Administration, Oral

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  Subject Areas on Research

  • "Take your pill": the role and fantasy of pills in modern medicine. 
  • 3,4-Diaminopyridine (DAP) in the treatment of Lambert-Eaton myasthenic syndrome (LEMS). 
  • 9-Nitrocamptothecin as second line chemotherapy for men with progressive, metastatic, hormone refractory prostate cancer: Results of the CALGB 99901. 
  • A Bridge to Nowhere? Benefits and Risks for Periprocedural Anticoagulation in Atrial Fibrillation. 
  • A Phase I safety and immunogenicity trial of UBI microparticulate monovalent HIV-1 MN oral peptide immunogen with parenteral boost in HIV-1 seronegative human subjects. 
  • A Phase I trial of preoperative eniluracil plus 5-fluorouracil and radiation for locally advanced or unresectable adenocarcinoma of the rectum and colon. 
  • A Phase II feasibility study of oral etoposide given concurrently with radiotherapy followed by dose intensive adjuvant chemotherapy for children with newly diagnosed high-risk medulloblastoma (protocol POG 9631): A report from the Children's Oncology Group. 
  • A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents. 
  • A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics. 
  • A Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis. 
  • A clinical trial of oral therapy in a rural cholera-treatment center. 
  • A clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT-AF): design and rationale. 
  • A comparison of oral and rectal absorption of L-dopa esters in rats and mice. 
  • A comparison of three doses of a commercially prepared oral midazolam syrup in children. 
  • A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis. 
  • A direct correlation of the resolution of pseudophakic cystoid macular edema with acetazolamide therapy. 
  • A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice. 
  • A meta-analysis of zinc salts lozenges and the common cold. 
  • A mouse bleeding model to study oral anticoagulants. 
  • A multicenter trial of oral zidovudine in children with advanced human immunodeficiency virus disease. The Protocol 043 Study Group. 
  • A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia. 
  • A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation (IMPACT-AF): an international, cluster-randomised trial. 
  • A new instrument for measuring anticoagulation-related quality of life: development and preliminary validation. 
  • A non-experimental study of oral anticoagulation therapy initiation before and after national patient safety goals. 
  • A novel approach to maintain gut mucosal integrity using an oral enzyme supplement. 
  • A novel neurotoxoid vaccine prevents mucosal botulism. 
  • A pharmacodynamic study of rapamycin in men with intermediate- to high-risk localized prostate cancer. 
  • A phase 2 study of KX2-391, an oral inhibitor of Src kinase and tubulin polymerization, in men with bone-metastatic castration-resistant prostate cancer. 
  • A phase 3, placebo controlled study of the safety and efficacy of avanafil for the treatment of erectile dysfunction after nerve sparing radical prostatectomy. 
  • A phase I and pharmacokinetic study of oral lapatinib administered once or twice daily in patients with solid malignancies. 
  • A phase I multicenter study of continuous oral administration of lonafarnib (SCH 66336) and intravenous gemcitabine in patients with advanced cancer. 
  • A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection. 
  • A phase I/II trial of TAC-101, an oral synthetic retinoid, in patients with advanced hepatocellular carcinoma. 
  • A phase II Hoosier Oncology Group study of vinorelbine and estramustine phosphate in hormone-refractory prostate cancer. 
  • A phase II study of 2-methoxyestradiol (2ME2) NanoCrystal® dispersion (NCD) in patients with taxane-refractory, metastatic castrate-resistant prostate cancer (CRPC). 
  • A physiologic role for somatostatin 28 as a regulator of insulin secretion. 
  • A pilot study assessing pharmacokinetics and tolerability of oral and intravenous baclofen in healthy adult volunteers. 
  • A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: the treatment of Early Aggressive Rheumatoid Arthritis Trial. 
  • A randomized trial to compare intravenous and oral etoposide in combination with cisplatin for the treatment of small cell lung cancer. 
  • A randomized, controlled trial of corticosteroids in the treatment of acute optic neuritis. The Optic Neuritis Study Group. 
  • A randomized, double-blind phase 2 study comparing the efficacy and safety of an oral fusidic acid loading-dose regimen to oral linezolid for the treatment of acute bacterial skin and skin structure infections. 
  • A randomized, double-blind, active-controlled phase 2 trial to evaluate a novel selective and reversible intravenous and oral P2Y12 inhibitor elinogrel versus clopidogrel in patients undergoing nonurgent percutaneous coronary intervention: the INNOVATE-PCI trial. 
  • A randomized, double-blind, placebo-controlled dose-escalation trial of merimepodib (VX-497) and interferon-alpha in previously untreated patients with chronic hepatitis C. 
  • A randomized, placebo-controlled trial of the safety and efficacy of oral ganciclovir for prophylaxis of cytomegalovirus disease in HIV-infected individuals. Terry Beirn Community Programs for Clinical Research on AIDS. 
  • A review of the health impacts of barium from natural and anthropogenic exposure. 
  • A single dose of live oral cholera vaccine CVD 103-HgR is safe and immunogenic in HIV-infected and HIV-noninfected adults in Mali. 
  • Abdomen after a Puestow procedure: postoperative CT appearance, complications, and potential pitfalls. 
  • Abiraterone acetate for patients with metastatic castration-resistant prostate cancer progressing after chemotherapy: final analysis of a multicentre, open-label, early-access protocol trial. 
  • Absence of Oral Anticoagulation and Subsequent Outcomes Among Outpatients with Atrial Fibrillation. 
  • Absence of delayed neurotoxicity and increased plasma butyrylcholinesterase activity in triallate-treated hens. 
  • Absence of detectable pharmacological effects after oral administration of isoxsuprine. 
  • Absorption, distribution, and elimination of a single oral dose of [14C]tri-o-cresyl phosphate in hens. 
  • Absorption, distribution, excretion and metabolism of a single oral dose of [14C]tri-o-cresyl phosphate (TOCP) in the male rat. 
  • Absorption, distribution, metabolism and excretion of daily oral doses of [14C]methyl parathion in hens. 
  • Accurate Dosing of Antiretrovirals at Home Using a Foilized, Polyethylene Pouch to Prevent the Transmission of HIV From Mother to Child. 
  • Acute and chronic dosing of lepidium meyenii (Maca) on male rat sexual behavior 
  • Acute management of stroke patients taking non-vitamin K antagonist oral anticoagulants Addressing Real-world Anticoagulant Management Issues in Stroke (ARAMIS) Registry: Design and rationale. 
  • Acute oral 18-methoxycoronaridine (18-MC) decreases both alcohol intake and IV nicotine self-administration in rats. 
  • Acyclovir-resistant herpes simplex virus keratouveitis after penetrating keratoplasty. 
  • Adaptation after small bowel resection is attenuated by sialoadenectomy: the role for endogenous epidermal growth factor. 
  • Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial. 
  • Addressing barriers to optimal oral anticoagulation use and persistence among patients with atrial fibrillation: Proceedings, Washington, DC, December 3-4, 2012. 
  • Adherence and persistence with oral adjuvant chemotherapy in older women with early-stage breast cancer in CALGB 49907: adherence companion study 60104. 
  • Adherence to Oral Therapy for Urgency Urinary Incontinence: Results from the Anticholinergic Versus Botox Comparison (ABC) Trial. 
  • Adherence to Rivaroxaban Compared with Other Oral Anticoagulant Agents Among Patients with Nonvalvular Atrial Fibrillation. 
  • Adherence to Third European Cooperative Acute Stroke Study 3- to 4.5-hour exclusions and association with outcome: data from Get with the Guidelines-Stroke. 
  • Adjuvant therapy for colorectal cancer: yesterday, today, and tomorrow. 
  • Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex. 
  • Administration of oral acyclovir suppressive therapy after neonatal herpes simplex virus disease limited to the skin, eyes and mouth: results of a phase I/II trial. 
  • Adverse Events With Sustained-Release Donepezil in Alzheimer Disease: Relation to Body Mass Index. 
  • Adverse event management in patients with advanced cancer receiving oral everolimus: focus on breast cancer. 
  • Allopregnanolone elevations following pregnenolone administration are associated with enhanced activation of emotion regulation neurocircuits. 
  • Alteration of digoxin pharmacokinetics by a single dose of quinidine. 
  • Alternating ibuprofen and acetaminophen in the treatment of febrile children: a pilot study [ISRCTN30487061]. 
  • An open-label, randomized, controlled, multicenter study exploring two treatment strategies of rivaroxaban and a dose-adjusted oral vitamin K antagonist treatment strategy in subjects with atrial fibrillation who undergo percutaneous coronary intervention (PIONEER AF-PCI). 
  • Anticholinergic versus botulinum toxin A comparison trial for the treatment of bothersome urge urinary incontinence: ABC trial. 
  • Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial. 
  • Anticoagulants. 
  • Anticoagulation strategies for the management of postoperative atrial fibrillation. 
  • Antidiabetic potential of Barleria lupulina extract in rats. 
  • Antioxidant response to exercise-induced oxidative stress and protection by vitamin E. 
  • Antiplatelet and anticoagulant agents in heart failure: current status and future perspectives. 
