Allergens

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  Subject Areas on Research

  • A comparison of adverse reaction rates for PAS C versus plasma platelet units. 
  • A consensus protocol for the determination of the threshold doses for allergenic foods: how much is too much? 
  • A differing pattern of association between dietary fish and allergen-specific subgroups of atopy. 
  • A major allergen involved in IgE mediated cockroach hypersensitivity is a 90 kD protein with multiple IgE binding domains. 
  • A murine model of peanut anaphylaxis: T- and B-cell responses to a major peanut allergen mimic human responses. 
  • A soybean G2 glycinin allergen. 1. Identification and characterization. 
  • A soybean G2 glycinin allergen. 2. Epitope mapping and three-dimensional modeling. 
  • Adverse reactions during peanut oral immunotherapy home dosing. 
  • Aerobic exercise attenuates airway inflammatory responses in a mouse model of atopic asthma. 
  • Age-specific profiling of cutaneous allergy at high temporal resolution suggests age-related alterations in regulatory immune function. 
  • Allergen-induced airway disease is mouse strain dependent. 
  • Allergenic ingredients in nail polishes. 
  • Allergenic potency of SMU-Df extract in comparison with VUS-Df extract; and diagnosis and immunotherapy for atopic dermatitis and rhinitis with SMU-Df extract in China. 
  • Allergenicity of major component proteins of soybean determined by enzyme-linked immunosorbent assay (ELISA) and immunoblotting in children with atopic dermatitis and positive soy challenges. 
  • Allergenicity of peanut and soybean extracts altered by chemical or thermal denaturation in patients with atopic dermatitis and positive food challenges. 
  • Allergens in Medical Hand Skin Cleansers. 
  • Allergic lung responses are increased in prostaglandin H synthase-deficient mice. 
  • Animal models of food allergy. 
  • Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. 
  • Assessment of the endogenous allergens in glyphosate-tolerant and commercial soybean varieties. 
  • Associations of neighborhood concentrated poverty, neighborhood racial/ethnic composition, and indoor allergen exposures: a cross-sectional analysis of los angeles households, 2006-2008. 
  • Atopic dermatitis and food hypersensitivity reactions. 
  • Benefits and risks in malaria control. 
  • Biochemical and structural analysis of the IgE binding sites on ara h1, an abundant and highly allergenic peanut protein. 
  • Blocking CCR7 at the ocular surface impairs the pathogenic contribution of dendritic cells in allergic conjunctivitis. 
  • Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice. 
  • Clinical efficacy and immune regulation with peanut oral immunotherapy. 
  • Common allergens in avian meats. 
  • Comparative potency of Ara h 1 and Ara h 2 in immunochemical and functional assays of allergenicity. 
  • Competitive inhibition ELISA for quantification of Ara h 1 and Ara h 2, the major allergens of peanuts. 
  • Conditional knockout of the RNA-binding protein HuR in CD4⁺ T cells reveals a gene dosage effect on cytokine production. 
  • Contamination of nebulizer equipment with cockroach allergen: there's a bug in the system! 
  • Contribution of Ara h 2 to peanut-specific, immunoglobulin E-mediated, cell activation. 
  • Depression of lymphocyte transformation and exacerbation of Behcet's syndrome by ingestion of english walnuts. 
  • Double-blind placebo-controlled trial of oral cromolyn in children with atopic dermatitis and documented food hypersensitivity. 
  • Early-life ozone exposure associated with asthma without sensitization in Latino children. 
  • Effect of combined antibacterial and antifungal treatment in severe atopic dermatitis. 
  • Effects of cooking methods on peanut allergenicity. 
  • Engineered recombinant peanut protein and heat-killed Listeria monocytogenes coadministration protects against peanut-induced anaphylaxis in a murine model. 
  • Engineering, characterization and in vitro efficacy of the major peanut allergens for use in immunotherapy. 
  • Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice. 
  • Epitope specificity and immunoaffinity purification of the major peanut allergen, Ara h I. 
  • Epitope specificity of the major peanut allergen, Ara h II. 
  • Evaluation of the adverse effects of long-term hyposensitization. 
  • Factor analysis in the Genetics of Asthma International Network family study identifies five major quantitative asthma phenotypes. 
  • Factors affecting the determination of threshold doses for allergenic foods: how much is too much? 
  • Galactose-α-1,3-galactose and delayed anaphylaxis, angioedema, and urticaria in children. 
