenosine to combat osteoporotic bone loss.
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Bronchospasm after intravenous adenosine administration.
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Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling.
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Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared with clopidogrel: Data from the PLATO Trial.
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Cardiovascular magnetic resonance accurately detects obstructive coronary artery disease in suspected non-ST elevation myocardial infarction: a sub-analysis of the CARMENTA Trial.
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Changes in diastolic cardiac function in developing and stable perinephritic hypertension in conscious dogs.
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Characterization of cardiac A1 adenosine receptors by ligand binding and photoaffinity labeling.
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Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes.
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Clinical validation of AggreGuide A-100 ADP, a novel assay for assessing the antiplatelet effect of oral P2Y12 antagonists.
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Clinically significant bleeding with low-dose rivaroxaban versus aspirin, in addition to P2Y12 inhibition, in acute coronary syndromes (GEMINI-ACS-1): a double-blind, multicentre, randomised trial.
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Cloning of the gene encoding Leishmania donovani S-adenosylhomocysteine hydrolase, a potential target for antiparasitic chemotherapy.
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Clopidogrel (Plavix) and cardiac surgical patients: implications for platelet function monitoring and postoperative bleeding.
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Combined immunodeficiency disease associated with adenosine deaminase deficiency. Report on a workshop held in Albany, New York, October 1, 1973.
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Common actions of adenosine receptor agonists in modulating human trabecular meshwork cell transport.
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Comparison of postoperative pain outcomes after vertical or Pfannenstiel incision for major gynecologic surgery.
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Comparison of the prognostic value of regadenoson and adenosine myocardial perfusion imaging.
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Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study.
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Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) trial.
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Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons.
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Conversation in cardiology: Is there a need for clinical trials for the nonhyperemic pressure ratios?
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Coronary Microvascular Dysfunction as a Mechanism of Angina in Severe AS: Prospective Adenosine-Stress CMR Study.
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Correlation of adenosine echocardiography and thallium scintigraphy.
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Correlation of intrinsic optical signal, cerebral blood flow, and evoked potentials during activation of rat somatosensory cortex.
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Covalent labelling of ligand binding sites of human placental S-adenosylhomocysteine hydrolase with 8-azido derivatives of adenosine and cyclic AMP.
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Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
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Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
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Current controversies in the use of aspirin and ticagrelor for the treatment of thrombotic events.
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Cystatin C and estimated glomerular filtration rate as predictors for adverse outcome in patients with ST-elevation and non-ST-elevation acute coronary syndromes: results from the Platelet Inhibition and Patient Outcomes study.
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Cytotoxic and metabolic effects of adenosine and adenine on human lymphoblasts.
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DART-seq: an antibody-free method for global m6A detection.
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Design and rationale for the Effects of Ticagrelor and Clopidogrel in Patients with Peripheral Artery Disease (EUCLID) trial.
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Dexmedetomidine: therapeutic use for the termination of reentrant supraventricular tachycardia.
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Direct Conversion of Human Pluripotent Stem Cells to Osteoblasts With a Small Molecule.
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Direct RNA sequencing reveals m6A modifications on adenovirus RNA are necessary for efficient splicing.
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Direct evidence for (G)O6···H2-N4(C)+ hydrogen bonding in transient G(syn)-C+ and G(syn)-m5C+ Hoogsteen base pairs in duplex DNA from cytosine amino nitrogen off-resonance R1ρ relaxation dispersion measurements.
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Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss.
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ENTPD1 (CD39) Expression Inhibits UVR-Induced DNA Damage Repair through Purinergic Signaling and Is Associated with Metastasis in Human Cutaneous Squamous Cell Carcinoma.
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Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses.
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Economic analysis of ticagrelor therapy from a U.S. perspective: results from the PLATO study.
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Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial.
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Effect of adenosine-regulating agent acadesine on morbidity and mortality associated with coronary artery bypass grafting: the RED-CABG randomized controlled trial.
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Effect of alpha-isopropylmalate on the synthesis of RNA and protein in Neurospora.
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Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.
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Effects of dose ranging of adenosine infusion on electrocardiographic findings during and after general anesthesia.
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Effects of leukocyte depleted blood on renal reperfusion injury in a porcine model.