  • Antithrombotic agents for secondary prevention after acute coronary syndromes: A systematic review and network meta-analysis. 
  • Antithrombotic therapies in patients with prosthetic heart valves: guidelines translated for the clinician. 
  • Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. 
  • Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models. 
  • Antitussive potential of methanol extract of stem bark of Ficus racemosa Linn. 
  • Antiviral activity of mixed-valence rare earth borotungstate heteropoly blues against influenza virus in mice. 
  • Apixaban to prevent stroke in patients with atrial fibrillation: a review. 
  • Apixaban vs. warfarin with concomitant aspirin in patients with atrial fibrillation: insights from the ARISTOTLE trial. 
  • Apixaban: an emerging oral factor Xa inhibitor. 
  • Application of antimicrobial stewardship to optimise management of community acquired pneumonia. 
  • Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90. 
  • Are Prophylactic Postoperative Antibiotics Necessary for Immediate Breast Reconstruction? Results of a Prospective Randomized Clinical Trial. 
  • Aspirated contrast material contributing to respiratory arrest in a pediatric trauma patient. 
  • Aspirin and dry eye? 
  • Assays for measuring rivaroxaban: their suitability and limitations. 
  • Assessment of oral antithrombotic therapy by platelet function testing. 
  • Association Between Gastrointestinal Events and Health Care Resource Utilization Among Patients with Osteoporosis: Analysis of a U.S. Managed Care Population. 
  • Association between oral sildenafil dosing, predicted exposure, and systemic hypotension in hospitalised infants. 
  • Association of Intracerebral Hemorrhage Among Patients Taking Non-Vitamin K Antagonist vs Vitamin K Antagonist Oral Anticoagulants With In-Hospital Mortality. 
  • Association of Preceding Antithrombotic Treatment With Acute Ischemic Stroke Severity and In-Hospital Outcomes Among Patients With Atrial Fibrillation. 
  • Association of methotrexate, rheumatoid arthritis and lymphoma: report of 2 cases and literature review. 
  • Atenolol use and clinical outcomes after thrombolysis for acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA (alteplase) for Occluded Coronary Arteries. 
  • Augmentation of dopaminergic agents for major depressive disorder. 
  • Avoidance of weight gain is important for oral type 2 diabetes treatments in Sweden and Germany: patient preferences. 
  • Azimilide pharmacokinetics and pharmacodynamics upon multiple oral dosing. 
  • BMS-229724 is a tight-binding inhibitor of cytosolic phospholipase A2 that acts at the lipid/water interface and possesses anti-inflammatory activity in skin inflammation models. 
  • Behavioral and neural responses to gustatory stimuli delivered non-contingently through intra-oral cannulas. 
  • Behavioral thermoregulation in the rat following the oral administration of ethanol. 
  • Bidisomide (SC-40230), a new antiarrhythmic agent: initial study of tolerability and pharmacokinetics. 
  • Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. 
  • Biological and pharmacological aspects of perioperative hemorrhagic complications associated with oral platelet-directed antithrombotic agents. Focus on isolated coronary artery bypass grafting and oral irreversible P2Y(12) receptor antagonists. 
  • Blastomycosis. New treatment for an old friend of the Carolinas. 
  • Blending Quality Improvement and Research Methods for Implementation Science, Part II: Analysis of the Quality of Implementation. 
  • Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. 
  • Blood alcohol concentration and psychomotor effects. 
  • Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa). 
  • Breast cancer and estrogen replacement therapy. 
  • Breast cancer oral anti-cancer medication adherence: a systematic review of psychosocial motivators and barriers. 
  • Bupropion SR in the naturalistic treatment of elderly patients with major depression. 
  • COR-ART: A multicenter, randomized, double-blind, placebo-controlled dose-ranging study to evaluate single oral doses of vanoxerine for conversion of recent-onset atrial fibrillation or flutter to normal sinus rhythm. 
  • CT protocols for acute appendicitis: time for change. 
  • Calcitriol for osteitis fibrosa. 
  • Calcium and calmodulin stimulated in vitro phosphorylation of rooster brain tubulin and MAP-2 following a single oral dose of tri-o-cresyl phosphate. 
  • Capecitabine in malignant mesothelioma: a phase II trial by the Cancer and Leukemia Group B (39807). 
  • Cardio-protective effects of carnitine in streptozotocin-induced diabetic rats. 
  • Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats. 
  • Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF. 
  • Challenges in comparing the non-vitamin K antagonist oral anticoagulants for atrial fibrillation-related stroke prevention. 
  • Changes in in vitro brain and spinal cord protein phosphorylation after a single oral administration of tri-o-cresyl phosphate to hens. 
  • Characterization of delayed neurotoxicity in the mouse following chronic oral administration of tri-o-cresyl phosphate. 
  • Choice of vehicle affects pyraclostrobin toxicity in mice. 
  • Cholera toxin acts as a potent adjuvant for the induction of cytotoxic T-lymphocyte responses with non-replicating antigens. 
  • Cholestyramine feeding lowers number of colonic apoptotic cells in rat. 
  • Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 1. 
  • Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 2. 
  • Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial. 
  • Chronic oral amrinone therapy in congestive heart failure: a double-blind placebo-controlled withdrawal study. 
  • Clinical Characteristics, Oral Anticoagulation Patterns, and Outcomes of Medicaid Patients With Atrial Fibrillation: Insights From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF I) Registry. 
  • Clinical Presentation and Management of Hallux Rigidus. 
  • Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis. 
  • Clinical efficacy and immune regulation with peanut oral immunotherapy. 
  • Clinical evaluation of ZD6474, an orally active inhibitor of VEGF and EGF receptor signaling, in patients with solid, malignant tumors. 
  • Clinical outcomes of patients with diabetes and atrial fibrillation treated with apixaban: results from the ARISTOTLE trial. 
  • Clinical outcomes with unfractionated heparin or low-molecular-weight heparin as bridging therapy in patients on long-term oral anticoagulants: the REGIMEN registry. 
  • Clinical significance of perfusion defects by thallium-201 single photon emission tomography following oral dipyridamole early after coronary angioplasty. 
  • Clinical strategies for selecting oral anticoagulants in patients with atrial fibrillation. 
  • Clinical trials treating focal segmental glomerulosclerosis should measure patient quality of life. 
  • Clinical use of the activated partial thromboplastin time and prothrombin time for screening: a review of the literature and current guidelines for testing. 
  • Clinical utility of cytomegalovirus viral load testing for predicting CMV disease in D+/R- solid organ transplant recipients. 
  • Clopidogrel does not induce fibrinolysis in healthy subjects. 
  • Cognitive Function: Is There More to Anticoagulation in Atrial Fibrillation Than Stroke? 
  • Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial. 
  • Collapsing glomerulopathy in 19 patients with systemic lupus erythematosus or lupus-like disease. 
  • Combination chemotherapy in histiocytosis X. 
  • Combination live enteric virus vaccines. 
  • Combined Mechanical and Oral Antibiotic Bowel Preparation Reduces Incisional Surgical Site Infection and Anastomotic Leak Rates After Elective Colorectal Resection: An Analysis of Colectomy-Targeted ACS NSQIP. 
  • Comparative effectiveness of new oral anticoagulants and standard thromboprophylaxis in patients having total hip or knee replacement: a systematic review. 
  • Comparative study of alendronate versus etidronate for the treatment of Paget's disease of bone. 
  • Comparative study of cyclosporine and FK 506 dosage requirements in adult and pediatric orthotopic liver transplant patients. 
  • Comparison of Anticoagulant Therapy for Atrial Fibrillation - Novel Oral Anticoagulants Versus Vitamin K Antagonists. 
  • Comparison of Glucosamine Absorption After Administration of Oral Liquid, Chewable, and Tablet Formulations to Dogs. 
  • Comparison of a single infusion of zoledronic acid with risedronate for Paget's disease. 
  • Comparison of insulin glargine and liraglutide added to oral agents in patients with poorly controlled type 2 diabetes. 
  • Comparison of one-year outcomes following coronary artery stenting in diabetic versus nondiabetic patients (from the Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy [ESPRIT] Trial). 
  • Comparison of pharmacokinetics and safety of voriconazole intravenous-to-oral switch in immunocompromised adolescents and healthy adults. 
  • Comparison of pharmacokinetics and safety of voriconazole intravenous-to-oral switch in immunocompromised children and healthy adults. 
  • Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: a randomised trial. The SYMPHONY Investigators. Sibrafiban versus Aspirin to Yield Maximum Protection from Ischemic Heart Events Post-acute Coronary Syndromes. 
  • Comparison of the efficacy, toxicity, and pharmacokinetics of a uracil/tegafur (UFT) plus oral leucovorin (LV) regimen between Japanese and American patients with advanced colorectal cancer: joint United States and Japan study of UFT/LV. 
  • Comparison of the oral direct thrombin inhibitor ximelagatran with enoxaparin as prophylaxis against venous thromboembolism after total knee replacement: a phase 2 dose-finding study. 
  • Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) trial. 
  • Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies. 
  • Conditioned changes in appetitive and consummatory responses to flavors paired with oral or nutrient reinforcement among adult rats. 
  • Conjunctival pseudotumor caused by herpes simplex virus infection. 
