Alleles

• 

  Subject Areas on Research

  • "Any news?" Special issue in honor of Marcus Feldman's 75th birthday. 
  • 1,2-Diacylglycerol choline phosphotransferase catalyzes the final step in the unique Treponema denticola phosphatidylcholine biosynthesis pathway. 
  • A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. 
  • A Case with Purine Nucleoside Phosphorylase Deficiency Suffering from Late-Onset Systemic Lupus Erythematosus and Lymphoma. 
  • A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. 
  • A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population. 
  • A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants. 
  • A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans. 
  • A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. 
  • A PCR-RFLP typing method for adhesion molecule gene polymorphisms and allele frequencies in a normal UK population. 
  • A PCR-based strategy to generate integrative targeting alleles with large regions of homology. 
  • A Recurrent De Novo Variant in NACC1 Causes a Syndrome Characterized by Infantile Epilepsy, Cataracts, and Profound Developmental Delay. 
  • A SIMPLE Pipeline for Mapping Point Mutations. 
  • A candidate taste receptor gene near a sweet taste locus. 
  • A change in the structure of Vbeta chromatin associated with TCR beta allelic exclusion. 
  • A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients. 
  • A common variant associated with prostate cancer in European and African populations. 
  • A common variant near TGFBR3 is associated with primary open angle glaucoma. 
  • A compound nucleotide repeat in the neurofibromatosis (NF1) gene. 
  • A cross-species approach using an in vivo evaluation platform in mice demonstrates that sequence variation in human RABEP2 modulates ischemic stroke outcomes. 
  • A cystic fibrosis transmembrane conductance regulator splice variant with partial penetrance associated with variable cystic fibrosis presentations. 
  • A de novo frame-shift mutation in the tuberin gene. 
  • A deep sequencing approach to estimate Plasmodium falciparum complexity of infection (COI) and explore apical membrane antigen 1 diversity. 
  • A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus. 
  • A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients. 
  • A duplication in chromosome 4q35 is associated with hereditary benign intraepithelial dyskeratosis. 
  • A functional polymorphism in the HTR2C gene associated with stress responses: a validation study. 
  • A functional variant of tandem repeats in human telomerase gene was associated with survival of patients with early stages of non-small cell lung cancer. 
  • A gain-of-function polymorphism controlling complex traits and fitness in nature. 
  • A gene for Hirschsprung disease (megacolon) in the pericentromeric region of human chromosome 10. 
  • A generalized least-squares estimate for the origin of sporophytic self-incompatibility. 
  • A genetic map in the Mimulus guttatus species complex reveals transmission ratio distortion due to heterospecific interactions 
  • A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study. 
  • A genome-wide analysis of putative functional and exonic variation associated with extremely high intelligence 
  • A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. 
  • A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. 
  • A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. 
  • A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease. 
  • A genome-wide scan for common alleles affecting risk for autism. 
  • A genome-wide survey of copy number variations in Han Chinese residing in Taiwan. 
  • A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases. 
  • A germ-line deletion of APOBEC3B does not contribute to subtype-specific childhood acute lymphoblastic leukemia etiology. 
  • A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor. 
  • A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. 
  • A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat. 
  • A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response. 
  • A highly polymorphic cDNA probe in the NF1 gene. 
  • A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan. 
  • A metabolomic signature of the APOE2 allele. 
  • A mitotic recombination system for mouse chromosome 17. 
  • A mouse model of adult-onset anaemia due to erythropoietin deficiency. 
  • A mutation in TNNC1-encoded cardiac troponin C, TNNC1-A31S, predisposes to hypertrophic cardiomyopathy and ventricular fibrillation. 
  • A natural history of melanoma: serial gene expression analysis. 
  • A novel 2-oxoacid-dependent dioxygenase involved in the formation of the goiterogenic 2-hydroxybut-3-enyl glucosinolate and generalist insect resistance in Arabidopsis,. 
  • A novel XPF -357A>C polymorphism predicts risk and recurrence of bladder cancer. 
  • A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. 
  • A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer. 
  • A patient with Ehlers-Danlos syndrome type VI is a compound heterozygote for mutations in the lysyl hydroxylase gene. 
  • A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans. 
  • A promoter polymorphism (-77T>C) of DNA repair gene XRCC1 is associated with risk of lung cancer in relation to tobacco smoking. 
  • A role for MAPK in feedback inhibition of Tcrb recombination. 
  • A simple and improved correction for population stratification in case-control studies. 
  • A simple genetic incompatibility causes hybrid male sterility in mimulus. 
  • A simple procedure for the analysis of single nucleotide polymorphisms facilitates map-based cloning in Arabidopsis. 
  • A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer. 
  • A study in scarlet: MC1R as the main predictor of red hair and exemplar of the flip-flop effect. 
  • A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency. 
  • A tamoxifen inducible knock-in allele for investigation of E2A function. 
  • A three allele TaqI polymorphism at TOP1 gene. 
  • A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells†. 
  • A tripartite interaction among alleles of Notch, Delta, and Enhancer of split during imaginal development of Drosophila melanogaster. 
  • A whole genome approach for discovering the genetic basis of blood group antigens: independent confirmation for P1 and Xg^a . 
  • A widespread chromosomal inversion polymorphism contributes to a major life-history transition, local adaptation, and reproductive isolation. 
  • ALOX5 polymorphism associates with increased leukotriene production and reduced lung function and asthma control in children with poorly controlled asthma. 
  • APOE and AD concordance in twin pairs as predictors of AD in first-degree relatives. 
  • APOE epsilon4 as a predictor of subjective quality of life in a biracial older person community sample. 
  • APOE genotype and hippocampal volume change in geriatric depression. 
  • APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease. 
  • APOE region molecular signatures of Alzheimer's disease across races/ethnicities. 
  • APOE ɛ4 allele and TOMM40-APOC1 variants jointly contribute to survival to older ages. 
  • APOE ϵ4, rated life experiences, and affect among centenarians. 
  • APOE2 allele increased in tardive dyskinesia. 
  • APOL1 genotype-associated morphologic changes among patients with focal segmental glomerulosclerosis. 
  • APOL1 risk alleles among individuals with CKD in Northern Tanzania: A pilot study. 
  • Abnormal osmotic regulation in trpv4-/- mice. 
  • Abscisic acid regulates root elongation through the activities of auxin and ethylene in Arabidopsis thaliana. 
  • Absence of immunodominant anti-Gag p17 (SL9) responses among Gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 allele. 
  • Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation. 
  • Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study. 
  • Accelerated decline in lung function in cigarette smokers is associated with TP53/HDM2 polymorphisms. 
  • Activating mutation in MET oncogene in familial colorectal cancer. 
  • Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway. 
  • Adaptive evolution: evaluating empirical support for theoretical predictions. 
  • Adenosine deaminase deficiency: genotype-phenotype correlations based on expressed activity of 29 mutant alleles. 
  • Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. 
  • Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study. 
  • African-American HLA class II allele and haplotype diversity. 
  • African-American HLA class II allele and haplotype diversity. 
  • Age, gender, and cancer but not neurodegenerative and cardiovascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan. 
  • Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis. 
  • Age-related changes of the 3'APOB-VNTR genotype pool in ageing cohorts. 
  • Aggressive fibromatosis (desmoid tumor) is derived from mesenchymal progenitor cells. 
  • Allele assignment for HLA-A, -B, and -C genes to the Tenth International Histocompatibility Workshop cell lines. 
  • Allele frequency spectra in structured populations: Novel-allele probabilities under the labelled coalescent. 
  • Allele loss on chromosome 1p36 in epithelial ovarian cancers. 
  • Allele-level HLA matching for umbilical cord blood transplantation for non-malignant diseases in children: a retrospective analysis. 
  • Allele-specific analysis reveals exon- and cell-type-specific regulatory effects of Alzheimer's disease-associated genetic variants. 
  • Allele-specific and heritable chromatin signatures in humans. 
  • Allele-specific assay reveals functional variation in the chalcone synthase promoter of Arabidopsis thaliana that is compatible with neutral evolution. 
  • Allele-specific distribution of RNA polymerase II on female X chromosomes. 
  • Allele-specific gene expression in a wild nonhuman primate population. 
  • Allele-specific regulation of TCR beta variable gene segment chromatin structure. 
  • Alleles associated with physical activity levels are estimated to be older than anatomically modern humans. 
  • Alleles of a reelin CGG repeat do not convey liability to autism in a sample from the CPEA network. 
  • Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome. 
  • Allelic and ectopic interactions in recombination-defective yeast strains. 
  • Allelic and ectopic recombination between Ty elements in yeast. 
  • Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis. 
  • Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression. 
  • Allelic differences in the serotonin transporter-linked polymorphic region in geriatric depression. 
  • Allelic diversity and gene genealogy at the self-incompatibility locus in the Solanaceae. 
  • Allelic diversity in the TGFB1 regulatory region: characterization of novel functional single nucleotide polymorphisms. 
  • Allelic exclusion of mouse T cell receptor alpha chains occurs at the time of thymocyte TCR up-regulation. 
  • Allelic exclusion of the T cell receptor alpha-chain: developmental regulation of a post-translational event. 
  • Allelic exclusion of the TCR alpha-chain is an active process requiring TCR-mediated signaling and c-Cbl. 
  • Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat. 
  • Allelotype analysis of uterine leiomyoma: localization of a potential tumor suppressor gene to a 4-cM region of chromosome 7q. 
  • Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects. 
  • Allopurinol hepatotoxicity is associated with human leukocyte antigen Class I alleles. 
  • Alpha₁-antitrypsin deficiency-related alleles Z and S and the risk of Wegener's granulomatosis. 
  • Altered neurotransmission in the lateral amygdala in aged human apoE4 targeted replacement mice. 
  • Alzheimer's disease and apolipoprotein E-4 allele in an Amish population. 
  • Amino acids important in enzyme activity and dimer stability for Drosophila alcohol dehydrogenase. 
  • Amyloid-associated depression and ApoE4 allele: longitudinal follow-up for the development of Alzheimer's disease. 
  • An "almost exhaustive" search-based sequential permutation method for detecting epistasis in disease association studies. 
  • An EcoRI RFLP in the 5' region of the human NF1 gene. 
  • An MYH9 human disease model in flies: site-directed mutagenesis of the Drosophila non-muscle myosin II results in hypomorphic alleles with dominant character. 
  • An allele of HRAS1 3'variable number of tandem repeats is a frailty allele: implication for an evolutionarily-conserved pathway involved in longevity. 
  • An allele-specific hammerhead ribozyme gene therapy for a porcine model of autosomal dominant retinitis pigmentosa. 
  • An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease. 
  • An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome. 
  • An exploration of genetic association tests for disease risk and age at onset. 
  • An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion. 
  • An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa. 
  • An integrated encyclopedia of DNA elements in the human genome. 
  • An integrated map of genetic variation from 1,092 human genomes. 
  • An intronic poly (AT) polymorphism of the DNA repair gene XPC and risk of squamous cell carcinoma of the head and neck: a case-control study. 
  • An investigation of genetic heterogeneity and linkage disequilibrium in 161 families with spinal muscular atrophy. 
  • Analyses of pediatric isolates of Cryptococcus neoformans from South Africa. 
  • Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort. 