  • Hand dermatitis: a focus on allergic contact dermatitis to biocides. 
  • Harboring of particulate allergens within secretory compartments by mast cells following IgE/FcepsilonRI-lipid raft-mediated phagocytosis. 
  • How do we know when peanut and tree nut allergy have resolved, and how do we keep it resolved? 
  • Identification and characterization of a second major peanut allergen, Ara h II, with use of the sera of patients with atopic dermatitis and positive peanut challenge. 
  • Identification and mutational analysis of the immunodominant IgE binding epitopes of the major peanut allergen Ara h 2. 
  • Identification of a major peanut allergen, Ara h I, in patients with atopic dermatitis and positive peanut challenges. 
  • Identification of peanut agglutinin and soybean trypsin inhibitor as minor legume allergens. 
  • Identification of unique peanut and soy allergens in sera adsorbed with cross-reacting antibodies. 
  • IgG and IgE avidity characteristics of peanut allergic individuals. 
  • Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy. 
  • Immunology in the Clinic Review Series; focus on allergies: immunotherapy for food allergy. 
  • Immunotherapy in the treatment of food allergy: focus on oral tolerance. 
  • Impairing oral tolerance promotes allergy and anaphylaxis: a new murine food allergy model. 
  • In vitro translation of RNA from the German cockroach Blattella germanica. 
  • In vivo and T cell cross-reactivity between walnut, cashew and peanut. 
  • Increased peanut-specific IgA levels in saliva correlate with food challenge outcomes after peanut sublingual immunotherapy. 
  • Increased response to antigen and histamine release in smaller sensitized canine bronchi. 
  • Induction and Characterization of the Allergic Eye Disease Mouse Model. 
  • Isolation of the 36-kD German (Blattella germanica) cockroach allergen using fast protein liquid chromatography. 
  • Isolation, identification, and characterization of clones encoding antigens responsible for peanut hypersensitivity. 
  • Laboratory animal allergies. Use of the radioallergosorbent test inhibition assay to monitor airborne allergen levels. 
  • Laboratory animal allergy: an update. 
  • Lack of immunogenicity of ice structuring protein type III HPLC12 preparation administered by the oral route to human volunteers. 
  • Loss of allergen 1 confers a hypervirulent phenotype that resembles mucoid switch variants of Cryptococcus neoformans. 
  • Low Serum IgE Is a Sensitive and Specific Marker for Common Variable Immunodeficiency (CVID). 
  • Lung effector memory and activated CD4+ T cells display enhanced proliferation in surfactant protein A-deficient mice during allergen-mediated inflammation. 
  • Lymphocyte responses to purified ragweed allergens in vitro. I. Proliferative responses in normal, newborn, agammaglobulinemic, and atopic subjects. 
  • Mapping and mutational analysis of the IgE-binding epitopes on Ara h 1, a legume vicilin protein and a major allergen in peanut hypersensitivity. 
  • Mast Cell Deficiency Limits the Development of Chronic Rhinosinusitis in Mice. 
  • Mast cell modulation of immune responses to bacteria. 
  • Maternal and infant diets for prevention of allergic diseases: understanding menu changes in 2008. 
  • Methacholine-induced cutaneous flare response: bivariate analysis of responsiveness and sensitivity. 
  • Microarray immunoassay: association of clinical history, in vitro IgE function, and heterogeneity of allergenic peanut epitopes. 
  • Modification of a major peanut allergen leads to loss of IgE binding. 
  • Modification of peanut allergen Ara h 3: effects on IgE binding and T cell stimulation. 
  • Molecular cloning and epitope analysis of the peanut allergen Ara h 3. 
  • Monitoring peanut allergen in food products by measuring Ara h 1. 
  • Mutational analysis of the IgE-binding epitopes of P34/Gly m Bd 30K. 
  • Nasal peanut+ CpG immunotherapy enhances peanut-specific IFN-γ in Th2 cells and IL-10 in non-Th2 cells in mice. 
  • New roles for mast cells in modulating allergic reactions and immunity against pathogens. 
  • Nocturnal awakening caused by asthma in children with mild-to-moderate asthma in the childhood asthma management program. 
  • Occupational Animal Allergy. 
  • Open-label maintenance after milk oral immunotherapy for IgE-mediated cow's milk allergy. 
  • Oral immunotherapy for food allergy. 