  • Contemporary Trends in Oral Anticoagulant Prescription in Atrial Fibrillation Patients at Low to Moderate Risk of Stroke After Guideline-Recommended Change in Use of the CHADS2 to the CHA2DS2-VASc Score for Thromboembolic Risk Assessment: Analysis From the National Cardiovascular Data Registry's Outpatient Practice Innovation and Clinical Excellence Atrial Fibrillation Registry. 
  • Contraindications to anticoagulation therapy and eligibility for novel anticoagulants in older patients with atrial fibrillation. 
  • Control of plasma uric acid in adults at risk for tumor Lysis syndrome: efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone--results of a multicenter phase III study. 
  • Controversies in oral antiplatelet therapy in patients undergoing aortocoronary bypass surgery. 
  • Conversion to oral controlled-release oxycodone from intravenous opioid analgesic in the postoperative setting. 
  • Cost-effectiveness of botulinum toxin a versus anticholinergic medications for idiopathic urge incontinence. 
  • Cost-effectiveness of new-generation oral cholera vaccines: a multisite analysis. 
  • Cost-effectiveness of oral bisphosphonates for osteoporosis at different ages and levels of life expectancy. 
  • Cost-effectiveness of the oral adsorbent AST-120 versus placebo for chronic kidney disease. 
  • Coumaphos: delayed neurotoxic effect following dermal administration in hens. 
  • Creatine and cyclocreatine attenuate MPTP neurotoxicity. 
  • Current options in oral antiplatelet strategies during percutaneous coronary interventions. 
  • Currently approved and emerging oral therapies in multiple sclerosis: An update for the ophthalmologist. 
  • D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation--observations from the ARISTOTLE trial. 
  • Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis. 
  • Delay of CMV infection in high-risk CMV mismatch lung transplant recipients due to prophylaxis with oral ganciclovir. 
  • Delayed neurotoxicity from continous low-dose oral administration of leptophos to hens. 
  • Delayed neurotoxicity of leptophos and related compounds: differential effects of subchronic oral administration of pure, technical grade and degradation products on the hen. 
  • Design of Randomized, double-blind, Evaluation in secondary Stroke Prevention comparing the EfficaCy and safety of the oral Thrombin inhibitor dabigatran etexilate vs. acetylsalicylic acid in patients with Embolic Stroke of Undetermined Source (RE-SPECT ESUS). 
  • Design of the blockade of the glycoprotein IIb/IIIa receptor to avoid vascular occlusion (BRAVO) trial. 
  • Determination of depleted uranium, pyridostigmine bromide and its metabolite in plasma and urine following combined administration in rats. 
  • Development and utilization of a combined LC-UV and LC-MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin. 
  • Development of an Adult Physiologically Based Pharmacokinetic Model of Solithromycin in Plasma and Epithelial Lining Fluid. 
  • Diabetes and cardiovascular disease during androgen deprivation therapy: observational study of veterans with prostate cancer. 
  • Diagnosis and Treatment of Rosacea Fulminans: A Comprehensive Review. 
  • Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis. 
  • Difluoroethylamines as an amide isostere in inhibitors of cathepsin K. 
  • Direct oral anticoagulants: new drugs and new concepts. 
  • Direct-to-patient expert system and home INR monitoring improves control of oral anticoagulation. 
  • Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer. 
  • Disposition of amiodarone and its proximate metabolite, desethylamiodarone, in the dog for oral administration of single-dose and short-term drug regimens. 
  • Disposition, elimination, and metabolism of tri-o-cresyl phosphate following daily oral administration in Fischer 344 male rats. 
  • Distribution and metabolism of O-ethyl O-4-nitrophenyl phenylphosphonothioate after a single oral dose in one-week old chicks. 
  • Does an oral analgesic protocol improve pain control for patients with cancer? An intergroup study coordinated by the Eastern Cooperative Oncology Group. 
  • Does distance modify the effect of self-testing in oral anticoagulation? 
  • Dose escalation of oral vinorelbine in combination with estramustine in hormone-refractory adenocarcinoma of the prostate. 
  • Dose-finding study of oral idarubicin and cyclophosphamide in first-line treatment of elderly patients with metastatic breast cancer. 
  • Dose-finding, safety, and tolerability study of an oral platelet glycoprotein IIb/IIIa inhibitor, lotrafiban, in patients with coronary or cerebral atherosclerotic disease. 
  • Double-blind randomized study comparing brand-name and generic phenytoin monotherapy. 
  • Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML. 
  • Duvoglustat HCl Increases Systemic and Tissue Exposure of Active Acid α-Glucosidase in Pompe Patients Co-administered with Alglucosidase α. 
  • EDTA chelation therapy alone and in combination with oral high-dose multivitamins and minerals for coronary disease: The factorial group results of the Trial to Assess Chelation Therapy. 
  • Early administration of oropharyngeal colostrum to extremely low birth weight infants. 
  • Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation. 
  • Effect of Diagnosis on Outcomes in the Setting of Enhanced Recovery Protocols. 
  • Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. 
  • Effect of Intravenous Fentanyl on Ticagrelor Absorption and Platelet Inhibition Among Patients Undergoing Percutaneous Coronary Intervention: The PACIFY Randomized Clinical Trial (Platelet Aggregation With Ticagrelor Inhibition and Fentanyl). 
  • Effect of Oral Iron Repletion on Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction and Iron Deficiency: The IRONOUT HF Randomized Clinical Trial. 
  • Effect of Procedure and Coronary Lesion Characteristics on Clinical Outcomes Among Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention: Insights From the PIONEER AF-PCI Trial. 
  • Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes. 
  • Effect of Trichodesma indicum extract on cough reflex induced by sulphur dioxide in mice. 
  • Effect of admission oral diuretic dose on response to continuous versus bolus intravenous diuretics in acute heart failure: an analysis from diuretic optimization strategies in acute heart failure. 
  • Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial. 
  • Effect of apixaban, an oral and direct factor Xa inhibitor, on coagulation activity biomarkers following acute coronary syndrome. 
  • Effect of bismuth salts on systemic and mucosal immune responses to orally administered cholera toxin. 
  • Effect of di(2-ethylhexyl) phthalate on DNA repair and lipid peroxidation in rat hepatocytes and on metabolic cooperation in Chinese hamster V-79 cells. 
  • Effect of dofetilide on survival in patients with supraventricular arrhythmias. 
  • Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial. 
  • Effect of glycemia on plasma incretins and the incretin effect during oral glucose tolerance test. 
  • Effect of high-dose oral multivitamins and minerals in participants not treated with statins in the randomized Trial to Assess Chelation Therapy (TACT). 
  • Effect of hospital use of oral nutritional supplementation on length of stay, hospital cost, and 30-day readmissions among Medicare patients with COPD. 
  • Effect of mirtazapine orally disintegrating tablets on health-related quality of life in elderly depressed patients with comorbid medical disorders: a pilot study. 
  • Effect of oral administration of tri-o-cresyl phosphate on in vitro phosphorylation of membrane and cytosolic proteins from chicken brain. 
  • Effect of oral digoxin in high-risk heart failure patients: a pre-specified subgroup analysis of the DIG trial. 
  • Effect of oral pentoxifylline on cystoid macular edema associated with central retinal vein occlusion. 
  • Effect of propranolol as antiadhesive therapy in sickle cell disease. 
  • Effect of simultaneous didanosine administration on itraconazole absorption in healthy volunteers. 
  • Effect of soy protein ingestion on total and specific immunoglobulin G concentrations in neonatal porcine serum measured by enzyme-linked immunosorbent assay. 
  • Effect of vitamin D supplementation on blood pressure in blacks. 
  • Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial. 
  • Effects of Alcohol on Postoperative Adhesion Formation in Ischemic Myocardium and Pericardium. 
  • Effects of amino acid supplementation on left ventricular remodeling in patients with chronic heart failure with decreased systolic function and diabetes mellitus: rationale and design of a magnetic resonance imaging study. 
  • Effects of an oral growth hormone secretagogue in older adults. 
  • Effects of blackcurrant anthocyanin intake on peripheral muscle circulation during typing work in humans. 
  • Effects of cadmium ingestion and food restriction on energy metabolism and tissue metal concentrations in mallard ducks (Anas platyrhynchos). 
  • Effects of iodine supplementation during pregnancy on child growth and development at school age. 
  • Effects of low-dose morphine on perceived sleep quality in patients with refractory breathlessness: A hypothesis generating study. 
  • Effects of pyridoxal-5'-phosphate (MC-1) in patients undergoing high-risk coronary artery bypass surgery: results of the MEND-CABG randomized study. 
  • Effects of short-term administration of glucocorticoids on bone metabolism in healthy elderly men. 
  • Effects of topical application of free and liposome-encapsulated lactoferrin and lactoperoxidase on oral microbiota and dental caries in rats. 
  • Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants After Cardioversion for Nonvalvular Atrial Fibrillation. 
  • Efficacy and Safety of Rivaroxaban Versus Warfarin in Patients Taking Nondihydropyridine Calcium Channel Blockers for Atrial Fibrillation (from the ROCKET AF Trial). 
  • Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF). 