  • Analysis of ALDH1A2, CYP26A1, CYP26B1, CRABP1, and CRABP2 in human neural tube defects suggests a possible association with alleles in ALDH1A2. 
  • Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation. 
  • Analysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma. 
  • Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families. 
  • Analysis of a chalcone synthase mutant in Ipomoea purpurea reveals a novel function for flavonoids: amelioration of heat stress. 
  • Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae. 
  • Ancient West African foragers in the context of African population history. 
  • Ancient and recent positive selection transformed opioid cis-regulation in humans. 
  • Angiotensin converting enzyme inhibitors and Alzheimer disease in the presence of the apolipoprotein E4 allele. 
  • ApoE genotype and survival from intracerebral haemorrhage. 
  • ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy. 
  • Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression. 
  • Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. 
  • Apolipoprotein E alleles and sensorineural hearing loss. 
  • Apolipoprotein E and Alzheimer disease. 
  • Apolipoprotein E and Alzheimer's disease. 
  • Apolipoprotein E and Alzheimer's disease: signal transduction mechanisms. 
  • Apolipoprotein E and brain injury: implications for children. 
  • Apolipoprotein E and neuromuscular disease: a critical review of the literature. 
  • Apolipoprotein E controls the risk and age at onset of Parkinson disease. 
  • Apolipoprotein E epsilon 4 allele and hippocampal volume in twins with normal cognition. 
  • Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. 
  • Apolipoprotein E epsilon 4. 
  • Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease. 
  • Apolipoprotein E gene polymorphisms and retinal vascular signs: the atherosclerosis risk in communities (ARIC) study. 
  • Apolipoprotein E genotype and subcortical vascular lesions in older depressed patients and control subjects. 
  • Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease. 
  • Apolipoprotein E in Creutzfeldt-Jacob disease. 
  • Apolipoprotein E in Creutzfeldt-Jakob disease. 
  • Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice. 
  • Apolipoprotein E polymorphism and the risk of acute nephropathy after cardiac surgery. 
  • Apolipoprotein E polymorphisms and age at first coronary artery bypass graft. 
  • Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease. 
  • Apolipoprotein E-epsilon 4 frequency in geriatric depression. 
  • Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. 
  • Apolipoprotein e gene and age-related maculopathy in older individuals: the cardiovascular health study. 
  • Apolipoprotein epsilon 4 genotype is associated with less improvement in cognitive function five years after cardiac surgery: a retrospective cohort study. 
  • Approximating selective sweeps. 
  • Architecture of the human regulatory network derived from ENCODE data. 
  • Are Lethal Alleles Too Abundant in Humans? 
  • Are mutations in the cystic fibrosis gene important in chronic pancreatitis? 
  • Aspirin resistance and a single gene. 
  • Assessing genetic association with human survival at multi-allelic loci. 
  • Assessing population structure and host specialization in lichenized cyanobacteria. 
  • Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. 
  • Assessment of small in-frame indels and C-terminal nonsense variants of BRCA1 using a validated functional assay. 
  • Assignment of the zeta-crystallin gene (CRYZ) to human chromosome 1p22-p31 and identification of restriction fragment length polymorphisms. 
  • Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. 
  • Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease. 
  • Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. 
  • Association between bleomycin hydrolase and Alzheimer's disease in caucasians. 
  • Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. 
  • Association between genetic variation at the porphobilinogen deaminase gene and schizophrenia. 
  • Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. 
  • Association between p53 Arg72Pro polymorphism and colorectal cancer risk: a meta-analysis. 
  • Association of BRCA1 functional single nucleotide polymorphisms with risk of differentiated thyroid carcinoma. 
  • Association of GATA3 Polymorphisms With Minimal Residual Disease and Relapse Risk in Childhood Acute Lymphoblastic Leukemia. 
  • Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 
  • Association of Long-term Ambient Black Carbon Exposure and Oxidative Stress Allelic Variants With Intraocular Pressure in Older Men. 
  • Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. 
  • Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. 
  • Association of circadian genes with diurnal blood pressure changes and non-dipper essential hypertension: a genetic association with young-onset hypertension. 
  • Association of estrogen receptor β polymorphisms with posterior tibial tendon dysfunction. 
  • Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery. 
  • Association of genetic variants in the HDL receptor, SR-B1, with abnormal lipids in women with coronary artery disease. 
  • Association of genetic variants of FBXO32 and FOXO6 in the FOXO pathway with breast cancer risk. 
  • Association of genetic variation in IKZF1, ARID5B, and CEBPE and surrogates for early-life infections with the risk of acute lymphoblastic leukemia in Hispanic children. 
  • Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. 
  • Association of hsp70 polymorphisms with risk of noise-induced hearing loss in Chinese automobile workers. 
  • Association of increased spontaneous mutation rates with high levels of transcription in yeast. 
  • Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. 
  • Association of maternal IL-1 receptor antagonist intron 2 gene polymorphism and preterm birth. 
  • Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. 
  • Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis. 
  • Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery. 
  • Association of the CCR5 gene with juvenile idiopathic arthritis. 
  • Association of the HLA-DQA1*0501 allele in multiple racial groups with juvenile dermatomyositis. 
  • Association of the apolipoprotein E gene with age-related macular degeneration: possible effect modification by family history, age, and gender. 
  • Association of the congenital neuromuscular form of glycogen storage disease type IV with a large deletion and recurrent frameshift mutation. 
  • Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma. 
  • Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk. 
  • Association study of Parkin gene polymorphisms with idiopathic Parkinson disease. 
  • Association with HLA-DRβ1 position 37 distinguishes juvenile dermatomyositis from adult-onset myositis. 
  • Associations Between Catecholaminergic and Serotonergic Genes and Persistent Arm Pain Severity Following Breast Cancer Surgery. 
  • Associations between HLA class I alleles and the prevalence of nasopharyngeal carcinoma (NPC) among Tunisians. 
  • Associations between genome-wide Native American ancestry, known risk alleles and B-cell ALL risk in Hispanic children. 
  • Associations between serotonin transporter gene promoter region (5-HTTLPR) polymorphism and gaze bias for emotional information. 
  • Associations between smoking behavior-related alleles and the risk of melanoma. 
  • Associations of a regulatory polymorphism of monoamine oxidase-A gene promoter (MAOA-uVNTR) with symptoms of depression and sleep quality. 
  • Associations of candidate genes to age-related macular degeneration among racial/ethnic groups in the multi-ethnic study of atherosclerosis. 
  • Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking. 
  • Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers. 
  • Atypical chromosome 22q11.2 deletions are complex rearrangements and have different mechanistic origins. 
  • Aurora-A kinase is essential for bipolar spindle formation and early development. 
  • BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis. 
  • BRCA1 mutations in primary breast and ovarian carcinomas. 
  • Balancing selection and trans-specific polymorphisms. 
  • Bayesian estimation of genetic regulatory effects in high-throughput reporter assays. 
  • Beat frequency is bimodally distributed in spermatozoa from T/t12 mice. 
  • Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium. 
  • Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation. 
  • Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context. 
  • Beta2-adrenergic receptor genotype affects the renin-angiotensin-aldosterone system response to the Dietary Approaches to Stop Hypertension (DASH) dietary pattern. 
  • Bethlem myopathy is not allelic to limb-girdle muscular dystrophy type 1A. 
  • Bi-allelic KARS1 pathogenic variants affecting functions of cytosolic and mitochondrial isoforms are associated with a progressive and multisystem disease. 
  • Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. 
  • Bi-allelic variants in the ER quality-control mannosidase gene EDEM3 cause a congenital disorder of glycosylation. 
  • Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder. 
  • Biallelic SQSTM1 mutations in early-onset, variably progressive neurodegeneration. 
  • Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers. 
  • Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy. 
  • Biallelic mutations in FDXR cause neurodegeneration associated with inflammation. 
  • Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis. 
  • Biallelic variants in AGMO with diminished enzyme activity are associated with a neurodevelopmental disorder. 
  • Biallelic variants in PPP1R13L cause paediatric dilated cardiomyopathy. 
  • Birth Cohort, Age, and Sex Strongly Modulate Effects of Lipid Risk Alleles Identified in Genome-Wide Association Studies. 
  • Bisulfite sequencing of cloned alleles. 
  • Brief Report: HLA-DRB1, DQA1, and DQB1 in Juvenile-Onset Systemic Sclerosis. 
  • CASP7 variants modify susceptibility to cervical cancer in Chinese women. 
  • CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States. 
  • CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy. 
  • COMT Val(158) Met genotype is associated with reward learning: a replication study and meta-analysis. 
  • COMT Val158Met Polymorphism, Cardiometabolic Risk, and Nadir CD4 Synergistically Increase Risk of Neurocognitive Impairment in Men Living With HIV. 
  • CRHBP polymorphisms predict chronic pain development following motor vehicle collision. 
  • CTLA-4 gene polymorphisms and systemic lupus erythematosus in a population-based study of whites and African-Americans in the southeastern United States. 
  • CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival. 
  • CYP3A4 and CYP3A5 polymorphisms and blood pressure response to amlodipine among African-American men and women with early hypertensive renal disease. 
  • Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. 
  • Cancer and Leukemia Group B 90206: A randomized phase III trial of interferon-alpha or interferon-alpha plus anti-vascular endothelial growth factor antibody (bevacizumab) in metastatic renal cell carcinoma. 
  • Cancer-associated isocitrate dehydrogenase mutations induce mitochondrial DNA instability. 
  • Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. 
  • Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk. 
  • Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans. 
  • Cell non-autonomous requirement of p75 in the development of geniculate oral sensory neurons. 
  • Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair. 
  • Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation. 
  • Central nervous system serotonin and clustering of hostility, psychosocial, metabolic, and cardiovascular endophenotypes in men. 
  • Central nervous system serotonin function and cardiovascular responses to stress. 
  • Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. 
  • Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants. 
  • Childhood socioeconomic status and serotonin transporter gene polymorphism enhance cardiovascular reactivity to mental stress. 
  • Choline Acetyltransferase Mutations Causing Congenital Myasthenic Syndrome: Molecular Findings and Genotype-Phenotype Correlations. 
  • Chromatin architecture reorganization during stem cell differentiation. 
  • Chromosomal rearrangements accompanying yeast mating-type switching: evidence for a gene-conversion model. 
  • Chromosome 8q24 markers: risk of early-onset and familial prostate cancer. 
  • Chromosome breakage in Drosophila melanogaster induced by a monofunctional alkylating agent (EMS). 
  • Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair. 
  • Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples. 
  • Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice. 
  • Clinical Pharmacogenetics Implementation Consortium guidelines for human leukocyte antigen-B genotype and allopurinol dosing. 
  • Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity. 
  • Clinical application of apolipoprotein E genotyping to Alzheimer's disease. 
  • Clinical hepatitis after transplantation of hepatitis C virus-positive kidneys: HLA-DR3 as a risk factor for the development of posttransplant hepatitis. 
  • Clinical heterogeneity of mitochondrial NAD kinase deficiency caused by a NADK2 start loss variant. 
  • Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • Clinical, 18F-dopa PET, and genetic analysis of an ethnic Chinese kindred with early-onset parkinsonism and parkin gene mutations. 
  • Clonal origin of epithelial ovarian carcinoma: analysis by loss of heterozygosity, p53 mutation, and X-chromosome inactivation. 
  • Cloning, characterization, and genetic mapping of the rat type 2 angiotensin II receptor gene. 
