Administration, Inhalation
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Subject Areas on Research
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"Low-level" carbon monoxide administration may carry risk.
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A Computational Study of Nasal Spray Deposition Pattern in Four Ethnic Groups.
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A Systematic Review of Patient- and Family-Level Inhaled Corticosteroid Adherence Interventions in Black/African Americans.
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A novel inhaled organic nitrate that affects pulmonary vascular tone in a piglet model of hypoxia-induced pulmonary hypertension.
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A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS.
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A programmable smoke delivery device for PET imaging with cigarettes containing 11C-nicotine.
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A randomized trial of nicotine replacement therapy in combination with reduced-nicotine cigarettes for smoking cessation.
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A review of the use of adjunctive therapies in severe acute asthma exacerbation in critically ill children.
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A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.
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Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal Staphylococcus aureus sepsis.
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Acute effects of inhaled nitric oxide on pulmonary and cardiac function in preterm infants with evolving bronchopulmonary dysplasia.
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Acute renal failure in cystic fibrosis: association with inhaled tobramycin therapy.
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Adapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era.
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Adjunct Therapies for Refractory Status Asthmaticus in Children.
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Aerosol and other novel administrations for prevention and treatment of invasive aspergillosis.
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Aerosolized antifungal prophylaxis: the winds of change?
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Aerosolized ribavirin in the treatment of patients with respiratory syncytial virus disease.
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Aerosolized ribavirin: the most expensive drug for pneumonia.
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Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.
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Airway sensory replacement combined with nicotine replacement for smoking cessation. A randomized, placebo-controlled trial using a citric acid inhaler.
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Allogeneic splenocyte transfer and lipopolysaccharide inhalations induce differential T cell expansion and lung injury: a novel model of pulmonary graft-versus-host disease.
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Alveolar type II cell responses to chronic inhalation of chrysotile asbestos in rats.
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An Asthma Protocol Improved Adherence to Evidence-Based Guidelines for Pediatric Subjects With Status Asthmaticus in the Emergency Department.
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Anticholinergic vs Long-Acting β-Agonist in Combination With Inhaled Corticosteroids in Black Adults With Asthma: The BELT Randomized Clinical Trial.
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Assessing acute systemic effects of an inhaled drug with serial echocardiography: a placebo-controlled comparison of inhaled and intravenous dihydroergotamine.
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Association of Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists With Asthma Control in Patients With Uncontrolled, Persistent Asthma: A Systematic Review and Meta-analysis.
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Association of Inhaled Corticosteroids and Long-Acting β-Agonists as Controller and Quick Relief Therapy With Exacerbations and Symptom Control in Persistent Asthma: A Systematic Review and Meta-analysis.
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Atrial and brain natriuretic peptide concentrations and the response to inhaled nitric oxide in patients with acute respiratory distress syndrome.
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Balancing the benefits and risks of inhaled long-acting beta-agonists--the influence of values.
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Beneficial effects of albuterol therapy driven by heliox versus by oxygen in severe asthma exacerbation.
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Biomarkers to Predict Response to Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists in Adolescents and Adults with Mild Persistent Asthma.
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Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans.
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Candida pneumonia in a term infant after prolonged use of inhaled corticosteroids for bronchopulmonary dysplasia (BPD).
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Candidal anastomotic infection in lung transplant recipients: successful treatment with a combination of systemic and inhaled antifungal agents.
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Carcinogenicity and toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats.
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Carcinogenicity of inhaled benzene in CBA mice.
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Central nervous system distribution of inhaled toluene.
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Cerebral blood volume measured with inhaled C15O and positron emission tomography.
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Cerebral vasodilation and vasoconstriction associated with acute anxiety.
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Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis.
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Chloroform inhalation exposure conditions necessary to initiate liver toxicity in female B6C3F1 mice.
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Chronic inhalation study of fiber glass and amosite asbestos in hamsters: twelve-month preliminary results.
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Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice.
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Clinical effects of methamphetamine vapor inhalation.
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Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosis.
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Comparison of Inhaled Drug Delivery in Patients With One- and Two-level Laryngotracheal Stenosis.
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Comparison of inhaled isopropyl alcohol and intravenous ondansetron for treatment of postoperative nausea.
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Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers.
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Comparison of pulmonary and pleural responses of rats and hamsters to inhaled refractory ceramic fibers.
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Comparison of systemic and mucosal vaccination: impact on intravenous and rectal SIV challenge.
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Comparison of the efficacy and safety of arformoterol 15 microg twice daily and arformoterol 30 microg once daily in COPD: a single-dose, multicenter, randomized, modified-blind, two-way crossover study.
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Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents.
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Consensus summary of aerosolized antimicrobial agents: application of guideline criteria. Insights from the Society of Infectious Diseases Pharmacists.