  • Efficacy and safety of rivaroxaban in patients with diabetes and nonvalvular atrial fibrillation: the Rivaroxaban Once-daily, Oral, Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF Trial). 
  • Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients. 
  • Efficacy and tolerance of high-dose intravenous amiodarone for recurrent, refractory ventricular tachycardia. 
  • Efficacy of oral sucralfate suspension in prevention and treatment of chemotherapy-induced mucositis. 
  • Efficacy of provitamin A carotenoids in reversing vitamin A deficiency induced lesions in brain lipids of chicks. 
  • Efficacy, Safety, and Tolerability of an Extended-Release Orally Disintegrating Methylphenidate Tablet in Children 6-12 Years of Age with Attention-Deficit/Hyperactivity Disorder in the Laboratory Classroom Setting. 
  • Eliglustat maintains long-term clinical stability in patients with Gaucher disease type 1 stabilized on enzyme therapy. 
  • Emergency department contrast practices for abdominal/pelvic computed tomography-a national survey and comparison with the american college of radiology appropriateness criteria(®). 
  • Emerging treatment of acute coronary syndromes with platelet glycoprotein IIB/IIIA inhibitors. 
  • Endophthalmitis following Nd:YAG laser posterior capsulotomy. 
  • Enzalutamide in metastatic prostate cancer before chemotherapy. 
  • Epithelioid hemangioma responsive to oral propranolol. 
  • Epitope maps of the Escherichia coli heat-labile toxin B subunit for development of a synthetic oral vaccine. 
  • Equal antipyretic effectiveness of oral and rectal acetaminophen: a randomized controlled trial [ISRCTN11886401]. 
  • Evaluation of a simpler technique for in-vivo labelling of red blood cells with 99mTc. 
  • Evaluation of anti-pyretic potential of Ficus racemosa bark. 
  • Evaluation of anti-tussive activity of Bergenia ciliata Sternb. rhizome extract in mice. 
  • Evaluation of purgative activity of roots of Rumex nepalensis. 
  • Evaluation of the developmental neuroendocrine and reproductive toxicology of aluminium. 
  • Evidence for diminished B12 absorption after gastric bypass: oral supplementation does not prevent low plasma B12 levels in bypass patients. 
  • Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance. 
  • Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: a randomized, controlled trial. 
  • Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: a randomized, controlled trial. 
  • FEM-PrEP: adherence patterns and factors associated with adherence to a daily oral study product for pre-exposure prophylaxis. 
  • FK 506 rescue therapy for resistant rejection episodes in liver transplant recipients. 
  • Factors Associated With Persistent Increase in Level of Alanine Aminotransferase in Patients With Chronic Hepatitis B Receiving Oral Antiviral Therapy. 
  • Factors associated with non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with new-onset atrial fibrillation: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II). 
  • Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial. 
  • Fish oil feeding modulates leukotriene production in murine lupus nephritis. 
  • Fluvastatin downregulates VEGF-A expression in TNF-α-induced retinal vessel tortuosity. 
  • Four different regimens of farnesyltransferase inhibitor tipifarnib in older, untreated acute myeloid leukemia patients: North American Intergroup Phase II study SWOG S0432. 
  • Fungal prophylaxis in neonates: a review article. 
  • Fungal scleritis after cataract surgery. Successful outcome using itraconazole. 
  • Gallbladder density and iodine concentration in humans during oral cholecystography. A comparison of iopanoic acid and iopronic acid. 
  • Gaps in the evidence base of opioids for refractory breathlessness. A future work plan? 
  • Gastrointestinal Bleeding in Patients With Atrial Fibrillation Treated With Rivaroxaban or Warfarin: ROCKET AF Trial. 
  • Gefitinib (Iressa, ZD1839) and tyrosine kinase inhibitors: the wave of the future in cancer therapy. 
  • Gene expression changes in immune response pathways following oral administration of tetrabromobisphenol A (TBBPA) in female Wistar Han rats. 
  • Genomic correlates of variability in immune response to an oral cholera vaccine. 
  • Glutamine as indispensable nutrient in oncology: experimental and clinical evidence. 
  • Glycoprotein IIb/IIIa receptor antagonists in non-ST elevation acute coronary syndromes and percutaneous revascularisation: a review of trial reports. 
  • Gout management: let's get it right this time. 
  • Guidance for the treatment of deep vein thrombosis and pulmonary embolism. 
  • Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors. 
  • HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge. 
  • Heart failure oral therapies at discharge are associated with better outcome in acute heart failure: a propensity-score matched study. 
  • Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. 
  • Helper Th1 and Th2 cell responses following mucosal or systemic immunization with cholera toxin. 
  • Hepatic lysosomal enzymes in young rats fed retinol. 
  • Hexabromonaphthalene contaminants of polybrominated biphenyls: chemical composition and disposition in the rat. 
  • Higher risk of death and stroke in patients with persistent vs. paroxysmal atrial fibrillation: results from the ROCKET-AF Trial. 
  • Hormonal therapy options for biochemical recurrence of prostate cancer after local therapy. 
  • How treatment priorities influence triptan preferences in clinical practice: perspectives of migraine sufferers, neurologists, and primary care physicians. 
  • Human consumption of methyleugenol and its elimination from serum. 
  • Identifying responders to oral iron supplementation in heart failure with a reduced ejection fraction: a post-hoc analysis of the IRONOUT-HF trial. 
  • Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routes. 
  • Impact of the NICE guideline recommending cessation of antibiotic prophylaxis for prevention of infective endocarditis: before and after study. 
  • Impaired insulin response after oral but not intravenous glucose in heart- and liver-transplant recipients. 
  • Improved Hemoglobin Response with Ferric Carboxymaltose in Patients with Gastrointestinal-Related Iron-Deficiency Anemia Versus Oral Iron. 
  • Improved neurodevelopmental outcomes following long-term high-dose oral acyclovir therapy in infants with central nervous system and disseminated herpes simplex disease. 
  • Improving the prediction of medication compliance: the example of bisphosphonates for osteoporosis. 
  • In-hospital management of type 2 diabetes mellitus. 
  • Increased gastrointestinal ethanol production in obese mice: implications for fatty liver disease pathogenesis. 
  • Induction of hepatic microsomal cytochrome P-450 and inhibition of brain, liver, and plasma esterases by an acute dose of S,S,S-tri-n-butyl phosphorotrithioate (DEF) in the adult hen. 
  • Induction of labor with oral prostaglandin E2. 
  • Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress, following administration of pyridostigmine bromide, DEET (N,N-diethyl-m-toluamide) and permethrin, alone and in combination in rats. 
  • Influence of FK 506 (tacrolimus) on circulating CD4+ T cells expressing CD25 and CD45RA antigens in 19 patients with chronic progressive multiple sclerosis participating in an open label drug safety trial. 
  • Inhibition and recovery of maternal and fetal cholinesterase enzymes following a single oral dose of chlorpyrifos in rats. 
  • Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes. 
  • Inhibitory effect of 2'-fluoro-5-methyl-beta-L-arabinofuranosyl-uracil on duck hepatitis B virus replication. 
  • Initial platelet activity may predict efficacy after chronic oral glycoprotein IIb/IIIa blockade: should we still consider uniform treatment regimens? 
  • Initial testing of the aurora kinase A inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP). 
  • Initial treatment for chronic hepatitis C: current therapies and their optimal dosing and duration. 
  • Inotropic therapy for heart failure: an evidence-based approach. 
  • Insulin analogues: new therapies for type 2 diabetes mellitus. 
  • International Expert Consensus on Switching Platelet P2Y12 Receptor-Inhibiting Therapies. 
  • International trends in clinical characteristics and oral anticoagulation treatment for patients with atrial fibrillation: Results from the GARFIELD-AF, ORBIT-AF I, and ORBIT-AF II registries. 
  • International variation in use of oral anticoagulation among heart failure patients with atrial fibrillation. 
  • Interspecies comparison of pharmacokinetic profile and bioavailability of (+/-)-gossypol in male Fischer-344 rats and male B6C3F mice. 
  • Interventions to promote adherence with oral agents. 
  • Intestinal alkaline phosphatase prevents metabolic syndrome in mice. 
  • Intramuscular testosterone enanthate plus very low dosage oral levonorgestrel suppresses spermatogenesis without causing weight gain in normal young men: a randomized clinical trial. 
  • Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimen. 
  • Intravenous busulfan in pretransplant chemotherapy: bioavailability and patient benefit. 
  • Intravenous versus oral busulfan as part of a busulfan/cyclophosphamide preparative regimen for allogeneic hematopoietic stem cell transplantation: decreased incidence of hepatic venoocclusive disease (HVOD), HVOD-related mortality, and overall 100-day mortality. 
  • Investigating racial disparities in use of NK1 receptor antagonists to prevent chemotherapy-induced nausea and vomiting among women with breast cancer. 
  • Iron deficiency: lessons from anemic mice. 
  • Is bleeding a necessary evil? The inherent risk of antithrombotic pharmacotherapy used for stroke prevention in atrial fibrillation. 
  • Is it safe to use intravenous verapamil to treat a patient who is taking oral verapamil? 
  • Is newer better? Propafenone versus quinidine for conversion of atrial fibrillation. 
  • Isavuconazole for treatment of rare invasive fungal diseases. 