  • Clustered charged amino acids of human adenosine deaminase comprise a functional epitope for binding the adenosine deaminase complexing protein CD26/dipeptidyl peptidase IV. 
  • Coevolution of self-fertilization and inbreeding depression. I. Mutation-selection balance at one and two loci. 
  • Coevolution of self-fertilization and inbreeding depression. II. Symmetric overdominance in viability. 
  • Coevolution of the major histocompatibility complex and the t-complex in the mouse. II. Modification of response to sharing of histocompatibility antigens. 
  • Cognitive correlates of a functional COMT polymorphism in children with 22q11.2 deletion syndrome. 
  • Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene. 
  • Combined effects of the p53 and p73 polymorphisms on lung cancer risk. 
  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk. 
  • Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer. 
  • Common genetic variation and the control of HIV-1 in humans. 
  • Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. 
  • Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese. 
  • Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome. 
  • Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. 
  • Comparative analyses of clinical and environmental populations of Cryptococcus neoformans in Botswana. 
  • Comparisons of mixed leukocyte reactions with skin graft survival in families genotyped for HL-A. 
  • Complement factor H variant increases the risk of age-related macular degeneration. 
  • Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. 
  • Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy? 
  • Complex relationship between Parkin mutations and Parkinson disease. 
  • Complex selection on a regulator of social cognition: Evidence of balancing selection, regulatory interactions and population differentiation in the prairie vole Avpr1a locus. 
  • Complexity of the msp2 locus and the severity of childhood malaria, in south-western Nigeria. 
  • Comprehensive analysis of chromosome 1p deletions in neuroblastoma. 
  • Comprehensive biomarker and genomic analysis identifies p53 status as the major determinant of response to MDM2 inhibitors in chronic lymphocytic leukemia. 
  • Concatenation and concordance in the reconstruction of mouse lemur phylogeny: an empirical demonstration of the effect of allele sampling in phylogenetics. 
  • Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model. 
  • Confirmation of linkage of oculopharyngeal muscular dystrophy to chromosome 14q11.2-q13. 
  • Connecting genetic risk to disease end points through the human blood plasma proteome. 
  • Consistent production of transgenic chickens using replication-deficient retroviral vectors and high-throughput screening procedures. 
  • Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys. 
  • Control elements within the PWS/AS imprinting box and their function in the imprinting process. 
  • Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica. 
  • Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. 
  • Convergent evolution of linked mating-type loci in basidiomycete fungi. 
  • Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples. 
  • Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae. 
  • Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci. 
  • Cordon-bleu is a conserved gene involved in neural tube formation. 
  • Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers. 
  • Cost-effectiveness of HLA-B*1502 genotyping in adult patients with newly diagnosed epilepsy in Singapore. 
  • Cross-species amplification, non-invasive genotyping, and non-Mendelian inheritance of human STRPs in Savannah baboons. 
  • Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease. 
  • Cyclic AMP-dependent protein kinase catalytic subunits have divergent roles in virulence factor production in two varieties of the fungal pathogen Cryptococcus neoformans. 
  • Cycloheximide-resistant temperature-sensitive lethal mutations of Saccharomyces cerevisiae. 
  • Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations. 
  • Cystic fibrosis in Jews: frequency and mutation distribution. 
  • Cytokine polymorphic analyses indicate ethnic differences in the allelic distribution of interleukin-2 and interleukin-6. 
  • D2 dopamine receptor A1 allele in Alzheimer disease and aging. 
  • DNA mismatch repair network gene polymorphism as a susceptibility factor for pancreatic cancer. 
  • DNA repair gene XPC genotypes/haplotypes and risk of lung cancer in a Chinese population. 
  • DNA sequence analysis and restriction fragment length polymorphism (RFLP) typing of the HLA-DQw2 alleles associated with dermatitis herpetiformis. 
  • De Novo Mutations in SLC1A2 and CACNA1A Are Important Causes of Epileptic Encephalopathies. 
  • De novo variants in TCF7L2 are associated with a syndromic neurodevelopmental disorder. 
  • De novo variants in the alternative exon 5 of SCN8A cause epileptic encephalopathy. 
  • Decrease in the lgl tumor suppressor dose in Drosophila increases survival and longevity in stress conditions. 
  • Decreased PPAR gamma expression compromises perigonadal-specific fat deposition and insulin sensitivity. 
  • Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment. 
  • Decreased tumorigenesis in mice with a Kras point mutation at C118. 
  • Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk. 
  • Deleterious mutations and genetic variation for flower size in Mimulus guttatus. 
  • Deletion of cysteine 369 in lysyl hydroxylase 1 eliminates enzyme activity and causes Ehlers-Danlos syndrome type VI. 
  • Delineating the requirements for spontaneous DNA damage resistance pathways in genome maintenance and viability in Saccharomyces cerevisiae. 
  • Della proteins and gibberellin-regulated seed germination and floral development in Arabidopsis. 
  • Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. 
  • Dentatorubral-pallidoluysian atrophy and Haw River syndrome. 
  • Depression, Stressful Life Events, and the Impact of Variation in the Serotonin Transporter: Findings from the National Longitudinal Study of Adolescent to Adult Health (Add Health). 
  • Depressive symptoms moderate the influence of the apolipoproteine epsilon4 allele on cognitive decline in a sample of community dwelling older adults. 
  • Detailed analysis of allelic variation in the ABCA4 gene in age-related maculopathy. 
  • Detailed molecular analysis of 1p36 in neuroblastoma. 
  • Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor. 
  • Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment. 
  • Determinants of effective population size for loci with different modes of inheritance. 
  • Developmental mediation of genetic variation in response to the Fast Track prevention program. 
  • Differences in Methadone Metabolism by CYP2B6 Variants. 
  • Differences in apolipoprotein E3/3 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. 
  • Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation. 
  • Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior. 
  • Diminished class II-associated Ii peptide binding to the juvenile dermatomyositis HLA-DQ alpha 1*0501/DQ beta 1*0301 molecule. 
  • Dinucleotide repeat polymorphism at the human erythropoietin receptor locus (EPOR) at 19p13. 
  • Dinucleotide repeat polymorphisms at the SCN4A locus suggest allelic heterogeneity of hyperkalemic periodic paralysis and paramyotonia congenita. 
  • Direct allelic variation scanning of the yeast genome. 
  • Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo. 
  • Discovery and fine mapping of serum protein loci through transethnic meta-analysis. 
  • Discovery and functional annotation of SIX6 variants in primary open-angle glaucoma. 
  • Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. 
  • Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele. 
  • Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae. 
  • Dissecting the architecture of a quantitative trait locus in yeast. 
  • Dissecting the gene dose-effects of the APOE ε4 and ε2 alleles on hippocampal volumes in aging and Alzheimer's disease. 
  • Dissection of genetic pathways in C. elegans. 
  • Distal nephron renal tumors: microsatellite allelotype. 
  • Distinct regions of allelic loss on 13q in prostate cancer. 
  • Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program. 
  • Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis? 
  • Dominance of wild-type p53-mediated transcriptional activation in breast epithelial cells. 
  • Double mutant fibrillin-1 (FBN1) allele in a patient with neonatal Marfan syndrome. 
  • Dr(a-) polymorphism of decay accelerating factor. Biochemical, functional, and molecular characterization and production of allele-specific transfectants. 
  • Drawing inferences about the coancestry coefficient. 
  • Drosophila betaHeavy-spectrin is essential for development and contributes to specific cell fates in the eye. 
  • Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia. 
  • E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression. 
  • EFFECT OF THE APOE ε4 ALLELE AND COMBAT EXPOSURE ON PTSD AMONG IRAQ/AFGHANISTAN-ERA VETERANS. 
  • EMK: a novel program for family-based allelic and genotypic association tests on quantitative traits. 
  • ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: a systemic review and meta-analysis. 
  • Early onset prostate cancer has a significant genetic component. 
  • Effect of CYP2C19*2 and *3 loss-of-function alleles on platelet reactivity and adverse clinical events in East Asian acute myocardial infarction survivors treated with clopidogrel and aspirin. 
  • Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system. 
  • Effect of apolipoprotein E genotype on in-hospital mortality following intracerebral haemorrhage. 
  • Effect of insulin-like growth factor gene polymorphisms alone or in interaction with diabetes on the risk of pancreatic cancer. 
  • Effects of 5HTTLPR on cardiovascular response to an emotional stressor. 
  • Effects of HTR1A C(-1019)G on amygdala reactivity and trait anxiety. 
  • Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. 
  • Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival. 
  • Effects of sequence variation on differential allelic transcription factor occupancy and gene expression. 
  • Effects of source of DNA on genotyping success rates and allele percentages in the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS). 
  • Efficacy of clopidogrel for stroke depends on CYP2C19 genotype and risk profile. 
  • Ehlers-Danlos syndrome type VI results from a nonsense mutation and a splice site-mediated exon-skipping mutation in the lysyl hydroxylase gene. 
  • Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency. 
  • Endoglin deficiency impairs stroke recovery. 
  • Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes. 
  • Environment-dependent inbreeding depression: its ecological and evolutionary significance. 
  • Epidemiology of 21-hydroxylase deficiency in Singapore. 
  • Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia. 
  • Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. 
  • Establishment and characterization of conditionally immortalized cells from the mouse urogenital ridge. 
  • Ethnicity greatly influences cytokine gene polymorphism distribution. 
  • Evaluating the precision of EBF1 SNP x stress interaction association: sex, race, and age differences in a big harmonized data set of 28,026 participants. 
  • Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation. 
  • Evaluation of genotype-specific survival using joint analysis of genetic and non-genetic subsamples of longitudinal data. 
  • Evidence That an Unconventional Actin Can Provide Essential F-Actin Function and That a Surveillance System Monitors F-Actin Integrity in Chlamydomonas. 
  • Evidence for a one-allele assortative mating locus. 
  • Evidence for a striking increase in acetylcholinesterase activity in cultured human fibroblasts which are trisomic for chromosome two. 
  • Evidence for linkage of HLA loci in juvenile idiopathic oligoarthritis: independent effects of HLA-A and HLA-DRB1. 
  • Evidence for selection at multiple allozyme loci across a mussel hybrid zone. 
  • Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa. 
  • Evolution of the bipolar mating system of the mushroom Coprinellus disseminatus from its tetrapolar ancestors involves loss of mating-type-specific pheromone receptor function. 
  • Evolutionary dynamics of dual-specificity self-incompatibility alleles. 
  • Evolutionary dynamics of self-incompatibility alleles in Brassica. 
  • Evolutionary effects of contagious and familial transmission. 
  • Evolutionary history of microsatellites in the obscura group of Drosophila. 
  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study. 
  • Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. 
  • Expanding allelic and phenotypic spectrum of ZC4H2-related disorder: A novel hypomorphic variant and high prevalence of tethered cord. 
  • Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain. 
  • Expansion of the human mu-opioid receptor gene architecture: novel functional variants. 
  • Exploring the genetic basis of chronic periodontitis: a genome-wide association study. 
  • Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin. 
  • Expression and trans-specific polymorphism of self-incompatibility RNases in coffea (Rubiaceae). 
  • Expression inheritance and constraints on cis- and trans-regulatory mutations underlying lotus color variation. 
  • Expression of the gene defect in X-linked agammaglobulinemia. 
  • Extensive haplotype diversity in African American mothers and their cord blood units. 
  • FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations. 
  • FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity. 
  • FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. 
  • Failure to replicate two mate preference QTLs across multiple strains of Drosophila pseudoobscura. 
  • Familial transmission of the FMR1 CGG repeat. 
  • Fast and robust association tests for untyped SNPs in case-control studies. 
  • Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1. 
  • Fine localization of the CMT4A locus using a PAC contig and haplotype analysis. 
  • Fine mapping of the Pc locus of Sorghum bicolor, a gene controlling the reaction to a fungal pathogen and its host-selective toxin. 
  • Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity. 
  • Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases. 
  • Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans. 
  • Floral-color polymorphism in Ipomoea purpurea: biased inheritance of the dark allele is not a general explanation for its maintenance. 
  • Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups. 
  • Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. 
  • Fragile X males with unmethylated, full mutation trinucleotide repeat expansions have elevated levels of FMR1 messenger RNA. 
  • Frameshift mutagenesis: the roles of primer-template misalignment and the nonhomologous end-joining pathway in Saccharomyces cerevisiae. 
  • Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer. 
  • Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. 
  • Full-length nucleotide sequence of ERMAP alleles encoding Scianna (SC) antigens. 
  • Functional analysis of SPINDLY in gibberellin signaling in Arabidopsis. 
  • Functional analysis of Wingless reveals a link between intercellular ligand transport and dorsal-cell-specific signaling. 
  • Functional epialleles at an endogenous human centromere. 
  • Functional genetic variants of XRCC4 and ERCC1 predict survival of gastric cancer patients treated with chemotherapy by regulating the gene expression. 
  • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. 
  • Functional polymorphisms in the promoter regions of the FAS and FAS ligand genes and risk of bladder cancer in south China: a case-control analysis. 
  • Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese. 
  • Functional polymorphisms of matrix metalloproteinase-9 are associated with risk of occurrence and metastasis of lung cancer. 
  • Functional replacement of the mouse E2A gene with a human HEB cDNA. 
  • Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB. 
  • Functions of the myosin ATP and actin binding sites are required for C. elegans thick filament assembly. 
  • Further evidence that transposition of Tn5 in Escherichia coli is strongly enhanced by constitutively activated RecA proteins. 
  • Further exclusion of FSHD1B from the telomeric region of 10q. 
  • G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans. 
  • GAA variants and phenotypes among 1,079 patients with Pompe disease: Data from the Pompe Registry. 
  • GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. 
  • Gastrostomy in oropharyngeal cancer patients with ERCC4 (XPF) germline variants. 
  • Gene conversion in the absence of reciprocal recombination. 
  • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. 
  • Gene duplication in the diversification of secondary metabolism: tandem 2-oxoglutarate-dependent dioxygenases control glucosinolate biosynthesis in Arabidopsis. 
  • Gene expression divergence and the origin of hybrid dysfunctions. 
  • Gene segment selection in V(D)J recombination: accessibility and beyond. 
  • Gene targeting of a CFTR allele in HT29 human epithelial cells. 
  • Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations. 
  • Gene-environment interplay and psychopathology: multiple varieties but real effects. 
  • Genealogical structure among alleles regulating self-incompatibility in natural populations of flowering plants. 
  • Genealogy-dependent variation in viability among self-incompatibility genotypes. 
  • Generation of a Magoh conditional allele in mice. 
  • Generation of a loxP flanked bmp4loxP-lacZ allele marked by conditional lacZ expression. 
  • Genes and longevity: lessons from studies of centenarians. 
  • Genetic Basis of Health Disparity in Childhood Nephrotic Syndrome. 
  • Genetic Dissection of Sexual Reproduction in a Primary Homothallic Basidiomycete. 
  • Genetic Identification of Two Novel Loci Associated with Steroid-Sensitive Nephrotic Syndrome. 
  • Genetic Polymorphisms of CFH and ARMS2 Do Not Predict Response to Antioxidants and Zinc in Patients with Age-Related Macular Degeneration: Independent Statistical Evaluations of Data from the Age-Related Eye Disease Study. 
  • Genetic Variants in WNT2B and BTRC Predict Melanoma Survival. 
  • Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis. 
  • Genetic analysis of multiplex rheumatoid arthritis families. 
  • Genetic and biochemical characterization of mutants at an RNA polymerase II locus in D. melanogaster. 
  • Genetic association between endothelial nitric oxide synthase and Alzheimer disease. 
  • Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. 
  • Genetic basis for p53 overexpression in human breast cancer. 
  • Genetic basis of glycogen storage disease type 1a: prevalent mutations at the glucose-6-phosphatase locus. 
  • Genetic changes in human adrenocortical carcinomas. 
  • Genetic counseling for fragile x syndrome: updated recommendations of the national society of genetic counselors. 
  • Genetic determinants of serum testosterone concentrations in men. 
  • Genetic diversity among Mycobacterium avium complex strains recovered from children with and without human immunodeficiency virus infection. 
  • Genetic diversity in the Mycobacterium tuberculosis complex based on variable numbers of tandem DNA repeats. 
  • Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis. 
  • Genetic epidemiology of the susceptibility to leprosy. 
  • Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. 
  • Genetic evidence reveals temporal change in hybridization patterns in a wild baboon population. 
  • Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break. 
  • Genetic factors influencing prostate cancer risk in Norwegian men. 
  • Genetic heterogeneity in MCAD deficiency: frequency of K329E allele and identification of three additional mutant alleles. 
  • Genetic insights into biological mechanisms governing human ovarian ageing. 
  • Genetic nature of individual frailty: comparison of two approaches. 
  • Genetic polymorphism at the glutathione S-transferase (GST) P1 locus is a breast cancer risk modifier. 
  • Genetic polymorphisms and the risk of stroke after cardiac surgery. 
  • Genetic polymorphisms associated with priapism in sickle cell disease. 
  • Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism. 
  • Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease. 
  • Genetic predisposition to higher blood pressure increases coronary artery disease risk. 
  • Genetic risk factors for perinatally acquired HIV-1 infection. 
  • Genetic signatures of exceptional longevity in humans. 
  • Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism. 
  • Genetic trade-offs and conditional neutrality contribute to local adaptation. 
  • Genetic variability in beta-defensins is not associated with susceptibility to Staphylococcus aureus bacteremia. 
  • Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. 
  • Genetic variants in ERCC1 and XPC predict survival outcome of non-small cell lung cancer patients treated with platinum-based therapy. 
  • Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survival. 
  • Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival. 
  • Genetic variants in nucleotide excision repair pathway predict survival of esophageal squamous cell cancer patients receiving platinum-based chemotherapy. 
  • Genetic variants in the H2AFX promoter region are associated with risk of sporadic breast cancer in non-Hispanic white women aged  
  • Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population. 
  • Genetic variants in the TEP1 gene are associated with prostate cancer risk and recurrence. 
  • Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. 
  • Genetic variants of SDCCAG8 and MAGI2 in mitosis-related pathway genes are independent predictors of cutaneous melanoma-specific survival. 
  • Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic Whites: a case-control study. 
  • Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma. 
  • Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes. 
  • Genetic variation in human NPY expression affects stress response and emotion. 
  • Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia. 
  • Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. 
  • Genetics of drought adaptation in Arabidopsis thaliana: I. Pleiotropy contributes to genetic correlations among ecological traits. 
  • Genetics of hybrid male sterility among strains and species in the Drosophila pseudoobscura species group. 
  • Genetics of resistance to the rust fungus Coleosporium ipomoeae in three species of morning glory (Ipomoea). 
  • Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium. 
  • Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. 
  • Genome-wide analysis identified abundant genetic modulators of contributions of the apolipoprotein E alleles to Alzheimer's disease risk. 
  • Genome-wide association study and meta-analysis of intraocular pressure. 
  • Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. 
  • Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. 
  • Genome-wide association study identifies a novel locus for cannabis dependence. 
  • Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. 
  • Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia. 
  • Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma. 
  • Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. 
  • Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. 
  • Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA. 
  • Genome-wide identification of autosomal genes with allelic imbalance of chromatin state. 
  • Genome-wide linkage scan for prostate cancer susceptibility genes in men with aggressive disease: significant evidence for linkage at chromosome 15q12. 
  • Genome-wide meta-analyses identify multiple loci associated with smoking behavior. 
  • Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. 
  • Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. 
  • Genome-wide study of methotrexate clearance replicates SLCO1B1. 
  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 
  • Genomic approaches for understanding the genetics of complex disease. 
  • Genomic cloning of hGSTP1*C, an allelic human Pi class glutathione S-transferase gene variant and functional characterization of its retinoic acid response elements. 
  • Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage. 
  • Genomic impacts of chromosomal inversions in parapatric Drosophila species. 
  • Genomic map of candidate human imprint control regions: the imprintome. 
  • Genomic sequencing is required for identification of tuberculosis transmission in Hawaii. 
  • Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles. 
  • Genomics of human health and aging. 
  • Genotypic diversity within a natural coastal bacterioplankton population. 
  • Genotypic effect of the -565C>T polymorphism in the ABCA1 gene promoter on ABCA1 expression and severity of atherosclerosis. 
  • Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion. 
  • Gigantic splenomegaly in a 27-year-old male of South-East Asian descent with concurrent diagnosis of myeloproliferative neoplasm and hemoglobin H disease. 
  • Global Survey of Variation in a Human Olfactory Receptor Gene Reveals Signatures of Non-Neutral Evolution. 
  • Globoid cell leukodystrophy (Krabbe disease): normal umbilical cord blood galactocerebrosidase activity and polymorphic mutations. 
  • Glutamate decarboxylase is not genetically linked to pyridoxine-dependent seizures. 
  • Glycogen storage disease type I: diagnosis and phenotype/genotype correlation. 
  • Grade-of-membership sibpair linkage analysis maps IDDM11 to chromosome 14q24.3-q31. 
  • Grade-specific prostate cancer associations of IGF1 (CA)19 repeats and IGFBP3-202A/C in blacks and whites. 
  • Graft donor selection based upon single locus (haplotype) analysis within families. 
  • Growth inhibition of a human lung adenocarcinoma cell line by genetic complementation with chromosome 11. 
  • GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China. 
  • HIV-1 gp140 epitope recognition is influenced by immunoglobulin DH gene segment sequence. 
  • HL-A antigenic loss in malignant transformation. 
  • HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition. 
  • HLA-DM polymorphism and risk of trichloroethylene induced medicamentosa-like dermatitis. 
  • HLA-DQA1 and APOL1 as Risk Loci for Childhood-Onset Steroid-Sensitive and Steroid-Resistant Nephrotic Syndrome. 
  • HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome. 
  • HLA-DR15 haplotype and multiple sclerosis: a HuGE review. 
  • Ha-ras polymorphisms in epithelial ovarian cancer. 
  • Haplotype associations with quantitative traits in the presence of complex multilocus and heterogeneous effects. 
  • Haplotype of signal transducer and activator of transcription 3 gene predicts cardiovascular disease in dialysis patients. 
  • Haptoglobin Genotype as a Prognostic Factor for Adverse Events in Coronary Artery Bypass Surgery in Diabetic Patients. 
  • Haptoglobin genotype and aneurysmal subarachnoid hemorrhage: Individual patient data analysis. 
  • Hardy-Weinberg testing for HLA class II (DRB1, DQA1, DQB1, and DPB1) loci in 26 human ethnic groups. 
