Administration, Intranasal
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Subject Areas on Research
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A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques.
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A comparison of non-toxin vaccine adjuvants for their ability to enhance the immunogenicity of nasally-administered anthrax recombinant protective antigen.
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A computational study of functional endoscopic sinus surgery and maxillary sinus drug delivery.
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A novel neurotoxoid vaccine prevents mucosal botulism.
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A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.
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Adenovirus F protein as a delivery vehicle for botulinum B.
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Biodegradable nanoparticle-entrapped vaccine induces cross-protective immune response against a virulent heterologous respiratory viral infection in pigs.
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CaMKII is essential for the proasthmatic effects of oxidation.
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Capric acid and hydroxypropylmethylcellulose increase the immunogenicity of nasally administered peptide vaccines.
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Cocaine disposition in humans after intravenous injection, nasal insufflation (snorting), or smoking.
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Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study.
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Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial.
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Comparison of multiple vaccine vectors in a single heterologous prime-boost trial.
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Computed intranasal spray penetration: comparisons before and after nasal surgery.
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Contrasting response of lung parenchymal cells to instilled TNF alpha and IFN gamma: the inducibility of specific cell ICAM-1 in vivo.
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Control of simian/human immunodeficiency virus viremia and disease progression after IL-2-augmented DNA-modified vaccinia virus Ankara nasal vaccination in nonhuman primates.
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Cross-protective immunity to porcine reproductive and respiratory syndrome virus by intranasal delivery of a live virus vaccine with a potent adjuvant.
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Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization.
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Cytokines as adjuvants for the induction of anti-human immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization.
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Cytokines: the future of intranasal vaccine adjuvants.
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DNA-MVA vaccine protection after X4 SHIV challenge in macaques correlates with day-of-challenge antiviral CD4+ cell-mediated immunity levels and postchallenge preservation of CD4+ T cell memory.
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Development of a novel adjuvanted nasal vaccine: C48/80 associated with chitosan nanoparticles as a path to enhance mucosal immunity.
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Deviated nasal septum hinders intranasal sprays: a computer simulation study.
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Disposition of nasal, intravenous, and oral methadone in healthy volunteers.
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Effect of particulate adjuvant on the anthrax protective antigen dose required for effective nasal vaccination.
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Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1.
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Effects of intranasal administration of norethisterone on folliculogenesis, cervical mucus, vaginal cytology, endometrial morphology and reproductive-endocrine profile in women.
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Effects of oxytocin administration on spirituality and emotional responses to meditation.
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Efficacy of intranasal corticosteroids for acute sinusitis.
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Efficacy trial of live, cold-adapted and inactivated influenza virus vaccines in older adults with chronic obstructive pulmonary disease: a VA cooperative study.
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Enhanced Immune Responses to HIV-1 Envelope Elicited by a Vaccine Regimen Consisting of Priming with Newcastle Disease Virus Expressing HIV gp160 and Boosting with gp120 and SOSIP gp140 Proteins.
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Epidemiology and risk factors for recurrent Staphylococcus aureus colonization following active surveillance and decolonization in the NICU.
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Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6).
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Identification of early interactions between Francisella and the host.
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Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routes.
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In vitro bioequivalence testing.
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Increased subjective and reinforcing effects of initial nicotine exposure in young adults with attention deficit hyperactivity disorder (ADHD) compared to matched peers: results from an experimental model of first-time tobacco use.
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Initial pharmacokinetic, safety and efficacy evaluation of nasal morphine gluconate for breakthrough pain in cancer patients.
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Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits (Oryctolagus cuniculus).
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Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes.
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Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder.
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Intranasal clonidine as a premedicant: three cases with unique indications.
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Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses.
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Intranasal delivery of an adjuvanted modified live porcine reproductive and respiratory syndrome virus vaccine reduces ROS production.
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Intranasal delivery of whole cell lysate of Mycobacterium tuberculosis induces protective immune responses to a modified live porcine reproductive and respiratory syndrome virus vaccine in pigs.
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Intranasal fentanyl improves time to analgesic delivery in sickle cell pain crises.
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Intranasal fluticasone associated with delayed tympanostomy tube placement in children with eustachian tube dysfunction.
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Intranasal immunization is superior to vaginal, gastric, or rectal immunization for the induction of systemic and mucosal anti-HIV antibody responses.