  • Oral immunotherapy for food allergy. 
  • Oral tolerance, food allergy, and immunotherapy: implications for future treatment. 
  • Parabens: the 2019 nonallergen of the year. 
  • Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation. 
  • Patch testing in children: not just little adults. 
  • Pathophysiology of food allergy. 
  • Peanut allergenicity. 
  • Peanut and soy allergy: a clinical and therapeutic dilemma. 
  • Peanut hypersensitivity. IgE binding characteristics of a recombinant Ara h I protein. 
  • Peanut protein allergens: the effect of roasting on solubility and allergenicity. 
  • Pediatric Baseline Patch Test Series: Pediatric Contact Dermatitis Workgroup. 
  • Pediatric food allergy and mucosal tolerance. 
  • Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles. 
  • Pollen food syndrome: update on the allergens. 
  • Predictive value of skin prick tests using recombinant allergens for diagnosis of peanut allergy. 
  • Preparation and Analysis of Peanut Flour Used in Oral Immunotherapy Clinical Trials. 
  • Pricking away at penicillin allergy with a dedicated outpatient clinic. 
  • Prospective study of breast-feeding in relation to wheeze, atopy, and bronchial hyperresponsiveness in the Avon Longitudinal Study of Parents and Children (ALSPAC). 
  • Prospective study of occupational asthma to laboratory animal allergens: stability of airway responsiveness to methacholine challenge for one year. 
  • Proteases of Dermatophagoides pteronyssinus. 
  • Protection from experimental asthma by an endogenous bronchodilator. 
  • Protein structure plays a critical role in peanut allergen stability and may determine immunodominant IgE-binding epitopes. 
  • RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation. 
  • Recombinant peanut allergen Ara h I expression and IgE binding in patients with peanut hypersensitivity. 
  • Reprograming immunity to food allergens. 
  • Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model. 
  • Respiratory symptoms among crab processing workers in Alaska: epidemiological and environmental assessment. 
  • Role of tolerance in the development of eosinophilic gastrointestinal diseases. 
  • Safety of a peanut oral immunotherapy protocol in children with peanut allergy. 
  • Safety of open food challenges in the office setting. 
  • Secondary allergic T cell responses are regulated by dendritic cell-derived thrombospondin-1 in the setting of allergic eye disease. 
  • Sensitization (IgE antibody) to food allergens in wheezing infants and children. 
  • Sensitization and allergic response and intervention therapy in animal models. 
  • Serological characteristics of peanut allergy in children. 
  • Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice. 
  • Spore persistence and likelihood of aeroallergenicity of entomopathogenic fungi used for mosquito control. 
  • Stability of patch test allergens. 
  • Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. 
  • Structure of the major peanut allergen Ara h 1 may protect IgE-binding epitopes from degradation. 
  • Sublingual versus oral immunotherapy for peanut-allergic children: a retrospective comparison. 
  • Systemic contact dermatitis: sometimes it is the food. 
  • TLR4 signaling attenuates ongoing allergic inflammation. 
  • Targeted HAS2 Expression Lessens Airway Responsiveness in Chronic Murine Allergic Airway Disease. 
  • Technical review on the management of eosinophilic esophagitis: a report from the AGA institute and the joint task force on allergy-immunology practice parameters. 
  • Tertiary structure and biophysical properties of a major peanut allergen, implications for the production of a hypoallergenic protein. 
  • The Schultz-Dale response of sensitized canine bronchial smooth muscle. 
  • The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens. 
  • The effect of serial dilution error on calibration inference in immunoassay. 
  • The future of food allergy therapeutics. 
  • The major allergen from birch tree pollen, Bet v 1, binds and permeabilizes membranes. 
  • The major glycoprotein allergen from Arachis hypogaea, Ara h 1, is a ligand of dendritic cell-specific ICAM-grabbing nonintegrin and acts as a Th2 adjuvant in vitro. 
  • The production of interferon-gamma in response to a major peanut allergy, Ara h II correlates with serum levels of IgE anti-Ara h II. 
  • Trends in nail services may cause dermatitis: not your mother's nail polish. 
  • Wheat alpha-amylase inhibitor: a second route of allergic sensitization. 
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  Keywords of People

  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine, Immunology
  • Dement, John McCray, Professor Emeritus in Family Medicine and Community Health, Family Medicine & Community Health,Occupational & Environmental Medicine