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Contribution of magnetic resonance microscopy in the 12-week neurotoxicity evaluation of carbonyl sulfide in Fischer 344 rats.
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Corticosteroid Therapy During Acute Bronchiolitis in Patients Who Later Develop Asthma.
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Diffusion-weighted hyperpolarized 129Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease.
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Direct measurement of lung motion using hyperpolarized helium-3 MR tagging.
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Dispensing home nebulizers for acute wheezing from the hospital is cost-effective.
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Does improved oxygenation really imply increased benefit?
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Dose and pulse sequence considerations for hyperpolarized (129)Xe ventilation MRI.
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Double-ring esophageal sign: pathognomonic for esophageal lipomatosis.
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Early management of acute severe asthma.
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Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial.
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Effect of lipopolysaccharide administration on the number, phenotype and content of nuclear molecules in blood microparticles of normal human subjects.
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Effect of nitrous oxide on cerebral blood velocity while reclining and standing.
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Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial.
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Effects of ethanol on plasma ghrelin levels in the rat during early and late adolescence.
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Effects of immobilization restraint on Syrian golden hamsters.
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Effects of inhaled CO administration on acute lung injury in baboons with pneumococcal pneumonia.
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Effects of kindling on subsequent learning, memory, behavior, and seizure susceptibility.
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Effects of p-xylene inhalation on axonal transport in the rat retinal ganglion cells.
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Effects of quisqualic acid and glutamate on subsequent learning, emotionality, and seizure susceptibility in the immature and mature animal.
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Efficacy of esomeprazole for treatment of poorly controlled asthma.
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Elevation of rat pulmonary, hepatic and lung surfactant lipids by fly ash inhalation.
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Enabling hyperpolarized (129) Xe MR spectroscopy and imaging of pulmonary gas transfer to the red blood cells in transgenic mice expressing human hemoglobin.
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Endobronchial injection of botulinum toxin for the reduction of bronchial hyperreactivity induced by methacholine inhalation in dogs.
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Endotracheal flumazenil: a new route of administration for benzodiazepine antagonism.
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Epithelial injury and interstitial fibrosis in the proximal alveolar regions of rats chronically exposed to a simulated pattern of urban ambient ozone.
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Extrapulmonary effects of inhaled nitric oxide: role of reversible S-nitrosylation of erythrocytic hemoglobin.
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Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment.
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Fibrous glass and cancer.
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First In-Human Experience With Inhaled Acetylsalicylic Acid for Immediate Platelet Inhibition: Comparison With Chewed and Swallowed Acetylsalicylic Acid.
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Five percent CO₂ is a potent, fast-acting inhalation anticonvulsant.
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Formaldehyde concentrations in the blood of rhesus monkeys after inhalation exposure.
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Gasoline sniffing multifocal neuropathy.
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Genes of innate immunity and the biological response to inhaled ozone.
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Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999.
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High prevalence of substance use disorders among adolescents who use marijuana and inhalants.
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Hyaluronan fragments contribute to the ozone-primed immune response to lipopolysaccharide.
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In acute lung injury, inhaled nitric oxide improves ventilation-perfusion matching, pulmonary vascular mechanics, and transpulmonary vascular efficiency.
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In vitro characterization of nebulizer delivery of liposomal amphotericin B aerosols.
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Individualized therapy for persistent asthma in young children.
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Induction of pulmonary and hepatic cytochrome P-450 species by coal fly ash inhalation in rats.
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Infectious diseases of the upper respiratory tract: implications for toxicology studies.
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Inhalant abuse and dependence among adolescents in the United States.
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Inhalant use and disorders among adults in the United States.
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Inhalation of vapor from black pepper extract reduces smoking withdrawal symptoms.
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Inhaled Desmopressin for Refractory Gastrointestinal Bleeding in a Patient With a HeartMate II Left Ventricular Assist Device.
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Inhaled Iloprost Versus Epoprostenol in Heart Transplant Recipients.
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Inhaled Nitric Oxide (iNO) and Inhaled Epoprostenol (iPGI2) Use in Cardiothoracic Surgical Patients: Is there Sufficient Evidence for Evidence-Based Recommendations?
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Inhaled PGE1 in neonates with hypoxemic respiratory failure: two pilot feasibility randomized clinical trials.
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Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant: A Randomized Clinical Trial.
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Inhaled azithromycin therapy.
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Inhaled corticosteroids in obstructive airway disease.
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Inhaled epoprostenol during one-lung ventilation.
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Inhaled ethyl nitrite gas for persistent pulmonary hypertension in infants.
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Inhaled ethyl nitrite gas for persistent pulmonary hypertension of the newborn.
