Calcium-Transporting ATPases
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Subject Areas on Research
- A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene.
- Activation of MYD116 (gadd34) expression following transient forebrain ischemia of rat: implications for a role of disturbances of endoplasmic reticulum calcium homeostasis.
- Activation of four enzymes by two series of calmodulin mutants with point mutations in individual Ca2+ binding sites.
- Alterations in calcium metabolism in murine macrophages by the benzene metabolite 1,4-benzoquinone.
- Association between human erythrocyte calmodulin and the cytoplasmic surface of human erythrocyte membranes.
- Bepridil and cetiedil. Vasodilators which inhibit Ca2+-dependent calmodulin interactions with erythrocyte membranes.
- Binding stoichiometry and structural mapping of the epsilon polypeptide of chloroplast coupling factor 1.
- Biochemical and cytochemical comparison of surface membranes from normal and dystrophic chickens.
- Ca(2+)-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells.
- Changes in endoplasmic reticulum Ca(2-)-ATPase mRNA levels in transient cerebral ischemia of rat: a quantitative polymerase chain reaction study.
- Chloroplast coupling factor 1: dependence of rotational correlation time on polypeptide composition.
- Depletion of neuronal endoplasmic reticulum calcium stores by thapsigargin: effect on protein synthesis.
- Eca1, a sarcoplasmic/endoplasmic reticulum Ca2+-ATPase, is involved in stress tolerance and virulence in Cryptococcus neoformans.
- Effect of nitric oxide on endoplasmic reticulum calcium homeostasis, protein synthesis and energy metabolism.
- Effect of temperature on bradykinin-induced arachidonate release and calcium mobilization in vascular endothelial cells.
- Effects of interleukin-1 on calcium signaling and the increase of filamentous actin in isolated and in situ articular chondrocytes.
- Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein.
- Fast-twitch and slow-twitch/cardiac Ca2+ ATPase genes map to human chromosomes 16 and 12.
- Gene delivery approaches to heart failure treatment.
- Increased Ca2+ -ATPase activity associated with methylation of phospholipids in human erythrocytes.
- Inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase differentially regulates contractile function in cardiac myocytes from normotensive and spontaneously hypertensive rats: role of Ca2+ regulatory proteins.
- Intracellular mediators of insulin action.
- Mechanism of calcium influx in endothelial cells: role of intracellular calcium.
- Myocardial myoglobin deficiency in various animal models of congestive heart failure.
- Myosin from human erythrocytes.
- Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation.
- Reconstitution of a T cell receptor-stimulated plasma membrane calcium transporter: lack of dependence on inositol phosphates.
- Recovery of neuronal protein synthesis after irreversible inhibition of the endoplasmic reticulum calcium pump.
- Red blood cell and fibroblast membranes in Duchenne and myotonic muscular dystrophy.
- Regulation of extracellular calcium entry in endothelial cells: role of intracellular calcium pool.
- Relation of neuronal endoplasmic reticulum calcium homeostasis to ribosomal aggregation and protein synthesis: implications for stress-induced suppression of protein synthesis.
- Response of neurons to an irreversible inhibition of endoplasmic reticulum Ca(2+)-ATPase: relationship between global protein synthesis and expression and translation of individual genes.
- Response of the hypertrophied left ventricle to tachycardia: importance of maturation.
- Role of calcium in the activation of erp72 and heme oxygenase-1 expression on depletion of endoplasmic reticulum calcium stores in rat neuronal cell culture.
- Sarcoplasmic reticulum Ca-release channel and ATP-synthesis activities are early myocardial markers of heart failure produced by rapid ventricular pacing in dogs.
- Spermine. A regulator of mitochondrial calcium cycling.
- Targeted overexpression of phospholamban to mouse atrium depresses Ca2+ transport and contractility.
- Thapsigargin stimulates Ca2+ entry in vascular smooth muscle cells: nicardipine-sensitive and -insensitive pathways.
- The Aspergillus fumigatus P-type Golgi apparatus Ca2+/Mn2+ ATPase PmrA is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis.
- The skeletal muscle calcium release channel: coupled O2 sensor and NO signaling functions.
- Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation.
- Transient cerebral ischemia activates processing of xbp1 messenger RNA indicative of endoplasmic reticulum stress.
- Unifying concept for the coupling between ion pumping and ATP hydrolysis or synthesis.
- accordion, a zebrafish behavioral mutant, has a muscle relaxation defect due to a mutation in the ATPase Ca2+ pump SERCA1.
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Keywords of People
- Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
- Juvvadi, Praveen Rao, Associate Professor in Pediatrics, Pediatrics, Infectious Diseases
- Steinbach, William J., Samuel L. Katz Distinguished Professor of Pediatrics, Duke Innovation & Entrepreneurship