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Efficiency comparison between 99m Tc-tetrofosmin and 99m Tc-sestamibi myocardial perfusion studies.
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Electrocardiographic infarct size assessment after thrombolysis: insights from the Acute Myocardial Infarction STudy ADenosine (AMISTAD) trial.
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Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism.
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Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation.
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Enhanced cardiac preservation with oxygenated University of Wisconsin solution.
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Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing.
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Evaluation of ischemic heart disease.
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Evaluation of solutions for small intestinal preservation. Biochemical changes as a function of storage time.
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Examining biology and pharmacology-based hypotheses in the PLATO trial.
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Experience with combined hepatic, pancreaticoduodenal, and renal procurement with UW solution.
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Explaining the unexpected: insights from the PLATelet inhibition and clinical Outcomes (PLATO) trial comparing ticagrelor and clopidogrel. Editorial on Serebruany "Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified" (Thromb Haemost 2011; 105.5).
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Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression.
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Factors contributing to the lower mortality with ticagrelor compared with clopidogrel in patients undergoing coronary artery bypass surgery.
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First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.
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Flipping the script: viral capitalization of RNA modifications.
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Group I intron self-splicing with adenosine: evidence for a single nucleoside-binding site.
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HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia.
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Heterologous desensitization of the inhibitory A1 adenosine receptor-adenylate cyclase system in rat adipocytes. Regulation of both Ns and Ni.
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High-dose, but not low-dose, aspirin impairs anticontractile effect of ticagrelor following ADP stimulation in rat tail artery smooth muscle cells.
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High-threshold Ca2+ currents in rat hippocampal interneurones and their selective inhibition by activation of GABA(B) receptors.
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Hormone-sensitive adenylate cyclase. Delineation of a trypsin-sensitive site in the pathway of receptor-mediated inhibition.
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How RNA modifications regulate the antiviral response.
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How country-specific should a country-specific cost-effectiveness analysis be?
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Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis.
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Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase.
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Identification of N6
-methyladenosine reader proteins.
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Immune-related intestinal chloride secretion. II. Effect of adenosine on T84 cell line.
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Impact of donor factors and preservation on function and survival after liver transplantation.
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Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial.
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Impact of morphine on antiplatelet effects of oral P2Y12 receptor inhibitors.
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In Vivo Sequestration of Innate Small Molecules to Promote Bone Healing.
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In-hospital switching between adenosine diphosphate receptor inhibitors in patients with acute myocardial infarction treated with percutaneous coronary intervention: Insights into contemporary practice from the TRANSLATE-ACS study.
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Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study.
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Incremental prognostic value of RNA ejection fraction measurements during pharmacologic stress testing: a comparison with clinical and perfusion variables.
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Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment.
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Infant cardiopulmonary bypass: CD73 kinetics, association with clinical outcomes, and influence on serum adenosine production capacity.
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Influence of Zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed.
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Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease.
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Inhibition of adenosine-1 receptor-mediated preglomerular vasoconstriction in AT1A receptor-deficient mice.
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Inhibition of tumor necrosis factor release from cultured rat Kupffer cells by agents that reduce graft failure from storage injury.
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Inhibitory effects of ticagrelor compared with clopidogrel on platelet function in patients with acute coronary syndromes: the PLATO (PLATelet inhibition and patient Outcomes) PLATELET substudy.
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Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms.
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Intestinal transplantation: the University of Wisconsin experience.
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Intravenous adenosine selectively increases blood flow to xenotransplanted intracerebral gliomas.
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Letter by Grbel et al regarding article, "administration of a loading dose has no additive effect on platelet aggregation during the switch from ongoing clopidogrel treatment to ticagrelor in patients with acute coronary syndrome".
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Letter by Moris et al Regarding Article, "Ticagrelor in Acute Stroke or Transient Ischemic Attack in Asian Patients: From the SOCRATES Trial (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes)".
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Lifetime cost-effectiveness analysis of ticagrelor in patients with acute coronary syndromes based on the PLATO trial: a Singapore healthcare perspective.
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Limits in the detection of m6A changes using MeRIP/m6A-seq.
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Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction.
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MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization.
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Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-Low Induction of Therapy Resistance.