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Inhaled ethyl nitrite prevents hyperoxia-impaired postnatal alveolar development in newborn rats.
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Inhaled fentanyl aerosol in healthy volunteers: pharmacokinetics and pharmacodynamics.
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Inhaled nitric oxide after left ventricular assist device implantation: a prospective, randomized, double-blind, multicenter, placebo-controlled trial.
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Inhaled nitric oxide selectively dilates pulmonary vasculature in adult patients with pulmonary hypertension, irrespective of etiology.
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Inhaled nitric oxide therapy increases blood nitrite, nitrate, and s-nitrosohemoglobin concentrations in infants with pulmonary hypertension.
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Inhaled short-acting beta2-agonists versus ipratropium for acute exacerbations of chronic obstructive pulmonary disease.
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Inhaled steroids as prophylaxis for delayed pulmonary toxicity syndrome in breast cancer patients undergoing high-dose chemotherapy and autologous stem cell transplantation.
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Initial characterization of micafungin pulmonary delivery via two different nebulizers and multivariate data analysis of aerosol mass distribution profiles.
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Intracranial and extracranial blood flow during acute anxiety.
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Intraoperative use of inhaled PGI(2) for acute pulmonary hypertension and right ventricular failure.
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Intratracheal catheters as drug delivery systems.
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Is inhalant use a risk factor for heroin and injection drug use among adolescents in the United States?
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Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin.
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Levodopa inhalation powder in a patient with persistent asthma.
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Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice.
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Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles.
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Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation.
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Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.
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Management Practice and Mortality for Infants with Congenital Diaphragmatic Hernia.
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Measurement reliability of highly variable physiological responses to experimentally-manipulated gas fractions.
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Mechanical ventilation strategies in the management of congenital diaphragmatic hernia.
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Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice.
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Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level.
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Nasally inhaled dornase alfa in the postoperative management of chronic sinusitis due to cystic fibrosis.
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Nebulized prostacyclin for pulmonary hypertension: a step in the right direction.
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Nebulizer delivery of micafungin aerosols.
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Numerical evaluation of spray position for improved nasal drug delivery.
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Oral and Inhaled Ribavirin Treatment for Respiratory Syncytial Virus Infection in Lung Transplant Recipients.
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Orally Inhaled Drug Particle Transport in Computerized Models of Laryngotracheal Stenosis.
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Overweight/obesity status in preschool children associates with worse asthma but robust improvement on inhaled corticosteroids.
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Ozone primes alveolar macrophage-derived innate immunity in healthy human subjects.
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PINOT NOIR: pulmonic insufficiency improvement with nitric oxide inhalational response.
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Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma.
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Pharmacokinetic modeling of the lung burden from repeated inhalation of nickel aerosols.
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Pharmacokinetics of methamphetamine self-administered to human subjects by smoking S-(+)-methamphetamine hydrochloride.
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Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage.
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Pleural dosimetry and pathobiological responses in rats and hamsters exposed subchronically to MMVF 10a fiberglass.
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Pleural effects of indium phosphide in B6C3F1 mice: nonfibrous particulate induced pleural fibrosis.
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Preferences and Stated Adherence for Antibiotic Treatment of Cystic Fibrosis Pseudomonas Infections.
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Preparation of in vivo cleavable agglomerated liposomes suitable for modulated pulmonary drug delivery.
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Prevention and management of bronchopulmonary dysplasia: Lessons learned from the neonatal research network.
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Protection from lipopolysaccharide-induced lung injury by augmentation of airway S-nitrosothiols.
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Protocolized approach to the management of congenital diaphragmatic hernia: benefits of reducing variability in care.
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Psychiatric disorders in inhalant users: results from The National Epidemiologic Survey on Alcohol and Related Conditions.
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Pulmonary Delivery of Therapeutic and Diagnostic Gases.
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Pulmonary and pleural leukocytes from F344 rats produce elevated levels of fibronectin following inhalation of refractory ceramic fibers.
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Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. I. Quantitation of lung and pleural fiber burdens.
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Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. II. Pathobiologic responses.
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Pulmonary fibrogenesis after three consecutive inhalation exposures to chrysotile asbestos.
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Pulmonary kinematics from tagged hyperpolarized helium-3 MRI.
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Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles.
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Pyrolytic characteristics, pharmacokinetics, and bioavailability of smoked heroin, cocaine, phencyclidine, and methamphetamine.
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Quantifying asthma patient preferences for onset of effect of combination inhaled corticosteroids and long-acting beta2-agonist maintenance medications.
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Quantifying the importance of inhaler attributes corresponding to items in the patient satisfaction and preference questionnaire in patients using Combivent Respimat.
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Quantitative analysis of hyperpolarized 3He ventilation changes in mice challenged with methacholine.
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Quantitative models of the dose-response and time course of inhalational anthrax in humans.
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Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations.
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Radiation absorbed dose estimates for oxygen-15 radiopharmaceuticals (H2(15)O, C15O, O15O) in newborn infants.
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Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn.
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Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury.
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Reduction in pulmonary and hepatic respiratory cytochrome contents by fly ash inhalation in rats.
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Regional Gas Exchange Measured by 129 Xe Magnetic Resonance Imaging Before and After Combination Bronchodilators Treatment in Chronic Obstructive Pulmonary Disease.
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Regional cerebral blood flow changes associated with amyl nitrite inhalation.
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Reliever-Triggered Inhaled Glucocorticoid in Black and Latinx Adults with Asthma.
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Respiratory Medications in Infants <29 Weeks during the First Year Postdischarge: The Prematurity and Respiratory Outcomes Program (PROP) Consortium.
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Respiratory care year in review 2010: part 2. Invasive mechanical ventilation, noninvasive ventilation, pediatric mechanical ventilation, aerosol therapy.
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Respiratory controversies in the critical care setting. Conference summary.
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Respiratory therapies in the critical care setting. Should aerosolized antibiotics be administered to prevent or treat ventilator-associated pneumonia in patients who do not have cystic fibrosis?
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Risk factors for COPD exacerbations in inhaled medication users: the COPDGene study biannual longitudinal follow-up prospective cohort.
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Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV.
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S-nitrosoglutathione supplementation to ovalbumin-sensitized and -challenged mice ameliorates methacholine-induced bronchoconstriction.
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S-nitrosothiol repletion by an inhaled gas regulates pulmonary function.
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Safety and Tolerability of High-dose Inhaled Treprostinil in Pulmonary Hypertension.
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Safety and tolerability of transition from inhaled treprostinil to oral selexipag in pulmonary arterial hypertension: Results from the TRANSIT-1 study.
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Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos.
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Standard care versus protocol based therapy for new onset Pseudomonas aeruginosa in cystic fibrosis.
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Standardization of the single-breath diffusing capacity in a multicenter clinical trial.
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Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma.
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Street and working children of Delhi, India, misusing toluene: an ethnographic exploration.
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Technosphere insulin: inhaled prandial insulin.
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The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase.
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The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide.
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The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation.
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The effects of hyperoxic and hypercarbic gases on tumour blood flow.
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The hematological effects of nitrous oxide anesthesia in pediatric patients.
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The neuroprotective effect of xenon administration during transient middle cerebral artery occlusion in mice.
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The response to inhaled nitric oxide in patients with pulmonary artery hypertension is not masked by baseline vasodilator use.
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The spontaneously hypertensive rat: an experimental model of sulfur dioxide-induced airways disease.
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The use of supplemental hydrocortisone in the management of persistent pulmonary hypertension of the newborn.
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Therapeutic effect of infused Fluosol-DA/carbogen with ephedrine, flunarizine, or nitroprusside.
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Time to question long-term safety of routine scheduled inhaled beta-2-agonist treatment for COPD.
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Tiotropium (Spiriva) for COPD.
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Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide.
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Transpulmonary flux of S-nitrosothiols and pulmonary vasodilation during nitric oxide inhalation: role of transport.
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Two Cases Comparing the Presentations and Outcomes of Heroin-induced Toxic Leukoencephalopathy.
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Unilateral supraglottitis in adults: fact or fiction.
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Unique cellular and humoral immunogenicity profiles generated by aerosol, intranasal, or parenteral vaccination in rhesus macaques.
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Use of aerosolized inhaled epoprostenol in the treatment of portopulmonary hypertension.
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Use of lung toxicity and lung particle clearance to estimate the maximum tolerated dose (MTD) for a fiber glass chronic inhalation study in the rat.
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Use of nitrite inhalants ("poppers") among American youth.
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Utilization of inhaled nitric oxide after surgical repair of truncus arteriosus: A multicenter analysis.
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Value of an inhalational model of invasive aspergillosis.
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Variability in blood flow and pO2 in tumors in response to carbogen breathing.
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Variations in Prkdc and susceptibility to benzene-induced toxicity in mice.
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Ventilation/perfusion imaging in a rat model of airway obstruction.
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Vestibulotoxicity in a patient without renal failure after inhaled tobramycin.
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Wood smoke particle exposure in mice reduces the severity of influenza infection.
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alpha 2u-Globulin nephropathy, renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats.
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Keywords of People
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Chen, Jun,
Professor of Medicine,
Duke Cancer Institute
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Driehuys, Bastiaan,
Professor of Radiology,
Biomedical Engineering
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Wu, Li-Tzy,
Professor in Psychiatry and Behavioral Sciences,
Medicine, General Internal Medicine