  • Hb Catonsville (glutamic acid inserted between Pro-37(C2)alpha and Thr-38(C3)alpha). Nonallelic gene conversion in the globin system? 
  • Hepatic and neuromuscular forms of glycogen storage disease type IV caused by mutations in the same glycogen-branching enzyme gene. 
  • Heritable individual-specific and allele-specific chromatin signatures in humans. 
  • Hierarchy of risk of childhood-onset rheumatoid arthritis conferred by HLA-DRB1 alleles encoding the shared epitope. 
  • High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae. 
  • High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer. 
  • High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. 
  • High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer. 
  • High-frequency actionable pathogenic exome variants in an average-risk cohort. 
  • High-throughput genotyping with single nucleotide polymorphisms. 
  • Hmo1p, a high mobility group 1/2 homolog, genetically and physically interacts with the yeast FKBP12 prolyl isomerase. 
  • Home surveillance program prevents interstage mortality after the Norwood procedure. 
  • Homothallic conversions of yeast mating-type genes occur by intrachromosomal recombination. 
  • Host APOL1 genotype is independently associated with proteinuria in HIV infection. 
  • How genes influence life span: the biodemography of human survival. 
  • How petals change their spots: cis-regulatory re-wiring in Clarkia (Onagraceae). 
  • Human Leukocyte Antigen B*14:01 and B*35:01 Are Associated With Trimethoprim-Sulfamethoxazole Induced Liver Injury. 
  • Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. 
  • Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. 
  • Human genetic admixture. 
  • Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia. 
  • Human leukocyte antigen class II alleles are associated with risk of alopecia areata. 
  • Human leukocyte antigen matching and fetal loss: results of a 10 year prospective study. 
  • Hypertension and albuminuria in chronic kidney disease mapped to a mouse chromosome 11 locus. 
  • IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria. 
  • IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils. 
  • IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. 
  • ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. 
  • Ice-age survival of Atlantic cod: agreement between palaeoecology models and genetics. 
  • Id3 and Id2 act as a dual safety mechanism in regulating the development and population size of innate-like γδ T cells. 
  • Identification and functional study of a mild allele of SlDELLA gene conferring the potential for improved yield in tomato. 
  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 
  • Identification of E2F target genes that are rate limiting for dE2F1-dependent cell proliferation. 
  • Identification of Reduced ERAP2 Expression and a Novel HLA Allele as Components of a Risk Score for Susceptibility to Liver Injury Due to Amoxicillin-Clavulanate. 
  • Identification of a naturally occurring 21 bp deletion in alpha 2c noradrenergic receptor gene and cognitive correlates to antipsychotic treatment. 
  • Identification of a new autosomal dominant limb-girdle muscular dystrophy locus on chromosome 7. 
  • Identification of a new mutation in medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. 
  • Identification of amygdala-expressed genes associated with autism spectrum disorder. 
  • Identification of cis-suppression of human disease mutations by comparative genomics. 
  • Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines. 
  • Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. 
  • Identification of new mamu-DRB alleles using DGGE and direct sequencing. 
  • Identification of quantitative trait loci influencing wood specific gravity in an outbred pedigree of loblolly pine. 
  • Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. 
  • Identification of six new susceptibility loci for invasive epithelial ovarian cancer. 
  • Identification of susceptibility loci contributing to a complex disease using conventional segregation, linkage, and association methods. 
  • Identification of the sex genes in an early diverged fungus. 
  • IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis. 
  • Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing. 
  • Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. 
  • Immunodominance and cross-reactivity of B5703-restricted CD8 T lymphocytes from HIV type 1 subtype C-infected Ethiopians. 
  • Immunogenetic studies in families of children with juvenile dermatomyositis. 
  • Immunogenetics of consanguineous allografts in man. I. Histocompatibility testing and skin allografts. 
  • Immunogenetics of consanguineous allografts in man. II. Correlation of renal allografting with HL-A genotyping. 
  • Immunomodulatory roles of surfactant proteins A and D: implications in lung disease. 
  • Impact of APOE in mild cognitive impairment. 
  • Impact of BDNF Val66Met and 5-HTTLPR polymorphism variants on neural substrates related to sadness and executive function. 
  • Impact of CYP2C19 Metabolizer Status on Patients With ACS Treated With Prasugrel Versus Clopidogrel. 
  • Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study. 
  • Impact of measurement error on testing genetic association with quantitative traits. 
  • Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis. 
  • Importance sampling for the infinite sites model. 
  • Imprinting evolution and the price of silence. 
  • Impulsivity and genetic variants in DRD2 and ANKK1 moderate longitudinal associations between sleep problems and overweight from ages 5 to 11. 
  • In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase. 
  • Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf. 
  • Inbreeding load, average dominance and the mutation rate for mildly deleterious alleles in Mimulus guttatus. 
  • Incidentally identified genetic variants in arrhythmogenic right ventricular cardiomyopathy-associated genes among children undergoing exome sequencing reflect healthy population variation. 
  • Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms. 
  • Increased plasma thrombospondin-1 (TSP-1) levels are associated with the TNF alpha-308A allele in children with juvenile dermatomyositis. 
  • Indirect evolution of hybrid lethality due to linkage with selected locus in Mimulus guttatus 
  • Individual common variants exert weak effects on the risk for autism spectrum disorders. 
  • Induction of tolerance to parental parathyroid grafts using allogeneic thymus tissue in patients with DiGeorge anomaly. 
  • Inference on haplotype/disease association using parent-affected-child data: the projection conditional on parental haplotypes method. 
  • Inflammation and Immune Response in Arrhythmogenic Cardiomyopathy: State-of-the-Art Review. 
  • Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. 
  • Influence of CYP2C19*2 and *3 loss-of-function alleles on the pharmacodynamic effects of standard- and high-dose clopidogrel in East Asians undergoing percutaneous coronary intervention: the results of the ACCEL-DOUBLE-2N3 study. 
  • Influence of HLA-C expression level on HIV control. 
  • Influence of host genotype on progression to acquired immunodeficiency syndrome among children infected with human immunodeficiency virus type 1. 
  • Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. 
  • Inherited frailty. ApoE alleles determine survival after a diagnosis of heart disease or stroke at ages 85+. 
  • Inherited human complement C5 deficiency. Nonsense mutations in exons 1 (Gln1 to Stop) and 36 (Arg1458 to Stop) and compound heterozygosity in three African-American families. 
  • Inherited variants in regulatory T cell genes and outcome of ovarian cancer. 
  • Initiation of metastatic breast carcinoma by targeting of the ductal epithelium with adenovirus-cre: a novel transgenic mouse model of breast cancer. 
  • Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel. 
  • Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects. 
  • Integrative genomic approaches identify IKBKE as a breast cancer oncogene. 
  • Inter-chromosomal level of genome organization and longevity-related phenotypes in humans. 
  • Interaction Between Peroxisome Proliferator Activated Receptor δ and Epithelial Membrane Protein 2 Polymorphisms Influences HDL-C Levels in the Chinese Population. 
  • Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. 
  • Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study. 
  • Interactions between genotype and depressive symptoms on obesity. 
  • Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults. 
  • Interferon-beta1A-induced polyarthritis in a patient with the HLA-DRB1*0404 allele. 
  • Intergenerational continuity in parents' and adolescents' externalizing problems: The role of life events and their interaction with GABRA2. 
  • Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines. 
  • Interpretation of simultaneous linkage and family-based association tests in genome screens. 
  • Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene. 
  • Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. 
  • Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models. 
  • Intrachromosomal gene conversion and the maintenance of sequence homogeneity among repeated genes. 
  • Intraspecific variation in symbiont genomes: bottlenecks and the aphid-buchnera association. 
  • Investigations using a novel monoclonal antibody to the glycosylphosphatidylinositol-anchored protein that carries Gregory, Holley, and Dombrock blood group antigens. 
  • Involvement of histocompatibility antigens in embryonic cell recognition events. 
  • Ir genes of different high responder haplotypes for staphylococcal nuclease are not allelic. 
  • Is local adaptation in Mimulus guttatus caused by trade-offs at individual loci? 
  • Is the APOE epsilon4 genotype associated with higher hospital costs among elderly patients? 
  • Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice. 
  • Isolated sulfite oxidase deficiency: review of two cases in one family. 
  • Isolation and characterization of cul1-7, a recessive allele of CULLIN1 that disrupts SCF function at the C terminus of CUL1 in Arabidopsis thaliana. 
  • Isolation and characterization of effector-loop mutants of CDC42 in yeast. 
  • Joint effects of smoking history and APOE genotypes in age-related macular degeneration. 
  • Joint influence of small-effect genetic variants on human longevity. 
  • K Locus Effects in Gray Wolves: Experimental Assessment of TLR3 Signaling and the Gene Expression Response to Canine Distemper Virus. 
  • Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains. 
  • LIM homeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system. 
  • LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer. 
  • LW protein: a promiscuous integrin receptor activated by adrenergic signaling. 
  • Lack of association between UBQLN1 and Alzheimer disease. 
  • Lack of association between apolipoprotein E genotype and sporadic amyotrophic lateral sclerosis. 
  • Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease. 
  • Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations. 
  • Lack of genomic imprinting of DNA primase, polypeptide 2 (PRIM2) in human term placenta and white blood cells. 
  • Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia. 
  • Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. 
  • Large-scale gene-centric analysis identifies novel variants for coronary artery disease. 
  • Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. 
  • Late onset N-acetylglutamate synthase deficiency caused by hypomorphic alleles. 
  • Length Polymorphisms in the Angiotensin I-Converting Enzyme Gene and the Serotonin-Transporter-Linked Polymorphic Region Constitute a Risk Haplotype for Depression in Patients with Coronary Artery Disease. 
  • Life history in a model system: opening the black box with Arabidopsis thaliana. 
  • Life, diversity and the pursuit of haplotypes. 
  • Linkage disequilibrium and haplotype tagging polymorphisms in the Tau H1 haplotype. 
  • Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism families. 
  • Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse. 
  • Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity. The Multiple Sclerosis Genetics Group. 
  • Lipid levels are associated with a regulatory polymorphism of the monoamine oxidase-A gene promoter (MAOA-uVNTR). 
  • Localization of a gene (CMT2A) for autosomal dominant Charcot-Marie-Tooth disease type 2 to chromosome 1p and evidence of genetic heterogeneity. 
  • Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. 
  • Loss of Drosophila melanogaster p21-activated kinase 3 suppresses defects in synapse structure and function caused by spastin mutations. 
  • Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations. 
  • Loss of heterozygosity for 10q loci in human gliomas. 
  • Loss of heterozygosity on chromosome 17q11-21 in cancers of women who have both breast and ovarian cancer. 
  • Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations. 
  • Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E epsilon 4 allele. 
  • MHC class I-peptide interactions and TCR recognition. 
  • MHC class II alleles associated with clinical and immunological manifestations of HIV-1 infection among children in Catalonia, Spain. 
  • MHC-restricted recognition of autologous melanoma by tumor-specific cytotoxic T cells. Evidence for restriction by a dominant HLA-A allele. 
  • Macroecological patterns of genetic structure and diversity in the aquatic moss Platyhypnidium riparioides. 
  • Major LOXL1 risk allele is reversed in exfoliation glaucoma in a black South African population. 
  • Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses. 
  • Malaria protection due to sickle haemoglobin depends on parasite genotype. 
  • Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes. 
  • Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case-control study of African Americans and whites. 
  • Mapping and characterization of structural variation in 17,795 human genomes. 
  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia. 
  • Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. 
  • Mapping of psoriasis to 17q terminus. 
  • Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice. 
  • Mating pair formation homologue TraG is a variable membrane protein essential for contact-independent type IV secretion of chromosomal DNA by Neisseria gonorrhoeae. 
  • Mating-Type-Specific Ribosomal Proteins Control Aspects of Sexual Reproduction in Cryptococcus neoformans. 
  • Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes. 
  • Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans. 
  • Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer. 
  • Matroshka and ectopic polymorphisms: Two new classes of DNA sequence variation identified at the Van der Woude syndrome locus on 1q32-q41. 
  • Measuring the genetic influence in modulating the human life span: gene-environment interaction and the sex-specific genetic effect. 
  • Mechanisms for dominance: Adh heterodimer formation in heterozygotes between ENU or X-ray induced null alleles and normal alleles in Drosophila melanogaster. 
  • Medical genetics: a marker for Stevens-Johnson syndrome. 
  • Meiotic mutants that cause a polar decrease in recombination on the X chromosome in Caenorhabditis elegans. 
  • Meiotic recombination between dispersed repeated genes is associated with heteroduplex formation. 
  • Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele. 
  • Meta-analysis and pooled analysis of GSTM1 and CYP1A1 polymorphisms and oral and pharyngeal cancers: a HuGE-GSEC review. 
  • Meta-analysis of cardiomyopathy-associated variants in troponin genes identifies loci and intragenic hot spots that are associated with worse clinical outcomes. 
  • Methadone N-demethylation by the common CYP2B6 allelic variant CYP2B6.6. 
  • Methods for precise sizing, automated binning of alleles, and reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers. FUSION (Finland-U.S. Investigation of NIDDM Genetics) Study Group. 
  • Methylation of TFPI-2 gene is not the sole cause of its silencing. 
  • Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis. 
  • Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population. 
  • Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models. 
  • MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes. 
  • Mineralocorticoid receptor Iso/Val (rs5522) genotype moderates the association between previous childhood emotional neglect and amygdala reactivity. 
  • Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B∗35:02 as a risk factor. 
  • Missense mutations in TCF8 cause late-onset Fuchs corneal dystrophy and interact with FCD4 on chromosome 9p. 
  • Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease. 
  • Mitotic recombination within the centromere of a yeast chromosome. 
  • Modeling Glaucoma: Retinal Ganglion Cells Generated from Induced Pluripotent Stem Cells of Patients with SIX6 Risk Allele Show Developmental Abnormalities. 
  • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction. 
  • Molecular analysis of HLA-B35 alleles and their relationship to HLA-B15 alleles. 
  • Molecular analysis of alcohol dehydrogenase electromorphs in wild type and transformed Drosophila melanogaster. 
  • Molecular and clinical analysis of ALPL in a cohort of patients with suspicion of Hypophosphatasia. 
  • Molecular and clonal evolution in recurrent metastatic gliosarcoma. 
  • Molecular basis for hair loss in mice carrying a novel nonsense mutation (Hrrh-R ) in the hairless gene (Hr). 
  • Molecular basis for paradoxical carriers of adenosine deaminase (ADA) deficiency that show extremely low levels of ADA activity in peripheral blood cells without immunodeficiency. 
  • Molecular cloning of sequences from a Drosophila RNA polymerase II locus by P element transposon tagging. 
  • Molecular footprint of Medawar's mutation accumulation process in mammalian aging. 
  • Molecular genetic studies of major histocompatibility complex genes in children with juvenile dermatomyositis: increased risk associated with HLA-DQA1 *0501. 
  • Molecular genetic testing for fragile X syndrome: laboratory performance on the College of American Pathologists proficiency surveys (2001-2009). 
  • Molecular genetics of successful smoking cessation: convergent genome-wide association study results. 
  • Molecular organization and alternative splicing in zipper, the gene that encodes the Drosophila non-muscle myosin II heavy chain. 
  • Molybdopterin synthase mutations in a mild case of molybdenum cofactor deficiency. 
  • Morphological and genomic characterization of Filobasidiella depauperata: a homothallic sibling species of the pathogenic cryptococcus species complex. 
  • Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. 
  • Mouse Cntnap2 and Human CNTNAP2 ASD Alleles Cell Autonomously Regulate PV+ Cortical Interneurons. 
  • Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation. 
  • Mouse small eye results from mutations in a paired-like homeobox-containing gene. 
  • MspI RFLP for microtubule associated protein-2 (MAP2). 
  • Multi-allelic major effect genes interact with minor effect QTLs to control adaptive color pattern variation in Heliconius erato. 
  • Multiethnic polygenic risk scores improve risk prediction in diverse populations. 
  • Multilocus mapping of the X-linked hypophosphatemic rickets gene. 
  • Multiple Functional Variants in cis Modulate PDYN Expression. 
  • Multiple mutations and mutation combinations in the sodium channel of permethrin resistant mosquitoes, Culex quinquefasciatus. 
  • Mutagenic effects of abasic and oxidized abasic lesions in Saccharomyces cerevisiae. 
  • Mutant alleles of the meiotic locus, mei-9, differ in degree of effects on rod chromosome magnification and ring chromosome transmission in Drosophila. 
  • Mutation and evolution of microsatellites in Drosophila melanogaster. 
  • Mutation and expression analysis of the endoglin gene in hereditary hemorrhagic telangiectasia reveals null alleles. 
  • Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May-Hegglin anomaly. 
  • Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis. 
  • Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma. 
  • Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: report from an International DLBCL Rituximab-CHOP Consortium Program Study. 
  • Mutations in eukaryotic release factors 1 and 3 act as general nonsense suppressors in Drosophila. 
  • Mutations in medium chain acyl-CoA dehydrogenase deficiency. 
  • Mutations in purine nucleoside phosphorylase deficiency. 
  • Mutations in the TSGA14 gene in families with autism spectrum disorders. 
  • Mutations in the glucose-6-phosphatase gene are associated with glycogen storage disease types 1a and 1aSP but not 1b and 1c. 
  • Mutations in the medium chain acyl-CoA dehydrogenase (MCAD) gene. 
  • Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. 
  • Mutations of the E-cadherin gene in human gynecologic cancers. 
  • Myotilin is mutated in limb girdle muscular dystrophy 1A. 
  • NOS2A and the modulating effect of cigarette smoking in Parkinson's disease. 
  • Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements. 
  • Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume. 
  • Natural genetic variation of integrin alpha L (Itgal) modulates ischemic brain injury in stroke. 
  • Natural variation in HIV-1 protease, Gag p7 and p6, and protease cleavage sites within gag/pol polyproteins: amino acid substitutions in the absence of protease inhibitors in mothers and children infected by human immunodeficiency virus type 1. 
  • Naturally occurring amino acid polymorphisms in human immunodeficiency virus type 1 (HIV-1) Gag p7(NC) and the C-cleavage site impact Gag-Pol processing by HIV-1 protease. 
  • Neovascular age-related macular degeneration and its association with LOC387715 and complement factor H polymorphism. 
  • Neural mechanisms of genetic risk for impulsivity and violence in humans. 
  • Neural mechanisms underlying 5-HTTLPR-related sensitivity to acute stress. 
  • Neural tube defects and folate pathway genes: family-based association tests of gene-gene and gene-environment interactions. 
  • Neuroendocrine gene polymorphisms and susceptibility to juvenile idiopathic arthritis. 
  • Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis. 
  • Neutral evolution of the nonbinding region of the anthocyanin regulatory gene Ipmyb1 in Ipomoea. 
  • Newborn, carrier, and early childhood screening recommendations for fragile X. 
  • Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection. 
  • Next-generation genotyping of hypervariable loci in many individuals of a non-model species: technical and theoretical implications. 
  • Next‐generation polyploid phylogenetics: Rapid resolution of hybrid polyploid complexes using PacBio single‐molecule sequencing 
  • Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain. 
  • Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans. 
  • Nitric oxide synthase type 2 promoter polymorphisms, nitric oxide production, and disease severity in Tanzanian children with malaria. 
  • No association between Parkinson disease alleles and the risk of melanoma. 
  • No association between the HLA-A2 allele and Alzheimer disease. 
  • No association of 9p21 with arterial elasticity and retinal microvascular findings. 
  • No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients. 
  • No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease. 
  • No relationship between ovarian cancer risk and progesterone receptor gene polymorphism in a population-based, case-control study in North Carolina. 
  • Nomenclature for alleles of the human carboxylesterase 1 gene. 
  • Nomenclature relating to restriction of modified DNA in Escherichia coli. 
  • Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis. 
  • Nonlinear developmental processes as sources of dominance. 
  • Nonmuscle myosin II is required for cell proliferation, cell sheet adhesion and wing hair morphology during wing morphogenesis. 
  • Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene. 
  • Normal spastin gene dosage is specifically required for axon regeneration. 
  • Novel Genetic Loci Associated With Retinal Microvascular Diameter. 
  • Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication. 
  • Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence. 
  • Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans. 
  • Novelty seeking and the dopamine D4 receptor gene (DRD4) revisited in Asians: haplotype characterization and relevance of the 2-repeat allele. 
  • Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. 
  • Obesity and diabetes genetic variants associated with gestational weight gain. 
  • On the evolution of genetic incompatibility systems. V. Origin of sporophytic self-incompatibility in response to overdominance in viability. 
  • One haploid parent contributes 100% of the gene pool for a widespread species in northwest North America. 
  • Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits. 
  • Opposing effects of the D70 mutation and the shared epitope in HLA-DR4 on disease activity and certain disease phenotypes in rheumatoid arthritis. 
  • Ordered subset analysis for case-control studies. 
  • Ordered-subset analysis (OSA) for family-based association mapping of complex traits. 
  • Origins and prevalence of the American Founder Mutation of MSH2. 
  • Origins, genetic structure, and systematics of the narrow endemic peatmosses (Sphagnum): S. guwassanense and S. triseriporum (Sphagnaceae). 
  • Osteopontin polymorphisms and disease course in multiple sclerosis. 
  • Outcome of hematopoietic cell transplantation for DNA double-strand break repair disorders. 
  • Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study. 
  • PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia. 
  • PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: summary of the literature and implications for genetic testing. 
  • Pain perception is altered by a nucleotide polymorphism in SCN9A. 
  • Parkin mutations and susceptibility alleles in late-onset Parkinson's disease. 
  • Pars planitis: clinical features and class II HLA associations. 
  • Partial correction of endogenous DeltaF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing. 
  • Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors. 
  • Patterns of brain activation in people at risk for Alzheimer's disease. 
  • Patterns of variation within self-incompatibility loci. 
  • Pedigree generation for analysis of genetic linkage and association. 
  • Periodic vestibulocerebellar ataxia, an autosomal dominant ataxia with defective smooth pursuit, is genetically distinct from other autosomal dominant ataxias. 
  • Persistent Bacillus cereus Bacteremia in 3 Persons Who Inject Drugs, San Diego, California, USA. 
  • Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response. 
  • Pharmacogenetics goes 3D. 
  • Pharmacokinetics and safety of intravenous voriconazole in children after single- or multiple-dose administration. 
  • Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer. 