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Intranasal immunization with CTL epitope peptides from HIV-1 or ovalbumin and the mucosal adjuvant cholera toxin induces peptide-specific CTLs and protection against tumor development in vivo.
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Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity.
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Intranasal midazolam and fentanyl for procedural sedation and analgesia in infants in the neonatal intensive care unit.
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Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice.
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Intranasal vaccination with the recombinant Listeria monocytogenes ΔactA prfA* mutant elicits robust systemic and pulmonary cellular responses and secretory mucosal IgA.
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Long-term control of simian immunodeficiency virus mac251 viremia to undetectable levels in half of infected female rhesus macaques nasally vaccinated with simian immunodeficiency virus DNA/recombinant modified vaccinia virus Ankara.
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Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium.
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Mucosal and systemic anti-HIV responses in rhesus macaques following combinations of intranasal and parenteral immunizations.
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Mucosal immunity to HIV-1: systemic and vaginal antibody responses after intranasal immunization with the HIV-1 C4/V3 peptide T1SP10 MN(A).
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Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits.
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Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A.
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Mucosally-administered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIVSF162P3.
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Murine model of pulmonary anthrax: kinetics of dissemination, histopathology, and mouse strain susceptibility.
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Mycobacterium tuberculosis whole cell lysate enhances proliferation of CD8 positive lymphocytes and nitric oxide secretion in the lungs of live porcine respiratory and reproductive syndrome virus vaccinated pigs.
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Nasal DNA-MVA SIV vaccination provides more significant protection from progression to AIDS than a similar intramuscular vaccination.
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Nasal Immunization With Small Molecule Mast Cell Activators Enhance Immunity to Co-Administered Subunit Immunogens.
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Nasal administration of opioids for pain management in adults.
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Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces Th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates.
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Nasal peptide vaccination elicits CD8 responses and reduces viral burden after challenge with virulent murine cytomegalovirus.
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Nasal tetracaine spray-induced methemoglobinemia.
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Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury.
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Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses.
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Nicotine for postoperative analgesia: a systematic review and meta-analysis.
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Novel dry powder preparations of whole inactivated influenza virus for nasal vaccination.
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Novel intranasal pertussis vaccine based on bacterium-like particles as a mucosal adjuvant.
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Numerical evaluation of spray position for improved nasal drug delivery.
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Optimized Mucosal Modified Vaccinia Virus Ankara Prime/Soluble gp120 Boost HIV Vaccination Regimen Induces Antibody Responses Similar to Those of an Intramuscular Regimen.
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Ozone inhalation promotes CX3CR1-dependent maturation of resident lung macrophages that limit oxidative stress and inflammation.
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PLGA nanoparticle entrapped killed porcine reproductive and respiratory syndrome virus vaccine helps in viral clearance in pigs.
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Porcine reproductive and respiratory syndrome virus induces pronounced immune modulatory responses at mucosal tissues in the parental vaccine strain VR2332 infected pigs.
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Prevention of middle ear barotrauma with oxymetazoline/fluticasone treatment.
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Prevention of surgical-site infections.
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Protection of macaques against vaginal SHIV challenge by systemic or mucosal and systemic vaccinations with HIV-envelope.
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Randomized trial comparing the safety and antibody responses to live attenuated versus inactivated influenza vaccine when administered to breastfeeding women.
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Rationale, design, and methods of the Autism Centers of Excellence (ACE) network Study of Oxytocin in Autism to improve Reciprocal Social Behaviors (SOARS-B).
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Selective use of intranasal mupirocin and chlorhexidine bathing and the incidence of methicillin-resistant Staphylococcus aureus colonization and infection among intensive care unit patients.
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Stable dry powder formulation for nasal delivery of anthrax vaccine.
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Study of the role of CCR5 in a mouse model of intranasal challenge with Yersinia pestis.
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The effects of intranasal oxytocin on reward circuitry responses in children with autism spectrum disorder.
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The misuse and diversion of prescribed ADHD medications by college students.
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The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections.
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Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format.
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Treatment of hyperkalaemia using intravenous and nebulised salbutamol.
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Underwater nasal decongestant use: a novel approach to middle ear equalization.
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Unique cellular and humoral immunogenicity profiles generated by aerosol, intranasal, or parenteral vaccination in rhesus macaques.
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Use of 1-desamino-8-D-arginine vasopressin in microsurgical reconstruction in a patient with von Willebrand's disease.
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Keywords of People