  • Isoflurane alters the kinetics of oral cyclosporine. 
  • Juvenile arthritis and autoimmunity to type II collagen. 
  • Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia. 
  • Lapatinib Plasma and Tumor Concentrations and Effects on HER Receptor Phosphorylation in Tumor. 
  • Laryngeal transplantation in the setting of cancer: a rat model. 
  • Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy. 
  • Late acute, delayed neurotoxic and cholinergic effects of S,S,S-tributyl phosphorotrithioite (Merphos) in hens. 
  • Licorice-associated reversible cerebral vasoconstriction with PRES. 
  • Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination. 
  • Long-term administration of controlled-release oxycodone tablets for the treatment of cancer pain. 
  • Long-term control of bone turnover in Paget's disease with zoledronic acid and risedronate. 
  • Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice. 
  • Low-dose of oral factor Xa inhibitors in patients with a recent acute coronary syndrome: a systematic review and meta-analysis of randomized trials. 
  • Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4. 
  • Maintenance daily oral etoposide versus no further therapy following induction chemotherapy with etoposide plus ifosfamide plus cisplatin in extensive small-cell lung cancer: a Hoosier Oncology Group randomized study. 
  • Mammary gland morphology in Sprague-Dawley rats following treatment with an organochlorine mixture in utero and neonatal genistein. 
  • Management and outcomes of patients presenting with STEMI by use of chronic oral anticoagulation: results from the GRACE registry. 
  • Management of Major Bleeding in Patients With Atrial Fibrillation Treated With Non-Vitamin K Antagonist Oral Anticoagulants Compared With Warfarin in Clinical Practice (from Phase II of the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation [ORBIT-AF II]). 
  • Management of anticoagulation agents in trauma patients. 
  • Management of patients with confirmed and presumed mucous membrane pemphigoid undergoing entropion repair. 
  • Managing new oral anticoagulants in the perioperative and intensive care unit setting. 
  • Managing oral anticoagulant therapy. 
  • Measures of adherence to oral hypoglycemic agents at the primary care clinic level: the role of risk adjustment. 
  • Medical safety in the care of the person with end-stage kidney disease. 
  • Menstrual cycle effects on caffeine elimination in the human female. 
  • Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation. 
  • Methotrexate treatment for sarcoid-associated panuveitis. 
  • Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression. 
  • Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study. 
  • Monitoring oral anticoagulant therapy in patients with lupus anticoagulants. 
  • Monitoring platelet inhibition during chronic oral platelet glycoprotein IIb/IIIa blockade: are we missing something? 
  • Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4. 
  • Multicenter phase II study of a 28-day regimen of orally administered eniluracil and fluorouracil in the treatment of patients with anthracycline- and taxane-resistant advanced breast cancer. 
  • Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: the SPARC trial. 
  • Multiple drug chemotherapy regimen for patients with hormonally-unresponsive carcinoma of the prostate: a preliminary report. 
  • N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents. 
  • Nadolol in the treatment of central serous retinopathy. 
  • Native valve disease in patients with non-valvular atrial fibrillation on warfarin or rivaroxaban. 
  • Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial. 
  • Neuroprotective effects of creatine administration against NMDA and malonate toxicity. 
  • Neurotoxic effects of combined treatment of 2,5-hexanedione and triethyllead chloride. 
  • Neurotoxicity of ethyl methacrylate in rats. 
  • Neurotoxicity resulting from coexposure to pyridostigmine bromide, deet, and permethrin: implications of Gulf War chemical exposures. 
  • New and emerging disease modifying therapies for multiple sclerosis. 
  • New oral anticoagulant-induced bleeding: clinical presentation and management. 
  • New oral anticoagulants in addition to single or dual antiplatelet therapy after an acute coronary syndrome: a systematic review and meta-analysis. 
  • Newer oral anticoagulants should be used as first-line agents to prevent thromboembolism in patients with atrial fibrillation and risk factors for stroke or thromboembolism. 
  • Nicotine increases size and severity of experimental choroidal neovascularization. 
  • Noncentral Nervous System Systemic Embolism in Patients With Atrial Fibrillation: Results From ROCKET AF (Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation). 
  • Novel Oral Anticoagulant Use Among Patients With Atrial Fibrillation Hospitalized With Ischemic Stroke or Transient Ischemic Attack. 
  • Novel oral anticoagulants after acute coronary syndromes. 
  • Novel oral anticoagulants and reversal agents: Considerations for clinical development. 
  • Novel oral anticoagulants: pharmacology, coagulation measures, and considerations for reversal. 
  • Novel tricyclic inhibitors of IKK2: discovery and SAR leading to the identification of 2-methoxy-N-((6-(1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl)pyridin-2-yl)methyl)acetamide (BMS-066). 
  • Obese Children Require Lower Doses of Pantoprazole Than Nonobese Peers to Achieve Equal Systemic Drug Exposures. 
  • Ocular penetration of 5-fluorocytosine. 
  • Off-Label Dosing of Non-Vitamin K Antagonist Oral Anticoagulants and Adverse Outcomes: The ORBIT-AF II Registry. 
  • One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes. 
  • Oral Combination Therapies for Hepatitis C Virus Infection: Successes, Challenges, and Unmet Needs. 
  • Oral Debio1143 (AT406), an antagonist of inhibitor of apoptosis proteins, combined with daunorubicin and cytarabine in patients with poor-risk acute myeloid leukemia--results of a phase I dose-escalation study. 
  • Oral Iron Therapy for Heart Failure With Reduced Ejection Fraction: Design and Rationale for Oral Iron Repletion Effects on Oxygen Uptake in Heart Failure. 
  • Oral agent therapy in the treatment of type 2 diabetes. 
  • Oral antibiotics to prevent postoperative urinary tract infection: a randomized controlled trial. 
  • Oral anticoagulants for stroke prevention in atrial fibrillation: current status, special situations, and unmet needs. 
  • Oral anticoagulation in end-stage renal disease and atrial fibrillation: is it time to just say no to drugs? 
  • Oral anticoagulation management in patients with atrial fibrillation undergoing cardiac implantable electronic device implantation. 
  • Oral antihypertensive trial design and analysis under the pediatric exclusivity provision. 
  • Oral antithrombotic agents for the prevention of stroke in nonvalvular atrial fibrillation: a science advisory for healthcare professionals from the American Heart Association/American Stroke Association. 
  • Oral bisphosphonates reduce the risk of clinical fractures in glucocorticoid-induced osteoporosis in clinical practice. 
  • Oral calcitriol and calcium: efficient therapy for uremic hyperparathyroidism. 
  • Oral dipyridamole increases plasma adenosine levels in human beings. 
  • Oral erythromycin prophylaxis against Streptococcus pyogenes infection in penicillin-allergic military recruits: a randomized clinical trial. 
  • Oral factor Xa inhibitors for the long-term management of ACS. 
  • Oral feeding with pig peripheral lymphocytes decreases the xenogeneic delayed type hypersensitivity reaction in galactosyltransferase knockout mice. 
  • Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia. 
  • Oral glycoprotein IIb/IIIa antagonists: new insights from the SYMPHONY trial. 
  • Oral hydration rotavirus diarrhoea: a double blind comparison of sucrose with glucose electrolyte solution. 
  • Oral immunogenicity of the plant proteinase bromelain. 
  • Oral ketoconazole for prevention of postoperative penile erection: a placebo controlled, randomized, double-blind trial. 
  • Oral methotrexate for recurrent brain tumors in children: a Pediatric Oncology Group study. 
  • Oral misoprostol in preventing postpartum haemorrhage in resource-poor communities: a randomised controlled trial. 
  • Oral nicotine solution for smoking cessation: a pilot tolerability study. 
  • Oral sumatriptan for acute migraine. 
  • Oral transforming growth factor-alpha enhances jejunal mucosal recovery and electrical resistance in piglet rotavirus enteritis. 
  • Oral transmucosal fentanyl citrate as an anaesthetic premedication when dosed to an opioid effect vs total opioid consumption. 
  • Oral typhoid vaccine Ty21a. 
  • Oral vaccine models: multiple delivery systems employing tetanus toxoid. 
  • Oropharyngeal candidiasis in immunocompromised children: a randomized, multicenter study of orally administered fluconazole suspension versus nystatin. The Multicenter Fluconazole Study Group. 
  • Oropharyngeal candidiasis in patients with HIV: suggested guidelines for therapy. 
  • Outcome of Patients Receiving Thrombolytic Therapy While on Rivaroxaban for Nonvalvular Atrial Fibrillation (from Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation). 
  • Outcome of Treatment of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial 2-Year Results. 
  • Outcomes of Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention Receiving an Oral Anticoagulant and Dual Antiplatelet Therapy: A Comparison of Clopidogrel Versus Prasugrel From the TRANSLATE-ACS Study. 
  • Outcomes of discontinuing rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: analysis from the ROCKET AF trial (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation). 
  • Outcomes of temporary interruption of rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: results from the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation (ROCKET AF). 
  • Ovarian reserve diminished by oral cyclophosphamide therapy for granulomatosis with polyangiitis (Wegener's). 
  • Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study. 