  • Phenotype analysis of patients with the risk variant LOC387715 (A69S) in age-related macular degeneration. 
  • Phosphoregulation provides specificity to biomolecular condensates in the cell cycle and cell polarity. 
  • Physical Crossmatching vs Virtual Crossmatching: The end of an era? or Why give up a good thing? 
  • Plasminogen alleles influence susceptibility to invasive aspergillosis. 
  • Platelet PlA2 polymorphism and platelet activation are associated with increased troponin I release after cardiopulmonary bypass. 
  • Platelet PlA2 polymorphism enhances risk of neurocognitive decline after cardiopulmonary bypass. Multicenter Study of Perioperative Ischemia (McSPI) Research Group. 
  • Pleiotropic effects of an allele producing white flowers in Ipomoea purpurea. 
  • Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. 
  • Pollinator-mediated selection on flower color allele drives reinforcement. 
  • Polychaetoid is required to restrict segregation of sensory organ precursors from proneural clusters in Drosophila. 
  • Polygenic risk score for disability and insights into disability-related molecular mechanisms. 
  • Polygenic risk scores: pleiotropy and the effect of environment. 
  • Polymorphic hCHK2/hCds1 codon 84 allele and risk of squamous cell carcinoma of the head and neck--a case-control analysis. 
  • Polymorphic mimicry in Papilio dardanus: mosaic dominance, big effects, and origins. 
  • Polymorphism in the serotonin transporter gene and response to treatment in African American cocaine and alcohol-abusing individuals. 
  • Polymorphism of DNA ligase I and risk of lung cancer--a case-control analysis. 
  • Polymorphism of angiotensin converting enzyme gene is associated with circulating levels of plasminogen activator inhibitor-1. 
  • Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use. 
  • Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population. 
  • Polymorphisms in HLA class I genes associated with both favorable prognosis of human immunodeficiency virus (HIV) type 1 infection and positive cytotoxic T-lymphocyte responses to ALVAC-HIV recombinant canarypox vaccines. 
  • Polymorphisms in NF-kappaB inhibitors and risk of epithelial ovarian cancer. 
  • Polymorphisms in TCEAL7 and risk of epithelial ovarian cancer. 
  • Polymorphisms in genes encoding drug metabolizing enzymes and their influence on the outcome of children with neuroblastoma. 
  • Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the Ovarian Cancer Association Consortium. 
  • Polymorphisms in the kinesin-like factor 1 B gene and risk of epithelial ovarian cancer in Eastern Chinese women. 
  • Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: a case-control study. 
  • Polymorphisms of cytosolic serine hydroxymethyltransferase and risk of lung cancer: a case-control analysis. 
  • Polymorphisms of the FAS and FAS ligand genes associated with risk of cutaneous malignant melanoma. 
  • Polymorphisms of the scavenger receptor class B member 1 are associated with insulin resistance with evidence of gene by sex interaction. 
  • Polymorphisms of vitamin D receptor gene protect against the risk of head and neck cancer. 
  • Population frequencies of the Triallelic 5HTTLPR in six Ethnicially diverse samples from North America, Southeast Asia, and Africa. 
  • Possible interaction of genotypes at cystathionine beta-synthase and methylenetetrahydrofolate reductase (MTHFR) in neural tube defects. NTD Collaborative Group. 
  • Posttranslational regulation of TCR Valpha allelic exclusion during T cell differentiation. 
  • Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer. 
  • Potentially functional genetic variants in PLIN2, SULT2A1 and UGT1A9 genes of the ketone pathway and survival of nonsmall cell lung cancer. 
  • Potentially functional polymorphisms in the CASP7 gene contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population. 
  • Predicting HLA genotypes using unphased and flanking single-nucleotide polymorphisms in Han Chinese population. 
  • Predictors of cognitive decline after cardiac operation. 
  • Predictors of variation in serum IGF1 and IGFBP3 levels in healthy African American and white men. 
  • Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center. 
  • Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative peak serum creatinine concentrations in cardiac surgical patients. 
  • Prenatal detection of an inherited Duchenne muscular dystrophy deletion allele. 
  • Prenatal exclusion of Ehlers-Danlos syndrome type VI by mutational analysis. 
  • Presence of large deletions in kindreds with autism. 
  • Presenilin-1 polymorphism and Alzheimer's disease. 
  • Presymptomatic and prenatal diagnosis in myotonic dystrophy by genetic linkage studies. 
  • Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder. 
  • Prevalence of the HOXB13 G84E prostate cancer risk allele in men treated with radical prostatectomy. 
  • Primary immunodeficiency mutation databases. 
  • Probing structure-function relationships in missense variants in the carboxy-terminal region of BRCA1. 
  • Problems meeting basic needs moderate the association between the APOE epsilon4 allele and cognitive decline. 
  • Progression of cognitive, functional, and neuropsychiatric symptom domains in a population cohort with Alzheimer dementia: the Cache County Dementia Progression study. 
  • Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal. 
  • Proper multivariate conditional autoregressive models for spatial data analysis. 
  • Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms. 
  • Protective association of the ε2/ε3 heterozygote with Alzheimer's disease is strengthened by TOMM40-APOE variants in men. 
  • Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. 
  • Protective role of the apolipoprotein E2 allele in age-related disease traits and survival: evidence from the Long Life Family Study. 
  • Psychosocial and biobehavioral factors and their interplay in coronary heart disease. 
  • Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics. 
  • Puzzling role of genetic risk factors in human longevity: "risk alleles" as pro-longevity variants. 
  • QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival. 
  • Quantitative DNA pooling to increase the efficiency of linkage analysis in autosomal dominant disease. 
  • Quantitative detection of RASSF1A DNA promoter methylation in tumors and serum of patients with serous epithelial ovarian cancer. 
  • Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association. 
  • Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22. 
  • RECQ1 A159C Polymorphism Is Associated With Overall Survival of Patients With Resected Pancreatic Cancer: A Replication Study in NRG Oncology Radiation Therapy Oncology Group 9704. 
  • RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro. 
  • RSSs set the odds for exclusion. 
  • Rab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectoderm. 
  • RacGap50C negatively regulates wingless pathway activity during Drosophila embryonic development. 
  • Racial differences in the influence of the APOE epsilon 4 allele on cognitive decline in a sample of community-dwelling older adults. 
  • Rapid and slow progressors differ by a single MHC class I haplotype in a family of MHC-defined rhesus macaques infected with SIV. 
  • Rapid detection of the Fc gamma RIIA-H/R 131 ligand-binding polymorphism using an allele-specific restriction enzyme digestion (ASRED). 
  • Rare and low-frequency coding variants alter human adult height. 
  • Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. 
  • Recent divergence, intercontinental dispersal and shared polymorphism are shaping the genetic structure of amphi-Atlantic peatmoss populations. 
  • Receptor quality control in the endoplasmic reticulum for plant innate immunity. 
  • Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder. 
  • Recombination between genes located on nonhomologous chromosomes in Saccharomyces cerevisiae. 
  • Recombination of 4p16 DNA markers in an unusual family with Huntington disease. 
  • Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers. 
  • Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants. 
  • Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 
  • Regulation of E2A gene expression in B-lymphocyte development. 
  • Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility. 
  • Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene. 
  • Relationship between serotonin transporter gene polymorphisms and platelet serotonin transporter sites among African-American cocaine-dependent individuals and healthy volunteers. 
  • Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery. 
  • Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae. 
  • Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Repeat polymorphisms within gene regions: phenotypic and evolutionary implications. 
  • Replication studies in longevity: puzzling findings in Danish centenarians at the 3'APOB-VNTR locus. 
  • Requirement for the vasa RNA helicase in gurken mRNA localization. 
  • Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci. 
  • Risk alleles for multiple sclerosis identified by a genomewide study. 
  • Risk of Alzheimer disease with the epsilon4 allele for apolipoprotein E in a population-based study of men aged 62-73 years. 
  • Role for rearranged variable gene segments in directing secondary T cell receptor alpha recombination. 
  • Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae. 
  • Role of GABRA2 in trajectories of externalizing behavior across development and evidence of moderation by parental monitoring. 
  • Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. 
  • Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast. 
  • Role of β-3 adrenergic receptor polymorphism in overactive bladder. 
  • Roles for the winged helix transcription factors MF1 and MFH1 in cardiovascular development revealed by nonallelic noncomplementation of null alleles. 
  • Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae. 
  • S-allele diversity in a natural population of Physalis crassifolia (Solanaceae) (ground cherry) assessed by RT-PCR. 
  • S-allele sequence diversity in natural populations of Solanum carolinense (Horsenettle). 
  • SLC6A4 variation and citalopram response. 
  • SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization. 
  • SLCO1B1*5 Allele Is Associated With Atorvastatin Discontinuation and Adverse Muscle Symptoms in the Context of Routine Care. 
  • SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing. 
  • SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease. 
  • SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families. 
  • SNPselector: a web tool for selecting SNPs for genetic association studies. 
  • SOD2 polymorphisms: unmasking the effect of polymorphism on splicing. 
  • Schizosaccharomyces pombe Sst4p, a conserved Vps27/Hrs homolog, functions downstream of phosphatidylinositol 3-kinase Pik3p to mediate proper spore formation. 
  • Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. 
  • Segregation and linkage analysis of alpha-N-acetyl-D-glucosaminidase (NAG) levels in a black family. 
  • Segregation at three loci explains familial and population risk in Hirschsprung disease. 
  • Segregation of recombinant chromatids following mitotic crossing over in yeast. 
  • Selection of donors for kidney transplantation. 
  • Selective trade-offs maintain alleles underpinning complex trait variation in plants. 
  • Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae. 
  • Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis. 
  • Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results. 
  • Serotonin transporter genetic variation and the response of the human amygdala. 
  • Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women. 
  • Sex-induced silencing defends the genome of Cryptococcus neoformans via RNAi. 
  • Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. 
  • Sexual fidelity trade-offs promote regulatory variation in the prairie vole brain. 
  • Sickle hemoglobin (HbS) allele and sickle cell disease: a HuGE review. 
  • Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz. 
  • Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival. 
  • Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays. 
  • Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. 
  • Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. 
  • Site frequency spectra from genomic SNP surveys. 
  • Sleep quality varies as a function of 5-HTTLPR genotype and stress. 
  • Smoking, Alzheimer's disease, and confounding with genes. 
  • Social environment influences the relationship between genotype and gene expression in wild baboons. 
  • Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA. 
  • Somatic Mutations in Vascular Malformations of Hereditary Hemorrhagic Telangiectasia Result in Bi-allelic Loss of ENG or ACVRL1. 
  • Somatic uniparental disomy of Chromosome 16p in hemimegalencephaly. 
  • Sparrows and supergenes: Ecological epigenetics in action. 
  • Spatial models for hybrid zones. 
  • Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease. 
  • Spectrum of mutation and frequency of allelic deletion of the p53 gene in ovarian cancer. 
  • Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability. 
  • Spontaneous Differentiation of T Follicular Helper Cells in LATY136F Mutant Mice. 
  • Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities. 
  • Sporadic, Global Linkage Disequilibrium Between Unlinked Segregating Sites. 
  • Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations. 
  • Sry induces cell proliferation in the mouse gonad. 
  • Stac3 is a component of the excitation-contraction coupling machinery and mutated in Native American myopathy. 
  • Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing. 