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Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow.
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Meta-analysis of direct and indirect comparison of ticagrelor and prasugrel effects on platelet reactivity.
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Methylthioadenosine Suppresses Salmonella Virulence.
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Microgel-Assisted Delivery of Adenosine to Accelerate Fracture Healing.
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Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling.
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Molecular form of adenosine deaminase in severe combined immunodeficiency.
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More Evidence for Non-P2Y12-Mediated Effects of Ticagrelor.
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Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release.
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Myocardial uptake and clearance of T1-201 in healthy subjects: comparison of adenosine-induced hyperemia and exercise stress.
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N(6)-Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding.
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N6-Methyladenosine Regulates Host Responses to Viral Infection.
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N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.
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N6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein.
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N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.
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N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle.
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N6-phenyladenosines: pronounced effect of phenyl substituents on affinity for A2 adenosine receptors.
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NMR Chemical Exchange Measurements Reveal That N6-Methyladenosine Slows RNA Annealing.
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New insights into adenosine-receptor-mediated immunosuppression and the role of adenosine in causing the immunodeficiency associated with adenosine deaminase deficiency.
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Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities.
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Optimizing platelet P2Y12 inhibition for patients undergoing PCI.
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Outcome and causes of renal deterioration evaluated by serial cystatin C measurements in acute coronary syndrome patients -- results from the PLATelet inhibition and patient Outcomes (PLATO) study.
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Outcome prediction in patients at high risk for coronary artery disease: comparison between 99mTc tetrofosmin and 99mTc sestamibi.
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Outcomes of Patients with Critical Limb Ischaemia in the EUCLID Trial.
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P2Y12 Receptor Blockade and Myocardial Perfusion.
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Paroxysmal high-grade atrioventricular block and syncope in a previously healthy child: what is the mechanism?
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Perioperative cardiac complications and 30-day mortality in patients undergoing intracranial aneurysmal surgery with adenosine-induced flow arrest: a retrospective comparative study.
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Perturbations in S-adenosylhomocysteine and S-adenosylmethionine metabolism: effects on transmethylation.
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Pharmacodynamic evaluation of switching from ticagrelor to prasugrel in patients with stable coronary artery disease: Results of the SWAP-2 Study (Switching Anti Platelet-2).
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Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the ONSET-OFFSET and RESPOND studies.
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Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.
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Phase 2, double-blind, placebo-controlled, dose-response trial of intravenous adenosine for perioperative analgesia.
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Phase Ia/b, Open-Label, Multicenter Study of AZD4635 (an Adenosine A2A Receptor Antagonist) as Monotherapy or Combined with Durvalumab, in Patients with Solid Tumors.
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Phenotypic dissections of the Blastocladiella emersonii zoospore's developmental choice.
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Phorbol esters enhance neurotransmitter-stimulated cyclic AMP production in rat brain slices.
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Platelet reactivity during ticagrelor maintenance therapy: a patient-level data meta-analysis.
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Platelet-related biomarkers and their response to inhibition with aspirin and p2y12-receptor antagonists in patients with acute coronary syndrome.
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Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine.
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Poststress measurements of left ventricular function with gated perfusion SPECT: comparison with resting measurements by using a same-day perfusion-function protocol.
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Prior smoking status, clinical outcomes, and the comparison of ticagrelor with clopidogrel in acute coronary syndromes-insights from the PLATelet inhibition and patient Outcomes (PLATO) trial.
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Procurement, preservation, and transport of cadaver kidneys.
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Prognostic value of normal exercise and adenosine (99m)Tc-tetrofosmin SPECT imaging: results from the multicenter registry of 4,728 patients.
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Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer.
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Pseudouridine and N6-methyladenosine modifications weaken PUF protein/RNA interactions.
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Pulmonary edema post-cardioversion: a potential calcium signalling problem.
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Pulmonary function in patients with acute coronary syndrome treated with ticagrelor or clopidogrel (from the Platelet Inhibition and Patient Outcomes [PLATO] pulmonary function substudy).
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Purine nucleotides contribute to pulmonary vasodilation caused by birth-related stimuli in the ovine fetus.
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Purine synthesis and excretion in mutants of the WI-L2 human lymphoblastoid line deficient in adenosine kinase (AK) and adenine phosphoribosyltransferase (APRT).
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Purine toxicity in human lymphoblasts.
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Quantitative ST-depression in acute coronary syndromes: the PLATO electrocardiographic substudy.
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RNA N6-Methyladenosine and the Regulation of RNA Localization and Function in the Brain.
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RNA modification of an RNA modifier prevents self-RNA sensing.
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RNA modifications go viral.
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Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.
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Rationale and design of the Affordability and Real-world Antiplatelet Treatment Effectiveness after Myocardial Infarction Study (ARTEMIS): A multicenter, cluster-randomized trial of P2Y12 receptor inhibitor copayment reduction after myocardial infarction.
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Rationale and design of the safe and timely antithrombotic removal - ticagrelor (STAR-T) trial: A prospective, multi-center, double-blind, randomized controlled trial evaluating reductions in postoperative bleeding with intraoperative removal of ticagrelor by the drugsorb™-ATR device in patients undergoing cardiothoracic surgery within 48 hours from last ticagrelor dose.
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Re-design of Rhodobacter sphaeroides dimethyl sulfoxide reductase. Enhancement of adenosine N1-oxide reductase activity.
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Regulation of Co-transcriptional Pre-mRNA Splicing by m6
A through the Low-Complexity Protein hnRNPG.
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Regulation of Viral Infection by the RNA Modification N6-Methyladenosine.
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Regulation of glutamate and aspartate release from slices of the hippocampal CA1 area: effects of adenosine and baclofen.
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Regulation of glutamate and aspartate release from the Schaffer collaterals and other projections of CA3 hippocampal pyramidal cells.
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Requirements for T lymphocyte migration in explanted lymph nodes.
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Response to letter regarding article, "Ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials".
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Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study.
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Rethinking m6A Readers, Writers, and Erasers.
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Review of the accumulated PLATO documentation supports reliable and consistent superiority of ticagrelor over clopidogrel in patients with acute coronary syndrome: Commentary on: DiNicolantonio JJ, Tomek A, Inactivations, deletions, non-adjudications, and downgrades of clinical endpoints on ticagrelor: serious concerns over the reliability of the PLATO trial, International Journal of Cardiology, 2013.
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Role of transmethylation reactions in cellular motility and phagocytosis.
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S-Adenosylhomocysteine hydrolase from human placenta. Affinity purification and characterization.
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S-Adenosylhomocysteine metabolism in adenosine deaminase deficient cells.
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S-adenosylhomocysteine catabolism and basis for acquired resistance during treatment of T-cell acute lymphoblastic leukemia with 2'-deoxycoformycin alone and in combination with 9-beta-D-arabinofuranosyladenine.
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S-adenosylhomocysteine hydrolase is an adenosine-binding protein: a target for adenosine toxicity.
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S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin.
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ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial: insights from the ECG substudy.
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Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia.
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Safety and efficacy of ticagrelor and clopidogrel in primary percutaneous coronary intervention.
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Signaling via P2Y12 may be critical for early stabilization of platelet aggregates.
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Small molecule-driven direct conversion of human pluripotent stem cells into functional osteoblasts.
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Specific photoaffinity labelling of inhibitory adenosine receptors.
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Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors.
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Stimulus-specific effects of pentoxifylline on neutrophil CR3 expression, degranulation, and superoxide production.
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Structural mapping of rabbit muscle phosphofructokinase. Distance between the adenosine cyclic 3',5'-phosphate binding site and a reactive sulfhydryl group.
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Structure of the N-terminal domain of GRP94. Basis for ligand specificity and regulation.
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Structures of human ENT1 in complex with adenosine reuptake inhibitors.
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Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: evidence for A2 receptors on rat Kupffer cells.
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Switching of adenosine diphosphate receptor inhibitor after hospital discharge among myocardial infarction patients: Insights from the Treatment with Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) observational study.
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TP53 genomic status regulates sensitivity of gastric cancer cells to the histone methylation inhibitor 3-deazaneplanocin A (DZNep).
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Targeting purinergic pathway to enhance radiotherapy-induced immunogenic cancer cell death.