  • PA tablets: investigational compounds combining aspirin and omeprazole for cardioprotection. 
  • Parameters for lithium treatment are critical in its enhancement of fracture-healing in rodents. 
  • Paricalcitol versus cinacalcet plus low-dose vitamin D therapy for the treatment of secondary hyperparathyroidism in patients receiving haemodialysis: results of the IMPACT SHPT study. 
  • Paroxetine in the treatment of post-traumatic stress disorder: pooled analysis of placebo-controlled studies. 
  • Participants' Explanations for Nonadherence in the FEM-PrEP Clinical Trial. 
  • Passive immunization of newborn rhesus macaques prevents oral simian immunodeficiency virus infection. 
  • Patterns of Anticoagulation Use and Cardioembolic Risk After Catheter Ablation for Atrial Fibrillation. 
  • Pazopanib in the Treatment of Bilateral Multifocal Renal Oncocytomas: A Case Report. 
  • Pelvic inflammatory disease. 
  • Pentoxifylline increases retinal capillary blood flow velocity in patients with diabetes. 
  • Perioperative bridging therapy with unfractionated heparin or low-molecular-weight heparin in patients with mechanical prosthetic heart valves on long-term oral anticoagulants (from the REGIMEN Registry). 
  • Perioperative management of patients on chronic antithrombotic therapy. 
  • Perioperative management of patients receiving new oral anticoagulants: an international survey. 
  • Periprocedural antithrombotic and bridging therapy: recommendations for standardized reporting in patients with arterial indications for chronic oral anticoagulant therapy. 
  • Periprocedural management of patients receiving a vitamin K antagonist or a direct oral anticoagulant requiring an elective procedure or surgery. 
  • Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients. 
  • Pharmacokinetic and pharmacodynamic effects of elinogrel: results of the platelet function substudy from the intravenous and oral administration of elinogrel to evaluate tolerability and efficacy in nonurgent percutaneous coronary intervention patients (INNOVATE-PCI) trial. 
  • Pharmacokinetic and safety evaluation of SangCya vs Neoral or Sandimmune in stable renal transplant recipients. 
  • Pharmacokinetic comparison of two cyclosporine A formulations, SangCya (Sang-35) and Neoral, in stable adult liver transplant recipients. 
  • Pharmacokinetic effect of AMD070, an Oral CXCR4 antagonist, on CYP3A4 and CYP2D6 substrates midazolam and dextromethorphan in healthy volunteers. 
  • Pharmacokinetic interactions and safety evaluations of coadministered tafenoquine and chloroquine in healthy subjects. 
  • Pharmacokinetic profile of (+/-)-gossypol in male Sprague-Dawley rats following single intravenous and oral and subchronic oral administration. 
  • Pharmacokinetic profile of ganciclovir after its oral administration and from its prodrug, valganciclovir, in solid organ transplant recipients. 
  • Pharmacokinetics and bioequivalence of a combined oral formulation of eniluracil, an inactivator of dihydropyrimidine dehydrogenase, and 5-fluorouracil in patients with advanced solid malignancies. 
  • Pharmacokinetics and clinical impact of all-trans retinoic acid in metastatic breast cancer: a phase II trial. 
  • Pharmacokinetics and metabolism of a single subneurotoxic oral dose of tri-o-cresyl phosphate in hens. 
  • Pharmacokinetics and safety of ebastine in healthy subjects and patients with renal impairment. 
  • Pharmacokinetics of high-dose oral CCNU in bone marrow transplant patients. 
  • Pharmacokinetics of levetiracetam. 
  • Pharmacokinetics of once-daily IV busulfan as part of pretransplantation preparative regimens: a comparison with an every 6-hour dosing schedule. 
  • Pharmacokinetics of posaconazole administered orally or by nasogastric tube in healthy volunteers. 
  • Pharmacological treatment of elderly patients with acute coronary syndromes without persistent ST segment elevation. 
  • Pharmacologically dosed oral glutamine reduces myocardial injury in patients undergoing cardiac surgery: a randomized pilot feasibility trial. 
  • Pharmacology and safety of new oral anticoagulants: the challenge of bleeding persists. 
  • Phase 1 study of TAS-102 administered once daily on a 5-day-per-week schedule in patients with solid tumors. 
  • Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma. 
  • Phase 2 Study of Weekly Paclitaxel Plus Estramustine in Metastatic Hormone-Refractory Prostate Carcinoma: ECOG-ACRIN Cancer Research Group (E1898) Trial. 
  • Phase 2 and 3 clinical trial of oral bexarotene (Targretin capsules) for the treatment of refractory or persistent early-stage cutaneous T-cell lymphoma. 
  • Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group. 
  • Phase I and pharmacokinetic study of erlotinib for solid tumors in patients with hepatic or renal dysfunction: CALGB 60101. 
  • Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301. 
  • Phase I and pharmacological study of oral 9-aminocamptothecin colloidal dispersion (NSC 603071) in patients with advanced solid tumors. 
  • Phase I clinical study of three times a day oral administration of TAS-102 in patients with solid tumors. 
  • Phase I evaluation of zidovudine administered to infants exposed at birth to the human immunodeficiency virus. 
  • Phase I pharmacokinetic studies evaluating single and multiple doses of oral GW572016, a dual EGFR-ErbB2 inhibitor, in healthy subjects. 
  • Phase I study of bevacizumab, everolimus, and panobinostat (LBH-589) in advanced solid tumors. 
  • Phase I study of preoperative oral uracil and tegafur plus leucovorin and radiation therapy in rectal cancer. 
  • Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma. 
  • Phase I study to determine the safety and pharmacokinetics of oral administration of TAS-102 in patients with solid tumors. 
  • Phase I trial of pazopanib in patients with advanced cancer. 
  • Phase II Study of Dasatinib in Previously Treated Patients with Advanced Non-Small Cell Lung Cancer. 
  • Phase II evaluation of oral estramustine, oral etoposide, and intravenous paclitaxel in patients with hormone-sensitive prostate adenocarcinoma. 
  • Phase II open label study of the oral vascular endothelial growth factor-receptor inhibitor PTK787/ZK222584 (vatalanib) in adult patients with refractory or relapsed diffuse large B-cell lymphoma. 
  • Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. 
  • Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme. 
  • Phase II study of oral eniluracil, 5-fluorouracil, and leucovorin in patients with advanced colorectal carcinoma. 
  • Phase II study of the antiangiogenesis agent thalidomide in recurrent or metastatic squamous cell carcinoma of the head and neck. 
  • Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial. 
  • Phase II trial of 5-fluorouracil plus eniluracil in patients with advanced pancreatic cancer: a Southwest Oncology Group study. 
  • Phase II trial of uracil and tegafur plus oral leucovorin: an effective oral regimen in the treatment of metastatic colorectal carcinoma. 
  • Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: results of intergroup protocol 0130. 
  • Phase III, randomized, placebo-controlled study of once-daily oral zibotentan (ZD4054) in patients with non-metastatic castration-resistant prostate cancer. 
  • Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug. 
  • Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma. 
  • Photo quiz. Rocky Mountain Spotted Fever. 
  • Physician practices regarding contraindications to oral anticoagulation in atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. 
  • Physiological role for cholecystokinin in reducing postprandial hyperglycemia in humans. 
  • Pilot study of aprepitant for prevention of post-ERCP pancreatitis in high risk patients: a phase II randomized, double-blind placebo controlled trial. 
  • Plasma concentration time course and pharmacological effects of a standardized oral amiodarone dosing regimen in humans. 
  • Plasma levels of factors II, VII and X and their relationship to the international normalized ratio during chronic warfarin therapy. 
  • Plasma uptake of manganese as affected by oral loads of manganese, calcium, milk, phosphorus, copper, and zinc. 
  • Platelet inhibition with cangrelor in patients undergoing PCI. 
  • Poliovaccine policy--time for a change. 
  • Population-based assessment of adverse events associated with long-term glucocorticoid use. 
  • Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge. 
  • Postnatal pre- and postexposure passive immunization strategies: protection of neonatal macaques against oral simian-human immunodeficiency virus challenge. 
  • Postoperative antibiotic therapy for children with perforated appendicitis: long course of intravenous antibiotics versus early conversion to an oral regimen. 
  • Postoperative oxycodone toxicity in a patient with chronic pain and end-stage renal disease. 
  • Postpartum depression: a randomized trial of sertraline versus nortriptyline. 
  • Prasugrel 5 mg in the very elderly attenuates platelet inhibition but maintains noninferiority to prasugrel 10 mg in nonelderly patients: the GENERATIONS trial, a pharmacodynamic and pharmacokinetic study in stable coronary artery disease patients. 
  • Prevention of intrathecal baclofen withdrawal syndrome: successful use of a temporary intrathecal catheter. 
  • Primary non-adherence to bisphosphonates in an integrated healthcare setting. 
  • Priorities for triptan treatment attributes and the implications for selecting an oral triptan for acute migraine: a study of US primary care physicians (the TRIPSTAR Project). 
  • Procainamide administration during pregnancy. 
  • Programs promoting timely sequential antimicrobial therapy: an American perspective. 
  • Prophylaxis of thromboembolism. 
  • Prophylaxis with oral penicillin in children with sickle cell anemia. A randomized trial. 