  • Strain-specific spontaneous and NNK-mediated tumorigenesis in Pten+/- mice. 
  • Stress, COMT Polymorphisms, and Depressive Symptoms in Older Australian Women: An Exploratory Study. 
  • Strong founder effect in Drosophila pseudoobscura colonizing New Zealand from North America. 
  • Structure of the human allelic glutathione S-transferase-pi gene variant, hGSTP1 C, cloned from a glioblastoma multiforme cell line. 
  • Structure, function, and phylogeny of the mating locus in the Rhizopus oryzae complex. 
  • Structure-Function Analysis of Interallelic Complementation in ROOTY Transheterozygotes. 
  • Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin. 
  • Subspecific differentiation of Mycobacterium avium complex strains by automated sequencing of a region of the gene (hsp65) encoding a 65-kilodalton heat shock protein. 
  • Summarizing polygenic risks for complex diseases in a clinical whole-genome report. 
  • Survey of the fragile X syndrome and the fragile X E syndrome in a special education needs population. 
  • Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration. 
  • Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. 
  • T locus shows no evidence for linkage disequilibrium or mutation in American Caucasian neural tube defect families. 
  • TOMM40-APOE haplotypes are associated with cognitive decline in non-demented Blacks. 
  • TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. 
  • TSPEAR variants are primarily associated with ectodermal dysplasia and tooth agenesis but not hearing loss: A novel cohort study. 
  • Tagging single nucleotide polymorphisms in excision repair cross-complementing group 1 (ERCC1) and risk of primary lung cancer in a Chinese population. 
  • Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. 
  • Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma. 
  • Telomere structure and maintenance gene variants and risk of five cancer types. 
  • Temporal and molecular separation of the kit receptor tyrosine kinase's roles in zebrafish melanocyte migration and survival. 
  • Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila. 
  • The 8.5-kb PstI allele of the stress protein gene, Hsp70-2: an independent risk factor for systemic lupus erythematosus in African Americans? 
  • The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study. 
  • The APOE-E4 allele and the risk of functional decline in a community sample of African American and white older adults. 
  • The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice. 
  • The Arabidopsis F-box protein SLEEPY1 targets gibberellin signaling repressors for gibberellin-induced degradation. 
  • The Arabidopsis RGA gene encodes a transcriptional regulator repressing the gibberellin signal transduction pathway. 
  • The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory. 
  • The C282Y mutation causing hereditary hemochromatosis does not produce a null allele. 
  • The Carolina Breast Cancer Study: integrating population-based epidemiology and molecular biology. 
  • The Expanding Molecular Genetics Tool Kit in Chlamydia. 
  • The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. 
  • The FoxO3 gene and cause-specific mortality. 
  • The G72/G30 gene complex and cognitive abnormalities in schizophrenia. 
  • The LS locus of pea encodes the gibberellin biosynthesis enzyme ent-kaurene synthase A. 
  • The Marquesans at the fringes of the Austronesian expansion. 
  • The Nramp2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border. 
  • The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. 
  • The Roles of β-Oxidation and Cofactor Homeostasis in Peroxisome Distribution and Function in Arabidopsis thaliana. 
  • The S1103Y cardiac sodium channel variant is associated with implantable cardioverter-defibrillator events in blacks with heart failure and reduced ejection fraction. 
  • The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours. 
  • The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer. 
  • The accuracy of statistical estimates in genetic studies of aging can be significantly improved. 
  • The activin receptor-like kinase 1 gene: genomic structure and mutations in hereditary hemorrhagic telangiectasia type 2. 
  • The apolipoprotein E epsilon2 allele and aging-associated health deterioration in older males. 
  • The association of lumbar spondylolisthesis with collagen IX tryptophan alleles. 
  • The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development. 
  • The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression. 
  • The canine MHC class Ia allele DLA-88*508:01 presents diverse self- and canine distemper virus-origin peptides of varying length that have a conserved binding motif. 
  • The claret locus in Drosophila encodes products required for eyecolor and for meiotic chromosome segregation. 
  • The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans. 
  • The contribution of male-sterility mutations to inbreeding depression in Mimulus guttatus. 
  • The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites. 
  • The effect of oxidative metabolism on spontaneous Pol zeta-dependent translesion synthesis in Saccharomyces cerevisiae. 
  • The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes. 
  • The evolutionary dynamics of self-incompatibility systems. 
  • The genetic architecture of biofilm formation in a clinical isolate of Saccharomyces cerevisiae. 
  • The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus. 
  • The genetic architecture of type 2 diabetes. 
  • The genetic regulatory signature of type 2 diabetes in human skeletal muscle. 
  • The genetics of hybrid male sterility between the allopatric species pair Drosophila persimilis and D. pseudoobscura bogotana: dominant sterility alleles in collinear autosomal regions. 
  • The genetics of reproductive isolation and the potential for gene exchange between Drosophila pseudoobscura and D. persimilis via backcross hybrid males. 
  • The immunogenetics of the major histocompatibility chromosomal region in man. 
  • The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions. 
  • The influences on human longevity by HUMTHO1.STR polymorphism (Tyrosine Hydroxylase gene). A relative risk approach. 
  • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. 
  • The loss of a polymorphic glycosylation site caused by Thr-927-->Ile is linked to a second polymorphic Val-816-->Ile substitution in lysosomal alpha-glucosidase of American blacks. 
  • The moderating effect of the APOE [small element of] 4 allele on the relationship between hippocampal volume and cognitive decline in older depressed patients. 
  • The molecular defect in hypotransferrinemic mice. 
  • The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domain. 
  • The nature of robustness in development. 
  • The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2. 
  • The neutral theory and natural selection in the HLA region. 
  • The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7,8-dihydro-8-oxoguanine in yeast. 
  • The probability of HLA-C matching between patient and unrelated donor at the molecular level: estimations based on the linkage disequilibrium between DNA typed HLA-B and HLA-C alleles. 
  • The prognostic values of CYP2B6 genetic polymorphisms and metastatic sites for advanced breast cancer patients treated with docetaxel and thiotepa. 
  • The putative glucose 6-phosphate translocase gene is mutated in essentially all cases of glycogen storage disease type I non-a. 
  • The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila. 
  • The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction. 
  • The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection. 
  • The role of innate immunity in acute allograft rejection after lung transplantation. 
  • The role of lipid-related genes, aging-related processes, and environment in healthspan. 
  • The role of polymorphisms in circadian pathway genes in breast tumorigenesis. 
  • The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus. 
  • The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. 
  • The scale of population structure in Arabidopsis thaliana 
  • The secreted metalloprotease ADAMTS20 is required for melanoblast survival. 
  • The segment polarity phenotype of Drosophila involves differential tendencies toward transformation and cell death. 
  • The serotonin transporter gene polymorphism (5HTTLPR) moderates the effect of adolescent environmental conditions on self-esteem in young adulthood: a structural equation modeling approach. 
  • The thermolabile variant of methylenetetrahydrofolate reductase (MTHFR) is not a major risk factor for neural tube defect in American Caucasians. The NTD Collaborative Group. 
  • There is a pathologic relationship between ApoE-epsilon 4 and Alzheimer's disease. 
  • Thermosensory and nonthermosensory isoforms of Drosophila melanogaster TRPA1 reveal heat-sensor domains of a thermoTRP Channel. 
  • Thirteen Mhc-DQA1 alleles from two populations of baboons. 
  • Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk. 
  • Three-genome mosses: complex double allopolyploid origins for triploid gametophytes in Sphagnum. 
  • Tissue-specific inactivation of murine M6P/IGF2R. 
  • Tnni3k modifies disease progression in murine models of cardiomyopathy. 
  • Toward precision prescribing for methadone: Determinants of methadone deposition. 
  • Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan. 
  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. 
  • Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells. 
  • Transforming growth factor beta receptor I polyalanine repeat polymorphism does not increase ovarian cancer risk. 
  • Treatment with the nitric oxide synthase inhibitor L-NAME provides a survival advantage in a mouse model of Kras mutation-positive, non-small cell lung cancer. 
  • Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer. 
  • Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene. 
  • Turning T-cell receptor beta recombination on and off: more questions than answers. 
  • Two common endoglin mutations in families with hereditary hemorrhagic telangiectasia in the Netherlands Antilles: evidence for a founder effect. 
  • Two distinct forms of soluble MHC class I molecules synthesized by different mechanisms in normal rat cells in vitro. 
  • Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart-related traits. 
  • Unisexual reproduction drives meiotic recombination and phenotypic and karyotypic plasticity in Cryptococcus neoformans. 
  • Urinary isothiocyanates; glutathione S-transferase M1, T1, and P1 polymorphisms; and risk of colorectal cancer: the Multiethnic Cohort Study. 
  • V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity. 
  • VEGFA and VEGFR2 gene polymorphisms and response to anti-vascular endothelial growth factor therapy: comparison of age-related macular degeneration treatments trials (CATT). 
  • VKORC1 haplotypes in five East-Asian populations and Indians. 
  • Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG). 
  • Variable HLA expression on deceased donor lymphocytes: Not all crossmatches are created equal. 
  • Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer. 
  • Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. 
  • Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans. 
  • Variations of cardiovascular disease associated genes exhibit sex-dependent influence on human longevity. 
  • Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation. 
  • Vitamin D receptor alleles do not correlate with bone mineral density in premenopausal Caucasian women from the southeastern United States. 
  • WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. 
  • We need further studies for the development of "optimized antiplatelet therapy" based on ethnicity. 
  • Western-type diet modulates inflammatory responses and impairs functional outcome following permanent middle cerebral artery occlusion in aged mice expressing the human apolipoprotein E4 allele. 
  • Whole genome sequence analysis of blood lipid levels in >66,000 individuals. 
  • Whole-Genome Analysis Illustrates Global Clonal Population Structure of the Ubiquitous Dermatophyte Pathogen Trichophyton rubrum. 
  • Whole-exome sequencing identifies novel somatic alterations associated with outcomes in idiopathic multicentric Castleman disease. 
  • Whole-exome sequencing of a pedigree segregating asthma. 
  • Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program. 
  • Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. 
  • Yeast pseudohyphal growth is regulated by GPA2, a G protein alpha homolog. 
  • [Serotonin transporter gene polymorphism and factors influencing mental and physical health in aging]. 
  • alpha AD alpha hybrids of Cryptococcus neoformans: evidence of same-sex mating in nature and hybrid fitness. 
  • miR-449b rs10061133 and miR-4293 rs12220909 polymorphisms are associated with decreased esophageal squamous cell carcinoma in a Chinese population. 
  • speck, First Identified in Drosophila melanogaster in 1910, Is Encoded by the Arylalkalamine N-Acetyltransferase (AANAT1) Gene. 
• 

  Keywords of People

  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Bowes Rickman, Catherine, George and Geneva Boguslavsky Distinguished Professor of Eye Research, Cell Biology
  • Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
  • Grambow, Steven C., Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Halabi, Susan, Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Kelsoe, Garnett H., James B. Duke Distinguished Professor of Immunology, Integrative Immunobiology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Integrative Immunobiology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • Middleton, John Paul, Professor of Medicine, Medicine, Nephrology
  • Milano, Carmelo Alessio, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics,, Molecular Genetics and Microbiology
  • Tsalik, Ephraim, Adjunct Associate Professor in the Department of Medicine, Medicine, Infectious Diseases
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology