Administration, Intravaginal

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  Subject Areas on Research

  • "Set it and forget it": women's perceptions and opinions of long-acting topical vaginal gels. 
  • A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251. 
  • Acceptability of microbicidal vaginal rings and oral pre-exposure prophylaxis for HIV prevention among female sex workers in a high-prevalence US city. 
  • Analysis of vaginal microbicide film hydration kinetics by quantitative imaging refractometry. 
  • Bacterial vaginosis-associated microflora and effects of topical intravaginal clindamycin. 
  • Bacterial vaginosis: diagnostic and pathogenetic findings during topical clindamycin therapy. 
  • Bacterial vaginosis: treatment with topical intravaginal clindamycin phosphate. 
  • Biophysical analysis of prototype microbicidal gels. 
  • Cervical Cerclage versus Vaginal Progesterone for Management of Short Cervix in Low-Risk Women. 
  • Cervical ripening: randomized comparison of intravaginal prostaglandin E2 gel with prostaglandin E2 gel plus laminaria tents. 
  • Cervical screening and general physical examination behaviors of women exposed in utero to diethylstilbestrol. 
  • Clinical use of oral contraceptives administered vaginally: a case report. 
  • Compartmental transport model of microbicide delivery by an intravaginal ring. 
  • Computer modeling informs study design: vaginal estrogen to prevent mesh erosion after different routes of prolapse surgery. 
  • Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses. 
  • Control of viremia and maintenance of intestinal CD4(+) memory T cells in SHIV(162P3) infected macaques after pathogenic SIV(MAC251) challenge. 
  • Deducing Mucosal Pharmacokinetics and Pharmacodynamics of the Anti-HIV Molecule Tenofovir from Measurements in Blood. 
  • Designing Dual Compartment HIV Prevention Products: Women's Sensory Perceptions and Experiences of Suppositories for Rectal and Vaginal Use. 
  • Designing preclinical perceptibility measures to evaluate topical vaginal gel formulations: relating user sensory perceptions and experiences to formulation properties. 
  • Dynamics of HIV neutralization by a microbicide formulation layer: biophysical fundamentals and transport theory. 
  • Effect of vaginal lubricants on natural fertility. 
  • Evaluation of recombinant adenovirus vaccines based on glycoprotein D and truncated UL25 against herpes simplex virus type 2 in mice. 
  • Gravity-induced coating flows of vaginal gel formulations: in vitro experimental analysis. 
  • Interferon lambda protects the female reproductive tract against Zika virus infection. 
  • Label-free analysis of tenofovir delivery to vaginal tissue using co-registered confocal Raman spectroscopy and optical coherence tomography. 
  • Long-term control of simian immunodeficiency virus mac251 viremia to undetectable levels in half of infected female rhesus macaques nasally vaccinated with simian immunodeficiency virus DNA/recombinant modified vaccinia virus Ankara. 
  • Management of Menopausal Symptoms for Women Who Are at High Risk of Thrombosis. 
  • Management of Short Cervix during Pregnancy: A Review. 
  • Mesenteric vein thrombosis associated with intravaginal contraceptives: a case report and review of the literature. 
  • Multivalent benzoboroxole functionalized polymers as gp120 glycan targeted microbicide entry inhibitors. 
  • Optical imaging and analysis of human vaginal coating by drug delivery gels 
  • PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial. 
  • Rhesus macaques that become systemically infected with pathogenic SHIV 89.6-PD after intravenous, rectal, or vaginal inoculation and fail to make an antiviral antibody response rapidly develop AIDS. 
  • Semi-solid gels function as physical barriers to human immunodeficiency virus transport in vitro. 
  • Serum progesterone levels following vaginal administration of progesterone during the luteal phase. 
  • Simian-human immunodeficiency virus SHIV89.6-induced protection against intravaginal challenge with pathogenic SIVmac239 is independent of the route of immunization and is associated with a combination of cytotoxic T-lymphocyte and alpha interferon responses. 
  • Temperature and pH sensitive hydrogels: an approach towards smart semen-triggered vaginal microbicidal vehicles. 
  • The Role of Volume in the Perceptibility of Topical Vaginal Formulations: User Sensory Perceptions and Experiences of Heterosexual Couples During Vaginal Sex. 
  • The Urinary Microbiome in Postmenopausal Women with Recurrent Urinary Tract Infections. 
  • The rational design and development of a dual chamber vaginal/rectal microbicide gel formulation for HIV prevention. 
  • Transport theory for HIV diffusion through in vivo distributions of topical microbicide gels. 
  • Use of the levonorgestrel-releasing intrauterine system in women with hemostatic disorders. 
  • User-identified gel characteristics: a qualitative exploration of perceived product efficacy of topical vaginal microbicides. 
  • Vaginal administration of low-dose conjugated estrogens: systemic absorption and effects on the endometrium. 
  • Vaginal distribution of Replens and K-Y Jelly using three imaging techniques. 
  • Vaginal film for prevention of HIV: using visual and tactile evaluations among potential users to inform product design. 
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  Keywords of People

  • Katz, David F., Nello L. Teer, Jr. Distinguished Professor of Biomedical Engineering, in the Edmund T. Pratt, Jr. School of Engineering, Biomedical Engineering