  • Propranolol in the treatment of anxiety neurosis. 
  • Prospective trial of pulse oral versus intravenous calcitriol treatment of hyperparathyroidism in ESRD. 
  • Prospective validation of the Bleeding Academic Research Consortium classification in the all-comer PRODIGY trial. 
  • Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies. 
  • Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice. 
  • Pulmonary function in patients with acute coronary syndrome treated with ticagrelor or clopidogrel (from the Platelet Inhibition and Patient Outcomes [PLATO] pulmonary function substudy). 
  • Quality of anticoagulation with warfarin in patients with nonvalvular atrial fibrillation in the community setting. 
  • Quantitative evaluation of alternative mechanisms of blood disposition of di(n-butyl) phthalate and mono(n-butyl) phthalate in rats. 
  • Quantitative thallium-201 single photon emission computed tomography after oral dipyridamole for assessing the presence, anatomic location and severity of coronary artery disease. 
  • Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. 
  • Randomized phase III study of matrix metalloproteinase inhibitor BMS-275291 in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: National Cancer Institute of Canada-Clinical Trials Group Study BR.18. 
  • Randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of a single oral dose of vanoxerine for the conversion of subjects with recent onset atrial fibrillation or flutter to normal sinus rhythm: RESTORE SR. 
  • Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease. 
  • Rationale and clinical evidence for the use of GP IIb/IIIa inhibitors in acute coronary syndromes. 
  • Rationale and design of AXAFA-AFNET 5: an investigator-initiated, randomized, open, blinded outcome assessment, multi-centre trial to comparing continuous apixaban to vitamin K antagonists in patients undergoing atrial fibrillation catheter ablation. 
  • Rationale and design of the Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation (ARTESiA) trial. 
  • Rationale and design of the comParIson Of sacubitril/valsartaN versus Enalapril on Effect on nt-pRo-bnp in patients stabilized from an acute Heart Failure episode (PIONEER-HF) trial. 
  • Rationale and design of the randomized, double-blind trial testing INtraveNous and Oral administration of elinogrel, a selective and reversible P2Y(12)-receptor inhibitor, versus clopidogrel to eVAluate Tolerability and Efficacy in nonurgent Percutaneous Coronary Interventions patients (INNOVATE-PCI). 
  • Rationale for use of an exercise end point and design for the ADVANCE (A Dose evaluation of a Vasopressin ANtagonist in CHF patients undergoing Exercise) trial. 
  • Re: Researchers make slow headway in managing dry mouth. 
  • Redefining medical treatment in the management of unstable angina. 
  • Reduced GABA synthesis in pyridoxine-dependent seizures. 
  • Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. 
  • Regulation of pancreatic endocrine function by cholecystokinin: studies with MK-329, a nonpeptide cholecystokinin receptor antagonist. 
  • Rehydration and maintenance therapy of cholera patients in Jakarta: citrate-based versus bicarbonate-based oral rehydration salt solution. 
  • Reinforcing and subjective effects of methylphenidate in adults with and without attention deficit hyperactivity disorder (ADHD). 
  • Relation of Risk of Stroke in Patients With Atrial Fibrillation to Body Mass Index (from Patients Treated With Rivaroxaban and Warfarin in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation Trial). 
  • Relief of pain and anxiety in pediatric patients in emergency medical systems. 
  • Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts. 
  • Renal hemodynamic and tubular transport effects of nitrendipine. 
  • Response of recurrent medulloblastoma to low-dose oral etoposide. 
  • Results of Prevention of REStenosis with Tranilast and its Outcomes (PRESTO) trial. 
  • Results of a pilot trial comparing prolonged intravenous antibiotics with sequential intravenous/oral antibiotics for children with perforated appendicitis. 
  • Reversal Agents for the New Generation of Oral Anticoagulants: Implications for the Perioperative Physician. 
  • Reversal of selenium deficiency with oral selenium. 
  • Reversing targeted oral anticoagulants. 
  • Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): what is the evidence? 
  • Rhythm control in atrial fibrillation. 
  • Risk of Stroke and Death in Atrial Fibrillation by Type of Anticoagulation: A Propensity-Matched Analysis. 
  • Risks and benefits of anticoagulation in atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. 
  • Risks and benefits of triple oral anti-thrombotic therapies after acute coronary syndromes and percutaneous coronary intervention. 
  • Risks versus benefits of different types of long-acting injectable antipsychotics. 
  • Rituximab versus cyclophosphamide for ANCA-associated vasculitis. 
  • Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. 
  • Rivaroxaban, an oral direct factor Xa inhibitor. 
  • Rivaroxaban-once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation: rationale and design of the ROCKET AF study. 
  • Role of gluten, prednisone, and azathioprine in non-responsive coeliac disease. 
  • Role of lifestyle and oral anti-diabetic agents to prevent type 2 diabetes mellitus and cardiovascular disease. 
  • SPECT/CT localization of oral radioiodine activity: a retrospective study and in-vitro assessment. 
  • Safety and Efficacy of Rivaroxaban in Patients With Cardiac Implantable Electronic Devices: Observations From the ROCKET AF Trial. 
  • Safety and Tolerability of Neladenoson Bialanate, a Novel Oral Partial Adenosine A1 Receptor Agonist, in Patients With Chronic Heart Failure. 
  • Safety and antiviral activity of albinterferon alfa-2b dosed every four weeks in genotype 2/3 chronic hepatitis C patients. 
  • Safety and efficacy of the HIV-1 attachment inhibitor prodrug BMS-663068 in treatment-experienced individuals: 24 week results of AI438011, a phase 2b, randomised controlled trial. 
  • Safety and efficacy of weekly oral oltipraz in chronic smokers. 
  • Safety and pharmacokinetics of 5-chloro-2',3'-dideoxy-3'-fluorouridine (935U83) following oral administration of escalating single doses in human immunodeficiency virus-infected adults. 
  • Safety and tolerance of intermittent intravenous and oral zidovudine therapy in human immunodeficiency virus-infected pediatric patients. Pediatric Zidovudine Phase I Study Group. 
  • Safety of a peanut oral immunotherapy protocol in children with peanut allergy. 
  • Safety of open food challenges in the office setting. 
  • Safety, pharmacokinetics, and pharmacodynamic properties of oral DEBIO1143 (AT-406) in patients with advanced cancer: results of a first-in-man study. 
  • Scalable production of core-shell nanoparticles by flash nanocomplexation to enhance mucosal transport for oral delivery of insulin. 
  • Schedule dependency of 21-day oral versus 3-day intravenous etoposide in combination with intravenous cisplatin in extensive-stage small-cell lung cancer: a randomized phase III study of the Cancer and Leukemia Group B. 
  • Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3. 
  • Selection of Stent Type in Patients With Atrial Fibrillation Presenting With Acute Myocardial Infarction: An Analysis From the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry-Get With the Guidelines. 
  • Self-monitoring of oral anticoagulation: systematic review and meta-analysis of individual patient data. 
  • Sensitization to the cardiovascular but not subject-rated effects of oral cocaine in humans. 
  • Sequential prophylactic oral and empiric once-daily parenteral antibiotics for neutropenia and fever after high-dose chemotherapy and autologous bone marrow support. 
  • Short-term calcitriol administration improves calcium homeostasis in adults with cystic fibrosis. 
  • Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status Trials. 
  • Side effects of oral misoprostol for the prevention of postpartum hemorrhage: results of a community-based randomised controlled trial in rural India. 
  • Single-dose ciraparantag safely and completely reverses anticoagulant effects of edoxaban. 
  • Single-dose pharmacokinetics of sublingual versus oral administration of micronized 17 beta-estradiol. 
  • Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177). 
  • Sofosbuvir and ribavirin for hepatitis C in patients with HIV coinfection. 
  • Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel. 
  • Statins and other cholesterol-lowering medications and the presence of glaucoma. 
  • Steady-state bioavailability of extended-release methylphenidate (MPH-MLR) capsule vs. immediate-release methylphenidate tablets in healthy adult volunteers. 
  • Strategies to reduce bleeding among patients with ischemic heart disease treated with antiplatelet therapies. 
  • Stroke of Known Cause and Underlying Atrial Fibrillation (STROKE-AF) randomized trial: Design and rationale. 
  • Structure-Activity Relationship Studies of Mitogen Activated Protein Kinase Interacting Kinase (MNK) 1 and 2 and BCR-ABL1 Inhibitors Targeting Chronic Myeloid Leukemic Cells. 
  • Structure-activity studies of 2,3,4,4a,5,9b-hexahydroindeno[1,2-c]pyridines as antispermatogenic agents for male contraception. 
  • Structure-function relationships of factor Xa inhibitors: implications for the practicing clinician. 
  • Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation. 
  • Study design and rationale of a comparison of prasugrel and clopidogrel in medically managed patients with unstable angina/non-ST-segment elevation myocardial infarction: the TaRgeted platelet Inhibition to cLarify the Optimal strateGy to medicallY manage Acute Coronary Syndromes (TRILOGY ACS) trial. 
  • Sublingual tacrolimus for immunosuppression in lung transplantation: a potentially important therapeutic option in cystic fibrosis. 
  • Sublingual versus oral immunotherapy for peanut-allergic children: a retrospective comparison. 
  • Substituted thiopyrano[2,3,4-c,d]indoles as potent, selective, and orally active inhibitors of 5-lipoxygenase. Synthesis and biological evaluation of L-691,816. 
  • Sunitinib efficacy against advanced renal cell carcinoma. 
  • Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. 
  • Synthesis and SAR of pyrimidine-based, non-nucleotide P2Y14 receptor antagonists. 
  • Systemic steroids with or without 2% topical minoxidil in the treatment of alopecia areata. 
  • TRIPSTAR: prioritizing oral triptan treatment attributes in migraine management. 
  • Tedizolid for 6 days versus linezolid for 10 days for acute bacterial skin and skin-structure infections (ESTABLISH-2): a randomised, double-blind, phase 3, non-inferiority trial. 
  • Testicular germ-cell apoptosis in stressed rats following combined exposure to pyridostigmine bromide, N,N-diethyl m-toluamide (DEET), and permethrin. 
  • Thallium-201 myocardial imaging in patients with coronary artery disease: comparison of intravenous adenosine and oral dipyridamole. 
  • The Effect of Continued Low Dose Aspirin Therapy in Patients Undergoing Percutaneous Nephrolithotomy. 
  • The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice. 
  • The Use of Oral Beta-Blockers and Clinical Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes: a Long-Term Follow-Up Study. 
  • The Use of Systemic and Topical Fluoroquinolones. 
  • The absorption, distribution, excretion, and metabolism of a single oral dose of O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens. 
  • The combination oral and nutritional treatment of late-onset diabetes mellitus (CONTROL DM) trial results. 
  • The common mucosal immune system: from basic principles to enteric vaccines with relevance for the female reproductive tract. 
  • The discovery of MK-0674, an orally bioavailable cathepsin K inhibitor. 
  • The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor. 
  • The effect of chronic caffeine administration on serum markers of bone mineral metabolism and bone histomorphometry in the rat. 
  • The effect of daily caffeine use on cerebral blood flow: How much caffeine can we tolerate? 
  • The effect of danazol in the treatment of chronic cystic mastitis. 
  • The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients. 
  • The effect of formulation and food consumption on the bioavailability of dovitinib (TKI258) in patients with advanced solid tumors. 
  • The effect of oral 13-cis-retinoic acid on retinal redetachment after surgical repair in eyes with proliferative vitreoretinopathy. 
  • The effect of pentoxifylline on retinal capillary blood flow velocity and whole blood viscosity. 
  • The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies. 
  • The efficacy of isoproterenol inhalation for predicting the response to orally administered theophylline in chronic obstructive pulmonary disease. 
  • The evaluation of drug rechallenge: the casopitant Phase III program. 
  • The failure of orally administered glycoprotein IIb/IIIa inhibitors to prevent recurrent cardiac events. 
  • The impact of docetaxel, estramustine, and low dose hydrocortisone on the quality of life of men with hormone refractory prostate cancer and their partners: a feasibility study. 
  • The in vivo antiviral effect of CL246,738 is mediated by the independent induction of interferon-alpha and interferon-beta. 
  • The new paradigm of hepatitis C therapy: integration of oral therapies into best practices. 
  • The oblique pharyngogram: value in the assessment of dysphagia. 
  • The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration. 
  • The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice. 
  • The periprocedural management of novel oral anticoagulants in patients with nonvalvular atrial fibrillation: rationale and a summary of the available evidence from phase 3 clinical trials. 
  • The pharmacology of novel oral anticoagulants. 
  • The relative neurotoxicities of n-hexane, methyl n-butyl ketone, 2,5-hexanediol, and 2,5-hexanedione following oral or intraperitoneal administration in hens. 
  • The reversible antifertility effect of Piper betle Linn. on Swiss albino male mice. 
  • The role of allopurinol and deferoxamine in preventing pressure ulcers in pigs. 
  • The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine. 
  • The safety and efficacy of apixaban : where do we stand in 2013? 
  • The study of LoSmapimod treatment on inflammation and InfarCtSizE (SOLSTICE): design and rationale. 
  • Therapy with mycophenolate mofetil for refractory acute and chronic GVHD. 
  • To bridge or not to bridge: these are the questions. 
  • To measure or not to measure direct oral anticoagulants before surgery or invasive procedures: comment. 
  • Tocolysis for recurrent preterm labor using a continuous subcutaneous infusion pump. 
  • Tocolytic treatment for preterm contractions with and without cervical changes. 
  • Toddler's behavior and its impacts on exposure to polybrominated diphenyl ethers. 
  • Tolerability of fluoxetine in posttraumatic stress disorder. 
  • Toluene abuse embryopathy: longitudinal neurodevelopmental effects of prenatal exposure to toluene in rats. 
  • Topical and oral administration of the natural water-soluble antioxidant from spinach reduces the multiplicity of papillomas in the Tg.AC mouse model. 
  • Topical versus oral carbonic anhydrase inhibitor therapy for pediatric glaucoma. 
  • Transdermal versus oral estrogen therapy in postmenopausal smokers: hemodynamic and endothelial effects. 
  • Treatment of adult-onset acute macular retinoschisis in enhanced s-cone syndrome with oral acetazolamide. 
  • Treatment of children symptomatic with human immunodeficiency virus infection. 
  • Treatment of diabetes mellitus: implications of the use of oral agents. 
  • Treatment of myelodysplastic syndrome with 2 schedules and doses of oral topotecan: a randomized phase 2 trial by the Cancer and Leukemia Group B (CALGB 19803). 
  • Treatment of palatal myoclonus with sumatriptan. 
  • Treatment of paroxysmal supraventricular tachycardia with oral diltiazem. 
  • Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. 
  • Treatment with oral bromelain decreases colonic inflammation in the IL-10-deficient murine model of inflammatory bowel disease. 
  • Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease. 
  • Tumor prevention by 9-cis-retinoic acid in the N-nitroso-N-methylurea model of mammary carcinogenesis is potentiated by the pineal hormone melatonin. 
  • Ulcerative keratitis in gastrointestinal stromal tumor patients treated with perifosine. 
  • Unravelling the smokers' paradox: cigarette smoking, high-risk coronary artery disease and enhanced clinical efficacy of oral P2Y₁₂ inhibitors. 
  • Updated European Heart Rhythm Association practical guide on the use of non-vitamin-K antagonist anticoagulants in patients with non-valvular atrial fibrillation: Executive summary. 
  • Use of Direct Oral Anticoagulants in Special Populations. 
  • Use of Dual Antiplatelet Therapy and Patient Outcomes in Those Undergoing Percutaneous Coronary Intervention: The ROCKET AF Trial. 
  • Use of fluconazole in a patient with documented malabsorption of ketoconazole. 
  • Use of oral creatine as an ergogenic aid for increased sports performance: perceptions of adolescent athletes. 
  • Use of oral ketoconazole to prevent postoperative erections following penile surgery. 
  • Using a low-sodium, high-potassium salt substitute to reduce blood pressure among Tibetans with high blood pressure: a patient-blinded randomized controlled trial. 
  • Utilization of Standard and Target-Specific Oral Anticoagulants Among Adults in the United Kingdom With Incident Atrial Fibrillation. 
  • Village-based distribution of oral rehydration therapy packets in Bangladesh. 
  • Visual function 5 years after optic neuritis: experience of the Optic Neuritis Treatment Trial. The Optic Neuritis Study Group. 
  • WITHDRAWN: Oral sumatriptan for acute migraine. 
  • We need further studies for the development of "optimized antiplatelet therapy" based on ethnicity. 
  • Weekly oral azithromycin as prophylaxis for agents causing acute respiratory disease. 
  • What is the optimum adjunctive reperfusion strategy for primary percutaneous coronary intervention? 
  • What is the role of combination drug therapy in the treatment of overactive bladder? ICI-RS 2014. 
  • When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH. 
  • Why develop antidotes and reversal agents for non-vitamin K oral anticoagulants? 
  • Ximelagatran versus warfarin for the prevention of venous thromboembolism after total knee arthroplasty. A randomized, double-blind trial. 
  • Zinc and Vitamin Supplementation in an Under-5 Indigenous Population of Guatemala: Influence of Lay Health Promoters in Decreasing Incidence of Diarrhea. 
  • [Computed tomography with thallium-201 and oral dipyridamole in the diagnosis of coronary artery disease]. 
  • [Oral anticoagulation in nonagenarians] 
• 

  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology
  • Allen, Nancy Bates, Professor of Medicine, Medicine, Rheumatology and Immunology
  • Levy, Jerrold Henry, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Middleton, John Paul, Associate Professor of Medicine, Medicine, Nephrology
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. / Guidant Foundation Professor of Cardiology, Medicine, Clinical Pharmacology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Immunology
  • Uronis, Hope Elizabeth, Associate Professor of Medicine, Medicine, Medical Oncology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Professor of Experimental Surgery, in the School of Medicine, Immunology
  • Zafar, Syed Yousuf, Associate Professor of Medicine, Medicine, Medical Oncology
  • Zhong, Xiaoping, Professor of Pediatrics, Immunology