Adenoviruses, Human

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  Subject Areas on Research

  • A comparison of viral fitness and virulence between emergent adenovirus 14p1 and prototype adenovirus 14p strains. 
  • A compensatory base change in U1 snRNA suppresses a 5' splice site mutation. 
  • A modified rapid method of nucleic acid isolation from suspension of matured virus: applied in restriction analysis of DNA from an adenovirus prototype strain and a patient isolate. 
  • A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing. 
  • A replication-defective human adenovirus recombinant serves as a highly efficacious vaccine carrier. 
  • Adenovirus infection of differentiated F9 cells results in a global shut-off of differentiation-induced gene expression. 
  • Adenovirus transmission--worthy of our attention. 
  • Adenovirus type 3 outbreak in connecticut associated with a novel variant. 
  • Adult adenovirus infections: loss of orphaned vaccines precipitates military respiratory disease epidemics. For the Adenovirus Surveillance Group. 
  • Alternative poly(A) site utilization during adenovirus infection coincides with a decrease in the activity of a poly(A) site processing factor. 
  • Beyond Oncolytics: E1B55K-Deleted Adenovirus as a Vaccine Delivery Vector. 
  • Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. 
  • Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. 
  • DNA octamer element can confer E1A trans-activation, and adenovirus infection results in a stimulation of the DNA-binding activity of OTF-1/NFIII factor. 
  • Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenoviruses. 
  • Distinct DNA targets for trans-activation by HTLV-1 tax and adenovirus E1A. 
  • E1A-dependent trans-activation of the c-fos promoter requires the TATAA sequence. 
  • Effect of HIV-1 envelope cytoplasmic tail on adenovirus primed virus encoded virus-like particle immunizations. 
  • Effect of mutant IkappaB on cytokine-induced activation of NF-kappaB in cultured human RPE cells. 
  • Emergent US adenovirus 3 strains associated with an epidemic and serious disease. 
  • Emergent strain of human adenovirus endemic in Iowa. 
  • Epidemiology of human adenovirus and molecular characterization of human adenovirus 55 in China, 2009-2012. 
  • Experimental and numerical studies of adenovirus delivery to outflow tissues of perfused human anterior segments. 
  • Expression analysis of the matrix GLA protein and VE-cadherin gene promoters in the outflow pathway. 
  • Expression of aquaporin-1 in human trabecular meshwork cells: role in resting cell volume. 
  • Gene therapy of cystic fibrosis lung disease using E1 deleted adenoviruses: a phase I trial. 
  • Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints. 
  • Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors. 
  • Human adenovirus 14a: a new epidemic threat. 
  • Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo. 
  • Immunology of gene therapy with adenoviral vectors in mouse skeletal muscle. 
  • Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis. 
  • Induction of a cellular enzyme for energy metabolism by transforming domains of adenovirus E1a. 
  • Large epidemic of respiratory illness due to adenovirus types 7 and 3 in healthy young adults. 
  • Molecular analysis of adenovirus isolates from vaccinated and unvaccinated young adults. 
  • Molecular epidemiology of adenovirus type 7 in the United States, 1966-2000. 
  • Molecular typing of clinical adenovirus specimens by an algorithm which permits detection of adenovirus coinfections and intermediate adenovirus strains. 
  • Outbreak of febrile respiratory illness associated with human adenovirus type 14p1 in Gansu Province, China. 
  • PCR analysis of egyptian respiratory adenovirus isolates, including identification of species, serotypes, and coinfections. 
  • Persistently adenovirus-infected lymphoid cells express microRNAs derived from the viral VAI and especially VAII RNA. 
  • Phosphorylation-dependent activation of the adenovirus-inducible E2F transcription factor in a cell-free system. 
  • Receptor class desensitization of leukocyte chemoattractant receptors. 
  • Recombinant adenovirus vector expressing wild-type p53 is a potent inhibitor of prostate cancer cell proliferation. 
  • Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac251) challenge. 
  • Replication-attenuated Human Adenoviral Type 4 vectors elicit capsid dependent enhanced innate immune responses that are partially dependent upon interactions with the complement system. 
  • Simplified microneutralization test for serotyping adenovirus isolates. 
  • Six-year retrospective surveillance of gastroenteritis viruses identified at ten electron microscopy centers in the United States and Canada. 
  • Sp1 transcription factor is required for in vitro basal and Tat-activated transcription from the human immunodeficiency virus type 1 long terminal repeat. 
  • Structure-based high-throughput epitope analysis of hexon proteins in B and C species human adenoviruses (HAdVs). 
  • Studies of viral antibody responses among Amish families. 
  • Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues. 
  • Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo. 
  • VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases. 
  • Vaccine-preventable adenoviral respiratory illness in US military recruits, 1999-2004. 
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  Keywords of People

  • Liton, Paloma Borrajo, Associate Professor in Ophthalmology, Pathology
  • Yang, Yiping, Professor of Medicine, Immunology