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Termination of paroxysmal supraventricular tachycardia by tecadenoson (CVT-510), a novel A1-adenosine receptor agonist.
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Thallium-201 myocardial imaging in patients with coronary artery disease: comparison of intravenous adenosine and oral dipyridamole.
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The Dogged Search for Cryptic Effects of Ticagrelor: Wishful Thinking or Real Benefits Beyond P2Y12 Inhibition?
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The GS Protein-coupled A2a Adenosine Receptor Controls T Cell Help in the Germinal Center.
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The PARTHENON Clinical Development Program: the Role of Ticagrelor in Patients with Atherothrombotic Disease.
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The PLATO trial reveals further opportunities to improve outcomes in patients with acute coronary syndrome. Editorial on Serebruany. "Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified" (Thromb Haemost 2011; 105.5).
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The birth of the Epitranscriptome: deciphering the function of RNA modifications.
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The coronary pressure-flow determinants left ventricular compliance in dogs.
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The dynamic epitranscriptome: N6-methyladenosine and gene expression control.
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The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies.
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The efficacy of ticagrelor is maintained in women with acute coronary syndromes participating in the prospective, randomized, PLATelet inhibition and patient Outcomes (PLATO) trial.
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The m6A reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis.
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The power of more than one.
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The predictive value of donor liver biopsies on the development of primary nonfunction after orthotopic liver transplantation.
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The rat testicular A1 adenosine receptor-adenylate cyclase system.
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The use of UW solution in clinical transplantation. A 4-year experience.
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The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities.
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The use of tomographic myocardial perfusion scanning to evaluate an electrocardiographic salvage estimation method in patients with acute myocardial infarction: an AMISTAD substudy. Acute Myocardial Infarction Study Adenosine.
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Ticagrelor Compared With Clopidogrel in Patients With Prior Lower Extremity Revascularization for Peripheral Artery Disease.
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Ticagrelor Following Coronary Artery Bypass Grafting: For Better Vein Graft Patency or Better Patient Outcomes?
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Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial.
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Ticagrelor effects on myocardial infarction and the impact of event adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) trial.
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Ticagrelor for the treatment of arterial thrombosis.
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Ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials.
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Ticagrelor versus Clopidogrel in Peripheral Artery Disease.
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Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease.
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Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: a substudy from the prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial.
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Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis.
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Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack.
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Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial.
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Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: results from the PLATO (Platelet Inhibition and Patient Outcomes) trial.
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Ticagrelor versus clopidogrel in patients with acute coronary syndromes.
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Ticagrelor versus genotype-driven antiplatelet therapy for secondary prevention after acute coronary syndrome: a cost-effectiveness analysis.
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Ticagrelor with aspirin or alone in high-risk patients after coronary intervention: Rationale and design of the TWILIGHT study.
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Trabodenoson, an Adenosine Mimetic With A1 Receptor Selectivity Lowers Intraocular Pressure by Increasing Conventional Outflow Facility in Mice.
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Transient adenosine-induced asystole during the surgical treatment of anterior circulation cerebral aneurysms: technical note.
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Transmethylation reactions are required for initial morphologic and biochemical responses of human monocytes to chemoattractants.
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Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages.
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Understanding the Adverse Effects of Ticagrelor in Practice.
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Unexpected Cardiac MRI Findings in Patients Presenting to the Emergency Department for Possible Acute Coronary Syndrome.
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Unravelling the smokers' paradox: cigarette smoking, high-risk coronary artery disease and enhanced clinical efficacy of oral P2Y₁₂ inhibitors.
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Update on preservation of liver grafts.
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Use of multiple radioligands to characterize adenosine receptors in human placenta.
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Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies.
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Utilization of pediatric donors for pancreas transplantation.
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Value of cardiovascular magnetic resonance stress perfusion testing for the detection of coronary artery disease in women.
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Vasoactive drugs produce selective changes in flow to experimental brain tumors.
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Viral Epitranscriptomics.
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m(1)A and m(1)G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs.
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m6A minimally impacts the structure, dynamics, and Rev ARM binding properties of HIV-1 RRE stem IIB.
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pH-Sensitive nanocarrier assisted delivery of adenosine to treat osteoporotic bone loss.
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scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells.
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